Busch Lab

ZMP

zgc:136461

Ensembl ID:
ENSDARG00000093844
ZFIN ID:
ZDB-GENE-060519-7
Description:
hypothetical protein LOC562139 [Source:RefSeq peptide;Acc:NP_001075159]
Human Orthologues:
CTRB1, CTRB2
Human Descriptions:
chymotrypsinogen B1 [Source:HGNC Symbol;Acc:2521]
chymotrypsinogen B2 [Source:HGNC Symbol;Acc:2522]
Mouse Orthologue:
Ctrb1
Mouse Description:
chymotrypsinogen B1 Gene [Source:MGI Symbol;Acc:MGI:88559]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa11393 Nonsense Available for shipment Available now
sa25368 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa34120 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa11393
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000022139 Nonsense 48 263 2 7

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 7 (position 36522967)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 34796810
GRCz11 7 35068287
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATGCCAGGATTGTRAACGGTGAGGAGGCTGTCCCTCATTCCTGGCCCTGG[C/T]AGGTGTCTCTGCAGRTATGAAYAGACAGATTTTCACTTACAGATGACATT
Long Flanking Sequence:
GTCATTTGTTTGAGATGAAATGCATAATATATATTCCACTTTTATGAAATCATGTCCATGAAATATGACAGACCTTCTTCCGATACAATTAGCTCCTGCAAGTGTTAGCAATAACAAGTGACACGTACAGCTAAAAGTGCTCAAAGTACTCAATGGAAAGTCAGCAAATTCTGAGAATGAGAATGTTGCAAAATATGTAAATAAGCAGGAAGGTCAGATATATAAACCCCTCGAGTTGGTGAGACATTGGTGACTCAGAAATGGCTTTCGTCTGGATTTTGTCGTGCCTTGCCTTGATTGGAACAGCATATGGTAAATTGCTGATTTTTTCCCTCTTATTTAACAATTTGAATGAATGTGTCCCACTTTGATTTATATAAAAATTTTAACAAGTGCTTTTTTATTCTGAAGGCTGTGGCGTTCCTGCCATCCCTCCTGTTATTACCGGTTATGCCAGGATTGTAAACGGTGAGGAGGCTGTCCCTCATTCCTGGCCCTGG[C/T]AGGTGTCTCTGCAGGTATGAACAGACAGATTTTCACTTACAGATGACATTAGGATAGGCAACTGTGAATAAAAAAATTGATCTGATGTTTAATGTAAGGACTCCACCGGCTTCCACTTCTGCGGAGGCTCCCTGATCAACGAGTGGTGGGTTGTGACTGCTGCTCACTGCAACGTCAGGTAAGACAGCATTGACGCTTTGTTTCTCCATCATGCAATGAATTTAAGACGTATGTGCAAATTTGAGAGTAAAATAGTCAAATCTTTTTATTAGGACCTCTCACCGTGTCATCCTGGGTGAGCATGATCGTTCCTCCAATGCTGAGCCCATTCAGACCATGACCGTTGGAAAGGTATGGTGAACTCTAAAAAATGCTAGGTCATTGTTACTCCATGTTGGGTCAAATTTAGATAAATCCAACAGTTGGGTTAAAACGTGTCATTTACATGGTTTAAATGTTGGGTTTGTCCATATTTAACCCAATGCTGGGTTAGGACAAAC
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa18877
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000022139 Essential Splice Site 52 263 2 7
ENSDART00000022139 Essential Splice Site 52 263 2 7

