ZMP

si:dkey-240n22.1

Ensembl ID:

ENSDARG00000095696

ZFIN ID:

ZDB-GENE-070705-407

Description:

Novel NACHT domain containing protein [Source:UniProtKB/TrEMBL;Acc:B0S5A0]

Human Orthologue:

NLRP6

Human Description:

NLR family, pyrin domain containing 6 [Source:HGNC Symbol;Acc:22944]

Mouse Orthologue:

Nlrp6

Mouse Description:

NLR family, pyrin domain containing 6 Gene [Source:MGI Symbol;Acc:MGI:2141990]

Alleles

There are 4 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa44596	Nonsense	Mutation detected in F1 DNA	Not yet available
sa40340	Nonsense	Mutation detected in F1 DNA	Not yet available
sa38445	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa44596

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000133855	Nonsense	26	107	3	5
ENSDART00000134357	None	None	975	None	7
ENSDART00000135345	Nonsense	26	527	3	7

Genomic Location (Zv9):

Chromosome 4 (position 60965162)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	75445961
GRCz11	4	77022699

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGTGTTTGTCTCTTCAGTGTGAGATCAGGATCATGTGTGAAGAGTGACTG[G/A]TCTAAAGAGGATCCACCAGAGTTCAGTGAGGAAACACCATCACCTGCCCA

Long Flanking Sequence:

ATGATGGACAAAGCTTCAGTTTACACCTTCAGGAAATGTTTTGAGAGTGTTCCGAGGTGTATGCGATGCTTTTAATGCGCACACCTCTCCATATGACATAATCACGCCACCGCTAACCCGACCCCTCACAGTGACGTCACTACCTCCACTGAGTGCAGTCTCAGCTTGCTCATGCAAGGCTGTATCCAGATACTATTGAATGTGTTGAGATCATTGTAGGTTATAAACAGCTTGGTCTGGTGTCATATTTACCAGAGCTGAATTTACTTAATTTGTCAAGTTATAAGACCTGTACAACATTAGAATTAACCGCAGAACAGTTTCAGCAGACCTGATCAGACAGACCTTCAGTCAACTATTAGTTAGTGCTAAATTAAACTGAGCAAACTCATATTTGGCTGATAAACTCTCAAAGGAGATTGAAGTTTGTCCTGCAGTTTATTCCTCTTGTGTGTTTGTCTCTTCAGTGTGAGATCAGGATCATGTGTGAAGAGTGACTG[G/A]TCTAAAGAGGATCCACCAGAGTTCAGTGAGGAAACACCATCACCTGCCCAAAGGTATTTTGGTGTTTTACATGCACTTCAAAGTATGTTGAAATTGGTTGTACTATTGGACAGCTAACGATTGAACTGATGGACTGTGCCTGTCAGGACTCCTGTTAGGTTGTGGTATTGTTTTGGCATTGTTTTGCCTCTACTACCGTGCTCCCTGACCCAGTTTCGCTCCTTTGTATTCAGTTGAATCAGGGGTGTCTTGTGACATCCTCCTTTGTTCTGTTTCCTGCCTTGGTTGCCTCATTAGTACATCTATGTTGATTGTTATTAGTGTGTATATATATCTAGGTTTATGTGTTTTAGCAGTCCAATGCCCTAACCATAACCCTCCACATTCACCGAGGACATTATTGTATTTTGCCAAGATCTACTTCCAGCCGGTGCAGAGTGATGGCTTCAGTCCCTGAGTGCCTGCCAATCATGGCTTTAGTCATGCCATCCAGGTTCCTT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa40340

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000133855	None	None	107	None	5
ENSDART00000134357	Nonsense	89	975	2	7
ENSDART00000135345	Nonsense	250	527	7	7

Genomic Location (Zv9):

Chromosome 4 (position 60971415)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	75452214
GRCz11	4	77028952

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGCTTCTAGATGTCATCAGTCACTAGAGATGAAGATTGAATGTAAACATT[T/A]GTTTGAAGCAGCTGAACAAGACAAGCAGATCAGAACTGTCCTGACAAAAG

Long Flanking Sequence:

