Busch Lab

ZMP

myo1bl2

Ensembl ID:
ENSDARG00000024694
ZFIN ID:
ZDB-GENE-030131-695
Description:
Myo1bl2 protein [Source:UniProtKB/TrEMBL;Acc:B5DDQ9]
Human Orthologue:
MYO1B
Human Description:
myosin IB [Source:HGNC Symbol;Acc:7596]
Mouse Orthologue:
Myo1b
Mouse Description:
myosin IB Gene [Source:MGI Symbol;Acc:MGI:107752]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa14798 Essential Splice Site Available for shipment Available now
sa34595 Nonsense Mutation detected in F1 DNA Not yet available
sa34596 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa14798
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000037459 Essential Splice Site 137 1081 None 29
ENSDART00000077187 None None 251 None 10
ENSDART00000138204 None None 855 None 21
ENSDART00000142974 None None 142 None 5

The following transcripts of ENSDARG00000024694 do not overlap with this mutation:

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 16411507)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 16232145
GRCz11 9 16169411
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTTACCCYTGTCTTAYTGTTACTGTTAAACTCTAMTTGTAATTGTATTTC[A/T]GAAAAACTGAAGCTGGACCGGGACTTCAGCAAATATAACTACCTTAGCCT
Long Flanking Sequence:
GGTTTAACTGCATTGCTTTATTAATACGTTCTTGTAATGGGATTAGACATATATTCTGTACCTATGCTGCTTGAGCTTCAAATGCTTTTTGCTTAATATCTTGATAAGTTGTGATGGGTGTTTCTTTTTCAACTCACCCTGCATTCAGTAGACCAATCACGACTCGGGAGGCCATCAGACCATTACCATAATTTAGCATCACAGAAAGGAGGGGTTTTGTAAAATAAACCATTGAACAAATCATATAAGAGTTGTGGAGATAATTAAGTAAAAAATAAATGCCTATTATAAGACAATGAAAGTGTTTTTGAACTTGCATGCATATCGGCCTGTTGTTGGGGACTTCCCAAACCAAACTATGATCTTTTATAATGCATAATAGGGACACTTTAGTAATAGGCAGGCAATATGCCAGAAGTTAATAGTCTGAATTGTGACTTAAACTAAAGTGTTACCCTTGTCTTATTGTTACTGTTAAACTCTACTTGTAATTGTATTTC[A/T]GAAAAACTGAAGCTGGACCGGGACTTCAGCAAATATAACTACCTTAGCCTGGATTCAGCCACTGTCAATGGACTGGATGATGCTGCTAGTTTCAGAACTGTCAGAGTAAGTTTGTAAATTTTACTTTTAGCCTTGCCATGCGGTACCTGACTCTTGGGATAAGCTCAGGCAAAGACAGATATACAGTACAAAGACAGTTCACTCACATTACTATGAATTGGGAAAATGTGATGTTCACTATGGATGCCACATCGAAGGAAGACCCTTTTTGGGTCAGAATAGCCAGTGATTCTGTGAGGTAGGGGCCTGTACACATTTGCTTGTTTGTTATGGGAAGCATTGTCATTTGGCAACTACCTAATGCCTGTGTTGATTTTGACAGGAGAAAAGACATCACAGCACATCCCAAAACATATTAAGCCCTATCATACAACCGGTGCAATGTGGCGCAAAGCATGAAGCAATTTTTATTTGGTACTTTCAGCTCGGCGCAAGAGTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34595
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000037459 Nonsense 631 1081 17 29
ENSDART00000077187 None None 251 None 10
ENSDART00000138204 Nonsense 460 855 11 21
ENSDART00000142974 Nonsense 24 142 1 5

