Busch Lab

ZMP

si:dkey-175m17.7

Ensembl ID:
ENSDARG00000078317
ZFIN ID:
ZDB-GENE-091204-18
Human Orthologue:
DUSP10
Human Description:
dual specificity phosphatase 10 [Source:HGNC Symbol;Acc:3065]
Mouse Orthologue:
Dusp10
Mouse Description:
dual specificity phosphatase 10 Gene [Source:MGI Symbol;Acc:MGI:1927070]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa43659 Nonsense Mutation detected in F1 DNA Not yet available
sa23954 Nonsense Available for shipment Available now
sa7482 Missense Mutation detected in F1 DNA Not yet available
sa1705 Nonsense F2 line generated Not yet available

Mutation Details

Allele Name:
sa43659
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109626 Nonsense 215 904 1 3
ENSDART00000139058 Nonsense 215 892 1 3
Genomic Location (Zv9):
Chromosome 21 (position 26678090)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 27247001
GRCz11 21 27283696
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTACAGTATCTCCTGGAGGAATATTGGAGTTTGTACCAGCTCAAAGACAG[C/T]AGTCAAAATCCAAACCAACAAGAGAGAGAGACTTGTCATCAAAGACTTGC
Long Flanking Sequence:
CACAACCCCAACCCCCACCACCCCGTTCCTATCCAGGTTCCAACTACCTGTCTCTGGAATGCAAGCGCAGGCAGCCGTCCCATGTTCAGAGAGATAAAGGGGAACGAGGTGCTCTCTTCGAGGAGAGTGACCACAATGCTAGTCATTGTCACAGCAATGGGACTGTGACTTTAGGTCCCAGACCTCACAAGCACACACATACCATTGACATTAAAGTGTCTTTGGACAAAGGTGGAAGAGGGGGATCTTACATAGAAAAAGGTCGCAGCAGCAGTCTTACCCGAAGTGAAAGCATCAAGGGGAGCAGAACTAAAAGGGTGTCCCTGCACTTGGACTCTGGGCAAGGTGAAAGAAAATGCAAAGGAAAGTCTTCCGAGTTAGTGGAGAAGCATCAGAACTATCATCAAAGTCAAAACAGGACTCCGCACAGTAGCCATCTTACAAACCAACTTACAGTATCTCCTGGAGGAATATTGGAGTTTGTACCAGCTCAAAGACAG[C/T]AGTCAAAATCCAAACCAACAAGAGAGAGAGACTTGTCATCAAAGACTTGCTCTGCAACTGCCAGTTACCCATTGCACAGTGAGAGGGACGCATCATCTGTTGGAAACAAAGAAAACTCCAAACTGGGACCCGGCCACCAGCTGCCCCACGCCCACAGCCTATCCCGTCACCACAGTTCAGCCCCGTTACCTCATGCTGCCATCCTAAACCCTCAGTACCCTGCTGTCCCACCCCCACTCCCTTCCAGAGCCCCTTCCTCCTACCAGCACATCAGTCAGCCCCGTTCGTCACGAATTAGAGAACATCGGCCACAAATTCTTCACGCCTTGCCTCTCTCACCTACATCTTCCCGGGGAGGCTTCCCCAGTCCTGACCATACATGTACGATTGACTTTTCCCACCCCTGTGGCTGTTGGAGGTTGGTGCGTTGTAGAAGAGGTAGAGGTCACACGGCTGGCTGCCACAGTCATAATACAAGCCCATCCTCTTCATTTTCCCAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa23954
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109626 Nonsense 319 904 1 3
ENSDART00000139058 Nonsense 319 892 1 3
