Busch Lab

ZMP

il10

Ensembl ID:
ENSDARG00000078147
ZFIN ID:
ZDB-GENE-051111-1
Description:
interleukin-10 [Source:RefSeq peptide;Acc:NP_001018621]
Human Orthologue:
IL10
Human Description:
interleukin 10 [Source:HGNC Symbol;Acc:5962]
Mouse Orthologue:
Il10
Mouse Description:
interleukin 10 Gene [Source:MGI Symbol;Acc:MGI:96537]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa21894 Nonsense Available for shipment Available now
sa1423 Nonsense Available for shipment Available now
e46 Nonsense Confirmed mutation in F2 line Not yet available
sa44739 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa21894
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110673 Nonsense 21 180 1 5
Genomic Location (Zv9):
Chromosome 11 (position 21971299)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 20977530
GRCz11 11 21138098
KASP Assay ID:
2260-4210.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTGGAGTCATCCTTTCTGCTCTGCTCACGCTTCTTCTTTGCGACTGTGCT[C/T]AGAGCAGGAGAGTCGAATGCAAAACTGACTGTTGCTCATTTGTGGAGGGC
Long Flanking Sequence:
GATAATAAGACAGTATGTTAGAACAACAGATAAATAGACAAATAGAAGGAAAGGAGAATTAATGGACTTAAAATTAGAATAGCCGAGAAACGCAGACATTGGGAATTTGTGGAAATAGCAATTACGAAACTTGTAATAATACAAGATGTTTCTAGAAAATAAACATTTTACATTTAACAACATACATTTAATTCATTTGTCATTAAATCATCCATCCAAGAAAATACATCAGTTGTCAAAAAAAAAAAAAAAAATTATTTATGATGACACAGAATAAGAGAGATGACTGCCAGTAAATGACTACCAACCCCTCCTCCGACAGCACAGGAAATTTAGCAAAATGGGGTATAAAATAAGGCACCCCAAGGAGCTCATCTGTACATCTTCTCACTTGTTGGCTGAAAATCAAGAAAGGATTAAGAAAAAAAAAGAAATTAAATATGATTTTCTCTGGAGTCATCCTTTCTGCTCTGCTCACGCTTCTTCTTTGCGACTGTGCT[C/T]AGAGCAGGAGAGTCGAATGCAAAACTGACTGTTGCTCATTTGTGGAGGGCTTTCCTTTAAGACTGAGGGAGCTCCGTTCTGCATACAAAGAAATTCAGAAGTTTTATGTAAGTACACTTCGACTGATCTCCAGCTGAATGAAATGCCAGTTTTGCAACTCCCATTTCTGCTTTTTGTGTGTTTATGTGAGTGTGTTGTATTGAAATCTGAGGTTCTTTCTAATAGATTTTTTTGTTGTTTACATTGCATCAGGAGTCCAACGATGACTTGGAACCATTATTAAATGAGGACATAAAACATAACATAAACGTAAGTGCCACTGATTTACTCCTACAGCACAACACCAGCAGTTATTCGCACTCAAAATTAGCAATAGCAGAACTAATCATAGTGAAACTGGGTAGGTTTTAAGCGAGTCTAAAATCTTGCGTAGCATCTTGCATCTGCACATTGCTACGGCAGTGTCGAAGTGTGACAACTGTGGGTGTCTGAAACAGCAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa1423
