ZMP

si:dkey-7f3.15

Ensembl ID:

ZFIN ID:

Human Orthologues:

APOA1, APOA4, APOA5

Human Descriptions:

apolipoprotein A-I [Source:HGNC Symbol;Acc:600]
apolipoprotein A-IV [Source:HGNC Symbol;Acc:602]
apolipoprotein A-V [Source:HGNC Symbol;Acc:17288]

Mouse Orthologues:

Apoa1, Apoa4, Apoa5

Mouse Descriptions:

apolipoprotein A-I Gene [Source:MGI Symbol;Acc:MGI:88049]
apolipoprotein A-IV Gene [Source:MGI Symbol;Acc:MGI:88051]
apolipoprotein A-V Gene [Source:MGI Symbol;Acc:MGI:1913363]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa42717	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa36118	Nonsense	Mutation detected in F1 DNA	Not yet available
sa36119	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa42717

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000008651	Essential Splice Site	68	259	None	3
ENSDART00000143855	Essential Splice Site	86	277	None	4

Genomic Location (Zv9):

Chromosome 16 (position 26161376)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	16	24007051
GRCz11	16	23922083

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGGAATCCATTAAGATGATCAGAGAGTCTCAACTGGGTCAAGAAGTCAAG[T/A]AAGTCAAGAACATTTACCTGCTGGACATCATTATTTAGAGTATTTCTGAA

Long Flanking Sequence:

AAATACAGATGTGAAATATCCACCTTCACACTTGTTCCTCATACAGGACAGCATCAATTAAAGCACACCAACACAGGTAAGAGGACAGACTTACTTTCTTTCCATTTAAGGTACTGCTATAATGATGATTTGACAGAGAAAAAAAACAATGCTGATGAAACATGTCATTTAATTACAGACTAAAAGTGAAGACCATGAAGGTTCTTGTGGTGCTCACACTTGCTGTGGTTACAGGTAAGAAACTAAAATTATAATTAAACTTTTAGCCTCTTCAAAATGTTTCAGGCTTAATAAATTTAGTGTTTATTTACAACATCATTTAATCTGTTTAAATCTTTCAATCAACAGGCTGCCAGGCCAATATATTCTATGCTGATGAGCCCAAACCACAGCTGGAGCAGCTGACAGATGCATTCTGGAGCTATGTTTCTAAAGCAACACAAACCGCAGAGGAATCCATTAAGATGATCAGAGAGTCTCAACTGGGTCAAGAAGTCAAG[T/A]AAGTCAAGAACATTTACCTGCTGGACATCATTATTTAGAGTATTTCTGAATGAAACTCAAATGTTCTTCTTTACCTCACAGTGAAAGACTGACCCAGAGTGCTGATATGGCCAGTGAATACGCCGTCGTCCTCAAGAAACAGGTGGATCCTCTGACTGAAGAGCTGATGAACAAAATCACCAAGGAGACTGAAGTGCTGAGGGAGCGTCTGGGCCAGGACCTGATCAATGTGAGAGATAAACTCGAGCCCTATGCTGACAACATGAAGAGCCAGATCCAGCAGAGAGTGGAGGAGCTCAGGGCGGCCATGGCTCCGTATGCTGACTCCCTGGATTCTGAGACCCTGAAGGCCACTCTGCTCCAGAAGAGTGAGGAGCTGAGAGGAAACCTGGAGCAGAGTGTGAAGGAGCTGCAGGTTCAGCTGGAGCCCTACACTGCTGAACTCAAGGAGAAAGTGGACCAGCATCTGCAGGAGTTCCAGAAGACCGTGACTCCCCTGA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa36118

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000008651	Nonsense	125	259	3	3
ENSDART00000143855	Nonsense	143	277	4	4

Genomic Location (Zv9):

Chromosome 16 (position 26161629)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	16	24007304
GRCz11	16	23922336

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GAGCGTCTGGGCCAGGACCTGATCAATGTGAGAGATAAACTCGAGCCCTA[T/A]GCTGACAACATGAAGAGCCAGATCCAGCAGAGAGTGGAGGAGCTCAGGGC

Long Flanking Sequence:

