Busch Lab

ZMP

si:dkey-220o5.1

Ensembl ID:
ENSDARG00000078815
ZFIN ID:
ZDB-GENE-081105-95
Description:
Novel protein similar to vertebrate G protein-coupled receptor kinase 5 (GRK5) [Source:UniProtKB/TrE
Human Orthologues:
GRK4, GRK6
Human Descriptions:
G protein-coupled receptor kinase 4 [Source:HGNC Symbol;Acc:4543]
G protein-coupled receptor kinase 6 [Source:HGNC Symbol;Acc:4545]
Mouse Orthologues:
Grk4, Grk6
Mouse Descriptions:
G protein-coupled receptor kinase 4 Gene [Source:MGI Symbol;Acc:MGI:95801]
G protein-coupled receptor kinase 6 Gene [Source:MGI Symbol;Acc:MGI:1347078]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa18662 Nonsense Available for shipment Available now
sa12450 Nonsense Available for shipment Available now
sa27261 Essential Splice Site, Missense Mutation detected in F1 DNA Not yet available
sa41284 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa18662
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008283 Nonsense 51 575 3 16
ENSDART00000141513 Nonsense 51 576 3 16
Genomic Location (Zv9):
Chromosome 8 (position 46885614)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 44661469
GRCz11 8 44655375
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ACCAYAGCAGTAYAATTTGAAAAWTTTTCCTTTTGTTTTGTGTGTCAGAA[C/T]GAGACTACGTGTGCCTGWGTGAGAGGCAGCCCATCGGGAGACTTCTGTTC
Long Flanking Sequence:
CAGAATGGTTTACCTCCCATCCCTATGTCTGGATTCTCACAGCTCCCTTTCAAAGTTCCAAGATATGTTATTCCTAGGTAACAACCTTTGAAAATAATAAAACCGGCTCATCTGGGTTCTGCAAATTGTTGTTACTATCATTGAATCATCAAATACTATCAATATTTATGCTATATAATTTGACTTAAAAAAATTAAGAAAATTTAAAAAATTAAAAATTGTATTTAATCTTGTGATGCAGTGCAGATATGTAATTTACCACAGATTTAAAGTGCTGAAAAGTTATTGTTTCTAAATAGCAACTTTAATTTTCAGTGTTTAGAATTACATTTGAAACATCAGTAAATGAAGCATTGTTTTTTTGTTTTTTTTTTTGTTATCTTTTTCCCCCATTAAAGTATGCATATGTTTTTATTAGATGTATATCAAAGTCAATTTTTTCACCATGATACCATAGCAGTACAATTTGAAAAATTTTCCTTTTGTTTTGTGTGTCAGAA[C/T]GAGACTACGTGTGCCTGTGTGAGAGGCAGCCCATCGGGAGACTTCTGTTCCGCCTCTACTGTGAGACCCAACCAGAGCTTCAGCGATGCATACAACTTCTGGATGCCATGGTATGTTAATGTGCACATACACATATCTCTGATGCTTAGTGCACCTGTTTTATTTGCTACTGAAAATGGATTTTGTTGGTCAAAACAGCTTTTAGTTACTATTTGCTGGAACTATAAAAAATAATATCATCAGCTTAAGAAAAAAAAAAGACAGGGAAAGGGTGTACATAGGCTGTGTCCGTAACCGCATACTTCCATACTATATAGCTTGCTAAAAACAGTATGCGAGCCGAGTAGTATGTCCGAATTCATAGAATGTGAGAAGTACCCGGATGACCTACTACTTCCGGCGAGATTCTGAAGTGCGTATCCCATACACGCTGCGCTTTATCCTGATGCCCTGCGAGAGAATTCGAGAATGGGAGTGAAGCAATGTAACTCACGAGGGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12450
