Busch Lab

ZMP

LOC562316

Ensembl ID:
ENSDARG00000079862
Human Orthologue:
KL
Human Description:
klotho [Source:HGNC Symbol;Acc:6344]
Mouse Orthologue:
Kl
Mouse Description:
klotho Gene [Source:MGI Symbol;Acc:MGI:1101771]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa12515 Nonsense Available for shipment Available now
sa18644 Nonsense Available for shipment Available now
sa41699 Nonsense Mutation detected in F1 DNA Not yet available
sa41700 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa12515
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114703 Nonsense 7 970 1 5
Genomic Location (Zv9):
Chromosome 10 (position 35039061)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 34066919
GRCz11 10 34010779
KASP Assay ID:
2260-3462.1 (used for ordering genotyping assays)
KASP Sequence:
TSGTTTTGTTCTGTCAATTTCAGGGCACAGCATCTGATCCAGGAGCAGGA[C/T]AGCACACATGGGACACATTCAGCAAACTTCCATATCCCGACGACAAAGCC
Long Flanking Sequence:
GTTTGTTCATTCAAAGTCACTGAATAACCAGTTTAGGTTACAGGATAACTAGGTGATCAGTATCACTGTAATATACAGTTCAATAATATTTATATATATATATATTTATACATATATATTCAGTCTTTAAAGAAATTAAGTTGTCATTAGGGTCCATTTTCTTATCATTGCTGTTGTTGTCATCGTATAATCATATTTGTCGTATCATACTCTAGCAGGAGGAAATCTGTTATATTATGGAGGCCGGAATTGCGCAGTGCTTGGATACCTATTTACCCGTCAAGTGCCTGGGTAATAATTGATAGATTTCCTGAGAGGACAACAACAAAAAAAAAACGGGCCCAGATGGGTTACACCACAGTGAGGTAAGAGATTCAGCTCACTCCTTTAACATTTACAACACAGTCCAGTTCTCTGACACCATGAAAGTGACATGGATTCCTCTGCCGCTCGTTTTGTTCTGTCAATTTCAGGGCACAGCATCTGATCCAGGAGCAGGA[C/T]AGCACACATGGGACACATTCAGCAAACTTCCATATCCCGACGACAAAGCCTTCCTCTATGACACCTTTCCTGATAAGTTTATGTGGGCCGTCGGCACCGCTGCATATTCAGTGGAAGGAGCCTGGGAAAAAGACGGGAAGGGTAAGTCAATCTGGGACACTTTTACTCGAGGAGGGACCCGAGTGTCCAGAGGAGACGTTGGTAGCGATAGTTATCATAACATCCCTGGAGACCTTCGAGCTCTTCAGCAACTAGGAGTCAGTCATTATCGGTTCTCCTTGTCCTGGCCACGCATTTTCTCCAATGGCACTAAGGAAAGCTACAACGACAAAGGTGTGGAGTATTATAAAAATCTGATCCGGGGTTTGAAGGACATTAAGGTGCAGCCTGTTGTCACTTTGTATCATTGGGACCTGCCTGACAGTTTGCAGACGCTCTTTGGAGGCTGGAGTAATTCGGTTATGGTGGAGCTGTTCAGAGACTATGCCGATTTTTGCTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18644
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114703 Nonsense 286 970 2 5
Genomic Location (Zv9):
Chromosome 10 (position 35042398)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 34070256
GRCz11 10 34014116
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACTTTGTGCTTGGCTGGTTYGCCCGTCCCTTGTTTGTAGATGGAGATTA[T/A]CCACCCTGCATGAARRACAATCTGACCCACAGACTGCCGTCCTTCACCGA
Long Flanking Sequence:
GGTAATTAGGCAAATCATTGTATAACCATGGTTTGTTCTGTAGACAATCAAAAAAAAAATACTGCTTAAGGGGGCAAATATTGACCTTAAATTGTTTTTTAAAAAATTAAAAACTGCTTTTATTCTAGTCGAAATAATACAAAAAAACTTTCCCAAGAAGAAAAAACATCATAGGAAATACTGTGAAAATTTTTTTGCTCATCATTTGGGAAATATTTAAAAAAGATAATTATAGAAATAATAAATTTGACTTTAACTGTATATACTGTACATATACATAACAAAAACATGTTTTCAATTGTATTCTAGGCTCACGCTGCAGCCTGGCACCTGTATGACGAGCGATATCGTGCCGCTCAGGGTGGGAGAGTGTCCATGGCTCTGGGATCTCACTGGATCAAACCCAGCAGAACCAGACAGGAGAGCCGCAAAGCCTGCCAGCGCTCTCTAAACTTTGTGCTTGGCTGGTTCGCCCGTCCCTTGTTTGTAGATGGAGATTA[T/A]CCACCCTGCATGAAGGACAATCTGACCCACAGACTGCCGTCCTTCACCGAGGCCGAGAGCGCGTATGTGAACGGAACCGCCGACTTCTTTGCTCTGTCTCATGGACCTGCTCTTAGTTTTCAGCTGATCAATGACAGTCTGCGCTTCGGCCAGACTGAAGATTTGGGTCTGAGGATGCTTTTGTACTGGGTCCGTGCAGAGTACAACAATCCTCCCATCTTTGTGGTGGAGAGCGGCTGGTATGGAAGTGGCAACACTAAAACAAAGGATGCCAAGCATATGTACTATTTAAAGCGCTTCATTATGGAGACGCTAAAAGGTATGTGGATGAATGAGGGGGTTTAATGATATTGTGAGGGTTTATTTGATGTTTAAGGGTTGGTTTGTGTCAGTGGTGGAAGGAGTATTGAAAAATCATACTTAAGTCAAGTCAAGCTTTATTGTCATTCTGCTACATGTGTTGACATACAGAGGAATGAAATGTTGTGTCTTGCAGGACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41699
