Busch Lab

ZMP

mical3

Ensembl ID:
ENSDARG00000021979
ZFIN ID:
ZDB-GENE-050126-2
Description:
Novel protein similar to vertebrate flavoprotein oxidoreductase MICAL3 (MICAL3) [Source:UniProtKB/Tr
Human Orthologues:
MICAL3, MICAL3
Human Descriptions:
microtubule associated monoxygenase, calponin and LIM domain containing 3 [Source:HGNC Symbol;Acc:24
microtubule associated monoxygenase, calponin and LIM domain containing 3 [Source:HGNC Symbol;Acc:24
Mouse Orthologues:
Mical3, Mical3
Mouse Descriptions:
microtubule associated monoxygenase, calponin and LIM domain containing 3 Gene [Source:MGI Symbol;Ac
microtubule associated monoxygenase, calponin and LIM domain containing 3 Gene [Source:MGI Symbol;Ac

Alleles

There are 8 alleles of this gene:

Allele Name Consequence Status Availability
sa36582 Nonsense Mutation detected in F1 DNA Not yet available
sa36583 Nonsense Available for shipment Available now
sa16748 Nonsense Available for shipment Available now
sa36584 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa44883 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa36582
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014496 None None 196 None 5
ENSDART00000028938 Nonsense 691 1011 15 21
ENSDART00000101026 Nonsense 691 2269 14 40
ENSDART00000101035 None None 255 None 15
Genomic Location (Zv9):
Chromosome 18 (position 10295622)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 10878868
GRCz11 18 10847586
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATAAAAAAGAAAAGGAGCTGGATGGACTAGGGAAAAGACGAAAGACGAGC[C/T]AGGCTGGACAATCGGAGGACGTAAGGCCATATCATGCTGGATCACTGGTC
Long Flanking Sequence:
TTTTGGTAACGGTTAAGTTGCACTTGTTAACATAATAAAGATGAATAAATAATACCATAATAAATGTATTACTAATTGTTTGTTCGCGTTAGTAAAAACATTAACTAATGGATTATTTTTTTAAAGTGTTACCATCCTTTCTTTGTTAAATAGCACTTGGTAACTCTTTCAAAAAGACAAAAAAGAAAGGATAATTTTGTCTTCAACTATACATATCGAGCCTATTTTTTGTGTGTTGTTTTAGAAAACCAGAATCTGAGCCCTGAGGAGAAGGCCGCACTGATCGCCAGCACTAAATCACCCATCTCATTCCTTAGTAAGCTAGGTCAAAGCATCGCAATCTCCCGCAAAAGAAACCCCAAGGTACTCAATTATCTTTTCGAAGCTGCAAAAACTGAGTCAAGCCTTTCAGTCTCAGCATTCAACATTTCTTCTTAAATGTCATGCAGGATAAAAAAGAAAAGGAGCTGGATGGACTAGGGAAAAGACGAAAGACGAGC[C/T]AGGCTGGACAATCGGAGGACGTAAGGCCATATCATGCTGGATCACTGGTCCAACATAATGATTCTATGTTTGTAGTTGTCTAAATGGTTTCTCTGCTGTTCTCTTATCTCAGGAGGAGCTGCAGAGGGCTAATCGAGACGACAGGCCATCTATAGCCACAGCTCTGGCAGAACGTAAGATCGACTCCGCTGCAGCAGCCAACAATAACAACAAAGTGAAGTCGATGGCCACGCAGCTGCTGGCCAAGTTTGAGGAGAACGCGCCGACACAGTCCACTGGGCTCAAACGACAGGTGGGCTGACCTTTGTGTTTGCGCAGTTGCTGCTTAAAATGACTTTGGATACTTTCAGCTAGAATTCTTAAAGCGACAAGTGCAATATAATATAACAACTTGCCTTACCAGGCCAAACTGATTGTTTGAATATTTGTGAGCATAATATCTACAAAATATTTGTTCCTCCTAACAATAATAATTTGTGTTGGTCAAAGAGTAATCACAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36583
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014496 None None 196 None 5
ENSDART00000028938 Nonsense 909 1011 20 21
ENSDART00000101026 Nonsense 1184 2269 27 40
ENSDART00000101035 None None 255 None 15
Genomic Location (Zv9):
Chromosome 18 (position 10325511)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 10908757
GRCz11 18 10877475
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGGCCAAACGTCTGAAAGGGACTCCGGAAAGGATCGAGCTGGAGAACTA[T/A]CGTTTGTCAATGATGAGGGAGGAGGAGCTGGAGGAGGTGCCGGAGGAGAC
Long Flanking Sequence:
TTAATATTGAGGTGTTTTTTTTCCAGAAAACAAGATATAATTTTTTATGCTATTTCATTTTTCTAGTATGTTTCTTGATTTATAAATATTTAGATATTTGGAATAAAAACAGGACAAAACTACTTAGTTTATTATTATTATTATTATTATAACCGCTCAGGGATGAGCTTTTTTTAATAAATGGTTGGAAATGAATGCTTTTCTTTTTTTTTATCTGATTCATCGATTAATCGAAAAAATAATCAACAGATTAATTGATTAATAAAATAATCGTTAGTTGCAGTCCTAAACTAAACCATGAACTTTTAAGAAGTTATTATTAATATTAGCAACATGCTAATAATATGAAGCCCCTCCCTCTCTCCTGTTAACATCTAATGTTCACATTAATGACGTTCTGTTTTCTCGTCCCCCACAGAAACTGAGGTAAATGGTGTCACGGAGCCCAGCGTGGCCAAACGTCTGAAAGGGACTCCGGAAAGGATCGAGCTGGAGAACTA[T/A]CGTTTGTCAATGATGAGGGAGGAGGAGCTGGAGGAGGTGCCGGAGGAGACATTGGCGGAGCACAACCTCAGCAGTGTGCTGGATAAAGCCACCGACATCGAGGAGGGATCCAGGTATCGCCCTCATCTCTAATAATGCAAGCCCATTACCGTATATAATACAGTGCAAATTAAAAGTGCTTGTTCATTAGTGGTGCTTGGTGGTTAATATACAGTTGAAGTCAGAATTATTAGCCCCCCTGAATTATTAGCACCCCTGCTTATTTTTTTCTCCAATTTCTGTTTATAAGAAATAAGTAATATTTAATATAATATTTAATATTTAATAATAGATTTTATTTTCAGGACACTTCTATACAGCTTAAAGTGACATTTAAAGCCTTAACTAGGTTAGATGTTTTTTTCTTTAAATAGGCACTAATTTGCACACATTTATTGACCTAAAATCCAAACATGGTATGAAGTTGGTTTCAAAATTTATGGTTATTTTTATTAATTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16748
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014496 None None 196 None 5
ENSDART00000028938 None None 1011 None 21
ENSDART00000101026 Nonsense 1563 2269 32 40
ENSDART00000101035 None None 255 None 15