The following transcripts of ENSDARG00000024694 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 16446644)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 16203525
GRCz11 9 16140791
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGAGGAGACAGTGCCTTGAGGACTTGGCAGCACTCATCCAGAAGATCTA[C/A]CGTGGCTGGAAATGTCGCACTCACTTTCTCCTTCTGAAAAAGAGCCAGGT
Long Flanking Sequence:
AAAACCCTTTTGTATGTGGAACTACTTTCTTCTACATTGGATTCAAATCATAAGCTGACAGTTAAAACAGTTGAGCAAGCATCTTTTGAACTTTAGATCTGTAGTGTCTGCTTTTTGCTGGCTGTATGTGGGCAGAGTAATACACAAAGGGTAAAAAGGCTGTAGGAGTTCTGATATTGCAGAATATCGCACGGCTATCAGCCAATCAGATTTGAGAACCAGACAGAACTGTTGTATATACACTCACACACACACACACACACACACACACACACACACACACACACACACACACACACACATATATATGTGTGTGTGTGTGTGTGTGTGTGTATATGTATGTATGTATATATATGTATATGTGTGTGTGTGTATATGTGTATATATAATTTTTTATTTTTTTTATGCTAATTTGAAAGCTTTTTTCTTCAGCTCTTTTTTTTGGAAGAGAAGAGGAGACAGTGCCTTGAGGACTTGGCAGCACTCATCCAGAAGATCTA[C/A]CGTGGCTGGAAATGTCGCACTCACTTTCTCCTTCTGAAAAAGAGCCAGGTGGTTGTGGCAGCCTGGTACCGAAGATTTGCGGTGAGCTGCATTTATATCACCTTCTATAGGAACCATTTAGAGAGAGACATTTTTTTAATTGCAAGATGGTGACTTAAGATGTTTTTTTTTTATTGTTTTTGTTTTTTAAATGCAGCAACAAAAGAAGTACCAGAAAATCAGGTGTTCTGCCTTAGTAGTTCAATCTTTCATTCGTGGATGGAAGGTAGGTTTCATATTCTGCAGTTTCCAAAAACAAACAAAAGGTCTTTTCTCATTCAAGTTTTTTTATAGGCCCGGAAGCTTTTGCGTGAACTAAAACACAAGAAGCGATGCGAAGAGGCTGTCACAACAATTTCAGCTTATTGGCATGGAACCCAGGTAATGAACACAGTTTCTCATTCTGTAAAGTGATGAAAACTTTTACTGTGGGGTTTGATTTTCAACATTAGAGCTTCTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34596
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000037459 Nonsense 807 1081 23 29
ENSDART00000077187 None None 251 4 10
ENSDART00000138204 Nonsense 578 855 15 21
ENSDART00000142974 None None 142 None 5

The following transcripts of ENSDARG00000024694 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 9 (position 16453686)
Other Location(s):
Assembly Chromosome Position
GRCz10 9 16196483
GRCz11 9 16133749
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATAACTGAACAATTGTTTTACAGGTTCGTCGGGAGTACAGGAAGTTCTTC[A/T]GAGCTAATGCTGGCAAGAAGATCTATGACTTCACCATCCAGAGAATTGTA
Long Flanking Sequence:
AGCAATTCAATGAGACATCTACTTATTGTTTTTATTCTAATAGCTGATTATTTCAGCAAATGAAGTAAATAATTCTTTGAATAACCTAAATAAATGGATATTAGGATTTCGCCCCAATGTGTAAGGGTTTCTATTTGCCTAAAATACCCTTGTTTTCTGTTTGTTTTTAGGTGTCTGTCCTGTCTGATGTCTGCATGCTGCTACTAACATACTCTTGGCTTTCACAGGCATTTGTTTTTTTCTCCGCCCTCCCATAATGTTTTACTGTTTCTTTTTTTGTGTGTATATCTTTGTATAAGCATCTTACGGGTGATCTCCATCTTTTCTGGAAAAGATAATTGAGTACAGATGTACTATATGACTGTAGAAGGTGGTTTTGATCACATTACTGTTTCTGTTCTGCCCGCTTCCAACTTTCATCACAAACTTTTGCAGCACATAGAAGAGAGCATAACTGAACAATTGTTTTACAGGTTCGTCGGGAGTACAGGAAGTTCTTC[A/T]GAGCTAATGCTGGCAAGAAGATCTATGACTTCACCATCCAGAGAATTGTAAGTCACTTAAGAAGTTAATTATTGAATACAGTTTTATAATCCAGAAAGAAGACTTACTTGTTGGTAGGTCAATATTTATCTTCTAATTTACAAAAGTTTCTGACAAGTCCAGTTTTAATAGGGAGCATGGTTTGCTTAAACTATTTAAAACAAAGTGTTTCTGCTTCACTTTTTCTATTTTTTATTCTAGGTAGATAAGGTAAAATCCCCTCTGCTAAATCCATAGAAGTGTAGATTACTTTTTCCATGTAATCTTTATGTGGCTTACAAAGTACATTAAATAAACAACTAATTGGTGCTACCTTTTGGAAATGTATTACCTACACTTAGTCACCTGAGAAGAAAGAAAATGATTTAATAAAAGACTGGATCCAATAAAAGATCCAATGAAAGTTCCGAGCTCCTGTTTTGTCTACAGATACAGAAGTACTACCTAGGCTTGAAGAAGAC
Associated Phenotype:
Not determined