Busch Lab

ZMP

ntrk2a

Ensembl ID:
ENSDARG00000095706
ZFIN ID:
ZDB-GENE-010126-1
Human Orthologue:
NTRK2
Human Description:
neurotrophic tyrosine kinase, receptor, type 2 [Source:HGNC Symbol;Acc:8032]
Mouse Orthologue:
Ntrk2
Mouse Description:
neurotrophic tyrosine kinase, receptor, type 2 Gene [Source:MGI Symbol;Acc:MGI:97384]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa12452 Essential Splice Site Available for shipment Available now
sa30907 Nonsense Mutation detected in F1 DNA Not yet available
sa41298 Nonsense Mutation detected in F1 DNA Not yet available
sa34500 Nonsense Available for shipment Available now
sa27277 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa12452
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000140277 Essential Splice Site 64 375 None 8

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 52039792)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49790179
GRCz11 8 49778948
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTTCCCCAAGCTGGAGTCCGAGGCGGACATGGAGAACGTCACTGACATG[T/A]AAGTCATGCTGGGGGTCATATACACTGAAACAAAAGCGATACATTGGATT
Long Flanking Sequence:
TGATACACTATAAAGAAAGCCTTGATCAGTGTAAGGATGTTGTCAGGCGGTCAATAACGCGTGTGAGTGAGTGAAGGATTGATTGATGTGTCCTGCTGGTCTCCTCCCCTCAGACGCGCGCATCATCCAGCGCGTCTCCAGAGCGCGTCTTCAGTCCGCATCCGAGCGTCATTCAGCGCAGCATCTCGGGCATTCGTTCTGTAGGAATATACGGTCACTCGCTGTTGCTTTTTCTGCTCCGGCTCTGCGCGTCTCCAGACTCCGGGTTTTTTTCGGGGGTCGTTAAATCTGGAGGTGAGGACCCGGGGATGAGCTTCGGCATGACGGGCTGCGGGTTCGGTTGGGCGGTGATGCTGCTCGCGCTCTGGAGGCCCGCGACCGCTTGTCCGGAGCTCTGCACGTGCACGGGTTTGCGGATCTCCTGCGTGGACGCGGAGCGCAGTATTATGGCTTTCCCCAAGCTGGAGTCCGAGGCGGACATGGAGAACGTCACTGACATG[T/A]AAGTCATGCTGGGGGTCATATACACTGAAACAAAAGCGATACATTGGATTTACTCCGGTTTTTTAACCGCGGTAAAGTTTGACATTCATTAGAAATTCGATTTCAAACCAATTAAATTATTTGCCCCTGCTATAGTTTGAGCCAAAAATATCTCAGATAGGTATAATTATGTGTCCTTTATGTTGCACAAGGCTTAATCGATAAAAAAGACCAATTAAACAATTCAACGAAATTATACAATAAAACCAGTAGCAAAATGTTCAGAAAAACACCCTGCTTATTGCACAAGACTCTGTTTTTTGCAATTAGCACTTTATTTATTTTATTATATTTTTAAAATAACTTTTAATGTAAAAATGGTAAAAGTTTTGTTTTTCACAGTTATGCCTTTGTTGATTTTATATACAGTACTGAATCCATATTTTCAGTAATTCGGATACACTGTAAACACTTAAATGAATTAAACACTGACACCATTTGAGATAAAAATATACAAATCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa30907
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000140277 Nonsense 267 375 7 8
ENSDART00000140277 Nonsense 267 375 7 8

