ZMP
twf1l
Ensembl ID:
ZFIN ID:
Description:
Twinfilin-2 [Source:UniProtKB/Swiss-Prot;Acc:Q6GMH3]
Human Orthologue:
TWF2
Human Description:
twinfilin, actin-binding protein, homolog 2 (Drosophila) [Source:HGNC Symbol;Acc:9621]
Mouse Orthologue:
Twf2
Mouse Description:
twinfilin, actin-binding protein, homolog 2 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1346078]
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa26804 | Splice Site, Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa16143 | Nonsense | Available for shipment | Available now |
Mutation Details
Allele Name:
sa26804
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Splice Site, Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000065006 | Splice Site, Nonsense | 124 | 347 | 3 | 8 |
The following transcripts of ENSDARG00000094792 do not overlap with this mutation:
The following genes are also affected by this mutation:
Genomic Location (Zv9):
Chromosome 6 (position 41416990)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 6 | 41488590 |
| GRCz11 | 6 | 41486126 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAAAGAGTTTGGTGGTGGACACGTCAAAGATGAGATGTTTGGCACAGTT[G/T]AGGTAAGCAGAATGAGTTTCATTTCATTCATTCATTCATTCATTCATTCA
Long Flanking Sequence:
GTTTTTCTTTCAGACTGTAGGGTCATTCTAAAAACTTTGTTGTTGTTGTTGTTTTATTTTACTTCATTCATTCATTAATTTTCCTTCGGGTTTGTCTCTGATTTATCAGGAGTTGCCACAGCGGAATGAACCGTCAACTACTCTGGGATATGCTTTATCTTTAAGCCGCAACCCAGTACTGGGAAATTGATTTTACTTAAATATTTCAATTACTTCAGTCACTTGCTATTTTGTTTGCAAAATTTGCTGTAAATTTTTGACCATTGTCTTGAATCTATCCAGGACATTCTTGCGATTCTTGCTACCATTTTTGTTTGAAAATGTAAAAAATCGAATTGTAATACAGCACATATTACCACACTATAGATGATTCATTCAGTAAACTGATCATCTACCTTTCACTGCAGGTCCGACAGAAGATGCTTTACGCTGCCACTCGCGCCACAGTGAAGAAAGAGTTTGGTGGTGGACACGTCAAAGATGAGATGTTTGGCACAGTT[G/T]AGGTAAGCAGAATGAGTTTCATTTCATTCATTCATTCATTCATTCATTCATTCATTCATTTTCCTTTGCCTTAGTCCCTTATTTATCAGGGGTTACCACAGCAGAATGAACCAAAAATCATTTTAGCATACAGTATGTTTTACGCTGCAAATGCCCTTCCAGCCGGAACTCAGTACTGGAAAACACATACACTCACATTCACACACATATTCACACCTTACAGCCAATTTAGTTTACCCAATTCACCTATTAACCTTATTCTACAATGCGGAAGTGTGTTCTTTTTTGCGATTGTTTTAGAACTTCCGATTCAGTTGCCTATGAGAAAAATGACTAGGAATAATAAATAGCAGAAAACGGTCAAACTACTTGCTCTACAAACAAGTGCTTGCATGAATATACAGACAAAGATGAATAATATAATAAGAAAATGTCATCAAGCAGCAAAATGAGCTGTTTTTAACGTCTAAAAATGAATGGGAGTGGGAATGAGTCTGCTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa16143
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000065006 | Nonsense | 181 | 347 | 5 | 8 |
The following transcripts of ENSDARG00000094792 do not overlap with this mutation:
The following genes are also affected by this mutation:
Genomic Location (Zv9):
Chromosome 6 (position 41424272)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 6 | 41495872 |
| GRCz11 | 6 | 41493408 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCAGTGTGGACCCCAAACATCAGACTCTACAGGGTCTTGCTTTTCCMTTA[C/T]AGGCTGAAGCCAAACGTGCTTTAAAGCASCTCGCAGAGAGACGCATCAAC
Long Flanking Sequence:
TAAATTAAAAACAATGAAAAGTAAATTTAAAGTAAGTCAAACATAACAAAATTATCGCAAAAGAAAACAAAAATTTTTAAGTAGAATTCTTTTTAAAGCTATGAAACTGATAGTCCTTAATAGTAAACAAAAAGAAAACAGGGCTTTCTGGTAAAACAAAACATATTTCGGTGTCAAGTGAGGACAGTTCTAAACAGGTGTGTTGTGATTCAAATATACAGTCATTACATTCATTCAGCATATTACCACTCTGCTTTTCCATTTACTCTTATCCACCATCTCCACCCACATAAACATACTTTTCCAAACAACACAACTGCCATATAATAAGTCTTCCAGCACTGGATCATAGGAATTGTTTTGGAAAAAGGTTTTGATAGATTGGCTGGAACTGTTGCTGCAATACAAACTTTGTATGTGTGTGTATGTGTCTGCAGGTGAAGGCTGAGATCAGTGTGGACCCCAAACATCAGACTCTACAGGGTCTTGCTTTTCCATTA[C/T]AGGCTGAAGCCAAACGTGCTTTAAAGCAGCTCGCAGAGAGACGCATCAACTACATTCAACTGGTACGACACCTTCATATTACACTGCCCTCCACTAATACTGGCCAATGAGGCAAAAAAAAAAGTTTGTTGTTTAACCTTTTGACTTTCGACTTAAAATACTGACAATTAAAGTTGGGGTGGCATGGTGACTTAGTGGTTAGCACTGTCACCTCACAGCAAGAAGGTCACTGGTTTGAGTCTCGGATGGTCAGTTGTCATTTCTGTGTGGAGTTTGCATGTTCTCCCCGTGTTCATTCCTCCAGTGCTCTGGTTTCCGCCACAGACCAAAGACATGCAGGTGAATTGAACAAACTAAACTGACCGTAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGTGAATGAGAGAGTGTTTGGGTGTTTCTAAATAC
Associated Phenotype:
Not determined