Busch Lab

ZMP

CHRNA4 (3 of 3)

Ensembl ID:
ENSDARG00000087071
Description:
cholinergic receptor, nicotinic, alpha 4 [Source:HGNC Symbol;Acc:1958]
Human Orthologue:
CHRNA4
Human Description:
cholinergic receptor, nicotinic, alpha 4 [Source:HGNC Symbol;Acc:1958]
Mouse Orthologue:
Chrna4
Mouse Description:
cholinergic receptor, nicotinic, alpha polypeptide 4 Gene [Source:MGI Symbol;Acc:MGI:87888]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa45269 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa15204 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa45269
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000127176 Essential Splice Site 64 551 2 8
Genomic Location (Zv9):
Chromosome 6 (position 58411395)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58514523
GRCz11 6 58508754
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTGGTTCACGTTCACTTCGGTCTGTCCATCGCTCAGCTCATCGACGTGG[T/A]ATAATCCGCAAACACCTTCTGAAGAGATTGCAAATCCCAACACCATCATT
Long Flanking Sequence:
ACATTGCAATGTTGTGCATCTGAGCTTGTCGCTGAAACCGTAAACACTTTGCTTTTTCATTGTTTTGATGGATTTACGAACATTTCAGCCATCGATGGAGAAACTGGAGTGAAGAAAAGGTGCTTTTGAAAGTTTTCAGGACCAAAACAACAGTGATAAACAGATCCAGGACGCCATCTTCATCATGTTTTTCTGTCTTCATCTTCTGCTGCTTCTTTATCCGGCTCAAGGTAAAACACAGCAGGAATGCCAATGCAGGCTATAGACAGTATCATTAACCTGGACAATGGAAGTCTACAGTATATAATGTCCTCATTAAGATAGTGAAACAAACCTGTGTGTGTGTGTGTGTTTAGTGTGCTGTGATGAAGTCCAGGCTGAAGAGCGTCTGCTGAACTCTCTGCTCTCAGCATACAGTAAACTGACCCGTCCGGTTCACAGTGTCTCTGATGTGGTTCACGTTCACTTCGGTCTGTCCATCGCTCAGCTCATCGACGTGG[T/A]ATAATCCGCAAACACCTTCTGAAGAGATTGCAAATCCCAACACCATCATTTATTACAGCCTAGGCTCAGTGTAAATAAATGCCTGAGCCTGCATTATTGCAGAACATTAAAGACGCTACTTGGGGTGTGTTGCATGACACGTTTCAGATGACAAATCCAGTAGAGGGCGCTGTCTACATTTTTGCAAATCTGATATACGTGTATTTTGTTGCATAGCTTTAAGTATGTTTTTGAGAATTTTCAAAACGTTAGACAAAGGTAGACTAATGGTACAGCATGTTTAACAGATTACCAAACCAACCGTTATTGTGATAAACTATAAAACTCTATCTTATATCTTCACCAGGATGAGAAAAATCAAATGATGACCACTAATGTGTGGGTGAAGCAGGTGAGTGTTAAACTCTGCGGACCCGGTCCGTGACGTCATCGACTTTCGCTTTCAGATTTATAGGGCTAGCGTTGCACCAGGCCCCCGTAAGTGGTGTCGTTAGAAAGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15204
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000127176 Nonsense 145 551 7 8
Genomic Location (Zv9):
Chromosome 6 (position 58419170)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 58522298
GRCz11 6 58516529
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCTCACCTTTTMCATGACGGAAGAGTAANNNNNNNNCCTCCGGCCATCTA[T/G]AAAAGCTCCWGCAGCATYGRYGTCACCTTCYTCCCCTTCGACCAGCAGAA
Long Flanking Sequence:
GAGCCCATACAATATATCTGATCTAAATTTTTTGTAAAACAATAGCTTTGTGTTGAGGCAATCGTGTGAGAAGCATCTTTCTCCACTGATTCAGGGTGCTGCAAATCATTAAAAATACTTTAATGTTTTCAAGGTTTTGAAAGTGCTTAGATTTTGAATAAAGGGCTATACTGTAGAATATATCAAATAGCATCTGACATAATGTGAAGTTATGTAAGTGTGTAACTTGCCACACTTGTAAAGTGCTAGAAAGTTTTGAAGATGAATCTGAAAAGTGCTTGAAATGTACTTAAATTTGATTATGTAAGAACCTTTTAAGAAGCTCTGTACACTTATAAAACAATTTATTTGCCTCAAAATGTTATTTCACACAATCAGAAGTAAGACTAAAGAGCAACACTGTGTTTCTGCAGTGCAGATGGTGATTTCACAGTGACGCACCTGACTAAAGCTCACCTTTTACATGACGGAAGAGTAACCTGGATCCCTCCGGCCATCTA[T/G]AAAAGCTCCTGCAGCATCGATGTCACCTTCCTCCCCTTCGACCAGCAGAACTGCACCATAAAGTTCGGCTCCTGGACGTACGACCGCAGCAAAATCGATCTGATCCGCATTGCAGACAGTGTAGACCAGCTGGACTACTGGGAGAGCGGAGAATGGCTCATAACCAGCGCTGTCGCCACATATAATGTGAAGAAATACGAATGCTGCTCTGAGGAATATGCAGACATCACTTATTCCTTCATTATCAGACGACTGCCGCTCTTCTACACCATCAATCTCATCATCCCATGTCTACTTATTTTATGTCTAACTGTATTGGTTTTCTACCTCCCGTCTGATTGCGGAGAAGAAGTCACCATGTGCATATCTGTGCTGCTTTCACTCACAGTCTTCCTCTTGCTGATCACAGAAATCATCCCGCCGACCTCATTGGTGATTCCTCTGATTGCAGAATACCTGCTTTTCATCATGATTTTCATCATACTTTTCATAATAATCAC
Associated Phenotype:
Not determined