Busch Lab

ZMP

LOC566845

Ensembl ID:
ENSDARG00000091260
Human Orthologue:
MYLK4
Human Description:
myosin light chain kinase family, member 4 [Source:HGNC Symbol;Acc:27972]
Mouse Orthologue:
Mylk4
Mouse Description:
myosin light chain kinase family, member 4 Gene [Source:MGI Symbol;Acc:MGI:3643758]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa17085 Nonsense Available for shipment Available now
sa32817 Nonsense Mutation detected in F1 DNA Not yet available
sa12023 Nonsense Available for shipment Available now
sa39738 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa39739 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa17085
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000122138 Nonsense 185 769 2 14
Genomic Location (Zv9):
Chromosome 2 (position 431465)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 398133
GRCz11 2 411000
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGCTGAAGGAACCCAAAGGTTTTCATCTGAGCCTCAAAGGCCTCAAAGCA[C/T]AGAGGAAGAAGAAACCACCAGATTCAGCTGGTAAGTACAAAAACAAAACA
Long Flanking Sequence:
CTCATTTAAATATCTAAAAATGCTTAACTCAAGTTTTTTGTTACACAAAGTGTTTTGTTTTTAGAAATAAGTGAGTTTTTTCTTAAAATAAACAAGCAAAATAATCTGCCAATGGGGGAAGTTAAATAATAATATTCCAAACCAAAAGCAAGATGATTGTCCTCCCCCCAGCATTGGCAGATTATTTTGCTCTCTTCATTTTGACTTATTATTTCTGAAAACAACACAATGTTGTGTGCTTGTCTAAAAAATTCTTCTTGATTTAATTTTTTAGATATTTGGACTAGAAACAAGACAATAACTCATATTTTGCAGTGTATATTCTCACAGCATTTCACAAGAGTTGCTTGCTGACTCTAAATGAATTGTACAAATTCGCTTCACATATGAAAGACCTGCAAGTTTATTTACTAAGGTGAAATGGTTTCCTCTGTTTCCTTTTTGATTTAAAGCTGAAGGAACCCAAAGGTTTTCATCTGAGCCTCAAAGGCCTCAAAGCA[C/T]AGAGGAAGAAGAAACCACCAGATTCAGCTGGTAAGTACAAAAACAAAACACACATACAAGATATAGCCTTGTTTTCAGAAATAATGAGTCAAAATGAAGTGCTTATTACTTTAAAACTAGCTAAATAATCTGCCAATAAGGTGAGTAAAATAATCCTGTTTTGTCTTTTTGACCCCTCTGACCCAATTGGCAGATTATTTAGCTTGTTTTAAGGGAAAACTCACTTAATATTGGCAAATTATTTCTTAAAACAAGACATTATGTTTTGCTTGTCAAGAAAAAGCTTCATGATTTGAAAATTAGTAGATATTTGGACTAGAAACAAGACTAAAAATCTAAGTATGAAAAGCACTTATTGCAGTGTGCCCCTGTATACACTTCTAGAGATTGTGAATTATGTACCCAGAGGTACGTATGGCTGCATTTTGTCTTTAAATCAAACGCTACTTGGGGCGTTTGCTTTTCGTGCTACCAGCTGCCCGCTTACCTCCATACAGACG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32817
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000122138 Nonsense 276 769 3 14
Genomic Location (Zv9):
Chromosome 2 (position 433163)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 399831
GRCz11 2 412698
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAAGAAGACGAAAGTAGAGAAAAAGGTGACTCTGGATCTCAGAGAAGAA[C/T]AGAAGAACATCCCAGAGACGAACACAGAGGAGATCCGAGAAGAAATGAAG
Long Flanking Sequence:
TGAGCCTGGGTTGTCATTGGCAGATTATTTTGCTTGTTTTAAGGAAAAACCGGCTTAATTTTGACTCATTATTTCTGAAAGCAAAACAATAGTTTGTACTTGTCTTGAAAATGCTTCTTAATTTAAGACTTTTAAGATGTTTAGACTAGAAACAAGACACAAACTCTGAATAATCAAAGCATTTTTGCAGTGTAGTCAGTATCAGAGTGTGCAACCCAGACAATACACTGAAACGCACGTGTTACGCTCATATTCCAGCAGACAAAGTCTTTCTGAGGAAGCAGGCACTGTTGCTTGAAGAAGTTCAGAAACTCAACCAGGAGAACGCCGAGCGCTCCAAACCAGCCCAGACTCAAGATAATGACCTGCAGAAATCAGAAGATGCCTCGGTTACTCCACATCTGCAGGACATTATCCTGGAGGAAGCCAAACCGGTGGAAGACGAGCCGAGAAAGAAGACGAAAGTAGAGAAAAAGGTGACTCTGGATCTCAGAGAAGAA[C/T]AGAAGAACATCCCAGAGACGAACACAGAGGAGATCCGAGAAGAAATGAAGAAAGCAGACACTGAGGAAATCCTGCTGAAGACCACAGAAGTGCTCAAAGATCAGAAAACAGACGATACGGAGAGCAAGACGACTACTGAGGGCCCTTCAGAAGCTGATAATATTGACACAAAAGCTACTGAGGGCCCTTCAGAAGATGTTATTACTGACAAAGAGACTATTGAGGGCCCTTCAGAAGCTGATATTACTGACACAGAGCCGCCAACAGCAACTGAGAACTCAGAAATAAGGTGAGCTTAAAGTCTGCATGAACTGTTGTTATTCTGTATTGTAGTTCCTGAGAAACTGAATATTAATGAGAAAAAAGTGGGCGTGGTTTGTTTTTATCTACTGCAAGCTGATTGGCTGTGGAAAAGTAGGCGTTTCATTCAGAGAGACGGGAAAAGGGTTTTTGGAGTTATTACAATCTAACAGACTCCTCCTCCTCCTCCTCACTATTTC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12023
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000122138 Nonsense 440 769 4 14
Genomic Location (Zv9):
Chromosome 2 (position 434057)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 400725
GRCz11 2 413592
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGTTTAAAGCYGACGGTGTGGAGATCCAGATCGACTTCAGCAAACTGAAG[C/T]AGCAGAGCTTTRAGGATGAAGATGATGAAGATCACGGCGATMACTTCTTC
Long Flanking Sequence:
AAGCTGATTGGCTGTGGAAAAGTAGGCGTTTCATTCAGAGAGACGGGAAAAGGGTTTTTGGAGTTATTACAATCTAACAGACTCCTCCTCCTCCTCCTCACTATTTCTGTTTGTTGTTATGGCGATGTCAAAACTGACAGTTTGAGGGGCGTGGTTATGTGTTAGCCACACCCAATACCTAACAAAGCCTGATTGACTGCAGTGGAATAGTTTAGTCAACTGACAACAGATCCAGTAATCCTGAGTTTGTTCATCCAGAGTAACAGTACAGGCCTCCTCTGTCGTGTCTGTGTTACAGCAGCGAGTCTGAACAGGCAGATGAAGTGACGACCAGCAGCAAGCGACGCGTGACGGAGGAAGATCTGGGTTTGGAGGACCATAAAAAGAGTCGCGTTGAGGACGGAGAACAGCAGGAGCCGGAGCCGCCGGAGCCTGAAGATCTGCGCGCTGTGTTTAAAGCCGACGGTGTGGAGATCCAGATCGACTTCAGCAAACTGAAG[C/T]AGCAGAGCTTTGAGGATGAAGATGATGAAGATCACGGCGATCACTTCTTCATTGGTGAGATTCTCATTTGAGTCCAATATATATAAGCTTGGCAGGGTGACTTTTAAAATTAGGATAGCAATCTTGCGATATGTCTTAAGGATGCTGGGAATTGTTTTTTATATATTGTTGTTACAGGAAAAGACGTTGTTTTAACAAGAATAAAATCTAATTTTCAAGAAAAGATGTAGTTTTAATGAGAAAATATCTTATTTAATGACATTATTACAAGAAAATTATGTGTAAACTAAATAATTATGTCGTTTTAACAACATATTTTATTACAAGTAAAAACATCCCGAAATTACAAGAAAATATGTTGTCTTAATGATGAAATATGTTGTTTTAGCAACGTAATATCTCCTTACTACGAGAGAAGAGGTTGTCTTAACGAGAAAAGATCTTGTTTTAGTGACATATCGTTATTACCAGAAAAGATGTTGTTTCAACAAGAAAATATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39738
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000122138 Essential Splice Site 675 769 11 14
Genomic Location (Zv9):
Chromosome 2 (position 443654)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 410070
GRCz11 2 422937