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 52056607)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49806994
GRCz11 8 49795763
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAACAAATGCAGAATCACCTGCAGATCGGATAACATGGTGGGAGAATCC[G/T]AGGCCTCTGTGGAGCTGGACATATTGTGTAAGTTATCAAGAGACACAACA
Long Flanking Sequence:
GAAGATTAATAAATGAATATAATAGATGATAACAAACTAAATATGAACTTTTTAAAACCAATTTTAAGACTTTGATTAATGGAACAATGTAGAAACACCCTAAAGTCAATCTAAATTCCCATTTGCAAACCATTTTCGTAATGTGGCGTAACAGGATATTCTCAAAAACAACATTACTCTGTCAACATTATGCAGCTGGTCATCCGCCGAAATGACGCCAACAGTGATTTCATTTTGATTAAAAACATATTTTTTTCTCTCTTTGGAATAACGTGCAACCGTAACGAATCCTCCACAATATGCATTATGAAAGTAAATACGGTGGGGTGGGATTGCGTGTTGACTTTAAATAGAAATGACATTGGCCTTGCTGTAACTTACACTCGCAGGAGGAAGGCTCAGGTCAGATATCAAGGTCGCAGCTCAAACTGACGAACGTCTCCTCCCTGGACAACAAATGCAGAATCACCTGCAGATCGGATAACATGGTGGGAGAATCC[G/T]AGGCCTCTGTGGAGCTGGACATATTGTGTAAGTTATCAAGAGACACAACATAAGAACATTCTAGAGATCCACGCCTACTGGGGAGGGGGAACAATCCAAACCATTCCATTGACTTTGTATTGTGTGAAGGTGCCTACTTGTAATTTCTAACGAATGGAAAAAAAAGCAAACGATTTCTAAAAGTTGTTATGTGACAAAATATAAAGTTTAATGAGCGTTTAAAGACTTAAAAGTAGAGCAATCAGAGCAGAGTCATCTGACCAATCAGAGCACAGCCATCTGACCAATCAGATCAGAGCCATTTGACCAATCAGAGCAGAATCATTTAACCAATCAGAGCAGAGTCATCTGACAAATCAGAGCAATGTCATTTGACCAATCAGAGCACAGCCATCTGACTAATCAGAGCAATGTAATTTGACCAATCAGAGCAGAGTCATCTGACTAATCAGAGCAGAGTCACCTGACCAATCAGAGCACAGCTTTCTGACCAATCAGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41298
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000140277 Nonsense 267 375 7 8
ENSDART00000140277 Nonsense 267 375 7 8

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 52056607)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49806994
GRCz11 8 49795763
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAACAAATGCAGAATCACCTGCAGATCGGATAACATGGTGGGAGAATCC[G/T]AGGCCTCTGTGGAGCTGGACATATTGTGTAAGTTATCAAGAGACACAACA
Long Flanking Sequence:
GAAGATTAATAAATGAATATAATAGATGATAACAAACTAAATATGAACTTTTTAAAACCAATTTTAAGACTTTGATTAATGGAACAATGTAGAAACACCCTAAAGTCAATCTAAATTCCCATTTGCAAACCATTTTCGTAATGTGGCGTAACAGGATATTCTCAAAAACAACATTACTCTGTCAACATTATGCAGCTGGTCATCCGCCGAAATGACGCCAACAGTGATTTCATTTTGATTAAAAACATATTTTTTTCTCTCTTTGGAATAACGTGCAACCGTAACGAATCCTCCACAATATGCATTATGAAAGTAAATACGGTGGGGTGGGATTGCGTGTTGACTTTAAATAGAAATGACATTGGCCTTGCTGTAACTTACACTCGCAGGAGGAAGGCTCAGGTCAGATATCAAGGTCGCAGCTCAAACTGACGAACGTCTCCTCCCTGGACAACAAATGCAGAATCACCTGCAGATCGGATAACATGGTGGGAGAATCC[G/T]AGGCCTCTGTGGAGCTGGACATATTGTGTAAGTTATCAAGAGACACAACATAAGAACATTCTAGAGATCCACGCCTACTGGGGAGGGGGAACAATCCAAACCATTCCATTGACTTTGTATTGTGTGAAGGTGCCTACTTGTAATTTCTAACGAATGGAAAAAAAAGCAAACGATTTCTAAAAGTTGTTATGTGACAAAATATAAAGTTTAATGAGCGTTTAAAGACTTAAAAGTAGAGCAATCAGAGCAGAGTCATCTGACCAATCAGAGCACAGCCATCTGACCAATCAGATCAGAGCCATTTGACCAATCAGAGCAGAATCATTTAACCAATCAGAGCAGAGTCATCTGACAAATCAGAGCAATGTCATTTGACCAATCAGAGCACAGCCATCTGACTAATCAGAGCAATGTAATTTGACCAATCAGAGCAGAGTCATCTGACTAATCAGAGCAGAGTCACCTGACCAATCAGAGCACAGCTTTCTGACCAATCAGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34500
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000140277 Nonsense 357 375 8 8

