Busch Lab

ZMP

si:ch211-120p12.3

Ensembl ID:
ENSDARG00000079473
ZFIN ID:
ZDB-GENE-090312-24
Description:
Novel protein similar to vertebrate mixed lineage kinase 4 (KIAA1804) [Source:UniProtKB/TrEMBL;Acc:B
Human Orthologue:
RP5-862P8.2
Human Description:
Mitogen-activated protein kinase kinase kinase MLK4 [Source:UniProtKB/Swiss-Prot;Acc:Q5TCX8]
Mouse Orthologue:
BC021891
Mouse Description:
cDNA sequence BC021891 Gene [Source:MGI Symbol;Acc:MGI:2385307]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa38936 Nonsense Mutation detected in F1 DNA Not yet available
sa42194 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa31928 Nonsense Available for shipment Available now
sa31927 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa38936
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110070 Nonsense 521 1017 6 11
ENSDART00000144282 Nonsense 498 959 6 10
Genomic Location (Zv9):
Chromosome 13 (position 23869446)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 23515106
GRCz11 13 23645556
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTTTCAGCACAAAATCACAGTTCAGGCCTCTCCTACGATGGACAAGAGA[C/T]GAAGTCTCAATAGCACAAACTCAAGCCCTCCCAGCAGCCCGACTCTGATC
Long Flanking Sequence:
AATATCAGATGAATTTATTTCAGTAAATTGGTGAAATAAAGAGTTAATCCTGACACATTCTATTTCACAAGTAACAGCATTTCATACTGCTCATAATTTACCCTAGGTCAGCAAATAGTCTTGAGCATTCATAGACTGGCCTTTCACACTTTATATTTATAAACCCTGTCCTATCGTCCTTCTATCGTCCGTTCTTTATTTTCAGCACACAGGTTGCTAACCCCACCTTCTATATTTCAAGTGAAATTTGTTGCAGTTAAAATTGGCAAAATGATAATCCAAGGTTAAGCAAAAAATGAAAGACCCAATTGTTTTGCATCACTTTATTGTTTTTCACTGGAGCATTAAGTGTGATGTAAAAACTTGTTATTGTAAAGTGTTGGAAGAAAATTTGGAAGAAATGTTTACAGTGGTATTAGTAAATACTAATCTTAGGTGTATATATAAAAGATTTTCAGCACAAAATCACAGTTCAGGCCTCTCCTACGATGGACAAGAGA[C/T]GAAGTCTCAATAGCACAAACTCAAGCCCTCCCAGCAGCCCGACTCTGATCCCTCGCCTCCGTGCTATTCAATGTGAGTACCCACTCTTCTACACTCTTTACCATTTTTTCATAACTGTATATGTGAGATTTTAATTAACCCTTAATAGCTTGATATGCAAGTTAAAAATAAATATATTTTAACCTTTTAGAATTGAAATTCATTCAAATCTAAGAAATGTTTGAGTATAATTTTTCTGTTGTTGAGTATCGTATTTTATTTAGGTTATGGGATATATAGTAAACATGAATCTAATTAATTTAAAGGTCCAAAAGGTAAGATGAATTTCTGATAGCTTATAAAACAGAAAAACACAACTTGCAAAAAAAAAAAGCAAATAAATATTAGTTGTTACTCCTATCACAAAAGAGCCTGTTTTTTTAAACCATTGTTGAGTTGTTTAATTTTGGATAATGCAATGTAATTTCTTAAAACTTGATTTTTTATATTTTAACAGGGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa42194
