Busch Lab

ZMP

si:ch211-244c8.3

Ensembl ID:
ENSDARG00000079889
ZFIN ID:
ZDB-GENE-091118-9
Human Orthologue:
PHLDB2
Human Description:
pleckstrin homology-like domain, family B, member 2 [Source:HGNC Symbol;Acc:29573]
Mouse Orthologue:
Phldb2
Mouse Description:
pleckstrin homology-like domain, family B, member 2 Gene [Source:MGI Symbol;Acc:MGI:2444981]

Alleles

There are 3 alleles of this gene:

Allele Name Consequence Status Availability
sa16842 Nonsense Available for shipment Available now
sa24883 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa16842
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109705 Nonsense 106 1026 2 16
ENSDART00000131984 Nonsense 189 1197 3 18
Genomic Location (Zv9):
Chromosome 10 (position 36515783)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 35548485
GRCz11 10 35492345
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCCACCACTTTCAATACGAGTCCCTTCCCCTTACTCACCCTCCAGTAGTT[T/A]GAGCATGCCGCCATCTCCCCACCAATCAGAGCGCCCTATAAGTCCAGTCC
Long Flanking Sequence:
ATATATATATATATATATATGTATATGTATATATATATATATGTATATATATGTATGTGTGTGTGTGTGTGTGTATACACATAGTAGGCTCTTTTCTTTATTAAAACTTTAACAATTTTTTTTTTGTTCAAACTTGCCTATATAGTAATGTGTCTTGGTAAAAACACATATACAGTTGAAGTCAGAATTATAAGCCCCCCTTTGAATTTTTTTTAATTGAATATATATATTTTTTCCAGATACAACAAAGTTCCATTCCAATGGCGGCTCATTGGTTGGATCCAGCCTCCGCGGCACACGGTCCAAGGCAGAGCTTCAGGAGTTGATGGAGAGCCTGCAGCGGAGGAAATCTGCTCTGGAGGCCAGCTTAAAGGCTACTGCTGACCGTGGGTACCTCACATTATCTCCACCTCCCAGCCCACAGTCGGCTTCTTCCTATCTACAGGACCGTCCACCACTTTCAATACGAGTCCCTTCCCCTTACTCACCCTCCAGTAGTT[T/A]GAGCATGCCGCCATCTCCCCACCAATCAGAGCGCCCTATAAGTCCAGTCCCAAACCAAACCCGTGCCAGACACCAATCGCAGGACAGCCTGTTGCTTTGCCACTCTTCAGAAGGGCGGCATCCCAACTCTTCAAACCCACTCTTAACTATGTGGAATGGCTCTTCATCCTCCTACGGGAACGATGCTCTTCTTTCATCTCGCAGAGGTCCAAGCGGGGCGGCCAGCATGCCCTCCAGCCCTCGTTTGGGGCGCCGTTTGTTAGCACGAGATGGCGAGTCCCCCATTGAACCATCACTTCGCCAAAGAAAATACTCCACCGGCTCTTTGAATGGCCTGGGCGGACATAGTCGCTCTCTGCCCCGGTTGTATCGAGGAGACGCCCCAATGCTGTCTTTGCCACCCCGACGTACCACCAAACCACGGCGCAGCTTTCCATCCATGGAGAAGCCTCCAGATGTGACTGTGATTGCCAATGTGAACAGCAGCTCACGGAGGGCCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24883
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109705 Essential Splice Site 878 1026 13 16
ENSDART00000131984 Essential Splice Site 1029 1197 15 18
Genomic Location (Zv9):
Chromosome 10 (position 36544311)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 35577013
GRCz11 10 35520873
KASP Assay ID:
554-7476.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAGACTGCAGGAGGAGACCAGCAGAAGACAGAAACTAGTGGAGAGAGAG[G/A]TGAAGATACCAGACTAACCTGTTTATAGTTGCTCTAATTCAAACATTTTA
Long Flanking Sequence:
