Busch Lab

ZMP

si:dkey-21o19.2

Ensembl ID:
ENSDARG00000088900
ZFIN ID:
ZDB-GENE-090313-241
Human Orthologue:
PLEKHG3
Human Description:
pleckstrin homology domain containing, family G (with RhoGef domain) member 3 [Source:HGNC Symbol;Ac
Mouse Orthologue:
Plekhg3
Mouse Description:
pleckstrin homology domain containing, family G (with RhoGef domain) member 3 Gene [Source:MGI Symbo

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa24324 Nonsense Available for shipment Available now
sa14419 Nonsense Available for shipment Available now
sa37697 Essential Splice Site Available for shipment Available now
sa15459 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa24324
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000128986 Nonsense 173 387 6 12
ENSDART00000144478 None None 159 None 5
Genomic Location (Zv9):
Chromosome 23 (position 24410069)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 24196635
GRCz11 23 24123186
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACAGGGTATTCTTCCTCTCTCAGCCATTGAAGTGCATCTGATCCCACAG[C/T]AGGACTCCAGTTCGCCACATATGTTTGAGATTAGTGGTAAGAGCCTCTCT
Long Flanking Sequence:
TAAAAATATGATGCATAAATGTTGACCTAATCATTTACTTGCTCATTCTGAATTATCCTCAAAGCCACCAACTACTTTTAAATAACTGTTTTTGTAAATAATAAAGGAAAATTGACTAACAATGTATAAAAATACAATCATTAAGCACATTATATATGTGCTTATAAGCCAAGAATACAGCTTTTGTGGCTGTATTTATAAACTGTTTGCTAATATTAATGTAGAGTTAATACTTAAGACAGGATGAACTGTTTGATAATGCTTAATAAAGAATTTGTAGTGTGCAGTTATTATAAAATGTAAAAAAATTTAATAGTTCTTCAAAGAGACATTTATTGGAAAAAAAAAACATTTCTGAAACTTTTGTGCACTCACTGGAAAGGTCATATGGAACCTTGTGTATATGAGCATTGGGAAATATCTGTGTCTAGAGTTATTTCTGTGTTTTGTCACAGGGTATTCTTCCTCTCTCAGCCATTGAAGTGCATCTGATCCCACAG[C/T]AGGACTCCAGTTCGCCACATATGTTTGAGATTAGTGGTAAGAGCCTCTCTGAGGGGAAGAAACTAAGCTTAAATCTCTAAACTGAACTTGAATATGACAACTTTGAAATCACAAAAACTATTTAATCATCATAAACCTGTATTTATGATGCACTATAGGACCCATGGTGGACTCGAAGATCTTCATTTGTGCTGGTGCTGCTGAAACAAAAGCCTGGATGGAGAACATTGAGGACAGGCGATACAAGTCTGTAAGACAACAGCTGAGCCCGTCTCATAGTGCTCTCTCATACCTGGTAATTACCGTAGCCTTAATTTACAAGTGCGAGATTAACTAATTTTGAATACATGATATAGAAAATGTAGTTAGCAAGATGCAACCAATATATTACCTATTATCATTGATTGCATTTTGATTACTTTTAGTCTATGACATTGATTTTAATAGGAAAATCTTGAGAAAAATAAGAAGAAAAAAAGTAACAAAACAAAATACAAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14419
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000128986 Nonsense 254 387 8 12
ENSDART00000144478 Nonsense 26 159 1 5
Genomic Location (Zv9):
Chromosome 23 (position 24411642)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 24198208
GRCz11 23 24124759
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAAAAGGAGGAGCTGAAAAGATACTTGCTGCGGTCTCCCATCATGCAATG[G/A]GAAGGAGTCCCCATTCAGCACATGGGACATCCAAGATACCTCTCACTGGT
Long Flanking Sequence:
GTGCTGTAACAAATAAAAGCATGTCTGAAAACATGGCCACCTTTTAATTATTAAGTAAAAATCAGTCTCTAAATGTCAACATTTTCGTTTTATATTTACCATAGATGCACTGTCAATAAATAGCCAAGCATTAGCCAAAAGTTGCAATTCCACAGCATTTCAGGTGGTCTCAATTTTCTTCCATAGCTGACATAACTGTAAAACATTACATAGCTGCTTTAAATTGTTAATTGGTAACCTAAAAACCTTCTGAGTCATTTAAACATAAATTACAATATAAACTGACTTCAAAACATTTTAATAAACATGCTAAACTTAGACATTTGTTTTCATTACTTACTGTTTTATGCAATGTTCTTTACTTAATGAAAAATGTGAAGCAGACTGATTTCATACCATTGCTCAGATGTTTTATTTTCACCACTCCAGGTGCCGTGTGATGAAAACTGGAAAAAGGAGGAGCTGAAAAGATACTTGCTGCGGTCTCCCATCATGCAATG[G/A]GAAGGAGTCCCCATTCAGCACATGGGACATCCAAGATACCTCTCACTGGTGCACATCAGCAACGTATATGCAAAGGTCAGCATACAGATGATAAAATACAGAGTGGTATCCATGTAATTCAGGATGGTACTAAATATACCTATTTTTAAACAACAGAGCCGGCATTTGCAGGGACCTCAGGAGCGTTTGCTTGTGCTCTTTCCAAGTGACCTGCTCATTCTGTCTCTCGATTGCCATCGCATACGTGTGAAATATGAGGTGAGCTCATTTTGCTGACTTAACAACAAACTCTGCAAGAACACTGCACTATCAGCAATCCTATATGTATGTGGTGAACCATATTTGATTGAAAAGATAACTTGGTAAAAAAAAAGTGCTGACAGTGCACTTTAAAACATTCAGTTTCTTTAAGAAACGACTGCATTTTAAGGCACTTTTATGAAAGACCTTCAGGCCAGAATCACTATCACTTGACCTCAGCTTAAAGGGGTGGTCCAGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa37697