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 52059439)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49809826
GRCz11 8 49798595
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAGTCCCACGCACATCAACAACGGCATGTACACGCTGCTGGCCAGAAAT[C/T]AATTCGGAGAGGACAGCAAGGCCGTATCTGCTCATTTCATGCATGAGCCA
Long Flanking Sequence:
CATGCTATGATGTTTTAATTCATAGAATAATGAATTGTTGGTCAATAAATAAAAGTAATCCTACTATTTCTGTCATGTCAACTCTCGAAATTGAGATTTAGAGTTGTAATAAATATGGTCTTGGTGACATAAAGCTGCTACACCGCTGCTGCTAATTCTTTAATAGTCAAATAATCCATTTTAGCAATACCATAATGCTACCATAAATAATGAAGTTACATCTGTGCTTGTTGATTCTTGTGTTATTTGGGATGCCAGTTCCACCTGTAATCAGCAAGCTGACAGATGCCATTCCGGACCACCACTGGTGTATTCCCTTCAGCGTGTCTGGCAACCCGAAACCCAAACTCAGATGGTTATTAGACGAGCAACCCATTCAAGAGGGCAAGTTCATCCATACCATGATCCACGATTACTCGGAGGGCGAATACCACGGTTGTCTACAGCTGGACAGTCCCACGCACATCAACAACGGCATGTACACGCTGCTGGCCAGAAAT[C/T]AATTCGGAGAGGACAGCAAGGCCGTATCTGCTCATTTCATGCATGAGCCATGGAACGGTGAGTTGAAATTAGCATGCATTCAAGTTAAAATTGTCAGGTTATACTTTTGCGTCGAGTGCATGGGGTAGATTCGATGGAGCGTTTGAGCAGTCACACACATTTCGCCGTATCCTGACGCGCACCCCTCAAAAAATAATGACAATATGTTTTGCCGACGTGGAGCGCAGGATCTGTCAGATTGGTAGTGGTCAGGGGCATCACTAGACCCCATTTATTAGGGCACGTGCCTCAGTAAAAATCGTCAGTGCCCTAATAAATGCTTTGAGATAAGATTGATATTTATTAGGAGTGGTAATCCCAAAATAAAGATGTCATTCATTATGCAACCCAACCAACGCTGATGAAAGCAATGTAGTGTGATCAAAAGGCAAACTGGGCATGCGCACAGAAAAAAAACCATACCCGCACGCCTCACACACCGCTCCTGCTGACTCACTGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa27277
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000140277 Nonsense 363 375 8 8

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 8 (position 52059457)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 49809844
GRCz11 8 49798613
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACAACGGCATGTACACGCTGCTGGCCAGAAATCAATTCGGAGAGGACAGC[A/T]AGGCCGTATCTGCTCATTTCATGCATGAGCCATGGAACGGTGAGTTGAAA
Long Flanking Sequence:
TTCATAGAATAATGAATTGTTGGTCAATAAATAAAAGTAATCCTACTATTTCTGTCATGTCAACTCTCGAAATTGAGATTTAGAGTTGTAATAAATATGGTCTTGGTGACATAAAGCTGCTACACCGCTGCTGCTAATTCTTTAATAGTCAAATAATCCATTTTAGCAATACCATAATGCTACCATAAATAATGAAGTTACATCTGTGCTTGTTGATTCTTGTGTTATTTGGGATGCCAGTTCCACCTGTAATCAGCAAGCTGACAGATGCCATTCCGGACCACCACTGGTGTATTCCCTTCAGCGTGTCTGGCAACCCGAAACCCAAACTCAGATGGTTATTAGACGAGCAACCCATTCAAGAGGGCAAGTTCATCCATACCATGATCCACGATTACTCGGAGGGCGAATACCACGGTTGTCTACAGCTGGACAGTCCCACGCACATCAACAACGGCATGTACACGCTGCTGGCCAGAAATCAATTCGGAGAGGACAGC[A/T]AGGCCGTATCTGCTCATTTCATGCATGAGCCATGGAACGGTGAGTTGAAATTAGCATGCATTCAAGTTAAAATTGTCAGGTTATACTTTTGCGTCGAGTGCATGGGGTAGATTCGATGGAGCGTTTGAGCAGTCACACACATTTCGCCGTATCCTGACGCGCACCCCTCAAAAAATAATGACAATATGTTTTGCCGACGTGGAGCGCAGGATCTGTCAGATTGGTAGTGGTCAGGGGCATCACTAGACCCCATTTATTAGGGCACGTGCCTCAGTAAAAATCGTCAGTGCCCTAATAAATGCTTTGAGATAAGATTGATATTTATTAGGAGTGGTAATCCCAAAATAAAGATGTCATTCATTATGCAACCCAACCAACGCTGATGAAAGCAATGTAGTGTGATCAAAAGGCAAACTGGGCATGCGCACAGAAAAAAAACCATACCCGCACGCCTCACACACCGCTCCTGCTGACTCACTGCTCTGCTCCCGGTGTTACGG
Associated Phenotype:
Not determined