ZMP

si:ch211-244c8.3

Ensembl ID:

ENSDARG00000079889

ZFIN ID:

ZDB-GENE-091118-9

Human Orthologue:

PHLDB2

Human Description:

pleckstrin homology-like domain, family B, member 2 [Source:HGNC Symbol;Acc:29573]

Mouse Orthologue:

Phldb2

Mouse Description:

pleckstrin homology-like domain, family B, member 2 Gene [Source:MGI Symbol;Acc:MGI:2444981]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa16842	Nonsense	Available for shipment	Available now
sa24883	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa16842

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000109705	Nonsense	106	1026	2	16
ENSDART00000131984	Nonsense	189	1197	3	18

Genomic Location (Zv9):

Chromosome 10 (position 36515783)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	35548485
GRCz11	10	35492345

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TCCACCACTTTCAATACGAGTCCCTTCCCCTTACTCACCCTCCAGTAGTT[T/A]GAGCATGCCGCCATCTCCCCACCAATCAGAGCGCCCTATAAGTCCAGTCC

Long Flanking Sequence:

ATATATATATATATATATATGTATATGTATATATATATATATGTATATATATGTATGTGTGTGTGTGTGTGTGTATACACATAGTAGGCTCTTTTCTTTATTAAAACTTTAACAATTTTTTTTTTGTTCAAACTTGCCTATATAGTAATGTGTCTTGGTAAAAACACATATACAGTTGAAGTCAGAATTATAAGCCCCCCTTTGAATTTTTTTTAATTGAATATATATATTTTTTCCAGATACAACAAAGTTCCATTCCAATGGCGGCTCATTGGTTGGATCCAGCCTCCGCGGCACACGGTCCAAGGCAGAGCTTCAGGAGTTGATGGAGAGCCTGCAGCGGAGGAAATCTGCTCTGGAGGCCAGCTTAAAGGCTACTGCTGACCGTGGGTACCTCACATTATCTCCACCTCCCAGCCCACAGTCGGCTTCTTCCTATCTACAGGACCGTCCACCACTTTCAATACGAGTCCCTTCCCCTTACTCACCCTCCAGTAGTT[T/A]GAGCATGCCGCCATCTCCCCACCAATCAGAGCGCCCTATAAGTCCAGTCCCAAACCAAACCCGTGCCAGACACCAATCGCAGGACAGCCTGTTGCTTTGCCACTCTTCAGAAGGGCGGCATCCCAACTCTTCAAACCCACTCTTAACTATGTGGAATGGCTCTTCATCCTCCTACGGGAACGATGCTCTTCTTTCATCTCGCAGAGGTCCAAGCGGGGCGGCCAGCATGCCCTCCAGCCCTCGTTTGGGGCGCCGTTTGTTAGCACGAGATGGCGAGTCCCCCATTGAACCATCACTTCGCCAAAGAAAATACTCCACCGGCTCTTTGAATGGCCTGGGCGGACATAGTCGCTCTCTGCCCCGGTTGTATCGAGGAGACGCCCCAATGCTGTCTTTGCCACCCCGACGTACCACCAAACCACGGCGCAGCTTTCCATCCATGGAGAAGCCTCCAGATGTGACTGTGATTGCCAATGTGAACAGCAGCTCACGGAGGGCCA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa24883

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000109705	Essential Splice Site	878	1026	13	16
ENSDART00000131984	Essential Splice Site	1029	1197	15	18

Genomic Location (Zv9):

Chromosome 10 (position 36544311)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	35577013
GRCz11	10	35520873

KASP Assay ID:

554-7476.1 (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GAAGACTGCAGGAGGAGACCAGCAGAAGACAGAAACTAGTGGAGAGAGAG[G/A]TGAAGATACCAGACTAACCTGTTTATAGTTGCTCTAATTCAAACATTTTA

Long Flanking Sequence:

TGCCTTTAAGTAGCCCAGATATAAACACTTCCTGTCTGTGGAATTTTGATTGCATTCCGAGCTCGTTCCAGTTCCTGAGCCTTAAGATGCTCTGGAATAAATGGAGGGATTTTATTGGACAATGCATTATTTTTATGTGCATAGGAAAAGCATCAAGTTTCACCAAGCGTGTGCATGTGTGTGTGTGGTCTATGTAGCGCCAGCACAGCTAATATGGCAAAGATAGAGGAGATGGAGCGCATGCTGAGAGAAGCTCAAGCTGAGAAGCACAGGCTGCTGGAGCACAGGGTACATTTGGTTGTTTTTAGTTTTTTTTTTTTTTAATACAGCGATTTCAATATGCAGACGCATGAACAAGGAGCAATGTTTTTATTCTTCTGCAGGAGCGAGACATGGAGCTGCGCAGACAGGCTCTGGAGGACGAGAGGAGAAGAAGAGAAGAGCTGGAGAGAAGACTGCAGGAGGAGACCAGCAGAAGACAGAAACTAGTGGAGAGAGAG[G/A]TGAAGATACCAGACTAACCTGTTTATAGTTGCTCTAATTCAAACATTTTAAATACACAGAGTTATAATACAGTTAGAGGCAAAATTATTAGCCCTCCTGTGAAATCTTTATCAATTATTTCCCAAATGATGTTTAACAGAGCAAGGAATTTTTCACAGCATTTGCTATAATATTTTTTCTCCTGGAGAAAGTCTTATTTGGTTTTGTTCAACTAAATTCAACTAAATTTTAATTTTCAATGGTCTACAAATAAAACCATCCTTGTACAATGATTTGCCTCATTACCCTCTCTAACTTGCCTGATTAATCTAGTTAAGCCTTTAAATTGCACTTTAAGCTGAATACTAGTGTCTTTTGAAAAATATCTAGTAAAACATCATGTACTGTCGTCATGGCAAAAATAAAATTATCTGTTATTAGAAATGAGTTAATAAAACTATTATGATTAGAAATGTGTTTGAAAAAAGGAGAAAGGCTAATAACTGTAGTTACCTTCATCT

Associated Phenotype:

Not determined