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000128986 Essential Splice Site 339 387 11 12
ENSDART00000144478 Essential Splice Site 111 159 4 5
Genomic Location (Zv9):
Chromosome 23 (position 24416399)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 24202965
GRCz11 23 24129516
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATCTTCATGTTTTATGCTGATTTATGCCGACGATGAGTGATGTATTTTCC[A/T]GGTGAACTGATGGAGCCTCTGCTTGTCTCCTGTATTTACCCTGAGGACTA
Long Flanking Sequence:
AGATCAGTCTTTTCATTATGACCGGCCATGTGAAGACAAGAAATACTCTTGCATAACATTAACCCATTAGGGTAGCTTTAACTTTACTGGGGTAGGATATAATCCTACAGTATATTGGATATTGAGGTAGGATATAGTGTAAGATCTTTCATAAACATTAAGAGTGCCATATTTGCATACATTGCTTGTTTTGCTGTTTTAAAATTCAGAAACTAAGTGATGTTAGTCATAAAACTTGTGAATCACCTTCAGAAAATAGCAACGGGATGATAAACTTACTAGCTTCTCAATGTTCCTCTTATCAGCTACATTCTGTTGTAACTGTTAAAGATGCAAGTCATTTAAAATGCCAGTACACTTTTAAGTTTTCAGGCTTTTTTGTATAAATGCTAAAAGTGACAGTTCATGCAGGTCACTTTCTCTGTGTTCTCTAAACTGCTGTACAGTACAATCTTCATGTTTTATGCTGATTTATGCCGACGATGAGTGATGTATTTTCC[A/T]GGTGAACTGATGGAGCCTCTGCTTGTCTCCTGTATTTACCCTGAGGACTATCAAAGCTGGATCTTCCAGTTACAACAGGCAAGACTGCAGTTTTTGGATTTCCTCGACACCGCTTTCAACTTAAAACAGAAAACCTTTAATGTATTTTGACCATTCATTCATTCATTCATTCATACAATAATGGCATTTTTAACGCTTAAATGATTATGAAAAGTACATCGAGTGTGCAATTTTTTACTAAGCTTTTTCTGTGGTGTTCATACAGTATCACTAAACCAAATATATTCATTTTAATGACATCTAATGTATCTAGTAGTCCAATAAATTGCACTCTATGAGTCTAGCTTGACTTTTATACAGATAATGCATATTTATATGATTATAGAAGCATATTTTTCAAGAAAAAATGTCTTGAACACTCATTGTTTGTAGATATGCTGCTTTTTGACCATTTACCTAATGTTTTCCTGCATCCCTGCTGAGCATGTTAAAACATTATT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15459
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000128986 Nonsense 363 387 11 12
ENSDART00000144478 Nonsense 135 159 4 5
Genomic Location (Zv9):
Chromosome 23 (position 24416472)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 24203038
GRCz11 23 24129589
KASP Assay ID:
2261-7719.1 (used for ordering genotyping assays)
KASP Sequence:
TTGTCTCCTGTATTTACCCTGAGGACTATCAAAGCYGGWTCTTCCAGTTA[C/T]AACAGGCAAGACTGCAGTKTTTGGATTTCCTCGACACCRCTTTCAACTTA
Long Flanking Sequence:
AGCTTTAACTTTACTGGGGTAGGATATAATCCTACAGTATATTGGATATTGAGGTAGGATATAGTGTAAGATCTTTCATAAACATTAAGAGTGCCATATTTGCATACATTGCTTGTTTTGCTGTTTTAAAATTCAGAAACTAAGTGATGTTAGTCATAAAACTTGTGAATCACCTTCAGAAAATAGCAACGGGATGATAAACTTACTAGCTTCTCAATGTTCCTCTTATCAGCTACATTCTGTTGTAACTGTTAAAGATGCAAGTCATTTAAAATGCCAGTACACTTTTAAGTTTTCAGGCTTTTTTGTATAAATGCTAAAAGTGACAGTTCATGCAGGTCACTTTCTCTGTGTTCTCTAAACTGCTGTACAGTACAATCTTCATGTTTTATGCTGATTTATGCCGACGATGAGTGATGTATTTTCCAGGTGAACTGATGGAGCCTCTGCTTGTCTCCTGTATTTACCCTGAGGACTATCAAAGCTGGATCTTCCAGTTA[C/T]AACAGGCAAGACTGCAGTTTTTGGATTTCCTCGACACCGCTTTCAACTTAAAACAGAAAACCTTTAATGTATTTTGACCATTCATTCATTCATTCATTCATACAATAATGGCATTTTTAACGCTTAAATGATTATGAAAAGTACATCGAGTGTGCAATTTTTTACTAAGCTTTTTCTGTGGTGTTCATACAGTATCACTAAACCAAATATATTCATTTTAATGACATCTAATGTATCTAGTAGTCCAATAAATTGCACTCTATGAGTCTAGCTTGACTTTTATACAGATAATGCATATTTATATGATTATAGAAGCATATTTTTCAAGAAAAAATGTCTTGAACACTCATTGTTTGTAGATATGCTGCTTTTTGACCATTTACCTAATGTTTTCCTGCATCCCTGCTGAGCATGTTAAAACATTATTGGCAGTCACATTTATATTTGTTTTAACTTATTCTTGCTTTTATTATAATAATTTTATTATTTAATATACTGAT
Associated Phenotype:
Not determined