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008283 Nonsense 144 575 5 16
ENSDART00000141513 Nonsense 144 576 5 16
Genomic Location (Zv9):
Chromosome 8 (position 46871430)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 44675653
GRCz11 8 44669559
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TGCAAAGAAAATCTAGAACTGAGCCCCTGCAAGGAAATCTTYAGTGACTG[T/A]CGCAAGTAAGTAARATCWGGACTTCTGTTGCACCTATACACTAATGTGTA
Long Flanking Sequence:
GAATTTGTCATTAAACACTTCTCTGTAATAGTGTTGGTATTTCTAACAGTGTCATTAATTTTAATGACATTTAAATATAAAGAGCTCATGATAGTCTTATGAACACCCCTTCAAGTGTTGTGCTGCATGGTTGCTTTTTAAAATGTTGTGCATTGGGGTCATTAGCTGTCATTAATATTCTGCATTTTACTATGGCTTGTTTGTTTATATGTATAATTTGTTTGATTTGGGTCATTTAGGATGATTACGAGGTATCTCCAGATGAGAAGAGAAAGAGTCGAGGAGATGAGATCATCAAGAAATTTCTCAACAAGCAGGTGTGATTTGGTTTAACTGATCTTAAATGTTTTGAATTTTGTATGTCCCCATCAGTCAGTAATTAGAGCACTTCTTTCCTTTTTTTGACAGTCCTCTGAGTGTGTGGATGTTGCTGAAAGTCTTGCTGAAAGATGCAAAGAAAATCTAGAACTGAGCCCCTGCAAGGAAATCTTTAGTGACTG[T/A]CGCAAGTAAGTAAGATCTGGACTTCTGTTGCACCTATACACTAATGTGTAATGTGCAGTTTTATATACTAAGAAAATTCAATTAAATTGTTTTAGATTTAAATATTTTACTGTGCCTTAAAATGACTTTGAAAACATACACTATTGAATATACACTGCTCATATATAATTAATAATACTATAACATTTATAATTATTATATATATATATATATATATATATATATATAATATATAATATTATAATATATGGATGTGACATTTGCAGTAAAAATTCAAAACATTAATTCACAGATAAAGTATGTTAACATTTATATTGAAGCATCTCTTTCTATTTTTTTAAAACAACTAACCACAGAGTTTTTGGATCAAAAAAATTAAATATAAAGGAAAAAAAACATAGGTTGGGGCGTCATGGTGGCGCAGTGGGTAGTACGAATTCCTCACAGCTAGAAGGTCACTGGTTCGAGCCCCGGCTGGGTTAGTTGGCATTTTTGTTTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa27261
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008283 Essential Splice Site 421 575 12 16
ENSDART00000141513 Missense 422 576 12 16
Genomic Location (Zv9):
Chromosome 8 (position 46859790)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 44687292
GRCz11 8 44681198
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAGAGTACAGTGACAAGTTTTCAGAAGACACCAAAGCCATCTGCAGGATG[G/A]TGAGGTCACACACACACACAAAACATGCTGGTCAAGTTTTTTTTTGCACC
Long Flanking Sequence:
CCTTATAAAATGTTTTGTATTTACCTACAAATATATGAAGCAGTTTTAACATTGAAGTAATCAATGTTTTTAAACACCAACCAAGCATGTTAGCTTTTTTTTTAAGGATTATATGTCTCTCAAGACTTTAGTAAAAGTTGTTGAAAATCCAGCTTGGTCATTTAAGGAATAAATTTATTTATTTATATGAACTAAAGTTACTTAATGAAACTCTTTTTGTCTATTCTAGAACGTATGAAACATTAAAATGTTGTTTGTTGATTGATAAACTCAAATTGTATTGATGGACAGCTCCAGAGGTGATCAATAACGAGCGGTATAGCATGAGCCCTGACTGGTGGGGGTTGGGTTGCCTGATCTATGAGATGACTGCTGGTCGATCGCCTTTCCGAGCTCGCAAAGAGCGAGTAAAGAGAGAAGACGTGGAGAAGAGGGTGCAGGAGGAGGAAGAAGAGTACAGTGACAAGTTTTCAGAAGACACCAAAGCCATCTGCAGGATG[G/A]TGAGGTCACACACACACACAAAACATGCTGGTCAAGTTTTTTTTTGCACCATTATCTTGTCAGTCAGACCCGACACAGAAGCTGATTTAGAGTCCACTAAATAAGCCCACAAAACTAGTGAAGGGGAAACATCTGATAATGTTCTCCCTGAAATCATTTTTAAAAATCAAATTGCATTCTGTCATGTTGCTAGTTTAATGCTAATCTAAAATGAAAGAGTGCATCTGTCTCATGGTGCTTTTAAACCATAACATGTATTTTTTGAAAGAGATTTGAAAGTTAGCAAGAAGCCTTAAGATGACAATTGACCCTTCGCTAAGTCCTGCCCTGCTTACTTACTGTTGTTACGTCTGTCAAGCTTTCATGTCTGGCACGTCTATTACAATATGTACGCGCCGGTGTCAGACATTCCCAGGGATATAATTAGTCATTTTTGGTAAACAGGTGAGATGTCTGAGAAAGCCAGACATAAAGGACTACAGTATGCATTACAGGTGTAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41284
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000008283 Nonsense 433 575 13 16
ENSDART00000141513 Nonsense 434 576 13 16
Genomic Location (Zv9):
Chromosome 8 (position 46856870)
Other Location(s):
Assembly Chromosome Position
GRCz10 8 44690212
GRCz11 8 44684118
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CCTCTTATCCCACAGCTGTTATCCAAAGATCCCAAGCAGAGGCTCGGCTG[T/A]CAGACGGACAGAGCTTCTGGAGTCAAAGCCCATCCTTTCTTCAAGAACAT
Long Flanking Sequence:
CTTTGACATGGACTGTAAACCCTGCGGCCTTATATAGACAGGTGTAGGCCTTTTCAAATCATGTCCAATCAACTGACTTTACCACAGGTGAACTATAATTAAGCTACTGAAACAACTCAAGACTGATCAGTGGAAACAGAATGTACCTGAGCTCAATTTAGAGCTTCACAGCAAAGGCTGTGAGTACTTTTGTACATGTGAGTTTTCAGGTTTTTTATTTTTAATAAATTTGCAACAGTTTAAAAAAAAAAAAAAAATCACATTGTCATTATGCGGTATTGTGTGTGGAATTTTGAGGAAATATATCAATTTAATCCATTTTGAAATAAAGCTGTAACAAAACAAATGTGAAAAAAGTGAAGCGCAATGAATACTTTCCGGATGCACTGTATGTTACATGCTGCTTTCAAAGAATATATAAACCCTTTCATAATGTGCTGTTGTGGTTTACCTCTTATCCCACAGCTGTTATCCAAAGATCCCAAGCAGAGGCTCGGCTG[T/A]CAGACGGACAGAGCTTCTGGAGTCAAAGCCCATCCTTTCTTCAAGAACATCAACTTCAAGAGACTAGAGGCTGGCATTTTGGAACCTTCATTTGTGCCTGACGTGAGTTTTATATCAAGATTGACAAACTGTTCTTTGTGAGCTCACAATTGTCTTCTTGATTTAAATAATGAATCCGCACAGGTTAATCTAGAGACATTAAAAACACTTTGTAAGCTTTAATCAAAAACTAAAAATTTGCATGTGGTCTGGATTGGTATTTCTTCTCTAATGACAGCAGTCTGAGGGCTTGGACAGACTGTTAGTTTGTTGTGAGGAGATGGTGAGGAGGATAGCTCAAACAAAACTCCACTTTCTGTTCAGTATTCCGGAAGTAAACAGAAACTTTTGACATTATGACACAATAGCATAATATCTATAAAATAATGATACGGATTCCAATAATAATTAAGGGTGTCACGATCCTCCAAATCCTCGATTCGATTACATTTTCGATTCTA
Associated Phenotype:
Not determined