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 10337209)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 10920455
GRCz11 18 10889173
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GGTTGAAGAGTGCAGAGATTAGAAAAAGTTTAGGGCTYACTCCCCTGGAA[C/T]GAAGCAAAACTGYGGTGGAGAAGAGCATTGTGAAAACKCCAACACCCGAA
Long Flanking Sequence:
ATGAAGTTTCTCCTGTAGTACTAGTTAAATCTCCTGGTGCACGTTTCTTCCCTGAGCCCTATCTGCCTGATAAAGTCAAGCAGAACATTCCCCCGCCTCAGAGTCCTGATGTTAAAACCCCTCATTCTCCTGTAGCTCAAATCATTGCGCTGTCGCCCATCTGTTCCCAGCCTGTTCCACAACCAGGCACAGCATCTCCCAAATCTCCAGTCCAACCACAGCCTTGTGCCTGTTCTCCAACAGGCAATCCTTTGTCTCCGATTTGTACCCAATCGCAACCCTGCAATGAGCCACCTTCACCCCTATCCACAAGCTCCCCCGTCAGGACTCAACCAGTCCCAGCAGTAACTTCTACTCCTTTAGCTAAACCTGCTTCCGAGAATAGGACTAATGAACATTTGAAAGATTCAACTCCTGAGCTTAAGAAAACAGACCTCATTGAGGAGTTCTGGTTGAAGAGTGCAGAGATTAGAAAAAGTTTAGGGCTCACTCCCCTGGAA[C/T]GAAGCAAAACTGCGGTGGAGAAGAGCATTGTGAAAACTCCAACACCCGAATCATCATCTCCTAAGTCTTATACCCCAGAGGACTTGTCTGAGGAACAGAAGCCTACATTTACGGGCCGTTCTATCATACGCAGGATCAATATTACCTTGGAGGGTCAGGTTATATCTCCGGTGGAACCTAAAAGTAATGGTTCAGAAAAGAAGGACTTAAGCAGCAGTTCAGGGTTGGGTCTAAACGGAAGTGTGACCACCAGTCAGACAGCTGCTAGCGACAGCTACAACAACTCTGATTCTACAATGCTTACCCCTCCTTCCAGTCCACCACCTCCTCCACCCAGGGAGGAACCTGCTTGTCTCCAAAACAAGAAGTCTCAGGTTTCCTGGGACAACCTCCTTGAAGGCACAGAAGAACCCAAATCTGAGACCATGCCCATTAAGCCCAGGACTCCAGTTAGTCCCCCTCAACCAAAACAAAAACCAGTTACAGCTCCAGTGCCAACC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36584
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014496 None None 196 None 5
ENSDART00000028938 None None 1011 None 21
ENSDART00000101026 Essential Splice Site 2018 2269 None 40
ENSDART00000101035 None None 255 None 15

