ZMP
si:dkey-25e12.6
Ensembl ID:
ZFIN ID:
Description:
Novel protein similar to methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahyd
Human Orthologues:
AL445665.1, MTHFD2, MTHFD2L
Human Descriptions:
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like [Source:HGNC Symbol;Acc:31865]
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like [Source:HGNC Symbol;Acc:31865]
Mouse Orthologues:
Mthfd2, Mthfd2l
Mouse Descriptions:
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase Ge
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like Gene [Source:MGI Symbol;Acc:MGI:191
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like Gene [Source:MGI Symbol;Acc:MGI:191
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa17397 | Essential Splice Site | Available for shipment | Available now |
| sa915 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa17397
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000147154 | Essential Splice Site | 6 | 122 | None | 5 |
| ENSDART00000147154 | Essential Splice Site | 6 | 122 | None | 5 |
The following transcripts of ENSDARG00000091891 do not overlap with this mutation:
The following genes are also affected by this mutation:
Genomic Location (Zv9):
Chromosome 20 (position 26521155)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 26592458 |
| GRCz11 | 20 | 26491548 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGAAGTTGCTGCTCAGGGAAGCCGTTTTCAGTTCCTGTATAACTTGCAGG[T/C]GAGAACAGACGCAAGTAGTTACAGTGTAGAAGAAAACAAACAAAATGATC
Long Flanking Sequence:
ATGTTCATGACAGATTTATGACAAGTTATGTTGCATTGGTTATGTTAAATTGTCATGACAAGGACATCTCAAACAGCATCTTGGATTTTAAATGACAACTTAGCGAATAAGCATGCATAAAATCTCCTTCATGTTCATGACGTGTCATGTCATAATTATTAAGGTGTCGTAATGGTCTTATGAACATCCCCTTCAAGTTAAGTGTTACCCATCTGTCTTTCTAGCATGCTTTAATTTTTTTCTCAAAATTTTTGATTAATATCCATGTTTAGCCAGAGTGTTGTCTGCCCTGTGCCCAAGTATGTTTTTCTTTAAATCAAGGACAGACACTCAAGCAGAGATTGACCTGGTTTGTCGCATTGCAAAGGCTTCTGGGGCGTCCGCTGCAGTGCCATGTCATCATTGGTCCAGAGGTGGACGGGGCTCTCTTGAACTGGCACACGCTGTAAAGGAAGTTGCTGCTCAGGGAAGCCGTTTTCAGTTCCTGTATAACTTGCAGG[T/C]GAGAACAGACGCAAGTAGTTACAGTGTAGAAGAAAACAAACAAAATGATCTCGTGTAAACCAAATTTAATCTAAGACCAGGCCAGGCAGACTCAGAGTGATGAATTAAACATGATTGTATCTGAAAGGGAGTCTTCTATAATGTGCTAATGGTTTTTTCCCTCCAGTCTGAGCATGTCAGGTTTAAGGAGGGTCTGTGGAGGCATCAGCTGGTTTGAGTTAACCTTAGTGAGTTTGGAGGTTGTGACATTGATTAAACAATGCTATGAAAGGAGCTGTAATCTCTGCCCTTGGCTCTGGCTGGTCTCTATTATCCTATTAGAGGTCTGAACACTTGCTATCCCAATCATCTGCCCAGAGAAATGACTGGGGTGATTTTATGGCCATCAGATTGGCGGAAGCTTCAATTCAGAACTGATAATGAGGTTAAAGTGTTTTTAAATTCTTCCCGCTTTTATCTGCATGCCTTTTATTTCAAGGAATTAGCGTGTCCTGTGCTCT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa915
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000147154 | Nonsense | 103 | 122 | 4 | 5 |
The following transcripts of ENSDARG00000091891 do not overlap with this mutation:
The following genes are also affected by this mutation:
Genomic Location (Zv9):
Chromosome 20 (position 26510614)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 20 | 26581917 |
| GRCz11 | 20 | 26481007 |
KASP Assay ID:
554-0821.1 (used for ordering genotyping assays)
KASP Sequence:
TCTTCTTTTCTCTTGTCTTTCAGATGAGCACTATGCCAGGCTTGCCTACA[C/T]GACCCTGTTTCTATGACATTGACCTTGATCCTGTGACCGAGGAGATAAAA
Long Flanking Sequence:
GGGAAAACATAATGAATGCAGACTGCCTTAATGACAGATCATCTTACACCGTTGTATTTTAAAAATAAAACATTCGTTTTAAGAAAGAGCACTCATTGGATGATTTGGGTTTGGCTTTTCTGGCTCCAGCGTTAATTTCTGTTTACAGTTTAGATTTGTCTGACAGTGAAGTCCTTTGGTTTTAACAAGATTTGCCTAGAAAAGACATTTTGCAAGAAAATTTCTTCAACATACTTCAGCATCTTTGAAACAACTTCTTGTTTTAGACTGAATTTATGATCCTTCCTACTAAGTGAATCTAAACCTGAGTTCCCTTGTGACTCCATTACACTGTTTCCTCTGATGTTTTGTGGGCATACAATATATTTGCCTTTTTGTTTTGATACCTGTGTCAAATAAAACTGAGCACTGATTCTGTTTTGTGCTATGTATACACTTTAGGTACTCCCTTCTTCTTTTCTCTTGTCTTTCAGATGAGCACTATGCCAGGCTTGCCTACA[C/T]GACCCTGTTTCTATGACATTGACCTTGATCCTGTGACCGAGGAGATAAAAGGCCTTTTCTGAGGACACACTCTTCACCAGTGCGAACTCAACTAGGTCTTAATTCACACTGCAAACATTTGTGCTGAGTTACAATGTTTCGATTGGCTTTACTTAGTATTTCGTTAAACTATGTAAAATTTCTAATTCTGTTCTATTGAGTCTGCAGACTGAGGTTGTATTACAAAACATGAAGTTTATATGATTAAAGGAATAGTTCACTTCTAATGACTGGTAACCATTGAGTTCCACTTAAGTTCCAGTTGAGGCTCTCCATTGACTTCCATAGTATTTAGTTTTGATGGCATCAATTTTAAAGACATCTTTTGTGATTAACATTAGAAAGAAACTCATACAAGTTTGAAACAAGTTGGGAGTGAGTACATGAAGTGAACTACTCCTTTAAGGATCACGTATGAGTCAAATTTTTTTTTTCATTTGGTAAAAAAGTGACACATGACA
Associated Phenotype:
Not determined