TGCCTTTAAGTAGCCCAGATATAAACACTTCCTGTCTGTGGAATTTTGATTGCATTCCGAGCTCGTTCCAGTTCCTGAGCCTTAAGATGCTCTGGAATAAATGGAGGGATTTTATTGGACAATGCATTATTTTTATGTGCATAGGAAAAGCATCAAGTTTCACCAAGCGTGTGCATGTGTGTGTGTGGTCTATGTAGCGCCAGCACAGCTAATATGGCAAAGATAGAGGAGATGGAGCGCATGCTGAGAGAAGCTCAAGCTGAGAAGCACAGGCTGCTGGAGCACAGGGTACATTTGGTTGTTTTTAGTTTTTTTTTTTTTTAATACAGCGATTTCAATATGCAGACGCATGAACAAGGAGCAATGTTTTTATTCTTCTGCAGGAGCGAGACATGGAGCTGCGCAGACAGGCTCTGGAGGACGAGAGGAGAAGAAGAGAAGAGCTGGAGAGAAGACTGCAGGAGGAGACCAGCAGAAGACAGAAACTAGTGGAGAGAGAG[G/A]TGAAGATACCAGACTAACCTGTTTATAGTTGCTCTAATTCAAACATTTTAAATACACAGAGTTATAATACAGTTAGAGGCAAAATTATTAGCCCTCCTGTGAAATCTTTATCAATTATTTCCCAAATGATGTTTAACAGAGCAAGGAATTTTTCACAGCATTTGCTATAATATTTTTTCTCCTGGAGAAAGTCTTATTTGGTTTTGTTCAACTAAATTCAACTAAATTTTAATTTTCAATGGTCTACAAATAAAACCATCCTTGTACAATGATTTGCCTCATTACCCTCTCTAACTTGCCTGATTAATCTAGTTAAGCCTTTAAATTGCACTTTAAGCTGAATACTAGTGTCTTTTGAAAAATATCTAGTAAAACATCATGTACTGTCGTCATGGCAAAAATAAAATTATCTGTTATTAGAAATGAGTTAATAAAACTATTATGATTAGAAATGTGTTTGAAAAAAGGAGAAAGGCTAATAACTGTAGTTACCTTCATCT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa27648
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109705 None None 1026 None 16
ENSDART00000131984 Nonsense 1031 1197 16 18
Genomic Location (Zv9):
Chromosome 10 (position 36546513)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 35579215
GRCz11 10 35523075
KASP Assay ID:
2260-3504.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATAATGAATTATACTTAACAAATGTGCATGCATGTATTCACACAGACATA[C/A]AGTCTTATTCGTAAGCGAGAGTTGATTAGATCTGTGCTGTTTGTGTGTGT
Long Flanking Sequence:
TATATATATATATATATATATATATATATATATATATATATATATATATATATATACATACATATATATATATATATATATATATATATATATATATATATATATATATATATTATTATTATTATTATTATGTTTTTCATATTAAAAGTAGAAAATAAGCAGCATCTCTTCTAAATAAATTAACTCTTGTATATCCTGTAAATAATATTTTAAACATTGCATTTCTTGCATCTTCTGTAAACAAATATTTTATTGTAAATAATAATTTTATTGTAACAGAAAATATTATAGCCATAATATAATATAGCTGATTAACGGCTATTCATTTGATAAAAAATTATTTTATAAAAAATCAGCTTATTAAAGCAAAAAAATCAGCTTATAAAAATCAGCTTATTTATCATGTGGCTGATAAATCAGTATATGCAGTAATGTATTCTAATACAAATGATAATGAATTATACTTAACAAATGTGCATGCATGTATTCACACAGACATA[C/A]AGTCTTATTCGTAAGCGAGAGTTGATTAGATCTGTGCTGTTTGTGTGTGTCCAGTCTCGTCCGCTGACTCGGTATCTGCCGGTAAGGAAGGATGAATTCGACCTGCGAGGACACATCGAGGCGGCCGGACACCATCCAGAGACCTGCTTTCATCTGGCCATCACTGAGAAGACCTGCAGGGGCTTCCTGGTCAAGATGGGAGGCAAAATCAAAACCTGGAAGAAGCGCTGGTTCGTCTTTGACCGTAATCGTCGGACACTGGCATATTATGCTGGTAATTACACTGTAATTATTCAGTAAAGCTTAATAATCAATGTCAATGAAAAAGCTCAGATTTTTAAATGAAAATCCATTATAAATTATACTATGAATAACTCCATTATATATATATATACATATATATATATATATATATATACATACATACATACATACATATATACATACATATATACACACACACACACACACACACATAGATATATACATATATATACTGT
Associated Phenotype:
Not determined