Busch Lab

ZMP

chl1a

Ensembl ID:
ENSDARG00000077881
ZFIN ID:
ZDB-GENE-090313-201
Description:
cell adhesion molecule with homology to L1CAM (close homolog of L1) a [Source:RefSeq peptide;Acc:NP
Human Orthologue:
CHL1
Human Description:
cell adhesion molecule with homology to L1CAM (close homolog of L1) [Source:HGNC Symbol;Acc:1939]
Mouse Orthologue:
Chl1
Mouse Description:
cell adhesion molecule with homology to L1CAM Gene [Source:MGI Symbol;Acc:MGI:1098266]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa6728 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa18253 Nonsense Available for shipment Available now
sa14749 Essential Splice Site Available for shipment Available now
sa9665 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa6728
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111028 Essential Splice Site 128 1153 3 27
ENSDART00000113516 Essential Splice Site 128 1153 3 26
ENSDART00000135406 Essential Splice Site 128 1153 4 26

The following transcripts of ENSDARG00000077881 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 11487575)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 11446377
GRCz11 23 11381347
KASP Assay ID:
554-4867.1 (used for ordering genotyping assays)
KASP Sequence:
AACAAACTCGGAACTRCAACTTCAGAAGAAGCCGAATTTATTGTGCCTAG[T/C]AAGTCATAGTTCNNAYATATATATCACTCATTGTCTTGGCTTCTTAACTTGA
Long Flanking Sequence:
GTGGCTCAAAATATGCTCATCCATTTGGTCAAACAGGCAATAAAAGGGATAACTTGCAATTTCGAGTTTACTTCTCACAATTCTGAGAAAAAAAAAAAAAACAGATTTGCGAGTTTGAATCACACAATAGTGCCAAAATATACTTAAATATGTTTTTTTAATTTATTTTTAATTTTTTTTTTTTTTAATAGAGGCAGTAACTGGTTTCCATACACTTCAGAGAAGCTTTTACATTTGTAAATAAAACAAGAAAAATCAAATCATTAGTGTTATTAAAAGTTGCATGTTGTGTGATTTTAATCAAACAGGTTCCGCTGGACAAAAGATGGGATGGATTTTGACCCACATAAAGACCCTCAGGTCACTACAGAAGAAAATACTGGAACCTTTGAGATACCAAATAAAAAAGATAAAGTGAAATACCAGGGAAAGTACAGATGTTACGCCTCCAACAAACTCGGAACTGCAACTTCAGAAGAAGCCGAATTTATTGTGCCTAG[T/C]AAGTCATAGTTCATATATATATCACTCATTGTCTTGGCTTCTTAACTTGAATTTTTGCAATTCAAGTAATTTTCACAGGTCTGCTTCAGGATATTTGCATCTTTGCATGTGTGTACCCTTAAGCACATTCAACATGATGCTGCTCAACTTGTTTTTAGTCTTGACAATTTCTTAATGAACGCTTCGATGGTAGTCTGTCTCTAGGCTGAGGAAGTGAATATTAAAAGTTATTCATTTGTGTTGTTTTCATTCCTCCTCGCAGTGGTACCCAAGTTTCCCAAGGAGAAGATAGAGCCAATTGTGGTCACAGAGGGTGATTCGGTGGTTTTGGAGTGTAACCCGCCACAAGGGATTCCACCCTGGCAGCTGTACTGGATGACCAATGGTACAGTAAATTAAAGAGACTTTAAATTAGTTTGCTGTATTCTGCTTTACCCAAACAAAGGGATCCAATGAGATAATAATAATAATAATAATAATAATAATAATAATAATAATAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18253
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111028 Nonsense 188 1153 5 27
ENSDART00000113516 Nonsense 188 1153 5 26
ENSDART00000135406 Nonsense 188 1153 6 26

The following transcripts of ENSDARG00000077881 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 11493468)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 11452270
GRCz11 23 11387240
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CACATTGAGCAGAATGAGAGGGTGTCCATGGGCCTCAGTGGGAATCTGTA[C/A]TTCTCTAATAMGCTGGTGTCAGRCAGTCATGATGACTACTGCTGCTTYGC
Long Flanking Sequence:
AAATTAATGAACGAATGAAAGATATTGGATTTCAGGGTAATCTAATGACATTGATATTTGGTTAAGGCTTATAAAATACGTTTAAATAATCTCAATTGAGTCATTTCATTTTCCACCCATTGGCAAATATATAATTTAATTACCCTTTCCTCTAAAAGAAAAACATATTTTATCCAAGCTTCCTTCTGAAGTAAATAAAACTTAAGGATATTTATAGTTTGATTAAAAACCTCTTATTATTTCTGCACATATCTTCGCTTCCAGAGCTGAAGAGGCATCTTAATCACGATCCACCGAAATGTGAAGTGAGCTGCAGATTCTGAGCGCTTCCCATGATGTCTGTTATCTGCAGTTCAGCTGTCAGATGTACTGTTTCTGGCTGGTTTGGATGGATGTCCTGTTGCTCATGTTAATCTAAGCATGCTCTCTGTATTGTTCGCAGATCTCCGGCACATTGAGCAGAATGAGAGGGTGTCCATGGGCCTCAGTGGGAATCTGTA[C/A]TTCTCTAATACGCTGGTGTCAGACAGTCATGATGACTACTGCTGCTTCGCCTCCTTCTTCAAAATACGCACAATCGTCCAGAAACCCCGCATGGTCCTCAAGGTCAAGCCAGGTATTGAAATAATTCAAAGGATTTATGCGGTTCTATGTTATTTTATGTCACTGCAGTTTGGAGGTGTTATTTTTGAGAAATTGTAGAATGTGGCTATTATACATTGGCTTAGTTAATGAATTTGTAATGATTATCTTTAAACAAAAACATGTATTGCAGTAATTATAGTGTTTTACAGTTATTTAAGGTGTTAAGTTGTTAAACGCAAAAGAAAGAATTGTGAAAAATCGTAGTAACTAGACAGTGAATTAATAAAATGATAACATAAATAAATAAAAAATATTTAAATTAAAACGTTTTAGAGAGTTAGATGTTGTTTTTATACTCTGAGTTATATATATGATAACTCGGAGTATTAAAAACAACATCTAACTCCCTAAAACGTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14749
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111028 Essential Splice Site 332 1153 8 27
ENSDART00000113516 Essential Splice Site 332 1153 8 26
ENSDART00000135406 Essential Splice Site 332 1153 9 26

