ZMP

ARHGEF10

Ensembl ID:

ENSDARG00000077788

Description:

Rho guanine nucleotide exchange factor (GEF) 10 [Source:HGNC Symbol;Acc:14103]

Human Orthologue:

ARHGEF10

Human Description:

Rho guanine nucleotide exchange factor (GEF) 10 [Source:HGNC Symbol;Acc:14103]

Mouse Orthologue:

Arhgef10

Mouse Description:

Rho guanine nucleotide exchange factor (GEF) 10 Gene [Source:MGI Symbol;Acc:MGI:2444453]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa23085	Nonsense	Available for shipment	Available now
sa28858	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa23085

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

G > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000110451	Nonsense	188	1239	3	26

Genomic Location (Zv9):

Chromosome 17 (position 25055228)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	17	25208670
GRCz11	17	25227071

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TGCCATCAGAGCAGAGCGGTCCGCCCTCCTCTCCCTCAGCCAATCAGATT[G/T]AAGGAGTTGTTCAGGATGTGTTAGGTAGCCCAGGGTTGTCCTCTGGGTAT

Long Flanking Sequence:

AGTATGGCCTTATCATTTCACCTACAACAGCTTTGCATATAACTGCTTGGAAATCAAATCTACAGTCTTTTTGGTGGCATTCGCTTGCTTTTTTTCCTGAAATGGTTTCTGAGGTTGCATCTGTCTTTTTATCTCTCTCAGTCTACCCTCTTCTCTTATCTCTAACCCTAAATAAAGTTTTGAATATGACTTCTTTCTTTCAGGAATTCCTCCCACATATATTTCATAAGATCTTATTAGCTGAATTTAACTCTAAACAAACAACAACACATAAGATTTCTGTGTAAGACGATACAGTTTTCCTACAGGGCCCGGATTGTCTCAGGCATTTTTGAATAAGTCACTGTACTTTCTGATCACTAGAAAACAAAGGTGCCAGTGTGGTTTGCTCCTCCAAGCCCAAAGTGAGCCCCTACTCTGTGATCGACATCGGCCCCATCCAACAGCAGCTGCCATCAGAGCAGAGCGGTCCGCCCTCCTCTCCCTCAGCCAATCAGATT[G/T]AAGGAGTTGTTCAGGATGTGTTAGGTAGCCCAGGGTTGTCCTCTGGGTATTCAGTGCCAGTGCCCTGTGGTTATGCAACGCCTTCAAATGTGCCAGTGATCCCACCAACCTACACCACCCCAGTTCTCATCCGCCACTTCTCTATGGATGAAGATGGTAAAGAAAGGCATTTTCCCCGTCTCTTTCTATTTTATTTTATTTATTTATTTATTTATTTCGGGAGAGGGCTTCACCTTCACTATACATATTCCCTCTCTTTGTGATTTTCTTCTTTCATGCTCTCCTGCTTTTGTTTTTCTGATGTTTTGCCATGAGGAAGTTGGGGGTAAATTTAGCTGTGGCGTTGGCTGTGATGAGGTTTCCTGTGTTTTTTTTTTTTTTTTTTTTTTTGCAAAGTGTAATAGCAGCCTGATTGTTATCCAGTGTCAAAAGTATACCATACAACATTTTTAGCTTTTTTTTAATAATTGATAGCTTGATTTTAAATGTTATTTTAAACT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa28858

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000110451	Essential Splice Site	883	1239	19	26

Genomic Location (Zv9):

Chromosome 17 (position 25077411)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	17	25230853
GRCz11	17	25249254

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CAGCTGATCGCTGTAGGATACAACTACAGTTACCAGGGAAACAAGACAAG[T/A]ATGTGTGACCTACACTTTACACTAAAGAAAGCCCACACTAAAAAGTTTGG

Long Flanking Sequence:

ACCAGAGTTTAATGATTCACTCTAGAATATGATTCAGTTTCAGCTGTATTGCTCCCAGCTAATGAGGAGGGTTTTTCAATTCACCCTAACTAAATGAACAGAACGGTGATGTTCATTATTTAAGCTTAAACATGCACAGATGAGTCTTTATTGTCTTTGTCTTATTTGCAGATAAGTTATATATGGGGCCGGGACAGCTGTATCAGGACCTGCAGAACCTGATCCATGACCTGGGCTTGGTGAACCAAATTTCCACCATGATCAGCAGTCTGAAAGGGAATTATCAGGTGAATTGTTCAGACCACCGTTAAACACTTTTGGGTTGATGATTAAAGACTGATAGTTGATTTGTGACTCTATTCTTTCTCCAGAATGTTAATGGGACTGTTGCTCAGGACTGGGTTTCAGGTCTTCAGCGTCTCATTTTAAAGAAAGAGGAGGAGATTCGGGCAGCTGATCGCTGTAGGATACAACTACAGTTACCAGGGAAACAAGACAAG[T/A]ATGTGTGACCTACACTTTACACTAAAGAAAGCCCACACTAAAAAGTTTGGGTTCAGATTGCCATAATGCGAGAAATGTTGAGAAATTTCATCACAAATGAAAACAATTATTTAATAATTCCTGTAACAGCAAAGCTAATGATCTTGCTGTCATTTTTGAACATTTAAAAGGGATAGTTCACCAACAAATACAATTTTACAATTTACTCACTCTTAAGTGGTTCCAAACCTTAATGAATTTCTTTTATTTCTGTTGAACACAAAAGAAGATATATTGAAGAATGTACAAAACCAGCAACTACTGACATCCATAGTAGGAAAAATATTGACTATGTAAGTCAATGGTTACTGGTTTTTAACCTTCTTCGGAAAATCTTCTTTTGATTTCAACAGAATCGAGAAACTCAAAATGTTGTGTGACAAGGGTGAGTAAAGGCTTTAATGTGTTTTACTAAATTAATGTTTTAAAGGTAAATTCATTTATTTGTTTGTTTGAAGACT

Associated Phenotype:

Not determined