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 7 (position 36522982)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 34796825
GRCz11 7 35068302
KASP Assay ID:
554-6140.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACGGTGAGGAGGCTGTCCCTCATTCCTGGCCCTGGCAGGTGTCTCTGCAG[G/A]TATGAACAGACAGATTTTCACTTACAGATGACATTAGGATAGGCAACTGT
Long Flanking Sequence:
TGAAATGCATAATATATATTCCACTTTTATGAAATCATGTCCATGAAATATGACAGACCTTCTTCCGATACAATTAGCTCCTGCAAGTGTTAGCAATAACAAGTGACACGTACAGCTAAAAGTGCTCAAAGTACTCAATGGAAAGTCAGCAAATTCTGAGAATGAGAATGTTGCAAAATATGTAAATAAGCAGGAAGGTCAGATATATAAACCCCTCGAGTTGGTGAGACATTGGTGACTCAGAAATGGCTTTCGTCTGGATTTTGTCGTGCCTTGCCTTGATTGGAACAGCATATGGTAAATTGCTGATTTTTTCCCTCTTATTTAACAATTTGAATGAATGTGTCCCACTTTGATTTATATAAAAATTTTAACAAGTGCTTTTTTATTCTGAAGGCTGTGGCGTTCCTGCCATCCCTCCTGTTATTACCGGTTATGCCAGGATTGTAAACGGTGAGGAGGCTGTCCCTCATTCCTGGCCCTGGCAGGTGTCTCTGCAG[G/A]TATGAACAGACAGATTTTCACTTACAGATGACATTAGGATAGGCAACTGTGAATAAAAAAATTGATCTGATGTTTAATGTAAGGACTCCACCGGCTTCCACTTCTGCGGAGGCTCCCTGATCAACGAGTGGTGGGTTGTGACTGCTGCTCACTGCAACGTCAGGTAAGACAGCATTGACGCTTTGTTTCTCCATCATGCAATGAATTTAAGACGTATGTGCAAATTTGAGAGTAAAATAGTCAAATCTTTTTATTAGGACCTCTCACCGTGTCATCCTGGGTGAGCATGATCGTTCCTCCAATGCTGAGCCCATTCAGACCATGACCGTTGGAAAGGTATGGTGAACTCTAAAAAATGCTAGGTCATTGTTACTCCATGTTGGGTCAAATTTAGATAAATCCAACAGTTGGGTTAAAACGTGTCATTTACATGGTTTAAATGTTGGGTTTGTCCATATTTAACCCAATGCTGGGTTAGGACAAACAGAGTGGATATTATA
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa3647
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000022139 Essential Splice Site 52 263 2 7
ENSDART00000022139 Essential Splice Site 52 263 2 7

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 7 (position 36522982)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 34796825
GRCz11 7 35068302
KASP Assay ID:
554-6140.1 (used for ordering genotyping assays)
KASP Sequence:
ACGGTGAGGAGGCTGTCCCTCATTCCTGGCCCTGGCAGGTGTCTCTGCAG[G/A]TATGAAYAGACAGATTTTCACTTACAGATGACATTAGGATAGGCAACTGT
Long Flanking Sequence:
TGAAATGCATAATATATATTCCACTTTTATGAAATCATGTCCATGAAATATGACAGACCTTCTTCCGATACAATTAGCTCCTGCAAGTGTTAGCAATAACAAGTGACACGTACAGCTAAAAGTGCTCAAAGTACTCAATGGAAAGTCAGCAAATTCTGAGAATGAGAATGTTGCAAAATATGTAAATAAGCAGGAAGGTCAGATATATAAACCCCTCGAGTTGGTGAGACATTGGTGACTCAGAAATGGCTTTCGTCTGGATTTTGTCGTGCCTTGCCTTGATTGGAACAGCATATGGTAAATTGCTGATTTTTTCCCTCTTATTTAACAATTTGAATGAATGTGTCCCACTTTGATTTATATAAAAATTTTAACAAGTGCTTTTTTATTCTGAAGGCTGTGGCGTTCCTGCCATCCCTCCTGTTATTACCGGTTATGCCAGGATTGTAAACGGTGAGGAGGCTGTCCCTCATTCCTGGCCCTGGCAGGTGTCTCTGCAG[G/A]TATGAACAGACAGATTTTCACTTACAGATGACATTAGGATAGGCAACTGTGAATAAAAAAATTGATCTGATGTTTAATGTAAGGACTCCACCGGCTTCCACTTCTGCGGAGGCTCCCTGATCAACGAGTGGTGGGTTGTGACTGCTGCTCACTGCAACGTCAGGTAAGACAGCATTGACGCTTTGTTTCTCCATCATGCAATGAATTTAAGACGTATGTGCAAATTTGAGAGTAAAATAGTCAAATCTTTTTATTAGGACCTCTCACCGTGTCATCCTGGGTGAGCATGATCGTTCCTCCAATGCTGAGCCCATTCAGACCATGACCGTTGGAAAGGTATGGTGAACTCTAAAAAATGCTAGGTCATTGTTACTCCATGTTGGGTCAAATTTAGATAAATCCAACAGTTGGGTTAAAACGTGTCATTTACATGGTTTAAATGTTGGGTTTGTCCATATTTAACCCAATGCTGGGTTAGGACAAACAGAGTGGATATTATA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa25368
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000022139 Essential Splice Site 53 263 None 7

