ZMP
si:ch211-204d2.4
Ensembl ID:
ZFIN ID:
Description:
pleckstrin homology domain-containing family A member 2 [Source:RefSeq peptide;Acc:NP_001121835]
Human Orthologue:
PLEKHA2
Human Description:
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 [Source
Mouse Orthologue:
Plekha2
Mouse Description:
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2 Gene [S
Alleles
There are 3 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa34317 | Nonsense | Available for shipment | Available now |
| sa21208 | Essential Splice Site | Available for shipment | Available now |
| sa34318 | Nonsense | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa34317
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000113407 | Nonsense | 60 | 391 | 2 | 11 |
| ENSDART00000133532 | Nonsense | 60 | 391 | 3 | 12 |
Genomic Location (Zv9):
Chromosome 8 (position 11539439)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 11129685 |
| GRCz11 | 8 | 11167390 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCCTTAAAAAACAGAACCTACCTGTTGGAACGGAGCATGTTGGAAGTTTA[C/T]GACTCAGTTACATTTCAAAGGTTTGGTGCTGGCGTGTAACAATGACTATA
Long Flanking Sequence:
CACATTGCTGATCCCTGCGGTGTGAGTATTGCGAACTGAACTCTCATATTGCGATATCGATGCTGAATTGATATATTGTGTGAAGCCCTACTATTTCTGTATATTTTTTCAACAAAGCAAAAGAAAGTTTTATTTAAAGAACTAATGAAAGACAAACACTTGTGCTTGACATTCAGTGTTTTGCAGATCTGGGACAGGACATGCCTTACCTGGACAGACAAAATCGGACCTGTGGATTTCTGGATATTGAGGAAAATGAGAACAGCGACAGGTTTTCCCGCCGTTATTTTATCTTGGACACCGATAAGAATTATCTCCTCTGGTACATGGACAATCCTCAGGTTTGTGTCCAAATGCAGTAGAGAGTTACAAAGGATTTTCTTGTTTACCTTCACTCTAAACCTCAAATTTGCATCCTAAAAATATTTGCATACCTTTTTTTGGCCTATTTCCTTAAAAAACAGAACCTACCTGTTGGAACGGAGCATGTTGGAAGTTTA[C/T]GACTCAGTTACATTTCAAAGGTTTGGTGCTGGCGTGTAACAATGACTATATACTGCATTTTTATTACTTATTTTTGCTGATTCAAATTTCCACTTGGCTGAAGGTTAATGAAGCATCACTGAAGCAGAAACCAAAGGCTGAGTTCTGCTTTGGTAAGTGATTAAATTTGGGTACCTTTTTTGTTTTCTTGTTTTTTACAGTATCATTAACCAGCCGTATTTTTCTTTCAGTAATACATGCGTTATCCAGGCGGTACTTTCTGCAGGCGAACGATGCTTTGGACTTGAAGGAGTGGGTCATTGCTGTAAACAATGCCACAAAAATTACGGTATGTTAAGCTTTTTGTGTATTCATTGATGTCATTTTTGGGATCATTCTTCATCATGTCTACTTATAAAAGTGATAAACCTGGACATTCTCCTCAAAAAAACTATCTTCCTTAGTTTGACCTGAAATGTCTGATAAAAATGCAGGCCCGTAGCCAGCCGATTGAAAGGGGT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa21208
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000113407 | Essential Splice Site | 66 | 391 | 2 | 11 |
| ENSDART00000133532 | Essential Splice Site | 66 | 391 | 3 | 12 |
Genomic Location (Zv9):
Chromosome 8 (position 11539460)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 11129664 |
| GRCz11 | 8 | 11167369 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGTTGGAACGGAGCATGTTGGAAGTTTACGACTCAGTTACATTTCAAAG[G/A]TTTGGTGCTGGCGTGTAACAATGACTATATACTGCATTTTTATTACTTAT