Genomic Location (Zv9):
Chromosome 21 (position 26678402)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 27247313
GRCz11 21 27284008
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCAGCACATCAGTCAGCCCCGTTCGTCACGAATTAGAGAACATCGGCCA[C/T]AAATTCTTCACGCCTTGCCTCTCTCACCTACATCTTCCCGGGGAGGCTTC
Long Flanking Sequence:
AAAGGGTGTCCCTGCACTTGGACTCTGGGCAAGGTGAAAGAAAATGCAAAGGAAAGTCTTCCGAGTTAGTGGAGAAGCATCAGAACTATCATCAAAGTCAAAACAGGACTCCGCACAGTAGCCATCTTACAAACCAACTTACAGTATCTCCTGGAGGAATATTGGAGTTTGTACCAGCTCAAAGACAGCAGTCAAAATCCAAACCAACAAGAGAGAGAGACTTGTCATCAAAGACTTGCTCTGCAACTGCCAGTTACCCATTGCACAGTGAGAGGGACGCATCATCTGTTGGAAACAAAGAAAACTCCAAACTGGGACCCGGCCACCAGCTGCCCCACGCCCACAGCCTATCCCGTCACCACAGTTCAGCCCCGTTACCTCATGCTGCCATCCTAAACCCTCAGTACCCTGCTGTCCCACCCCCACTCCCTTCCAGAGCCCCTTCCTCCTACCAGCACATCAGTCAGCCCCGTTCGTCACGAATTAGAGAACATCGGCCA[C/T]AAATTCTTCACGCCTTGCCTCTCTCACCTACATCTTCCCGGGGAGGCTTCCCCAGTCCTGACCATACATGTACGATTGACTTTTCCCACCCCTGTGGCTGTTGGAGGTTGGTGCGTTGTAGAAGAGGTAGAGGTCACACGGCTGGCTGCCACAGTCATAATACAAGCCCATCCTCTTCATTTTCCCACGCCCAAGGAACAAGTGCTACCAACGGAGGTGGCGGAACCATGGGCCTGAAGACTTTAGGAGGGTGTCTATCTACTGCTTCCACCACCAACACCTCCTCTTCCAATAGCACTGTCTCAGATTGTCGTACAGGACTGCTTAGACCATTAGGTTGTGCATCCTGTTCTGGGGAGGCTGGAGGTTTTGAGAGTCCTGCTGCTTTCCGTAAGAAACTTGTTGGGGGTTGTTTACCCTGTGCCCCCTTGTCCTCATCTGCACCTCTTCGAGCACTCCAGAGTTGCGTCAGTGGGTGCAATCCCAAAGCAAGTCAAACT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa7482
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > A
Consequence:
Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109626 Missense 417 904 1 3
ENSDART00000139058 Missense 417 892 1 3
Genomic Location (Zv9):
Chromosome 21 (position 26678698)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 27247609
GRCz11 21 27284304
KASP Assay ID:
554-4093.1 (used for ordering genotyping assays)
KASP Sequence:
GGAGGGTGTCTATCTACTGCTTCCACCACCAACACCTCCTCTTCCAATAG[C/A]ACTGTCTCAGATTGTCGTACAGGACTGCTTAGACCATTAGGTTGTGCATC
Long Flanking Sequence:
AAAGAAAACTCCAAACTGGGACCCGGCCACCAGCTGCCCCACGCCCACAGCCTATCCCGTCACCACAGTTCAGCCCCGTTACCTCATGCTGCCATCCTAAACCCTCAGTACCCTGCTGTCCCACCCCCACTCCCTTCCAGAGCCCCTTCCTCCTACCAGCACATCAGTCAGCCCCGTTCGTCACGAATTAGAGAACATCGGCCACAAATTCTTCACGCCTTGCCTCTCTCACCTACATCTTCCCGGGGAGGCTTCCCCAGTCCTGACCATACATGTACGATTGACTTTTCCCACCCCTGTGGCTGTTGGAGGTTGGTGCGTTGTAGAAGAGGTAGAGGTCACACGGCTGGCTGCCACAGTCATAATACAAGCCCATCCTCTTCATTTTCCCACGCCCAAGGAACAAGTGCTACCAACGGAGGTGGCGGAACCATGGGCCTGAAGACTTTAGGAGGGTGTCTATCTACTGCTTCCACCACCAACACCTCCTCTTCCAATAG[C/A]ACTGTCTCAGATTGTCGTACAGGACTGCTTAGACCATTAGGTTGTGCATCCTGTTCTGGGGAGGCTGGAGGTTTTGAGAGTCCTGCTGCTTTCCGTAAGAAACTTGTTGGGGGTTGTTTACCCTGTGCCCCCTTGTCCTCATCTGCACCTCTTCGAGCACTCCAGAGTTGCGTCAGTGGGTGCAATCCCAAAGCAAGTCAAACTGGCAGCTCCACATGTAGCTACTGCAGTAGTGACCCCATTGTAGTTACCTTTAACCCACACAGAGGGAATCCTCCTAACATGGGCCATAATGTTGGCGCACATACCATGGGCGGATACCAGCCCGATGATGACGATTACAGTGTACGCACAATTTGGCCAGAGGAACTAGCAAAGAAGATGACTCGTTCGAAAACCCAACCTATCCACCACAATTCAGGCTCAGGGAGGACCTGCATGGGCCACAACCAGAATAGTGGCAATGGTGGCAATCCTGTAATCCTTGACTGTCGGAATCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1705
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000109626 Nonsense 808 904 2 3
ENSDART00000139058 Nonsense 796 892 2 3
Genomic Location (Zv9):
Chromosome 21 (position 26680469)
Other Location(s):
Assembly Chromosome Position
GRCz10 21 27249380
GRCz11 21 27286075
KASP Assay ID:
554-1651.1 (used for ordering genotyping assays)
KASP Sequence:
TACAAAAGRCTCCCCGCTACTGACAACAGCAAGCAGAACCTGCGACAGTA[T/A]TTCGAAGAGGTTTTTGAGTTTATAGGTAAGAGAACGTGTCAACTTTTGTA
Long Flanking Sequence:
AGAGTGAAGAGTCTTCAAACAGGAAAGTTAAGGAGGAGGGATTAAAATTAGTAGAACTATTCGATTTCCTTACATAAGGGCTCTATGACATTATGTTTCAGCAGCATTTTAACCTGTGCCATTTCTAAACGATTGAAAAGAGTCTAAAAAACTTTACATTCTTATCTCATTATACAAACTAATTTAAGCAACATTTTATTTTATTGTTTGTTTTTTCCAGTGCACCTTTCGCTCCCTCTTTCCTCCTCACTCCCAGCATCACTGTCTGACGAGAGTGTGATGACTCCTGATGTGGAGAATGCTGTGATTAGTCCCATCCTCCCTTTCCTTTTCCTGGGCAACGAGCGAGATGCACAGGATCTAGATCTACTTCTTCATCTTAATATTGGTTTTGTGGTCAATGTCACCACCCATCTTCCCCTCTACCATCTGGACACAGGCTTGGTGCGTTACAAAAGGCTCCCCGCTACTGACAACAGCAAGCAGAACCTGCGACAGTA[T/A]TTCGAAGAGGTTTTTGAGTTTATAGGTAAGAGAACGTGTCAACTTTTGTATTTGACATATTCCCAGACTCCATGAAAATGTCTTGGTATGGATAAAGTGTATCAAAAGGCTTGTCTTTTTCTTTTTTAAACTGTTAATAGCCTTTGGCAGTGAACAATTATTTTTAGTTCAGGGGTGTCCAATGCTGCTCCTGATGGGGCAGAATTTTAAAAAATTTAAGCTCCAACACATGTACCTGGAAGATTTTAGTAAGTCTGAAGGCCATGATTAGCAGATTTAGGCTTGCTAGTGTTGGTTGTAAACTCCTCTCTTCTGGACATCCACCCTCGAGGATGAGTTTTGGACATGTTTAAGCTAGTCCGGTACAGGTGGTACTATGGAAGTGGGGCATTTTATTTGGAATAGAGAACCAAGACTTGGCAAGATGTGTCATCCACAATGTCGGTTTGTGTTCTTGAAAATAATGTTATCAGAACGTCTTTATAGCTAATTTGAATTCA
Associated Phenotype:
Not determined