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 7 (position 36523064)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 34796907
GRCz11 7 35068384
KASP Assay ID:
554-7835.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATTAGGATAGGCAACTGTGAATAAAAAAATTGATCTGATGTTTAATGTA[A/G]GGACTCCACCGGCTTCCACTTCTGCGGAGGCTCCCTGATCAACGAGTGGT
Long Flanking Sequence:
GCAAGTGTTAGCAATAACAAGTGACACGTACAGCTAAAAGTGCTCAAAGTACTCAATGGAAAGTCAGCAAATTCTGAGAATGAGAATGTTGCAAAATATGTAAATAAGCAGGAAGGTCAGATATATAAACCCCTCGAGTTGGTGAGACATTGGTGACTCAGAAATGGCTTTCGTCTGGATTTTGTCGTGCCTTGCCTTGATTGGAACAGCATATGGTAAATTGCTGATTTTTTCCCTCTTATTTAACAATTTGAATGAATGTGTCCCACTTTGATTTATATAAAAATTTTAACAAGTGCTTTTTTATTCTGAAGGCTGTGGCGTTCCTGCCATCCCTCCTGTTATTACCGGTTATGCCAGGATTGTAAACGGTGAGGAGGCTGTCCCTCATTCCTGGCCCTGGCAGGTGTCTCTGCAGGTATGAACAGACAGATTTTCACTTACAGATGACATTAGGATAGGCAACTGTGAATAAAAAAATTGATCTGATGTTTAATGTA[A/G]GGACTCCACCGGCTTCCACTTCTGCGGAGGCTCCCTGATCAACGAGTGGTGGGTTGTGACTGCTGCTCACTGCAACGTCAGGTAAGACAGCATTGACGCTTTGTTTCTCCATCATGCAATGAATTTAAGACGTATGTGCAAATTTGAGAGTAAAATAGTCAAATCTTTTTATTAGGACCTCTCACCGTGTCATCCTGGGTGAGCATGATCGTTCCTCCAATGCTGAGCCCATTCAGACCATGACCGTTGGAAAGGTATGGTGAACTCTAAAAAATGCTAGGTCATTGTTACTCCATGTTGGGTCAAATTTAGATAAATCCAACAGTTGGGTTAAAACGTGTCATTTACATGGTTTAAATGTTGGGTTTGTCCATATTTAACCCAATGCTGGGTTAGGACAAACAGAGTGGATATTATAAGTAACACACTTATGTCAATTAGATAATAATTTAACACAGATGAGAAATCTGCTGCTGCAAGACAGGATAATTGGTCAATGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34120
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000022139 Essential Splice Site 166 263 None 7

The following genes are also affected by this mutation:

Genomic Location (Zv9):
Chromosome 7 (position 36524035)
Other Location(s):
Assembly Chromosome Position
GRCz10 7 34797878
GRCz11 7 35069355
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATCATTTTCTTTCGTGCAAGCTTTCAAACACATTTTTGTAACTTTTTTTT[A/T]GCTCCTGATACCCCTGCCCTGCTCCAGCAGGCCGCTCTGCCTCTGCTGAC
Long Flanking Sequence:
CTGCTGCAAGACAGGATAATTGGTCAATGGAATGCTTACATGTCCATATTTTCTTTACAAAGGTTTTCAAGCATCCTAATTTCAACATGTTCACCATCAACAATGACATCCTGCTGATCAAGCTGGCCACTCCTGCTAAGATCAACACTCATGTGTCTCCTGTGTGTCTCGCCGAGACCAACGACAACTTCCCTGGTGGCATGAAGTGTGTGACCTCCGGATGGGGCCTGACCAAACACAATGGTATAAATATTTTCAAAATTTGAGTCACATTTATTATCTTATCTGTAAAAATGAAAGTTTGGTGGTTTAAAATTGTATAAATATGTAATCATATTTTTTATGCTTACTGTATAATATTTCATTGTATGCATAACATATCTTTATGTTACCATATTTCAAACTTAACCTTTTTAGGTTAATTATCCAATTAATTCTCTATAATCGTGAATCATTTTCTTTCGTGCAAGCTTTCAAACACATTTTTGTAACTTTTTTTT[A/T]GCTCCTGATACCCCTGCCCTGCTCCAGCAGGCCGCTCTGCCTCTGCTGACCAATGAAGACTGCAAACGCTTCTGGGGAAACAAAATCACTGATCTAATGGTCTGTGCTGGAGCATCTGGTGCTTCTTCCTGCATGGTAAGTCCTTCTGTTTTTCTCAGTTTACCTCTCTATTTGTCAAGTTTTCAAACACGGTATATATCTGACTTATATTTTGCCTGTTTCAGGGTGACTCTGGTGGTCCTCTGGTGTGTCAGAAAGATGGAGTCTGGACTCTGGTTGGTATCGTGTCCTGGGGTAGCAGCGTTTGCTCCACCAGTTCTCCCGGTGTTTACGCCCGCGTCACCAAGCTCCGTGCCTGGGTTGACCAGACCATCACTGCAAACTAAATCACCAAGCTAATGTTCATGGTCATAATGTTCATCAATAAAGCTTTATTTTGAAAAAAAAGAAAACACCCTGCTTGTTATTATGCTTTAAAGTAATTTACAATAGACATTTAA
Associated Phenotype:
Not determined