Busch Lab

ZMP

MCC

Ensembl ID:
ENSDARG00000087450
Description:
mutated in colorectal cancers [Source:HGNC Symbol;Acc:6935]
Human Orthologue:
MCC
Human Description:
mutated in colorectal cancers [Source:HGNC Symbol;Acc:6935]
Mouse Orthologue:
Mcc
Mouse Description:
mutated in colorectal cancers Gene [Source:MGI Symbol;Acc:MGI:96930]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa5275 Splice Site, Nonsense F2 line generated Not yet available

Mutation Details

This allele has been removed from public view.

Allele Name:
sa26376
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000128214 Nonsense 255 770 5 19
Genomic Location (Zv9):
Chromosome 5 (position 589790)
Other Location(s):
Assembly Chromosome Position
GRCz10 KN150702.1 26102
GRCz11 5 1709103
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTCCAGGTCGTCTGACTCCTGCTGGACGCCCCATAAACCCCAGCACTGGA[G/T]AACTCAGCACCAGCAGCAGCAGCAACGACATCCCCATCGCCAAAGTACAC
Long Flanking Sequence:
TATATATCTTATTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCGTGCGTGTGCGTGAGAGAAAGAGAAAGAGAACTGTTTGTGTGTGTGTAAATGTGTGTGTGTGAGAGAGAGAGAAAGGTGAGTGCGCGTGCGTGCGTGTCTGTGCGTATGAGCAAGCATGTGTTTGTGTGTGTGTGTGGTGTATTTGAATGAGTGTGTGTGATGTTCTGCTGTCTGTAATAGAGCTGAACTGAAGCCACATCAATGTAAGCATCTGCTCCTCTGATCTATGAGTGCACACTGTCTTATTGCCTTGTGTGTGTGTGTGTAGGTGCGAGAGATGCAGACTCGTCTCCAAAGTGTTCAACCCGGCGCTCCGCCCAGTCCAGGTCGTCTGACTCCTGCTGGACGCCCCATAAACCCCAGCACTGGA[G/T]AACTCAGCACCAGCAGCAGCAGCAACGACATCCCCATCGCCAAAGTACACACTAACTGATCACACACACATACACACACATGATCACACACACTGATCACACACACATACACTGTAGCATTGATTTTTGTTTCATGTCATCTTACTTTATTTTACTTTACTTTGCCTTTTTTATTTTATTTTTTTATATTTTATATTTATTTTATTAAATTAAATTTTATTTATTTTATTAAACTTTATTTTATTTATTTTAATTTGTTTTATTTTATTAAATTTTATTTTAATTTATTTTATTTTATTACATTTTATTTAATTTTATTTATTTAATGTATTTTATTTATTAATTTTAAATTATTTTATTTAATTACATTTTATATTATTTACCCATTTATTCAATAGGTTGAGTGTCTTGATCAAAGGCTTAGTACTGACAGCACATTTTATTCAATTTATTATAATTTTAATTTATTTATAATTTTATTTCTTGTTTTTATGTTTAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa5275
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Splice Site, Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000128214 Splice Site, Nonsense 397 770 10 19
Genomic Location (Zv9):
Chromosome 5 (position 595667)
Other Location(s):
Assembly Chromosome Position
GRCz10 KN150702.1 31979
GRCz11 5 1703226
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCTGTGTGTGAGTGTGTGTGTGTGTGTGTATGTATATATAGTTAAAGAGT[C/T]AAGTTAAAGAGAAATATGTGAGAAACAATGTGATGAAGATGTTCATGTTG
Long Flanking Sequence:
ACTTAGACAGTCACTTACCTGTTTTATAATGATTTGATCAGCTGTAGTTTGAAATTTATCTAGAGTTTTTCCTTCTCTAAGCACTTATTATGCGGTCTCTGTCGCCATCCTGTGGAGGAACATCAACCATCTTTGCTCTGCTCAGCATGACAGGTTGATGGCCATCACAGTCACCGTCCTTATAAATAAACTGCATAGCTGCAATCTAAACAACTACATTCTCAACTAAATAAAGCCTCAAAGGTACATGATGTTGTCCAACAGCTGCAATATTTGTCAAACTGTAGTGAGTTTATTGATCTGCTGTTGCTCTATGTGGGCGGAGTAATACACAAGGGTGAAGAGGCTGAACGAGTGCTGATATTGTAGAGTATTGCATGGCTATCAGCCAATTAGATTTGAGAACAAAACAGAACTGTGTGTGTGCGTATGTGTGTGTGTGTCTGTCTGTCTGTGTGTGAGTGTGTGTGTGTGTGTGTATGTATATATAGTTAAAGAGT[C/T]AAGTTAAAGAGAAATATGTGAGAAACAATGTGATGAAGATGTTCATGTTGACTCCTGTTATTGATCATGTGCTATTGTTATTGATCTGCTATTGTCAACTCTGTCAGAGCAACAGAGGAGTGATGAAGAGTGTGTGTTTGTGTTTGTGTTTGTGTTTGTGTTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTGCAGTGAGCAGTGTATTGAGGCCTATGAGCTGCTGTTGGCTCTGGCTGAGAGTGAACAGGGTCTGGTGTTGGGTCAGTTCAGAGCAGCTGGAGTCAGTGCTGTGGGTAAGAGAACACACACACACACACACACACACACACCACTAAAGGATGACATATTATAGCAGGGGTCTCAAACTCAAATTGGCTGGGGCCATTTCAGTGACTGACGATACATAGGAGGGCTGCTTTAACATTCAAGCACAAGAAGAAAGTGTAAACCTGATGTAGCTGATG
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa26377
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000128214 Nonsense 708 770 17 19
Genomic Location (Zv9):
Chromosome 5 (position 626393)
Other Location(s):
Assembly Chromosome Position
GRCz10 KN150702.1 62705
GRCz11 5 1672509
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAGTGAAGTCCGGCATCAGCAGTCAGCAGAGTTCGTTAATGACCTCAAA[C/T]GAGCAAACAGGTGCAAAAACACACACACACACACACACACACACACACAC
Long Flanking Sequence:
ATATTCTTCAAGACACTTCTATACAGCTTAAAGTGACATTGAAAGGCTTCACAAGGTTATTTAGGGTAAAGTTAGGGTAATTAGGCAAGTCACTGTATAACAGTGGTTTGTTCTGGAGACAATCCAAAACTAATATTGCTGAAGGGGCGAATAATATTGACCTTAAAATGGGTTTAAAACAATTAAAAACTGCTTTTATTCTAGCCGAAATAAAACAAATAAGACTTTCTCCAGAAGAAAAAATATTAGAGGAAATACTGTGAACAACTCCTGAATCTGTTCAACATCATTTGTGAAACATTTGAAGAAAAAAAGCAAGAAATCACAGGAGGATGATGAATTAAGACCTAAACTGTACATGCATATGTGTATGTGTGTGTGTGTGCAGAGAGAAGAAGCTGAAGGCTCGTGTTCAGGAGCTGGTCTCTGCGCTGGAGAGATTGACCAAGAGCAGTGAAGTCCGGCATCAGCAGTCAGCAGAGTTCGTTAATGACCTCAAA[C/T]GAGCAAACAGGTGCAAAAACACACACACACACACACACACACACACACACACACACACACTACATCCTTATCATCATCAACATCATCACTAAGCCTGAGTGGCGCCTCCTGCTGGACACACAGCACTACAACATACAAACACTTGAGCTGTGAAGAAAGAACATCAGCTTTAGGCATTTAAATATTTAGTTGCTAAAGAATCTTCATTCATTTTCTTGTTGGCTTAGTCCCTTTATTAATCCGGGGTCGCCACAGCGGAATGAACTGCCAACTTAATAAGTTTTTATGCAGCTTTTGCCCTTCCAGCCGCAACCCATCTCTGGGAATCATACACACACACATACTCATACACTACGGACAATTTAGCATACCCAATTCACCTGTACCACATGTGTTTGGACTGTGGGGGAAACCGGAGCACCCAGAGGAAACCCACGCGAATGCAGGGAGAACATGCAAACTCAGAAACGCCAACTGAGCCGAGGATCGACTAAAGAATC
Associated Phenotype:
Not determined