ZMP

si:dkey-246e1.1

Ensembl ID:

ENSDARG00000094839

ZFIN ID:

ZDB-GENE-070705-415

Description:

Novel protein similar to vertebrate rho-associated, coiled-coil containing protein kinase 2 (Rock2)

Human Orthologues:

ROCK1, ROCK2

Human Descriptions:

Rho-associated, coiled-coil containing protein kinase 1 [Source:HGNC Symbol;Acc:10251]
Rho-associated, coiled-coil containing protein kinase 2 [Source:HGNC Symbol;Acc:10252]

Mouse Orthologues:

Rock1, Rock2

Mouse Descriptions:

Rho-associated coiled-coil containing protein kinase 1 Gene [Source:MGI Symbol;Acc:MGI:107927]
Rho-associated coiled-coil containing protein kinase 2 Gene [Source:MGI Symbol;Acc:MGI:107926]

Alleles

There is 1 allele of this gene:

Allele Name	Consequence	Status	Availability
sa14278	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa14278

Status:

Available for shipment
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Availability:

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Mutation:

T > G

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000141262	Nonsense	26	334	1	8

Genomic Location (Zv9):

Chromosome 22 (position 27702873)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	22	27223636
GRCz11	22	27086088

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GTGACTCTGACCAAYAACTATGAMATMCCAAAGGAATGGGCTCAATTCTA[T/G]ACGGCAGAAGTGGTGCTGGCACTTGACGCCATCCATTCTCATCCATTCTC

Long Flanking Sequence:

GTACATGTTATGAAGATGCAAATTTAAATTTTGGGTTTGATTAATTATGATTAATTGCTTGACACAACTGTTTTTGTGTATGTATATGTTCATACTTAAAATGTCATTTAATATTACATTTATAATTTTTATATTTTAAATTTATTATTTACATTCTGTAATTGATAGCATTAAAAGTTCTTTAATACCAGTATTTAAATTCTGAAATAAATATTCAAACGGTTAAATAAAGTCTGTGTTTAATATCACATTACTTATTATTTAATTTAGCTGGGTTGCTGCAATTGAAATGGAGTATTGTTAAATTTCACTGGTATTAATTACTGAAATATATTGTGAATTCTCTTTTCACCACTCTATCTCTCTGTCCACATACAGTAGCTGTGCTGTGCATTCCAACATGAAAAGTACCTTTATTTGGTGATGGAGTTCATGCCAGGTGGAGATCTGGTGACTCTGACCAACAACTATGACATCCCAAAGGAATGGGCTCAATTCTA[T/G]ACGGCAGAAGTGGTGCTGGCACTTGACGCCATCCATTCTCATCCATTCTCATCCATTCAACCTGCTGCTGGACCGCAATGGACACCTCAAACTTGCAGACTTTGGCACATGCATGAAGATGGACTCGGTGTGTGATAAGTGCATTAGAAGTGTCTTTTAAGGGGGTTTGATACTAACAAAAATGTTTCTCTCCTTTTTTTGATAATTTCATTGAAAAATATTTTGCTTAGTGTAATTATGTGCTGATTCCTTGGCTAGTTTAGGCCTGAAGTGGATTAATAGATATGACCACTAGGTGACACCACTACTGTAGGTCACAGCAAGTCTCTTACTCCTTTTCAAAAATGGTAGGCTACTATCTAAATCGGTACTTCATTTAAGTTCTAAGTTGTGTCTTGACAATAATAAAATAGAATAGTGGAAGTGAGAATGAAATTCAGGCTGTTGCATTGACGTTGTTGTCACCTCATGTTAACCTTTCGTCATCAGGCCTCATAGGA

Associated Phenotype:

Not determined