Long Flanking Sequence:
GTGAGTATTGCGAACTGAACTCTCATATTGCGATATCGATGCTGAATTGATATATTGTGTGAAGCCCTACTATTTCTGTATATTTTTTCAACAAAGCAAAAGAAAGTTTTATTTAAAGAACTAATGAAAGACAAACACTTGTGCTTGACATTCAGTGTTTTGCAGATCTGGGACAGGACATGCCTTACCTGGACAGACAAAATCGGACCTGTGGATTTCTGGATATTGAGGAAAATGAGAACAGCGACAGGTTTTCCCGCCGTTATTTTATCTTGGACACCGATAAGAATTATCTCCTCTGGTACATGGACAATCCTCAGGTTTGTGTCCAAATGCAGTAGAGAGTTACAAAGGATTTTCTTGTTTACCTTCACTCTAAACCTCAAATTTGCATCCTAAAAATATTTGCATACCTTTTTTTGGCCTATTTCCTTAAAAAACAGAACCTACCTGTTGGAACGGAGCATGTTGGAAGTTTACGACTCAGTTACATTTCAAAG[G/A]TTTGGTGCTGGCGTGTAACAATGACTATATACTGCATTTTTATTACTTATTTTTGCTGATTCAAATTTCCACTTGGCTGAAGGTTAATGAAGCATCACTGAAGCAGAAACCAAAGGCTGAGTTCTGCTTTGGTAAGTGATTAAATTTGGGTACCTTTTTTGTTTTCTTGTTTTTTACAGTATCATTAACCAGCCGTATTTTTCTTTCAGTAATACATGCGTTATCCAGGCGGTACTTTCTGCAGGCGAACGATGCTTTGGACTTGAAGGAGTGGGTCATTGCTGTAAACAATGCCACAAAAATTACGGTATGTTAAGCTTTTTGTGTATTCATTGATGTCATTTTTGGGATCATTCTTCATCATGTCTACTTATAAAAGTGATAAACCTGGACATTCTCCTCAAAAAAACTATCTTCCTTAGTTTGACCTGAAATGTCTGATAAAAATGCAGGCCCGTAGCCAGCCGATTGAAAGGGGTGGTTCTTTTTTTCTCAAAAAG
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa34318
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000113407 | Nonsense | 212 | 391 | 7 | 11 |
| ENSDART00000133532 | Nonsense | 212 | 391 | 8 | 12 |
Genomic Location (Zv9):
Chromosome 8 (position 11548122)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 8 | 11121002 |
| GRCz11 | 8 | 11158707 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTTCTTTCAGAGGAAAAGCTGGAAGAGGAGATTTTTTATTTTGGATGAC[C/T]AAACTGTGAGCTACTACAAATCTGAAATGGTGAGATGCTGGAAAGGTGAA
Long Flanking Sequence:
TTATCAACAATACATTCTTACAACATGTTAGCCTGTTATTCCAGAAATACTGGATAAAATATATTGCACTGCCTTTATTGCTTAAATTACACACAAGAAAGCAGCTTTTTATTCCCATAATCAGATATATTTATATTCCAACATAAATAAACTTTGTATTTCTTATGAAATTCTTTATTTAATGTTTTGTGAGACTTAATTGCACTTAAGCATTAGGGGATATTTTAAGTTATGTTTGCATTTGACCTGTTCCAAAAATCCACATTCACAAGTTTGAAAGGATTTTGATGTTATACATTAAAAATACATGTATTGTCTGTTTCATTTTTATGCATGAAAGCCATATCATAATATGCTTAGCATGCAGATAGAAACATATAATTTCAAGGTGGCAAAAATTGCATAATCCACAATTGAATCCCCATTGCTCATTTAAACGTACTAATAACATTTTCTTTCAGAGGAAAAGCTGGAAGAGGAGATTTTTTATTTTGGATGAC[C/T]AAACTGTGAGCTACTACAAATCTGAAATGGTGAGATGCTGGAAAGGTGAATTCTTGAACTACATGAATGTGGGTTATATTGATATCATGAAGAGATTTGCAAACCTGTGTTGTTTTAGGACAAGGAACCGTTGCGCAGTATTCGATTGCGGGATGTGCTGAAAGTGAATGAATGTCTTGTGAAATCAGGGTAAGAACATTGCTTTGGTTTTTCTCTCTTTTAAATGTTTTAAATACAAACCTCAAAAAACTGAACTCATCCTATCATTATAAGGAGTAAATCTGTTAAAAACTACTTTACGTCTAGATACTTTGCGATTATTTACCTCTAGTTGAATTGCCATTTTATACTCCTATTTAAGCCGGCACTTCTCTTGGAATTCTGAAATTAAAAATGGAACAATCCACAATAAAGCTTAATTTTTATATTAAGAACAGCAAGTAAATAACTGTAATTGTAATTAAAAAAAAATTAAAAACAATGTGCTTTAATGTTTTTCT
Associated Phenotype:
Not determined