The following transcripts of ENSDARG00000077881 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 11497920)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 11456722
GRCz11 23 11391692
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
MAGAATCAGCATGGTGAAGATGTGCATCATTTCCAGGTCGAAGTAGARGG[T/A]AAGCTAACATTYACAAGGTYTTTAACCTGAATTTTACTCTGGTATTTGAG
Long Flanking Sequence:
TTCAATAATATGTATTTCTCATATTACTTTGGCCTATTTTGCTTGTTCAGACATCAAGGAAGGTTTTTTTGTATTATTATTCATGTCACGGCCATTTACTCTCATTTTCCCCCATTCAGTTCAGGAGAGGAAGCCAAGCATCTTGGTTCCCTCCAGTCATTCAACGACTTTCCTGAAAAAAGGAGAAGAGCTGGAGCTGGAGTGTATTGCAGAAGGACTGTGAGTTCAACAAGGGTTTACAAATATTACACAGCTGCAAAGCTTTTCTACCGACAGAGAGACAGCGAGTGTGAGAGAGTATGCTGGTGTTTTCTCAGGCCTACACCGGAGGTAGAATGGATCAAGATATGGGGTGACTTACCAAAGCGCACGCAGATAAAGAACTTCGGAAAGCTTCTGACAATACCAAACATCAGAGAAGAGGACGAAGGAAAATACATGTGTAAAGCCAAGAATCAGCATGGTGAAGATGTGCATCATTTCCAGGTCGAAGTAGAGGG[T/A]AAGCTAACATTCACAAGGTCTTTAACCTGAATTTTACTCTGGTATTTGAGGATTCTCAGGAATTCCAATTCATAAATCTGTTTGACATAAAAGCTATCTATCTATCTATCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGTCTGCCTGCCTGCCTGCCTGCCTGCCTGCCTGCCTGCCTGCCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCAACTAATCTGTCCACCTGTCTGTCCGTTCATCTATCTGTGCATCTATCATCCATCTGCCAATCTGCTGTATATTTCATTCATTTATATTTATATAAAAATGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9665
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111028 Nonsense 369 1153 9 27
ENSDART00000113516 Nonsense 369 1153 9 26
ENSDART00000135406 Nonsense 369 1153 10 26

The following transcripts of ENSDARG00000077881 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 23 (position 11498736)
Other Location(s):
Assembly Chromosome Position
GRCz10 23 11457538
GRCz11 23 11392508
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCCACATCAACTGTTCTGCTACCGGAAAACCGCAACCCACAATCACCTGG[A/T]AAAGAAACGGCAAGCCCCTCGATGGTGTGTTRAACCCCCTCCTCTCAACC
Long Flanking Sequence:
ATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCTATCAACTAATCTGTCCACCTGTCTGTCCGTTCATCTATCTGTGCATCTATCATCCATCTGCCAATCTGCTGTATATTTCATTCATTTATATTTATATAAAAATGTTTAGCAGGTTTACTTCATTTATGAATCATAATAGCGTTTATTGCACCAAACATAATCTTAATGAAAATCAATTTGATCTTAAAAGACCATTAGCGCCAAGTGAAATCCTGTACATGAAAAATGATGTCACTTTTAAACACAGGAGGGCAGTATTGCTTTAAGTTAGAGTGTTGTTTTAATGGTATTTATATGGTGTGTGTCTCAGAGCCACCGAGCTGGCAGAAGGAGCCGCTGAAGAGTCAGTTAGCATGGATTGGATCTGACATCCACATCAACTGTTCTGCTACCGGAAAACCGCAACCCACAATCACCTGG[A/T]AAAGAAACGGCAAGCCCCTCGATGGTGTGTTGAACCCCCTCCTCTCAACCCTTATCAGGCCCATTTGACTGAATTTGTCGGTTCAAAGCCACTGCCAAATGTGCAATTACTGGCTTTGAAAACAGTCTGTTGTTGCTTTCTGGTTTGCTCATTATTAAGAGTTTGTAAACAGCAGTGCATTTCTGGCCACTCCGTGTTGATGCTAAATTTGCATGCTCTAGTAAAATCATTATGTGCATCATACAGCAACAATTTAATGGTGTATCTTAAAAATATGTTAGTTATTACAAGTTTATTGTCACTATAATGACATGGAATATTGCAATAAACAACAGCCAAGGGCTTCTTTAGGTCAAATGGAAATTTTAAAAAGTAATTTTTATGGATGAAATCTTAAATTTAGCCATATGTATTGTTGAAGTGAGAATTATAAGCCCTACTGTTAAACTTTTGCTCTTTTATATTTTATTTTATTTTTCTCAATTTCTGTTTACAAAGAG
Associated Phenotype:
Not determined