GACAGATTTTTGAAGAATGAACTTGAGAAGTTTAAGAAGATCTTACAAGAAGAAAACAGACAAGACTTTGTAAAGAACTTTAATGACAACAGATGCAGAATCACAGAAGCAGCTCTTGATCTCACACTCTTCTTCCTGAGAGATATGAAGCAAGATGAAGTTGCTGATACTCTCCAGGGTAAGATACTCATGACCGTCAGTTTGTCACTTACAAATATAGCTGGAAAAGTCAAGACTAAACCTATCTCTTTCTTTGCTCCTGTGTTTAGGTGAGCTGTTCTTCATTAACCAGTTAAAATGTAGCATGAAGAAGAAATATCAAAGTGTGTTTGAAGGAAATGCTCAGCAAGGAGACTCCACACTTCTGAATACCATCTACACAGATCTCTATATCACTCAGGGTGCGAGTGAACAGGTCAACACTGAACATGAGATCAGACAGATTGAAGTTGCTTCTAGATGTCATCAGTCACTAGAGATGAAGATTGAATGTAAACATT[T/A]GTTTGAAGCAGCTGAACAAGACAAGCAGATCAGAACTGTCCTGACAAAAGGAGTTGCTGGCATCGGGAAATCAGTCTCTGTGCAAAAGTTTGTTCTGGATTGGGCTGAAGGGAAAGAAAATCAAGACATCAGCTTCATATTTCCTCTTCCATTCAGAGAGATGAACTTAAAGGAGAAAGAAAGACAAAGTTTAAAAGACCTCATAACTCAGTTTTTCCCAGAGACTAAAGGACTGAACCTTACAAGAAGCACACGATTCAAAGTCCTGTTCATCCTTGATGGATTGGACGAATTTCGTCTTCCCCTAAACTTTGTTGGTAATGAGACGTGTCGTGATGTATCTTCAGCAGTCTCTCTGGATGTTCTCCTGACGAACCTCATCAAGGGAAATCTGCTTCCTTCTGCTCTCATCTGGATCACCAGCAGACCAGCAGCTGCCAGTAAGATTCCTGCTGACTGTATCGACCGGCTGACAGAGATACAAGGATTCAATGATGCCC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa38445

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000133855	None	None	107	None	5
ENSDART00000134357	Essential Splice Site	727	975	5	7
ENSDART00000135345	None	None	527	None	7

Genomic Location (Zv9):

Chromosome 4 (position 60980841)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	4	75461640
GRCz11	4	77038378

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTCATGTGTGATTGTCCAACAGTGTGATGTGGACTGTTTGTGTGTTTGTA[G/A]ATTGTCTGGCTGTATGGTGACAGAGGAAGGCTGTGGTTTGCTGTCTTCAG

Long Flanking Sequence:

TTCGTCAATTGGTGAAGGTTTGTTCTTTGCCACTGTTCATTGCTTAGTTTGGAACTTGTGGAGCTACGCATGCATGGATTGCTCTTCAGTGTTTGGACTTTCAGCAGTGAAAATTAAATTACACTGAACTGAACTAAACTGAACTTCAACTCTGAAAAGTAGACGGACACAGTTTAGATGGACTAGATCTTCTATGTTAAGCTGTGTTGACACAATCTACATGGTAACAATACTATATAAATAAAGATTAATTGAATTGAAATAGAAAACAAGATGTGACACACCCACAGTGGTGCTTTTTATGTGATGTATTATCAACAATATCTTTGTTTTTAGACCTTGTTGAGTATTTTAGTGAGTTTGCTGACCTCAGCGGTTGATCGATTGGGAAAAGTAATCAGCATATGTGTTTTCATCACTGGTGTTCGAATGAACCGAAACACCAGCATTTTCATGTGTGATTGTCCAACAGTGTGATGTGGACTGTTTGTGTGTTTGTA[G/A]ATTGTCTGGCTGTATGGTGACAGAGGAAGGCTGTGGTTTGCTGTCTTCAGCTCTGACTTCAAACCCCTCACACCTGAGAGAGCTGGATCTGAGCTACAATCATCCAGGAGATTCAGGAGTCAAGCTGCTCTCTGAACAACTGGAGGATCCAAACTACACACTGGACACACTCAAGTATGTAGAGCATCACTGCCCTTTTACACTTAATGGCTTTAAAAACAAATGTAAAAAACTTTATTGAAATTCCGTTTTCTGTGAGAATTGTGGGGTTTGGGCATTCATAATATATAGACTTAAAAGACATCTAGGGACTAAAGACACAATGTGATGAAGTGTTTGTTTTGTCCCCTTCTTCCCGCAAACAAATCTTAATGTGGGCAACAGTCCTTTTTAGCAATAATAGTGCCATCACAGAAGTGCAAGTATTTTTGCCAAAAGCACTGACACAACCTCATACCATGACAAACCCTGGCTTCTGGACTTGTTGCTGGTAACAGTCT

Associated Phenotype:

Not determined