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110070 Essential Splice Site 544 1017 6 11
ENSDART00000144282 Essential Splice Site 521 959 6 10
Genomic Location (Zv9):
Chromosome 13 (position 23869373)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 23515033
GRCz11 13 23645483
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGCCCTCCCAGCAGCCCGACTCTGATCCCTCGCCTCCGTGCTATTCAAT[G/T]TGAGTACCCACTCTTCTACACTCTTTACCATTTTTTCATAACTGTATATG
Long Flanking Sequence:
ACAGCATTTCATACTGCTCATAATTTACCCTAGGTCAGCAAATAGTCTTGAGCATTCATAGACTGGCCTTTCACACTTTATATTTATAAACCCTGTCCTATCGTCCTTCTATCGTCCGTTCTTTATTTTCAGCACACAGGTTGCTAACCCCACCTTCTATATTTCAAGTGAAATTTGTTGCAGTTAAAATTGGCAAAATGATAATCCAAGGTTAAGCAAAAAATGAAAGACCCAATTGTTTTGCATCACTTTATTGTTTTTCACTGGAGCATTAAGTGTGATGTAAAAACTTGTTATTGTAAAGTGTTGGAAGAAAATTTGGAAGAAATGTTTACAGTGGTATTAGTAAATACTAATCTTAGGTGTATATATAAAAGATTTTCAGCACAAAATCACAGTTCAGGCCTCTCCTACGATGGACAAGAGACGAAGTCTCAATAGCACAAACTCAAGCCCTCCCAGCAGCCCGACTCTGATCCCTCGCCTCCGTGCTATTCAAT[G/T]TGAGTACCCACTCTTCTACACTCTTTACCATTTTTTCATAACTGTATATGTGAGATTTTAATTAACCCTTAATAGCTTGATATGCAAGTTAAAAATAAATATATTTTAACCTTTTAGAATTGAAATTCATTCAAATCTAAGAAATGTTTGAGTATAATTTTTCTGTTGTTGAGTATCGTATTTTATTTAGGTTATGGGATATATAGTAAACATGAATCTAATTAATTTAAAGGTCCAAAAGGTAAGATGAATTTCTGATAGCTTATAAAACAGAAAAACACAACTTGCAAAAAAAAAAAGCAAATAAATATTAGTTGTTACTCCTATCACAAAAGAGCCTGTTTTTTTAAACCATTGTTGAGTTGTTTAATTTTGGATAATGCAATGTAATTTCTTAAAACTTGATTTTTTATATTTTAACAGGGCTCGAAATTGCGACCATTTTGGTCGGATATGCGCCCAAAATTTTGTCTATGCGACCTCAAAACATATTTGGGAGC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31928
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110070 Nonsense 704 1017 10 11
ENSDART00000144282 Nonsense 646 959 9 10
Genomic Location (Zv9):
Chromosome 13 (position 23862808)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 23508468
GRCz11 13 23638918
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTATATCGATCTACCTCTGTGGAAAGATGAACCAGGCGAGAACCAGAGTT[C/A]AACAGGAGGAGGAGCTGAGAGCCAGGAGGACCCAACCACCTCCACCAGCT
Long Flanking Sequence:
AGTGTGCAGAGATTTTTGAACACATTGCTTTGAACACACATCTTTTTGAACACACATAAATTTATACACTTTTTCCACAAACACTTGAAATTAATTTAAATAAATAGTTAAAAGGAATAATAGAAAACATTTACTTAACTTTAAGGTTTAAGTTTTTCATGTTGAGCACAAATTAAGATAATTTCTTGAGAACCTGTAACCACTGATTTCCTTTTTAGGAAAAATATGCTAAGAAATATTATTGTAGTATGTCTTTGACACCATTGTGTGTATAGAAGTATGTAATTAAAGTCTGTGATGATGGTTCCAAAATGGGAAAGCAGATTTAAACTGATCTGCTGATCAACTGACGCACTGGCATTTCCCCCCCTCAGGGACCAATAAAGATGAAGCAGGCTCTGCTGATTCATCCGACAACAAACCAAAGCAACTCAAGTTCCCCAACCAGGTGTATATCGATCTACCTCTGTGGAAAGATGAACCAGGCGAGAACCAGAGTT[C/A]AACAGGAGGAGGAGCTGAGAGCCAGGAGGACCCAACCACCTCCACCAGCTCCACCAGCACCACCCCACAGCACACACCCACCAACAGCCTGAAGCGCAGCACCACCCGCCGCCGCACTGACTCTGTTCTCTACGGCTGTGCCTCAATCCTGGCATCTGTCGCATTCGGCTTTGACCTGCAAGAGATCTGTAAGAACCCTGCCAATGAAGAACCTGAGCCTCGTGAGGAGAAGAAGAAAAAAGAAGGCCTGTTTCAGCGCGCCACTCGCTTCCGCCGCAGCACCAGCCCTCCAGGCGGACGTTCGCGAAAAGATGAGATTTCCACAGCACCCGTAAACCTGCTCGCCATGTCATCCATTTCTGAGTGCAACTCCACCAAGTGCCTCCTGCAGTCAGATTTTGAGGGTCCTGGGTTTAACCTGGTTAACGAGACTGGCATTTCGCCTCAGAGTAATGGTACTGGTGAAGGACTGCACTTAACACCTGTACAAGAGCTCTCTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31927
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110070 Nonsense 921 1017 11 11
ENSDART00000144282 Nonsense 863 959 10 10
Genomic Location (Zv9):
Chromosome 13 (position 23859231)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 23504891
GRCz11 13 23635341
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTACCACTTCTACAAAGAAGAAGGCTGACAAAGAGCCTCCTCAAGACAAG[C/T]AGACCTCTGGGGAATCAGTATCTCGACCCAGACCGCTTTCCCTCAGAGGC
Long Flanking Sequence:
AATAATGTAAGCATAAATGCAGAATTATAGCCAATATTTCAATCCAGATGTTTCTTTTTCGTACCAACATCAATATATATTTCAAAACTTGTCATTTTTTTGTCCAATAAAATGCCAAAAAAGGTACAACACTTTGAAAATTGTATCTAAAATCTAGATTATTTAAACTGTATGGTGCAATGTTGTGAGATTTACATTTACTTGTGGCATTTTTATTTTTTAGATTTTATCAGTGTTTTATATGAAGGTTTAAAATATCTAGCTATCTCTCTATCTATTTATCTATCTGTAGGGCGGTAGGTAGATGGGTAGGTAGATAGATGACATATCACTGTACCCTTTCATTACTGCATTAAACTGATTTTTAAGTTCTCAATTGTTGTTTACTGACTTCTCATTTTGCTTTAGTCAATGGAAGCAGCAACTCTCCAGTCAGTCCAGCTGATTCTTCTACCACTTCTACAAAGAAGAAGGCTGACAAAGAGCCTCCTCAAGACAAG[C/T]AGACCTCTGGGGAATCAGTATCTCGACCCAGACCGCTTTCCCTCAGAGGCAAATCTCATTCCTGGAGTCTTCTGAAGAGTCGCAATAAGAGCTATTCTCTGGGACACTACTCTGGGGAGAAGAGTGTCCAAAACCTGGACATGCTGCTCCCTGCTGAGGTCAAAACCGGCTGCTCATTACTGGACATGGACACAGAGGGTCAAAAACGAGACTGCACCGTTCCCCTCTGCCGGATACAGAGCACACCAAGTCGGGGGTCTGTATTCGAACTGGAGAAACAGTTTTTATCCTGAAATAAGCTGCATCTGGAACACAATCCTGTATTTGTTTAGAGTCTGCCTGTTCAACGTAACATTTGTTTTTGTCCACGATTTAAGGGATAGTTCACCCAAAAATGAAAACTGCTGTTAATTTGCTTACTTCAGACATTTCGGATGCTGTTAGTGTTAGTTGAATTAATTTTGTTTCACCTGTATGTTTTTTTGGACTCTCGAAGTGCA
Associated Phenotype:
Not determined