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTTCAGAGTAAATGGGTGTGTTTTTCAGTGTGTGTGTTGTGTGTTTTCT[A/G]GGCTCAGCGGTTTGTCGCCGTTCCTCGGGGACGACGATAACGAGACGCTG
Long Flanking Sequence:
TATGATTTTGTGTCCTTCAACACAGACATGTGGAGTTTGGGCGTCATCACGTACATGCTGTGAGTCTTGTGTGTGTGTGTGTGTGTGTGGAGGATAGTGAGTAAAATATGTTTATATTGGCTTCAGAGAAGCTTTAAAGCATAAAAAGTAATTTATTTTAAGCTTTAAACAATGAACAATACTAATACCAGCATTTATTGTTTACTATTTATTAAATTAATTAATAAATATCAGTTATAAATATATAATAGTAAAAATAAACCTTTTCTCATGCATTAATAAAACTAACATTAGTTAATGCACCGTGAGTTAACATGAACTGAGCTTATTTTCACTTAAAAATGTGAACAAATATGAATAAATCCTGTCATAAATGTGTTATTCATGGTTAGTTCATGTTAGTAAATGCGTGATCTAATCTGACCTGATCATTTCTCAGATTGACTAGTCATTTCAGAGTAAATGGGTGTGTTTTTCAGTGTGTGTGTTGTGTGTTTTCT[A/G]GGCTCAGCGGTTTGTCGCCGTTCCTCGGGGACGACGATAACGAGACGCTGAACAATATTCTGGCCTGTCAGTGGAACTTCGAGGAGGACGAATTCTCTGAAGTCTCAGCAGAAGCCAAAGATTTCATTTCCAAACTCCTGGTGGTGGATAAAAGGTAAACAGGAGGATAAAACACACATTAAAGGGACGTTTAGCTTTGTTTTTCTGCACTTGATGTGTGTGGAAAGAGTTGAGAAAGAGTCAAAGCAAAAACATTGTTTATTATAAATAGTGTCGATATTTATGAAGGTCAGCACAAGTTTGATAAATGCAGAGCCTAAAATATGAACAAAATGTGAGTATTTTATGTGAAACAGCATTACCTTTTATATTAATTCAATCACGTACTACATGCATTTAAAAACACATAAAACTGTTGTCAATAAAAGGGAGCGTTAGAAGAGTTTTGACATTCAAAAGCAAAGAAAAATATATGCAAAAAAAAAAAAAACGATATATAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa39739
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000122138 Nonsense 699 769 11 14
Genomic Location (Zv9):
Chromosome 2 (position 443728)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 410144
GRCz11 2 423011
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCGGGGACGACGATAACGAGACGCTGAACAATATTCTGGCCTGTCAGTG[G/A]AACTTCGAGGAGGACGAATTCTCTGAAGTCTCAGCAGAAGCCAAAGATTT
Long Flanking Sequence:
GTGTGTGTGTGTGTGGAGGATAGTGAGTAAAATATGTTTATATTGGCTTCAGAGAAGCTTTAAAGCATAAAAAGTAATTTATTTTAAGCTTTAAACAATGAACAATACTAATACCAGCATTTATTGTTTACTATTTATTAAATTAATTAATAAATATCAGTTATAAATATATAATAGTAAAAATAAACCTTTTCTCATGCATTAATAAAACTAACATTAGTTAATGCACCGTGAGTTAACATGAACTGAGCTTATTTTCACTTAAAAATGTGAACAAATATGAATAAATCCTGTCATAAATGTGTTATTCATGGTTAGTTCATGTTAGTAAATGCGTGATCTAATCTGACCTGATCATTTCTCAGATTGACTAGTCATTTCAGAGTAAATGGGTGTGTTTTTCAGTGTGTGTGTTGTGTGTTTTCTAGGCTCAGCGGTTTGTCGCCGTTCCTCGGGGACGACGATAACGAGACGCTGAACAATATTCTGGCCTGTCAGTG[G/A]AACTTCGAGGAGGACGAATTCTCTGAAGTCTCAGCAGAAGCCAAAGATTTCATTTCCAAACTCCTGGTGGTGGATAAAAGGTAAACAGGAGGATAAAACACACATTAAAGGGACGTTTAGCTTTGTTTTTCTGCACTTGATGTGTGTGGAAAGAGTTGAGAAAGAGTCAAAGCAAAAACATTGTTTATTATAAATAGTGTCGATATTTATGAAGGTCAGCACAAGTTTGATAAATGCAGAGCCTAAAATATGAACAAAATGTGAGTATTTTATGTGAAACAGCATTACCTTTTATATTAATTCAATCACGTACTACATGCATTTAAAAACACATAAAACTGTTGTCAATAAAAGGGAGCGTTAGAAGAGTTTTGACATTCAAAAGCAAAGAAAAATATATGCAAAAAAAAAAAAAACGATATATATATATATAATATAATATAATATAATATAAAATATATATTGCATTACATAATATAATGTATTAATTTTCTTGTTCC
Associated Phenotype:
Not determined