Busch Lab

ZMP

ADAMTS14

Ensembl ID:
ENSDARG00000078494
Description:
ADAM metallopeptidase with thrombospondin type 1 motif, 14 [Source:HGNC Symbol;Acc:14899]
Human Orthologue:
ADAMTS14
Human Description:
ADAM metallopeptidase with thrombospondin type 1 motif, 14 [Source:HGNC Symbol;Acc:14899]
Mouse Orthologue:
Adamts14
Mouse Description:
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14 Gene

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa22180 Essential Splice Site Available for shipment Available now
sa15424 Essential Splice Site Available for shipment Available now
sa44777 Nonsense Mutation detected in F1 DNA Not yet available
sa35379 Nonsense Mutation detected in F1 DNA Not yet available
sa22179 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa22180
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108989 Essential Splice Site 50 917 1 24
Genomic Location (Zv9):
Chromosome 12 (position 49275137)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 48046337
GRCz11 12 48020298
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCCATTAAAAGGGACAAAGATCGAAGGCCAGACGAGCTCCACAATGAAGG[T/C]ATGCTGAGGAGTAATGACGGAAACCTGCAGAACTATTTTTATTATTATTA
Long Flanking Sequence:
GAGTTTTCCAGTACTGGGTTGCAGCTGGAATGGCATCTGCTGTGTAAAACATGTGATGGATAAGTTGGCGGTTCATTCCGCTGTGTCGACCACAGATTAATAAAGGGACTAAGCCGAAAAGAAAATGAACGAATGAATGAATAAATTCTAAACTATCTGCTCGTGTTTCAGTGTGTGTATATGTGTTTATGTGTGTGTGCATGTACAGTATATGTGTTTGTGTGGGTACATTTGAGCATATGTGTGTGTTTCTATATATATGTATGTGTGTGTGTGTGTGTGTGTGTGTGAGTGTGCACATGTGTATATATATTTATTTGGTGTGTGTGTGTGTGTTTTCAGGCGGGCTTGATTCGCACTGATGATGAGGAGTTCTTCATCGAGCCGCTAGAGAAAGGTCAGCAGGAGGTCGAGGTCAAAGGTCGTGTTCATGTGGTCTACAGGAGGTCGGCCATTAAAAGGGACAAAGATCGAAGGCCAGACGAGCTCCACAATGAAGG[T/C]ATGCTGAGGAGTAATGACGGAAACCTGCAGAACTATTTTTATTATTATTATTATTGTTGTTGTTATTATTTTTATATTACTGTTATTGTTACTATTATTATTACTATTATTATTTTTTTTATATTTTTACTTTTGTTGTTATAATTATTTCTATTATTATTACTATTATTGTTGTTGTTGTTGTTATTATTATTGTTGTTGTTGTTATTTTTAAAATTACTATTGTTACTAATATTTTTACTATTATTATTATTATTGTTGTTAATATTTTTAATATTACTATTATTGTTACTATTATTATTACTATTATTTTATTATTATTATTAGTATTTTTACTTTTGTTGTTATAATTATTTCTATTATTATTATAATTATTATTATCTTTATTATTATTATTATTATTATTATTATTGTTGTTGTTGTTATTATTTTTAATGTTACTATTGTTACTAATATTTTTACTATTATTATTATTATTATTGCTATTATTATATTTACTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15424
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108989 Essential Splice Site 50 917 2 24
Genomic Location (Zv9):
