Busch Lab

ZMP

txnrd2

Ensembl ID:
ENSDARG00000094470
ZFIN ID:
ZDB-GENE-081104-217
Description:
Novel protein similar to vertebrate thioredoxin reductase 2 (TXNRD2) [Source:UniProtKB/TrEMBL;Acc:B8
Human Orthologue:
TXNRD2
Human Description:
thioredoxin reductase 2 [Source:HGNC Symbol;Acc:18155]
Mouse Orthologue:
Txnrd2
Mouse Description:
thioredoxin reductase 2 Gene [Source:MGI Symbol;Acc:MGI:1347023]

Alleles

There are 2 alleles of this gene:

Allele Name Consequence Status Availability
sa8420 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

This allele has been removed from public view.

Allele Name:
sa1389
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000139203 Nonsense 131 206 4 6

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 17019117)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 14814985
GRCz11 5 15315202
KASP Assay ID:
554-1301.1 (used for ordering genotyping assays)
KASP Sequence:
TACAAACCGCTGGAGTTCACTGTGGCTGAGAGAGATGCCACTCAATGCTA[T/A]ATAAAGGTATTTTAARYAATATTTTCTTTAAATATAGGTTTAAGTAATAC
Long Flanking Sequence:
TTTGTGTGTGCTGTTGTAAATATCTTACAGTATACGTGTATATGTGTGTGCGTGTGTATGTACTGAGTCCTCACACACCTGCGTTGCTCTAAAGCCTTAAGCATTCACAGAGGGGCGTGCCTCTAGTTTGATTGACATGTGCGCAGGAGGGCTGACTGATGCTTCTAGAGGTTGATGAGAGATGATCAGAAACGCTGCATCTCATTGGCTCTGACAGCTGTGAGCGGCGTGTGTTGGCACGCTAGAACATTCGCTCTTTAACATCTTCAATATGCATGATTTCAGCACCCCAAAAATGTTTAAGACCAAAACACAGACGCAAACCATAACAGTAGCAGCACTTGTCCTGAAATGACGAGCTCAAGTGCTTGATGATTCAGGAAATGTCATCAGCGTTGGCGCATCATAGTTTTCTTGTGTTGTCTGGTTTAACAGGTGTACCATGCTTTCTACAAACCGCTGGAGTTCACTGTGGCTGAGAGAGATGCCACTCAATGCTA[T/A]ATAAAGGTATTTTAAATAATATTTTCTTTAAATATAGGTTTAAGTAATACAAATCGGATGCAATATAGTCTGTGCTGCTTCTGTTGATGCATTAATCAAACCACTTGGTATTTTATGGTGCACCGTTTAAAATCTAAGGGTGACAAAGCTATTTCTGGTGCCTGCCCCTCATCTATGAAACCAGTCTTGCCGCTTTGCACATTTCATAAGGCTAGGCAAGACATTTCATTACTCATTTTTAAATCAAGGTTGAAAACTTAGCATTTTAATTGTCTCCTTAGCATTTTCATTGTGTTCTCTTTGGTATTTTGTCATTCATCTTGTCCGTCTTGTTTTAATTTATTTTTTTTTTACTCTGAGCACTTTGGATAGCTTGTTTAATTTGCTACTTTATATAAATACATTTTACTTACCTCCTGTTAAGTAATCACAAGAAACTTTGTTTTTTACTACATTTAATACATTCATTTATTTTCTTTTCGGCTTAGTCCCTTTAATAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8420
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000139203 Essential Splice Site 166 206 None 6

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 5 (position 17015823)
Other Location(s):
Assembly Chromosome Position
GRCz10 5 14811691
GRCz11 5 15311908
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGGGCCGAACGCTGGTGAAGTCACACAGGGCTTTGCTTTGGGCTTCCAG[T/C]ACGTTCCRCACRTCTCTGTAAACTTGCACATGATGMTGGGCTGGAATCAG
Long Flanking Sequence:
CTAATATTCAGTTTAAAGTGTGATTCAAAGGCTTAACTAGGTTATCTAGGCAAGTTAGTGTAATTGGGCAAGTTATTGTTTAAGTGGTTTGTTCTTTTGACAATCGAAAAAAATGTTGCTAAAAAGAGCTAATAATACTGACCATACATTTTTTTTTAAGAAATTAAAAACATAAAATAAAACAAATAAGACTTTCTCCAGAAAAAAAATAAATAAATAAATAAAATTAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAATTTGGGAAATATTTAAAAAAGAAAAAACAATTCAAAAAAGGCCTAATAATTGCAACTTCAACTGTGTATATGCTCTTTTTCGCAGGTGGTTTGTCTACGAGAAGGTGACCAGCGCGTGCTGGGTCTGCATTTTACTGGGCCGAACGCTGGTGAAGTCACACAGGGCTTTGCTTTGGGCTTCCAG[T/C]ACGTTCCGCACATCTCTGTAAACTTGCACATGATGATGGGCTGGAATCAGATTACATTGATTTGATTTGATGTGTTCTGATGTCCCCCAGGTGTCTGTTTCATTACATGCACATTTGCATGTGAATTCAAATCAGCATTTGTATGGACAGCTGCGGATGAATGAATACAGACTCTGTGTGTTTCTGTCTGCAGGTGTGGACTTACATACGAACACCTCAGGAACACAGTGGGGATTCACCCCACCTGTGCTGAGGAGCTCACCAAACTCAACATCACCAAACGCTCGGGTCTTGACGCCACGGTGACAGGCTGCTGAGGTTAAGCATCCCCTTTCCTGATACTGCAAGCACACGGGAGCCTGTTCGGAGGGTTGGGATAATGTAAGTTCTGGAGGAAGCATCTCATGAAAACACAGCAGGTTTTGGCATTTGGTTAAATGTAAAAATTGAAGTTTTGTCCAAATTTACCCACTCTAAACTCCTTCCAAATATTCCAAAAA
Associated Phenotype:
Not determined