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110673 Nonsense 26 180 1 5
Genomic Location (Zv9):
Chromosome 11 (position 21971314)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 20977545
GRCz11 11 21138113
KASP Assay ID:
554-1344.1 (used for ordering genotyping assays)
KASP Sequence:
CTGCTCTGCTCACGCTTCTTCTTTGCGACTGTGCTCAGAGCAGGAGAGTC[G/T]AATGCAAAACTGACTGTTGCTCATTTGTGGAGGGCTTTCCTTTAAGACTG
Long Flanking Sequence:
TGTTAGAACAACAGATAAATAGACAAATAGAAGGAAAGGAGAATTAATGGACTTAAAATTAGAATAGCCGAGAAACGCAGACATTGGGAATTTGTGGAAATAGCAATTACGAAACTTGTAATAATACAAGATGTTTCTAGAAAATAAACATTTTACATTTAACAACATACATTTAATTCATTTGTCATTAAATCATCCATCCAAGAAAATACATCAGTTGTCAAAAAAAAAAAAAAAAATTATTTATGATGACACAGAATAAGAGAGATGACTGCCAGTAAATGACTACCAACCCCTCCTCCGACAGCACAGGAAATTTAGCAAAATGGGGTATAAAATAAGGCACCCCAAGGAGCTCATCTGTACATCTTCTCACTTGTTGGCTGAAAATCAAGAAAGGATTAAGAAAAAAAAAGAAATTAAATATGATTTTCTCTGGAGTCATCCTTTCTGCTCTGCTCACGCTTCTTCTTTGCGACTGTGCTCAGAGCAGGAGAGTC[G/T]AATGCAAAACTGACTGTTGCTCATTTGTGGAGGGCTTTCCTTTAAGACTGAGGGAGCTCCGTTCTGCATACAAAGAAATTCAGAAGTTTTATGTAAGTACACTTCGACTGATCTCCAGCTGAATGAAATGCCAGTTTTGCAACTCCCATTTCTGCTTTTTGTGTGTTTATGTGAGTGTGTTGTATTGAAATCTGAGGTTCTTTCTAATAGATTTTTTTGTTGTTTACATTGCATCAGGAGTCCAACGATGACTTGGAACCATTATTAAATGAGGACATAAAACATAACATAAACGTAAGTGCCACTGATTTACTCCTACAGCACAACACCAGCAGTTATTCGCACTCAAAATTAGCAATAGCAGAACTAATCATAGTGAAACTGGGTAGGTTTTAAGCGAGTCTAAAATCTTGCGTAGCATCTTGCATCTGCACATTGCTACGGCAGTGTCGAAGTGTGACAACTGTGGGTGTCTGAAACAGCAGATAAAAAGGTAAATC
Associated Phenotype:
Normal
Stage Entity Quality Tag
Larval:Day 5
ZFS:0000037
whole organism
ZFA:0001094
quality
PATO:0000001
normal
PATO:0000461