Chromosome 12 (position 49271531)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 48042731
GRCz11 12 48016692
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TRAATTCAGATGTATTTCTCTGCTTTGACACAMTGTGTTTCCTTGTTTCC[A/C]TGTTTAGTGGCAGAGTTYGGTATCGCTGAGCTGCCGAACGYTCTCAGYGT
Long Flanking Sequence:
AAAACATATGAAGGTCATGTGATCATCAGGATCATCACACACACACACACACACACATGCTCGATTCGTGTCATAGCCAGACTCTGCTGTATGAGTGTAATATCAGCAGTAATCCGCCAGTGTAATGATCTTCTGCTGTGACGTGTGTGGAATTATGGGAGAATGTCAATGTAAATCCCACATGTGCGGCTCTTTCAGGAGCGCCAGAGTCTCCACATTCTCCACTCGGTTATTCACCTGCAGTTCCCTGGCTGGGCTGGAAATCACTCTTGTTCTGCAGCTTCTGCTGTGTCAGATTTATGACCTTCAGTTTCACCTTCACACTTTCATCTTTTATTACCAGGCCAGAATCTGTCGACATGTTTTGCCATTCCTGCTCAGAATTTAGTAAAAAAAATATGGGAGTTATACTAAATAAAAACTTGAAATAAAAAAAACAAGGAATTTTTATGAATTCAGATGTATTTCTCTGCTTTGACACACTGTGTTTCCTTGTTTCC[A/C]TGTTTAGTGGCAGAGTTCGGTATCGCTGAGCTGCCGAACGCTCTCAGCGTTTTGGAGGAGAAATTATCGGAGACGGAGCGCAAACGCAGACACGCGAAAAAAGACGACTACAACATCGAAGTGCTACTCGCGGTGGACGACTCGGTGGTTCGCTTTCATGGAAAAGAGCACGTGCAAAACTACGTCCTGACGCTCATGAACATAGTAAGTCAAGCACAGCTTTCACTATTACAGCTTAAAACACAGGAATCATTGCAGAGTTGTGGATACACTTCAAGCATTTTCCAGTAATGTTTATTAAACTGGAATAATAAATAACAAATGTAAAGTTTGCCGCAAATTAAATTTTGATTATGTTACTAAATGTTGTTCATTTTTTTAACAACAGTAGTAACAGAGTTAAAAGTAACAGGGTTGATGGTAACAGAAATTGGCGATAAAAGAGTTGACGGTAACAGAGTTGACGATAACAGTTGACGATAACAGAGTTGACGATAACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44777
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108989 Nonsense 196 917 5 24
Genomic Location (Zv9):
Chromosome 12 (position 49261671)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 48032871
GRCz11 12 48006832
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACGATCACGCCGTTTTCCTCACCAGGCAAGACTTTGGTCCTGCAGGTATG[C/T]AAGGTACAGTGTTTCTGTCGATCGCCGCTGTGCAGAGTAAGTGCTTCTAC
Long Flanking Sequence:
ATAATATATACAATAAAATATATTATAAAAAAATAATTATAAAGTGATTTAAAAATAAATAAATAAAAATAATATTAAAAACACAAATAAAAAAAATAAAAAATCATAGAATAATAATAATAATGAAAAACACTATATATATATATATATATATATATATATATAATGTTTTATCTTTTTTTGTTATTATTCATCTTATTAAACATTTTAATTACTTAATTAATTAATTCTACAAATACAAAGCACAAAATCAAATGATAAAATGCATAGTACAGAAAGTATTACTCTGTGTGTATTTAATCCATCAGATATGTGTCAGTATTTTATTGTGTGTGTGTCTGTGTTTAGTCCATCAGTCTGATCGAGCGTGGGAACCCGTCCCGCAGTCTGGAGCAGGTGTGCCGCTGGGCGAACTCTCAGAGAAGCAGGACCCGCAGCACGCCGAGCACCACGATCACGCCGTTTTCCTCACCAGGCAAGACTTTGGTCCTGCAGGTATG[C/T]AAGGTACAGTGTTTCTGTCGATCGCCGCTGTGCAGAGTAAGTGCTTCTACACACACCTGACCGTCCCTTTGGCATGGAGAAGAAAAACTGGATATGCACTATCAATATTTCACTAATATAGAGATAATCTGAGCGTCTGCAGGATATTAACACACTCCGTTTGACACGTTGATGAAAAACTGGATATTCACTATCAATAATAGACTAATATAGAGATAATTTGAGCGTCTGCGGGATATAACACACTCCATTAGACATGTGGACAAATAAATGACAATTCACTATCAATAATACACTAATATAGAGATAATCTGAGCATCTGCGGGATATTAACACACTCCGTTAGACATGTAGACAGAATAACGACAATTCACTATTAATAATACACTAATATAGAGATAATCTGAGCGTCTACAGGATATTAACACACTCCGTTTGACATGCAGACAACAAAATGACAATGCATTACCAATAATACACTAATATATAGAGATAATCTG
