ZMP
nipbla
Ensembl ID:
ZFIN ID:
Description:
Novel protein similar to vertebrate Nipped-B homolog (Drosophila) (NIPBL) [Source:UniProtKB/TrEMBL;A
Human Orthologue:
NIPBL
Human Description:
Nipped-B homolog (Drosophila) [Source:HGNC Symbol;Acc:28862]
Mouse Orthologue:
Nipbl
Mouse Description:
Nipped-B homolog (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1913976]
Alleles
There are 2 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa8770 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa1954 | Essential Splice Site | F2 line generated | Not yet available |
Mutation Details
Allele Name:
sa8770
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000134510 | Nonsense | 116 | 1189 | 3 | 28 |
| ENSDART00000141735 | None | None | 315 | None | 8 |
The following transcripts of ENSDARG00000093281 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 8306136)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 7555024 |
| GRCz11 | 5 | 8059662 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTAGTTAGTATTTGAAATGGATATTTTGATTATTTCAGTTGCAAGACGTT[T/A]AAAGATGAAGCAGAAGAAGAGGAAAGTGTATGAGCCCAAGCKGACTCCTG
Long Flanking Sequence:
AGCTCACGGCTATCAGCATCGCCCACACTAGTCACTGATACCAAGCTGACCAATCACACAGCTTGCGCTATGTGTTGTTGCGATTATGTAGTTACATTTTTTGAGGGATCGCGCAAACGCTGTGCTGGATCTCACGAGTTCACTTGATGCAGAAGTATAAATCAGCCCTATGGGTGAAAAAACACTGAAAAAATTATTCATTGGATTTACAAACATTTTTTTAGGTAAGTGGTTGCAAACAATTTATATTGGAATTTAAACAACAAATTAAATTTAGTAATGTTAAACTTGTTTGATTAAATTCAGCTTGTTCGTAACAGCTTGTTCAGTGTACCTGCTTAAAAATCAAAGCCAGCTTCATGCAACAGGCCTTAATGAAGCGCTAGTGTGATATTTTTTTTATATATTTATTTATTTATTTTTTATATGAGGTCTCATTTTTGAATGTGTTTAGTTAGTATTTGAAATGGATATTTTGATTATTTCAGTTGCAAGACGTT[T/A]AAAGATGAAGCAGAAGAAGAGGAAAGTGTATGAGCCCAAGCTGACTCCTGAAGGTAAACCCCTTGACTTTTCTCTCATCATTGCACTAAATTATTCCCGGAATAATACTCAATGTTTATTCTCAGAAATGATGGACTCTTCCACCTTTAAGAGGTTCACGTTGAGTATTGACAACATCTTGGAGAATCTCGAGGATGTGGACTTTACAGCTCAGGGTATAGTACATATGTGTTTTATTATTAGTTTTAAATGGCACACCAAACTCTTTCAGCTTTTGACTTGTTTTGCATTGTTTTTCAGATGATGATGAGATCCCTCAGGAGCTGTTGTTGGGCAAGCAACAGCTAAATGAATTGGGCAGTGAATCTGCTAAGATAAAAGCCATGGGCATCACGAGCAGGGTAGGCAGTAACTCACTGTATACTACCACTTTTATGTTGTTGTTAAAAACCTCATGAAATCATACTCAAACATTTGCTAGCTTCAAACCCTTAATGCTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa1954
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000134510 | Essential Splice Site | 971 | 1189 | 24 | 28 |
| ENSDART00000141735 | None | None | 315 | None | 8 |
The following transcripts of ENSDARG00000093281 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 8330438)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 7531145 |
| GRCz11 | 5 | 8035783 |
KASP Assay ID:
554-1942.1 (used for ordering genotyping assays)
KASP Sequence:
TGGTCAAGCATGCTATGACTATGCAGCCCTACCTCACCACCAAGTGCAGT[G/T]TAAGTGCACGCTTCCTCTCTCCATCAGCACATGCYCAACTACCACTGTGA
Long Flanking Sequence:
GCAGAGCTTCGGCCCTCCAGGAATTGAGTTGGAAACCTATTTTGTAGAGGCTTTATGAATTTGCAAACAGAATAATACAGTAGGCAGCAAACATCTTAAACAACAACCCAAATGTTCCTAGAAGTCTTCACTTGTTGCTTTTTTCAAAGATGAGAGGGTGTTAGTTATTTATTAGTGTGTGCATATACGAGTGTGTGCGTTTATATGAATGAGTGTGTGTGTTTCTTGTTGCATTTCAGCAATTTGTTGATTAAAAGATTGAATAGGGAATGAATAAATGAATGCACGATAAAATCTTCAGAACAAGCTTGCCAATTTATTCTTGCTGGTTTCCTACTGATTGTGATTTTCTGTTGTGTGTGTGTGCAGAGCATAAAAGTGTGAACTCGACGCGGTTGGTGGCGTGCATCACCACGCTGTATCTGTTCAGTAAGATCAGAGCGCAGCTGATGGTCAAGCATGCTATGACTATGCAGCCCTACCTCACCACCAAGTGCAGT[G/T]TAAGTGCACGCTTCCTCTCTCCATCAGCACATGCTCAACTACCACTGTGATTTATATGATGCTATTCTGCCATCTAGTGGCTGTACACTCCTAGTGAATGGGCTATATGCACATGATATGACTTTTGTTCATTAACTTTGTTCAGTAAGACTCCATTTGTTTACATCAGTTAATTGAACTAAAGTCAATGTAATAACAACTGCGAACACACTTAATAATCTTAGTTGATCTTCATTTCTTAGTTAATGCCTAATAACGTAATAATACTAATAGTTTTTTTTTTGTTATCATACCTGTTAATGTACCTTTTTTGCAGCTTAGGTCAATATCGTGATGATTTTGTATATCATGATATAAAAGATTCAGCAATTAATCACAACATGAACATTTGATACCTGCAGAAGCCTAGCCTGGAGGTGTTCATTTATCTACTTTTCAGTGTTTATTCACGATGTGTTGTTTTTTTCTCCACAGTCTCAGAGTGACTTCATGGTGATTTG
Associated Phenotype:
Not determined