ZMP
A8WIP4_DANRE
Ensembl ID:
Description:
Novel protein similar to vertebrate interleukin-1 receptor-associated kinase 1 (IRAK1) [Source:UniPr
Human Orthologue:
IRAK1
Human Description:
interleukin-1 receptor-associated kinase 1 [Source:HGNC Symbol;Acc:6112]
Mouse Orthologue:
Irak1
Mouse Description:
interleukin-1 receptor-associated kinase 1 Gene [Source:MGI Symbol;Acc:MGI:107420]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa15573 | Essential Splice Site | Available for shipment | Available now |
| sa41119 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa21195 | Nonsense | Available for shipment | Available now |
| sa34296 | Essential Splice Site, Missense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa15573
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000101527 | Essential Splice Site | 29 | 685 | None | 18 |
| ENSDART00000137975 | None | None | 553 | None | 11 |
The following genes are also affected by this mutation:
Genomic Location (Zv9):
Chromosome 8 (position 8140035)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 7584672 |
| GRCz11 | 8 | 7603403 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCACTCGGGTTATGGACTCRCTTTCAAACTCAGACKGGATATCWTTCGG[T/C]AAGATTCATGGCKTTGTGTTTGTTTTTGTATCACAATKGTGCTGTGTTCA
Long Flanking Sequence:
AATGTGAAAAAGGAAATGGAAAATGTGAGTAATTTAGACGTGATGGCGAAGGAATTTACGAGCTCTTCTACTATGGCGAAGGGGAGTATTATGAATATTAATAAACGTAATATGATGTAGGTCTGACGTTAGTAAGTAGGCGGTGCTCATGTGTAATGTCTTTGCGCTACCTCATGAATAGTAATTAGTTAACAAGCATGAATATTCATGAACCAGGCATTTCGCCATTGTGATTTGTTTGTGACTCAAAAGAAGAAAGCGACCACCGAAAAGTAGCAGCCACAAGCAGGAAAAACCCCCGCAAGAACCACGTAAAAATAATATCTAAAAGTCTTATACACTAAAGGAGAAGAGAAAAGTTAGTGAAAACGCGGAGGGTTTGGGAAAATGTCAGGAACAGAGTTTGACAAGGTGTTACTGTACAATTTATCCGCGTCTGTTATGAATGACTTCACTCGGGTTATGGACTCGCTTTCAAACTCAGACTGGATATCTTTCGG[T/C]AAGATTCATGGCTTTGTGTTTGTTTTTGTATCACAATGGTGCTGTGTTCATTTATTTAAAGTTTAACCTAACTCCAGTGGATATGTTGATTAGCACACTTGCTAACATCAACTGTAAACTCGCTTAACGTTAGCCATCTCTTCGCTTAGCTTAGTCGAAAGGTGAAATATTTTCTTTTTAAAGCGAATGTTTATTTAAAGTGCAGATTAGTGTTGATTTATTTGCCCTGGTCTGGTTAATAGTTAGTTTGATAGTTTTTAGTAATTCGTAATAGTTTTTTATGTGTCAGTGTGGGTATTGTTTTGTATTCATAAGTTACTTTTATTATTATTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGGAAATTACACCTTTAATTGAGTTTGTTTTATGACTTAAATAATTTCAACTTTGATTTATCATGTTATTAGTCAGATCTCAGCATCTAACCTGAATGAATGAACACAACAAGAATATAC
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa41119
