ZMP

helq

Ensembl ID:

ENSDARG00000079818

ZFIN ID:

ZDB-GENE-060503-421

Description:

Novel protein similar to vertebrate DNA helicase HEL308 (HEL308) [Source:UniProtKB/TrEMBL;Acc:Q1LVP8

Human Orthologue:

HELQ

Human Description:

helicase, POLQ-like [Source:HGNC Symbol;Acc:18536]

Mouse Orthologue:

Helq

Mouse Description:

helicase, POLQ-like Gene [Source:MGI Symbol;Acc:MGI:2176740]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa6669	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa23901	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa6669

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000109412	Essential Splice Site	259	1010	3	18
ENSDART00000147372	None	1	711	1	15

Genomic Location (Zv9):

Chromosome 21 (position 18149308)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	19297560
GRCz11	21	19334196

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

TTTATTCAAATTTTGGTTTTGTAAGTANNTTTTTTTATTTGCTTTTRATTTC[A/G]GAGTGGCAGAAGACYTGTTTGAGCCTGGATTCAATTCAGCAGAGGAGAAA

Long Flanking Sequence:

GAGTCCATAACATCTGAGGGAGACCTGGGTCCCTTTTTTGGCCTTCCGTCCAAAGTTAAAGATCTTATTTTTAGATTAAAGGGAATCCAGGACTTGTATGGTAAGTATTTAATGGCATGCTATGTCAGATGGCTTGGTGTCCTTATCAAATGAAATGTACAACATTAATTTCATAATATACCTTAAAAGCTTTTTTATTGCAAGTAAAGTTTTTTTTGAAAGCTTGTAAAAAAAAAAAGTTGAAATATAGCTGAAGTAATGTTCCATTTGATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACATATATAATACAAAATAAATATACACAGTGCGTTATATTGTAAAAAAAAAAAAAACTTTTATTTTGGATGCGATTAATCTTTGCTTAGCACTCATAATAAGTACATTATTAAATTTTATTCAAATTTTGGTTTTGTAAGTATTTTTTTATTTGCTTTTGATTTC[A/G]GAGTGGCAGAAGACCTGTTTGAGCCTGGATTCAATTCAGCAGAGGAGAAATCTTATTTATTCGCTACCTACAAGTGGAGGAAAGACTCTAGTGGCAGAGATTCTCATATTTAAAGAGCTCTTGTGTAGAAAGAAAGATGCACTACTTATTTTGCCGTACATATCCTTAGTTCAGGAAAAGGTATGTATTCATGCATGATTTATTTATTATCTAAACAAAATAATAATAATAATTTGGCCAGTGGGCTTTACGCACAGCTAGAGTTTTGAAGCCAATGATAAACTTCTGGTGAAAGCTTAATGTGACTATTTTCAATTTTACAAGGTTGTTTTTACAGCATCGATGCTGTAATAAAATTAAAATACATTCAGTTAAATAGACATAAGCATTGATTTAGTTGTTCAGATGTAAAACGGGATGAAAGACCGTGTAACCACTAGTGCCATCAGTAGCAACAGGCTATAGCAGAAATTCCATTAAAATACTGGGGTAAAATAAAC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa23901

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000109412	Nonsense	943	1010	17	18
ENSDART00000147372	Nonsense	644	711	14	15

Genomic Location (Zv9):

Chromosome 21 (position 18160883)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	21	19309135
GRCz11	21	19345771

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

GTGTGCTCATTTTGTTTTTTATTCTCTTTTGATTATAGCATCGTGCTAAG[C/T]AGCTGTACAGTGCCGGATACAAGACATTATCACATCTGGCCAATGCAGAT

Long Flanking Sequence:

CATCAGACACATAAAACCTATATATACTATTTTCTGTAGAAACCACTGTTGTCTAATGACTTGCCTAGTCAAACTAATTAACCTAATTAAGCCTTTAAATTGCGTAATTAAATACGTTAAATTAGTTATTATAAATAAGTTATTAAAACAATTATGTTTAAAACATGTTGAAAAAAAATTATGATTTTAATAATAATTTGTCTTCAACTGTATGTGTATCAGCTGTATTTTTTGTATGTGTTATAAATTTAATTGGATACTAAATCAAGTTTGTCTGGTCATTTCAGGAGCTGGAGGAGTTTTGGGCATACAAAGCTCTTCTCTCTGAGTTGACCCGAAGATTGACTTACTGTGTGCAGGCCGAGCTCATTCCTCTCATGGAGGTGTCTGGAGTCCTGGAGGTAAGTGTAGAGTATTTATGACCAGAATATTTGCTTGAATGTTATATTTGTGTGCTCATTTTGTTTTTTATTCTCTTTTGATTATAGCATCGTGCTAAG[C/T]AGCTGTACAGTGCCGGATACAAGACATTATCACATCTGGCCAATGCAGATCCACAAACTCTGGTCCAAACTATTGAAAACCTCTTTAAGAAACAAGCGTATCAAATTATTGCATCTGCAAAAGTAAGTATTGTATTGCATTATACCAAAGTCTCTTTAAGGCAAGTCATTTCACTCGCTGGCCATCTTTGAAATGCCTGTCTAAATAGGGAAACATCAAATTTACCGAAAGCAAGCTTATGATTGCATTTCATATTTGAAATCACCAATAAAATTAAACAACAACTGTCTTATAAGTTTCGTTTCTAAACATTAGAAACACACAAAATCGGCATACTTTCAGGTTGCCCAAGCTAATGCACATGCGCACTCGAAAGGAACGAGATCACGACACCAACCTTATTTATGGCCGTGTTACACATTATCATTATCTGAATAATGATCATCAGATTGCTCTTCTGCTCGTCTGACGTAATCCACAACTTGGTCTTGGTGGTGAAT

Associated Phenotype:

Not determined