Busch Lab

ZMP

c6

Ensembl ID:
ENSDARG00000093052
ZFIN ID:
ZDB-GENE-040426-1358
Human Orthologue:
C6
Human Description:
complement component 6 [Source:HGNC Symbol;Acc:1339]
Mouse Orthologue:
C6
Mouse Description:
complement component 6 Gene [Source:MGI Symbol;Acc:MGI:88233]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa23911 Essential Splice Site Available for shipment Available now
sa37283 Nonsense Mutation detected in F1 DNA Not yet available
sa23910 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa23911
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000138553 Essential Splice Site 29 710 1 14
ENSDART00000139430 Essential Splice Site 49 855 2 18
ENSDART00000144861 Essential Splice Site 49 243 2 6
Genomic Location (Zv9):
Chromosome 21 (position 19660211)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 20795700
GRCz11 21 20832336
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGTCCCAATGCACTAAAACCTGTGATTCTGGTACTCAATCACGTTTAAG[G/A]TAACAATTATTGAGCATTTATCTGATGTGTAAAGCTTAATGTTGTGATGT
Long Flanking Sequence:
GCATGCTAGTAACATGCTAAATCAGATCTACTTTTTTTTTTTTACATTTTATATATACTTAAACATCCCATTCCTCAACCCTGATATCTGCTGACTTAAAGATGACAATATTTTTTTATTTTTTTATTATAAATTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACATAAACAATTTGCTTTCGTTAGCTAAAAGATTCATTCTAATGATTTGTGTTTGACTACAGACGCCAGTTGTTTATGTATGTCATTGGAAGTTTAACAAACTCTGTGTTCCCCTATAAGCTATCAATTTCCAACAGGCCGTCTTCTCTATGGATTGTACTTGCATTCTCCTTGCCCTACTCTCCACCCTGGCTTCTTTAAGTCCCACTATGGGGTGTTTCTGTGATCATTACCCATGGAGTTCCTGGTCCCAATGCACTAAAACCTGTGATTCTGGTACTCAATCACGTTTAAG[G/A]TAACAATTATTGAGCATTTATCTGATGTGTAAAGCTTAATGTTGTGATGTAAGTACATGTATTGTTGCAGGGCTGTCCAGTATGATGATCACTGGTTAAAAAACAGCTGTTCCCAGCTGTGTCAGATACATGATAATAGAGTGTGTAATGTTGAGGCCTGCCCTATAAACTGCCAGCTGACTGAGTTTGGACCCTGGTCTGAGTGTTCATCTTGTGCCAAAAAGTCAGTGAGTAAAACACACACACAGTTTAAAATGAGTTGCTCTGGGTGCTCACATAGTTTTCAGTGTTTGAGTTTTTGCATTCTATTGACCTTTTTCTTTCACATTCAAGAGGGTGCAGTCAATGGAACCTTACTGGCTCAAGACTCACATTGCAGATCTCATTCACATTCATTGATTTTTAGCTGTAAAAAAACAGCACAAAATTCAGCTTGATATTACAAACTCGTGTGTTGTTACTATGTGTAGTCATAAAATATGGTCATTTCTGCTATAGGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37283
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000138553 Nonsense 222 710 5 14
ENSDART00000139430 Nonsense 240 855 6 18
ENSDART00000144861 Nonsense 240 243 6 6
Genomic Location (Zv9):
Chromosome 21 (position 19652150)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 20787639
GRCz11 21 20824275
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAAACTAAAGAGGAACCTCTACAGAATCTCAGCCAACACTGAGAGATA[T/A]GAACTCAAGGTCAGAAAGAAATCATTTTATGCAAGTATTTGAGTTGTCTT
Long Flanking Sequence:
CTAGCAAGTTTGTACAGTCCTTCAATGCAGTGTTCTAGAAAACTTGGGACAACCAACTTGTTTTTTTTGCCACCAAAGGAAGATGTATACATGCTGATCTGCAATGCAACGATCAGAACGACTGTGGTGACAACTCTGATGAGAGAGACTGTGAGCGCAATAAAAGTGTGTGTTCAAATCAGCAGATGTATGCTTTCGTCCCTGGAGCAGACCAGATTGGTTTTGGGTGAGTTACAGATTGAGATCATTTACTTTCTGAGACCGCAAAACAGCTAAATGGAAAACATTTAGGGTGTTGTCAGCAAAGCATCTCTGGATATCAGAGAATGTGCTTGATTTAAAACTGATAATGATTAAAATTTTAATGATTAAATCAGATTTGATGCTGCAGCGGAGCAGATGAGAGGTGCTGTTCTGGACAACTCGTTCATGGGAAGTAATTGTACTGTAGAAAAACTAAAGAGGAACCTCTACAGAATCTCAGCCAACACTGAGAGATA[T/A]GAACTCAAGGTCAGAAAGAAATCATTTTATGCAAGTATTTGAGTTGTCTTTTATAATTTATTATTATAAAATTATAATTATCATTTTTGCTCTATTTAAACACATATTAACTAATATGGGTTATTTAATAAGAATTGCAAAAAATCTTTATTAATAGTTCTTATAAAGAATTTTAAAAGGAATAATTCATAGTGTTTTGAACAGTACATTCATCATCTTGCAGTGCCAAATTTGTGTAGGGGGAGCTATTTATTTAGCTTTTCACAGCAAAATAGCATAGATAAAAATTCATTTTATGCATTTATGTGAGCAATATCACATGAGTAGCAGTGCGATATGGTTACATATTGACACTGGTGGGAGGTGTGCGTTTATACAAAAATTTGACAGCGTAATCGTGTGTATAAAAAAGAAAATCAAACACGGGACAGTCTCAAAAACGCCTTTGTATGAGGAACTACTTTCTTACTTCACTCATTCAAATCTGCAGCTGATGTCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23910
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000138553 None None 710 None 14
ENSDART00000139430 Essential Splice Site 839 855 18 18
ENSDART00000144861 None None 243 None 6
Genomic Location (Zv9):
Chromosome 21 (position 19623703)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 20759192
GRCz11 21 20795828
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CATTATATTCAACTAAAATAATTCAACAGTCTTATTGTCTTTTCTTCTTA[G/A]TGTCCAAAACGTGTGAGTGTAAGATGCCCAGAGAATGTCCAAAAGACGGG
Long Flanking Sequence:
CCTGCTCTGTTAAACCTAATTTGGGAAATATTTAAAAAAGAAAAAAAATTCAAAAGGGGGCCAATAATTCTGACTTTAACTGTATATTAAAAATATAAGATCGCTGCTTTAATGCAGTGCTATTTGCAGTCATGACCATTTAACACTATGTATTTGTGTATCCTGCAGAGGCTACAGAGAAGACTTGTGCGTTTATGACGCTGGCAAGGAAACTGCCATTATGATGTCCCTCTGTGCTTTTCATGTTGACCGTTGTCATGGAGACAGATTATACTTTATGAATAATGGACCGTGCAAAAGTGACGCACGCAGTCTGGACTGGGCCAAATTCAGGGTCAGTGTATCTGAGCAGAGCTCGGTGCAGGAGCCCTGCGGTTCAGACACCTGTTACGAGTGGGAGACCTGCTCAGGTACAGACCGAATCACAAATCCTTACATAATGCATTCTTTCATTATATTCAACTAAAATAATTCAACAGTCTTATTGTCTTTTCTTCTTA[G/A]TGTCCAAAACGTGTGAGTGTAAGATGCCCAGAGAATGTCCAAAAGACGGGTAGAAAATATACTGCCTGAAAATCGTGGGAACGCAAACCACAAGAAGCATGAATCTGTGTTTTATGGCTGTAATGAAGTGCAGCAGTATAGAGTTTGAGCTTCAGAATGAAGGCCCTTGTGCAGGTTCTTAATTGTGCACCACTTTAGCTGTAAAAATGTTCACAGATTTGCAGCCATTATTGATTCATATTGATAACACATTGTCATTTTAAAATCACTCACAGCATGTTATAGTTATTTGATTGTGCATATGGGCATTCTTGATATTGATCTGGAACAACACAATAAAATATAATCGGACATTCAGATGCCTTCTAGTATTTAAATACTCTTTCATCTGTTAAAGTTGAATGTTAAAATAATTACTTTCTGGCATGTCAGAAATAACGTTTGAGGTTACAGAAGTAACCCTCGGGGAACGGAAGTGCTATAAGTGGATTTGATGTTAA
Associated Phenotype:
Not determined