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000101527 | Nonsense | 71 | 685 | 2 | 18 |
| ENSDART00000137975 | None | None | 553 | None | 11 |
The following genes are also affected by this mutation:
Genomic Location (Zv9):
Chromosome 8 (position 8132605)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 7577242 |
| GRCz11 | 8 | 7595973 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAATTGGGGTTGTCGCAATGGGACAGTTGGAGCACTGCTGAAGATTCTT[G/T]AGGGACTCCAGTGGTTCAGAGCTCGTGATATCATTCTCAAAGCACAACTA
Long Flanking Sequence:
ATGGGGAGAACATGCAAACTCCACTCCGAAATGCCAACTGATCCAGCCAGAACTCGAACCAGTGACCTTCTTGCTGTGAGGCGACAGTGCTACCACTGAGCCACCATGACACCCGTTATATTAATCAGATGATGTCCTTTCACAGCTGTCTTGCTGCCAGTCAATCGTTGTTTTGTTGATCATGATTTTGAGGATAAATAATAAATGAAGTCCTTCACAACAAGAACGCAGTAATCTCAGATCAGTTCATCCAGATATTTTAATCTGAACTTGTTTGAAGAACTAAATTAGCTATTCAGTTTTGGATAGAATTCCCATTCAATTTCATAACACTCTCATTTTGCTTGCCAATTAAAGTATTTTATGTCCTTGCAGCTTCACAAATCATATCAGATCAGACTGAACTACGCCTTTTGGAGCAAAGCCCTCGACGGACGAGTAACCTCATGCACAATTGGGGTTGTCGCAATGGGACAGTTGGAGCACTGCTGAAGATTCTT[G/T]AGGGACTCCAGTGGTTCAGAGCTCGTGATATCATTCTCAAAGCACAACTATGTAGGTTTTTTTTCTTCTTCCTTTTTTTGATTTTTTTACCACATCTATGTGCCAAGCAGGTTATCAGTTGGGTTTTGTGGTTATCACGTTACTCGCTTTATAATCTAAAGTTTCACATTCCATGGTTCAAGAAAGAACTATGCTGTCAGTCAGATGTGAAATTTCTCAGTTGTGCTTATATTTCCCACGTTCTTATTTGGTTTACTTGTTTACTGCTTGTGATCCGTCAATGTATATTTTAAAACCTGTTTGTTGTTAACTTTCATCAAAATGAATTGACTTGTTCTGCCTGTAAATCTGAACTCAAATCTGTAGAAAGGCATTTCAGCAATCAATACTGATACCTATATTATGAAAATAAATATACTAACAGTATATGTATTTATACACTGGCTTGTCACATCAATTAAAAAAATGTAGATTTTTAAATCCATATTCACTGATTAAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa21195
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000101527 | Nonsense | 261 | 685 | 11 | 18 |
| ENSDART00000137975 | Nonsense | 140 | 553 | 5 | 11 |
Genomic Location (Zv9):
Chromosome 8 (position 8126516)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 7571153 |
| GRCz11 | 8 | 7589884 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCACAGGTACAGACATCCCAACATTATGGACTTTGTTGGCTACTGTATTT[C/A]AGGACAAACTTACTGTGTCATATATGTTTATATGCCCAACGGCTCTTTAG
Long Flanking Sequence:
AGGACGGAAGTGGACAAACTCTCTCAGTAAGAAGCTCTGCCTGTCCGTCTGTCGCTCCTGTGGCTCTTGCTTCCTTCTCTTGTGCTTTTAAATCTGAAGTCTTTCCTGTTTTCTCTTGATCAGCTTTTTGTAAGCTTGGCTGAGATTCATTTCTGTTTGTTCAACAGACTCGCAGAAAGGGATTTCCCCGCTTGAAATTTTGATTACTCTTTATGCACATCACCACACCTCTTCATGACCCAAAAAATGAGTCTCCAGCCCACTCTTCAAAACTTTTTCTGTGGTTAGTTTGAATCTTTTTGTCATCTTAGTGGGTCATTTGTTTCCCCTGACACTTCAGCCAACACTTTCAAGCCTTGCTTTCCTCAGCTATTGTAAAGCCTAAATGTTTAGAATAATTTATAATTAATAGTTTGACACTTTTTTTTTTTAATTACTCCCTGTTTTATTCCACAGGTACAGACATCCCAACATTATGGACTTTGTTGGCTACTGTATTT[C/A]AGGACAAACTTACTGTGTCATATATGTTTATATGCCCAACGGCTCTTTAGATGACCGGCTGCGCAATGAGGTAATTTGCATTTCCATTCATTCGTTTTCCTTCGGCTTAGTCTCTAATTCAGAGGTCGCCACAACGGATTGAACCACCAACTATTCCAGCATATGTTTTACATGGCGGATAAACCGCCAATCACAACCCACTACTGGGAATTACCCATACACTCTCGCATTCACACACACTATGGCCATTTTAGTTTATTCAGTTCACCTAGAGCACATGTCTTCGGACTGTGGGGAACACCAGAGTAGAGGTCTGCGCAGGACAGATTTTTAAGTTTTGCTCCTGCCCGCACCCGCAATGTTTTATTCCACACCTGACCGCTCCTGCTGTATATTCAGCCTTTGTTCACCTGCTGCCCACTTAGAATCATTTTCTGCCCAACCGTTCCCACTAAATTTAGATCTGGTTTCCAAAATCTCCTGTTTAAATCGGGTACTAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34296
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site, Missense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000101527 | Essential Splice Site | 632 | 685 | None | 18 |
| ENSDART00000137975 | Missense | 518 | 553 | 11 | 11 |
Genomic Location (Zv9):
Chromosome 8 (position 8111231)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 7555868 |
| GRCz11 | 8 | 7574599 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCCTCTCTAATTCTCATCTTAATATTATTATCCACAGGTTTTTCTGGAC[A/T]GAATGTTATCATCAACCCCGCTAGGCAGCGATTGGTACAGAAAATGGAGC
Long Flanking Sequence:
CAGTTGATTTTGAATGAATCGAGTGAGGCAGTGATTCAATGATTCATTCACAAAGACTGTCAACATTGTTCTAAGTGAATCAGCTATTTTGAAAGAAGTGTTTAAATAATTGATGCAGTGAATCAAACCTCTCAAAGTAATATTATTCATTCAAATAATAGTTTGAATGAATGGTTCAGTGCTTTGAATCAATCTACATTGTAAAAATCGCAATAGAAATAAAGATGAATGGAATCACTCATAAAGACAGTGACTTGCCTATAGCTTAAGTTGGTTTTAGTGTCACATTTATCCAAGAAAGGCCTGGCACAAAACACCCTTGGCTAAATATTTTATCATAATTATCAAATCAAAAAAAGTGCCTTATGTTTAACAAGGCTGCAAATATTTATACTTTAAAAATTCTTTATTATTCCACAAAAGTGTTGATGTCTTTTACTATTTGCTTTGTTCCTCTCTAATTCTCATCTTAATATTATTATCCACAGGTTTTTCTGGAC[A/T]GAATGTTATCATCAACCCCGCTAGGCAGCGATTGGTACAGAAAATGGAGCTTTATGAAGAAGGGAGGATTTTAACTTCTGATTTGTTGTCGTCAGGCGCCTCACTATGTAAGTGCTGAAACTGACAGTCAGATGACATTACTGCTGTTATGGGGGACAGTTTTTTTTAAGAGTTTTTATGGGAATACGAGTCATTTTCAGCTCAGTTATCATGATTGCTTCTGTTTAGGTAACATCTGATTGGCCTGTGGCAAATGTTTGTAGCTTTTTAGGCATCGCACAAGTCAGAGATACCAGGGGTCTGTTTTTTCGTAGCTGGATTACTCAGTTAGCTGGATTTGGTTATTGACGATTTGACATGATCCAGGATCGTTTAGTTCTTCAAAACTCATGCGAGAGTTGTTGTCATGGCAACAGTTCTGGTAGCTCAAACCTGCTCTGAAGCAGGTTTATTTCATACAAAAAGGATTAGATTGGGTCAGTTCAAGCAAAGATAATACT
Associated Phenotype:
Not determined