ATTAAACTTTTAGCCTCTTCAAAATGTTTCAGGCTTAATAAATTTAGTGTTTATTTACAACATCATTTAATCTGTTTAAATCTTTCAATCAACAGGCTGCCAGGCCAATATATTCTATGCTGATGAGCCCAAACCACAGCTGGAGCAGCTGACAGATGCATTCTGGAGCTATGTTTCTAAAGCAACACAAACCGCAGAGGAATCCATTAAGATGATCAGAGAGTCTCAACTGGGTCAAGAAGTCAAGTAAGTCAAGAACATTTACCTGCTGGACATCATTATTTAGAGTATTTCTGAATGAAACTCAAATGTTCTTCTTTACCTCACAGTGAAAGACTGACCCAGAGTGCTGATATGGCCAGTGAATACGCCGTCGTCCTCAAGAAACAGGTGGATCCTCTGACTGAAGAGCTGATGAACAAAATCACCAAGGAGACTGAAGTGCTGAGGGAGCGTCTGGGCCAGGACCTGATCAATGTGAGAGATAAACTCGAGCCCTA[T/A]GCTGACAACATGAAGAGCCAGATCCAGCAGAGAGTGGAGGAGCTCAGGGCGGCCATGGCTCCGTATGCTGACTCCCTGGATTCTGAGACCCTGAAGGCCACTCTGCTCCAGAAGAGTGAGGAGCTGAGAGGAAACCTGGAGCAGAGTGTGAAGGAGCTGCAGGTTCAGCTGGAGCCCTACACTGCTGAACTCAAGGAGAAAGTGGACCAGCATCTGCAGGAGTTCCAGAAGACCGTGACTCCCCTGACCGAGGATCTGCAGGTCCAGATTAGAGAGAGAGCCCAGATGGTCCAGCAGAGTCTTACACCCTATGCTGAAGATGTGAAGGAGAAGCTGGACCCCTATGCACAGAACTTGAAGGACCAGCTCGCTTCTCTGTATGACTCTTTCATCAAGAGAAATTAAATGCATTAAAGACTTCTCTTTTTTACCAAATTAACTCTTCACAAACTTCGAAATTTGACATATTTGATCCATGTTTTTTTCTATCGATTCATCCT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa36119

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > G

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000008651	Nonsense	252	259	3	3
ENSDART00000143855	Nonsense	270	277	4	4

The following genes are also affected by this mutation:

ENSDARG00000040298

Genomic Location (Zv9):

Chromosome 16 (position 26162010)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	16	24007685
GRCz11	16	23922717

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AAGCTGGACCCCTATGCACAGAACTTGAAGGACCAGCTCGCTTCTCTGTA[T/G]GACTCTTTCATCAAGAGAAATTAAATGCATTAAAGACTTCTCTTTTTTAC

Long Flanking Sequence:

AAGAAACAGGTGGATCCTCTGACTGAAGAGCTGATGAACAAAATCACCAAGGAGACTGAAGTGCTGAGGGAGCGTCTGGGCCAGGACCTGATCAATGTGAGAGATAAACTCGAGCCCTATGCTGACAACATGAAGAGCCAGATCCAGCAGAGAGTGGAGGAGCTCAGGGCGGCCATGGCTCCGTATGCTGACTCCCTGGATTCTGAGACCCTGAAGGCCACTCTGCTCCAGAAGAGTGAGGAGCTGAGAGGAAACCTGGAGCAGAGTGTGAAGGAGCTGCAGGTTCAGCTGGAGCCCTACACTGCTGAACTCAAGGAGAAAGTGGACCAGCATCTGCAGGAGTTCCAGAAGACCGTGACTCCCCTGACCGAGGATCTGCAGGTCCAGATTAGAGAGAGAGCCCAGATGGTCCAGCAGAGTCTTACACCCTATGCTGAAGATGTGAAGGAGAAGCTGGACCCCTATGCACAGAACTTGAAGGACCAGCTCGCTTCTCTGTA[T/G]GACTCTTTCATCAAGAGAAATTAAATGCATTAAAGACTTCTCTTTTTTACCAAATTAACTCTTCACAAACTTCGAAATTTGACATATTTGATCCATGTTTTTTTCTATCGATTCATCCTATCATGCCATAAATTAAGTCTAGTTTCCTAACTGTGCAATATTCAATGTCCTTTACATTTGCAAATGTTCTGTTTTAATGTGTGGTGCTGGATATTTATTTAATAAAATATCAAATATTTTTCAGACAAAATGTTTGTGATGTTTACAAATGCCACACATTTGACCATAACTATCAATCATTCATTCATTCATTTCCTTTTTGGCTTAGTCCTTTTATTAATCTGGGGTCGCGAAAGGAGAATGAACTGCTAACTTCAGCATATGATTTACGCCGCGGATGCCCTTTCAGCTGCAACACATCACTGTGAAACACCCATACACTCCCATTCACTACGAACAATTAACCAACCCAATTCACCTATACCACGTCTTTGGATTTG

Associated Phenotype:

Not determined