Mutation Details

Allele Name:
e46
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110673 Nonsense 28 180 1 5
Genomic Location (Zv9):
Chromosome 11 (position 21971320)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 20977551
GRCz11 11 21138119
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATGATTTTCTCTGGAGTCATCCTTTCTGCTCTGCTCACGCTTCTTCTTTGCGACTGTGCTCAGAGCAGGAGAGTCGAATGC[A/T]AAACTGACTGTTGCTCATTTGTGGAGGGCTTTCCTTTAAGACTGAGGGAGCTCCGTTCTGCATACAAAGAAATTCAGAAGTTTTATGTAAGTA
Long Flanking Sequence:
AACAACAGATAAATAGACAAATAGAAGGAAAGGAGAATTAATGGACTTAAAATTAGAATAGCCGAGAAACGCAGACATTGGGAATTTGTGGAAATAGCAATTACGAAACTTGTAATAATACAAGATGTTTCTAGAAAATAAACATTTTACATTTAACAACATACATTTAATTCATTTGTCATTAAATCATCCATCCAAGAAAATACATCAGTTGTCAAAAAAAAAAAAAAAAATTATTTATGATGACACAGAATAAGAGAGATGACTGCCAGTAAATGACTACCAACCCCTCCTCCGACAGCACAGGAAATTTAGCAAAATGGGGTATAAAATAAGGCACCCCAAGGAGCTCATCTGTACATCTTCTCACTTGTTGGCTGAAAATCAAGAAAGGATTAAGAAAAAAAAAGAAATTAAATATGATTTTCTCTGGAGTCATCCTTTCTGCTCTGCTCACGCTTCTTCTTTGCGACTGTGCTCAGAGCAGGAGAGTCGAATGC[A/T]AAACTGACTGTTGCTCATTTGTGGAGGGCTTTCCTTTAAGACTGAGGGAGCTCCGTTCTGCATACAAAGAAATTCAGAAGTTTTATGTAAGTACACTTCGACTGATCTCCAGCTGAATGAAATGCCAGTTTTGCAACTCCCATTTCTGCTTTTTGTGTGTTTATGTGAGTGTGTTGTATTGAAATCTGAGGTTCTTTCTAATAGATTTTTTTGTTGTTTACATTGCATCAGGAGTCCAACGATGACTTGGAACCATTATTAAATGAGGACATAAAACATAACATAAACGTAAGTGCCACTGATTTACTCCTACAGCACAACACCAGCAGTTATTCGCACTCAAAATTAGCAATAGCAGAACTAATCATAGTGAAACTGGGTAGGTTTTAAGCGAGTCTAAAATCTTGCGTAGCATCTTGCATCTGCACATTGCTACGGCAGTGTCGAAGTGTGACAACTGTGGGTGTCTGAAACAGCAGATAAAAAGGTAAATCTCTTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44739
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110673 Nonsense 170 180 5 5
Genomic Location (Zv9):
Chromosome 11 (position 21972647)
Other Location(s):
Assembly Chromosome Position
GRCz10 11 20978878
GRCz11 11 21139446
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGGGGGTCTATAAAGCTATGGGGGAGCTTGATTTGCTCTTTAGGTACATC[G/T]AGCAGTATCTAGCCTCAAAGAGGGTTAAGCACTAATAGGATGTTGCTGGG
Long Flanking Sequence:
TACTTTCAAGCAGGGAATTCTGCTCAAGATAGTCCATAGCTCATGAAAAAGATGATGCTAAAATGTAGTTATTTTACAAAAAGCGAAGTTTAGGCATCTTCAGAATGTCGTAATATAGAGAACATATGTAGAAAGTCTATGTGGCTTTTTTCTTGGCAAGAGCTGTTGGAAATGACCAAAATGCCTAGTGAGTGTTGCGAAATTGTTTGGTGAGGCAAAGTAGGTGTCTTTTACATTGCAAGCAACATGAAATAACACAAACGTCTATCTATGTTTGTTACAGAAGAGGTACTTTTCTTGCCAAAATCCCTTTGAAGTCAACAGCTTAAAGAATTCATATGAAAAGGTAAGTCTGATACATCAACATGAACATGATGATCATCAAATTTCATTTGAAAGCGATTGCAAAAATTGACATCTTTTTTTTTCTTTTCTGTTAGATGAAGGAAAAGGGGGTCTATAAAGCTATGGGGGAGCTTGATTTGCTCTTTAGGTACATC[G/T]AGCAGTATCTAGCCTCAAAGAGGGTTAAGCACTAATAGGATGTTGCTGGGTTGGACAGCGGCCAGTATCACTCTGTCTGAACATTCTGAAAACAGTATTGCATGGATGCAGTAAGACAAAGCACAAATGGACTTCATCCACAAATCTCTTGCACATCACCCACCCCGTCCATCCATCACACTACTGTTAGATGCACTGCAATGCCAGCCTCTTCATCTTCAGTGACTGGAGTTCTGGAAAAAGTCAATGTTTTAGATTTAACTAAAAGTATTATTAAGTCACATTGACCAGGCATGTTTTGAAATTTAGTTGTATTTTGTCAACTTGAAAAACATACTTATTATAAAGTACTAAAATAACTTATGAGATTATAATGTGCTTGACTTTGCATGAATGTTAATATTAATATTTAAGTCTTTTTGTGAGCTTTATTTATTTTGTGTGTTTCATGAGCTTAAAAGTTCGCTGTTTGTGTATTGTTATGCTTATATTTAAGTTGT
Associated Phenotype:
Not determined