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 10338576)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 10921822
GRCz11 18 10890540
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACTGGAGACTCGGGGAAGAAGAAAGATTCACCCCTGGACAGGTCCTCAGG[T/C]CAGCTGGAAGTTTTTCATTTGAATGGCTCATCTTTTTTTCTAGCAGTCTT
Long Flanking Sequence:
GATGCAATGGCCAAGCAGCTTACAAAGATGAAAGATTCTGAGGTTGCCAAGGGGGCTGTAGCAAAAGTAGCCTGGGATATTCCTGAAACAAAAGGAAAAAGCAAAAAGCAATCTAAAGCCCAGAAGGACTCTGCAGTGAAGGCCTTGGAGTCCAAAAAGCAAGCAGACACACTTCCAGACCGTTTCTTCTCTACACCATCTAGTAAGGCCTTAGACAGCTCTGTCACATCTTCAGAGAGCTCCACAGGGGGCAAAAGCAAGAAACGCAGCTCACTGTTTTCTCCACGCAAAAACAAAAAAGAAAAGAAAGCCAAAAATGAAAGACTGTCCAGCACTGAAGAAACGCCGCCCAAGCACAAGTCCCTTTGGAAAGCAGTGTTCTCCGGCTACAAGAAGGACAAAAAGAAGAAAGATGACAAGTCATGCCCAAGTACACCCTCAAGCTCTACAACTGGAGACTCGGGGAAGAAGAAAGATTCACCCCTGGACAGGTCCTCAGG[T/C]CAGCTGGAAGTTTTTCATTTGAATGGCTCATCTTTTTTTCTAGCAGTCTTACAGAATTTATATAGTCCTACTCTGACACCATCCTAAGCATCATTAAACCTCTTAAATGACTGATTTAGATCAATTTGTGCAGTACATTTAATTTAGTTCGCTGTCAGTATACGATAATTTCCTCAAAAAGCAGCTCACTTCAGACCCTCATGGGTTTTGTTCTTGCAGAATTTTGCTGAAATTTAGTTTGACTTGCATTTTTTCTCAGTCTTTTTCCACTTACGCAAAGATCTGTTTAATTTACCGCTGTAGATTTACGTCTGAGGAGAAATCTAAGCTTTTCTGAGGACTCTGATCTCTCCTGTGACGATGTTCTGGAAAGATCCTCTCAGAAGTCCAAGGGTGATGTAAGTGTATATAATATTTAAAGAGTTTCTTCTTTCTGATTTCAGTCAAATGTTTTTTTTTTCTCTCTGCAGCTTAAACTTTAATGAAATCTTTTGCTCTTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44883
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000014496 None None 196 None 5
ENSDART00000028938 None None 1011 None 21
ENSDART00000101026 Nonsense 2228 2269 40 40
ENSDART00000101035 None None 255 None 15

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 18 (position 10369292)
Other Location(s):
Assembly Chromosome Position
GRCz10 18 10952538
GRCz11 18 10921256
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAGACAGAGGAGGAGCTGGCAGAGGAGAAGCAGATTCTGAATGAGATGT[T/A]GGAGGTGGTGGAGCAGCGAGACTCTCTGGTGGCCCTGCTGGAGGAACAGA
Long Flanking Sequence:
CCAAGCTCATGGGAGTCATACACAATATTCAATCTTTTTCCACTGCAGCATGACTTTATATTTTATACTGTACAGTATTTCTGTTAAGTGACAAGACTTTTGTTTAAGAAAATTCAGAGCTTACTGTCCTAATTAAATTATTAAAAATCAAGGCATGATCATATTTTATTTTGGTAAAATAAGCCTAATCTAGAGGCCTTTGTTTTTTATATAAGACACTTCTGATACCAAATGATCAACTAGAAGTCAAGTTATTATTTGTTGTTTCTAAAACTTGCATAGGTGACAAGACTTTTGTCAGGCAGTGTACATAGCGGCTATAGCAAAACACACATTTTTTTTTTACAACAAACAATCCAACAGGAAAAAGAAACGACTGTTGTATTTCATGATGTATGGCCGTTTTGTCTTTTAAAAGAAGCTAAAATCCCCCCTGTCTGCAGATCATCTGAAGACAGAGGAGGAGCTGGCAGAGGAGAAGCAGATTCTGAATGAGATGT[T/A]GGAGGTGGTGGAGCAGCGAGACTCTCTGGTGGCCCTGCTGGAGGAACAGAGACTCAGGGAGAAGGAAGAAGATAAAGACCTGGAGGCGGTGATGCTCTCCAAAGGATTCAACCTCAACTGGGCTTAACATAACAATGTCCAAAAACCATCTAACCCGCCAGCGCTTCACTACAGGGAGTACAAAAAAAAATCTAAATCTCAGAAAGAGTCGCTCTTGGTTTTATTGGGCATGTCAACAACGTTTACAAACCTATTCATGAGCTCGATGGTGATGTTTTTATGAGGTTTCCTGGCACGACTCAGGGCGTTTTGTCCAATCGGCAGCCAAGGCAAGGCGTTCTCCATTTCGGAAATAAGGAGAACATAAATTTTTATTTAGTAATTTCTGGGACATATCAATCAATCCTGCTGATGTTGAGGAAGTCTGAGACTAAATGACTCTACATATAAAGCCAGTCTTGTTTATCAGAGAATGTCTGGTCAATCAACTGTTACGTTTT
Associated Phenotype:
Not determined