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114703 Nonsense 415 970 3 5
Genomic Location (Zv9):
Chromosome 10 (position 35044287)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 34072145
GRCz11 10 34016005
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGAATGTGATTGGCTACACGGCCTGGTCTCTGCTGGATGGATATGAGTG[G/A]TACCGTGAATATGCGATACGCAGAGGGCTGTTCTATGTGGATTTCAACAC
Long Flanking Sequence:
GAAGTTAAAAACCATGAAGTTATATTTGAATTGTTGAATCATTAACTGAAAATAAATATGATTAGTTGTACAAGATGTTAGATTTCTATATTTGGTATTATCAGCAACAGTAGCAAAGGTCATTTTTTGTAATGAATATTTTCCATTTTCAGCTGTTTCTTTCTTGATTTTTATTTTTTTATTAAAATTACAGGTTCTACGTTCTGTTTGTTAAAACCAATTGGTTTTTGCTGTAATGTATTTGTATAAATGGAAACCAAATGACATTTGTCTCCTCCCCTTTTTTTGCTGATCCGAAAAATGATTTGATCCGTGACTCAAAAACCATAGTGTGATTCGACACAGTAAGATGTGTAGTCTGTTACATCAGTACTGTTTTTAACAATTCAGATTTCAAAGTCAATCATCAACATACATTTTCTTGTCTTTCCAGCAATCCATGTTGACAGGGTGAATGTGATTGGCTACACGGCCTGGTCTCTGCTGGATGGATATGAGTG[G/A]TACCGTGAATATGCGATACGCAGAGGGCTGTTCTATGTGGATTTCAACACTCCTGATCTGAAGAGAGAGCCGAAGGCATCTGCCACTTTCTATAGCAAACTCATAGAGAAGAATGGCTTCCCTCAGCTGCCAGAGAACCGCCCTGCACAAGGTGCATTTCCCTGTGACTTTGCTTGGGGAGTGGCTGCCAACTCCATACAGGTACAACTTTCCCTGCTTATCACGTTTAAAGGTGCTCTAAGTAAATTTTGCCAAATTAAAAGGAGTGGGATCATCACTATACTCTACCTGACAAAAGTCTTGTTGTCGATCCCAGTTGTAAAGGCAACAAATAATTACTTGACTTCTAGTTGATCGTTTGAAAAAGTGGCAGAAGGTCGATTTTTTTTTTTTTTTTCCAATGAATCATCTGTTGAACTGCATCACAATCATCACAAATACTGCAGAAGACCTATTGAAACTTGGAAGTTTTTTTAATAAAAAATCATGGTTTGGGGTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41700
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114703 Nonsense 731 970 4 5
Genomic Location (Zv9):
Chromosome 10 (position 35047049)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 34074907
GRCz11 10 34018767
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCATTTTCGGTAAAGGCGATTACCCGGCGGTGATGCGTAGCTGGCTCCAA[C/T]AGAGGAACACTATTGATCTTTTCAACTACCACTTACCTACGTTCAGCGAA
Long Flanking Sequence:
AAACATTGCTAAGATACTATTATTGTTTTGTCAGCGAGCTACAAAAAGTGAACATAACCCCTGTGGTGACTCTTTGGCACCATACAGGGAAACTGTCCAGCCTTCCAGCACCAATGGAGGCCAGTGATGGCTGGCAGAGCGAGAAGACCGTCCAGGCCTTTGTGGACTATGCTAGGTTGTGTTTCCAACGACTAGGAGCTCATGTCAAGCTCTGGATCACACTCAATGAGCCCAACGATGAGGATCTTGAATACACTGTAGGTCACCAGCTGCTACGTGCACATGCTCTAGCTTGGCACGTCTACGACAGAGAATTCCGCAAGGCCCAAGGTGGCAAAGCATCACTGGTTCTTCATATGGATTGGGTCGAACCTGCATTTTCATTCAACAGGGAGGACGTGGCCCCTGCAGACCGAGTCCTGGACTTTCGAGTGGGATGGTTTGCGGAGCCCATTTTCGGTAAAGGCGATTACCCGGCGGTGATGCGTAGCTGGCTCCAA[C/T]AGAGGAACACTATTGATCTTTTCAACTACCACTTACCTACGTTCAGCGAAGAGGATCGGCTGTTGGTGAAAGGAACCTACGATTTCTTCGCCATCAGCCATTTTACTACCTCGATGGTGTACGATGGAGTGGAGGATAAATACACCTTTAAGGACAAGCTGCAGGTTCAGCTGATATCTGACGTGACCTGGATCATGTCCCCAAGACGCAACTCTCCTGTGGTTCCCTGGGGTCTACGCAAGGCATTGAACTGGGTGAACTCGCGATACAAAGGTGTTCCCATTTACGTGATGGCCAATGGTGTTCAAGAGGATACCGCTAGGTTTAGGGATAGCTTGCGCAGCTATTACCTTTACAACTATGTGAATGAGGCCTTGAAAGGTAAGAAATCATTTGTGTTGGCTTCCAGTAAAGTAGTTCATGCCGATCCCAATTTTTGAAAATGTTTGTGGTTATAGTTTATTGACCTTATTCTAAAATGCGGAAGTTTTCGCGATTGT
Associated Phenotype:
Not determined