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa28027
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
T > G
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108989 Nonsense 282 917 8 24
Genomic Location (Zv9):
Chromosome 12 (position 49247693)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 48018893
GRCz11 12 47992854
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTGTGGCTGAGAGAGCTGCAACTTAAGTCCACATTTTTTTCAGCTCGTA[T/G]GACTGTCTTCTGGATGACCCATTCGAGCTGAAATGGCCCAAACTCACCGA
Long Flanking Sequence:
TAGGATGTGGAAAGAGCATGAGGTTAGGGCTGCTCGATTGCGCCCCCTGTTGAACAGAATACTGCCATCATTAAAACTGCCTTAAAAAGTTGGAAAAAGGCATCTGCATGTAAAAATCTGTAAGGGCTGAACTCATTAATGCCGAACACTGTAGATGTTATGTGTTATTGTACAGAGCTGTGATTGTATTGTGTTGCTGTTTCAGGCTGGGAATGGAGCATGATGGGCAGGGGAACCGCTGTTCAGATGAGACCAGTATGGGCAGCATTATGGCTCCCCTGGTCCAGGCTGCGTTTCACCGATATCACTGGTCCCGTTGCAGCAAGCAGGAGCTCAACCGATATATACAGTACGACACCTGCCTTTATTATAGCATGCATATTCATAATTAGCGACAACATCACTTATATTACACTCACCGCCATGTTTGTGTCTGAAATAATCACAACTATTGTGGCTGAGAGAGCTGCAACTTAAGTCCACATTTTTTTCAGCTCGTA[T/G]GACTGTCTTCTGGATGACCCATTCGAGCTGAAATGGCCCAAACTCACCGAACTCCCTGGCATTAATTACTCCATGGACGAGCAGTGCCGCTTTGACTTCGGTGTGGGATATAAGATGTGCACGGCTGTAAGTGCTCTAATTAGTTAATCTTCTGACTGTAAACTCCGGATCAAAGCCTTTATAATGAGACTCGTTTATTGTGCAGCTGAAATGCCATCATATGCATGAGTCATGAGCAGAATATACAGACTTTTTTTGTTTGTTTGTTATTTCTGCACAGATTTTGTACAAATATATATTTTAATTTATGCAGAAGGATTTTAAATGTGGTAACTAAAACACTGATTTGATTTGTGTCATGTCATTTGAGTATCTCTTTGCATAATAATAAAATTAAAAACTTGACACATGAAATAAAAACTTGTAACAATTTAATTTATGCAAATCCAATTAGAACCACTTGTTTGTAAACAAAGCAAGTCTCTGATATAATATATCCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa35379
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108989 Nonsense 443 917 11 24
Genomic Location (Zv9):
Chromosome 12 (position 49243598)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 48014798
GRCz11 12 47988759
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTATCAGCTGTGTAACACTGAGGAGTGTCCCGGCCCGTATGAGGACTTC[C/T]GAGCGCAGCAGTGTGTTCAGCGCAGCAACAAATACCACAACAACATCAAA
Long Flanking Sequence:
CGTGTTCATGTGTGAGTGTGCATTCATGTGTGTAATGTGTATGTGTGTTGACTCATGCGTGTCTGTGTGTGTGTGTGTTGCAGTGGTGTTTTAAGGGTCACTGTATCTGGCGCTCGTCTCATCAGCTCTATGGTCACGACGGCGGCTGGAGCTCGTGGGGGAAACTCAGCTCGTGCTCACGCTCGTGTGGAGGCGGCGTTCGCTCACGCACCAGACACTGCAACAACCCTGTGTGAGACTCTCACACTCACACACACACACACACACACACCTGCTGCTTTATTAATTATATTACACCTTTGCCCACTTAGAAAAGCACGTCACAGTGGCTTGAGTTCAGATTCAGATGCAAATTAATGTTTTATTGTGTGTCTGTGTCTGTGTGTGTCTGTGTGTTCACTGTCTGCAGTCCAGCATATGGTGGTCGTGAGTGTCCCGGCTCAGCGTTTGATTATCAGCTGTGTAACACTGAGGAGTGTCCCGGCCCGTATGAGGACTTC[C/T]GAGCGCAGCAGTGTGTTCAGCGCAGCAACAAATACCACAACAACATCAAACACACATGGCTGCCCTACGAACACCCCGACGGTGAGGCGTCCTCTGTCATCATGAAATTTATAACAGTGATAATGAACATAACGCGGTTCATCAGTAACTCTCCTCATATGCCGACAGAAGGCCGGTGTGCTGCATGTAAACGCTAATAAAAGTCTGCCACTGTATGAAGCTTGGCCTTGGTAGTTTTAGAAGATCAGTTTTCACCAGGGGCATTTCTAGACATAAAGCTGTGGGCACAACTCGCCCTCCTAAATAAATAAATATATATATATATATATATATATATATATACAGTTAAAGTCAGAATTATTCGCCCCCCTTTTAATTTTCTTTTTAAATATTTCCCAAATGATGTTAAACAGAGCAAGGAAATTTTTACAGTATTTCCTATAATATTTTTTCTTCTGGAGAAAGTCTTATTTGCTTTATTTCGGCTAGAATAAAAGCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22179
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108989 Essential Splice Site 794 917 21 24
Genomic Location (Zv9):
Chromosome 12 (position 49225022)
Other Location(s):
Assembly Chromosome Position
GRCz10 12 47996222
GRCz11 12 47970183
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGTCACATAAAATTAACATTGCTTTTTTGTGTGTGTGTGTTGTGTGTGTA[T/A]GCAGTGTTCAGTCAGCTGTGGTGAAGGGATCCGGCAGCGGCAGGTGATCT
Long Flanking Sequence:
ATGTGTGGCTAAGAAATAATTATGTCTTTTGGGTGTGGTCAGAGATATCCTTCATTTTGAGCCCTAAAAAAAAGTCATGTGAAATAAAAACCAATTGCGATGCGACACAACCCATTTGCTCATGCACAGTGAGCAAGCTCACACATAACACACAAACAGTGAAATAAACGAGGAGGCATGTGGACAACTCAACATCTAAATCAAGTCATTTTAGCATGCTAGAGTCACATTTATTAATACAAAATGTATATTTTAAGCAACAAAATTGTGGCTGGTGAAAATGGAAAGTGGCTAGTAATGTTGGAAATCTACTAGCCACAGTGGCTGGTGATCAAAAAAGTTACTGTCAAGCCCTGAACACACTTAAATACTCTTTTAAACATCATGCAAAAGTAATGTAACAAATTGCTTAAAAATAACATATTAATGCGTTTAGTTTCATTTTAAAGTAGTCACATAAAATTAACATTGCTTTTTTGTGTGTGTGTGTTGTGTGTGTA[T/A]GCAGTGTTCAGTCAGCTGTGGTGAAGGGATCCGGCAGCGGCAGGTGATCTGCAGACCCGCTGACAGCAGTTCAGCTCCATGTGACGCAAATAAGCCTGAAAATGTGTCCATCTGCAGACTTCAACCCTGCGCAGGTAAACACACATTAACAATATTTTTTAATCTGTAATTTAGGTAATCAGTTCTCATTTTAGAATCTTTTTATTTGTATATTGGTTATTTTAGCAGAAGCATTTATATTATCTGTGCCCAAAATACTGCACGGTGACGTTCTGTCTGCCAGGAAGTGGGCTTTTGTGTGATTTACCTATTCATTTTTTTCTCTCGCAGGAGCGCCGACTCTGCCGAGCCCCACTAATGTTTCTCTGGATAATTCCACCACTGAGGAAGAGAAACTTCCAGAAAACACCCTGGATAAAATGTCCAGTAAGTGACAGTGAAGCAGCTCAGTGTTTATTGATTTATTTTTATTTCTGCACACATCATATACAGAGACGACA
Associated Phenotype:
Not determined