Busch Lab

ZMP

si:ch211-71k24.5

Ensembl ID:
ENSDARG00000077656
ZFIN ID:
ZDB-GENE-081107-37
Description:
Novel protein similar to vertebrate brefeldin A-inhibited guanine nucleotide-exchange protein 3 (KIA
Human Orthologue:
KIAA1244
Human Description:
KIAA1244 [Source:HGNC Symbol;Acc:21213]
Mouse Orthologue:
D10Bwg1379e
Mouse Description:
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed Gene [Source:MGI Symbol;Acc:MGI:10638

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa42119 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa22200 Nonsense Available for shipment Available now
sa16643 Essential Splice Site, Missense Available for shipment Available now
sa44780 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa13753 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa42119
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114456 Essential Splice Site 141 1717 None 32
ENSDART00000137124 None None 1352 None 23
ENSDART00000146355 Essential Splice Site 136 176 None 6
Genomic Location (Zv9):
Chromosome 13 (position 2233155)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 2200819
GRCz11 13 2453206
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTAAGATTTGTCATTAGGATTTGCTGAAAATCTGTGTTGTTGTTTCTCT[A/T]GGTATGTATAGAGACGTATATATCCAGTTGTCATCAGCGCAGTATCAACA
Long Flanking Sequence:
TTGGGTCAGTTTTCTGTGTGGAGTTTGCATGTTCTGCCCGTGTTTGTGTGGGTTTCTTCCTGGTGCTCTGGTTTCCCCCACAGTCCAAACACATGCGCTATAAGGGAATTGATTAAACTAAATTACCCGTTGTGTATGAATGCGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGAATGAGTTGGAGGAGGAGTCTGTTGTAATAACTCTCTGCAAACACATTACCCCATATTTATGAAATGCCTACTTTACTACATCCAATCAGCTCGCAGCAGAAAAAACAAGCCACACCCACTGTTTTCTCATTTAATATTCCGTTTCTCTAGGAACTGCGTCTCAATATGGAAAAAAATAAACGGTCGCAGCTTCCGGTTCATGCAGACTATCTTCTCTGTACTCCACATACTCAATATAATCTCTGTACTCCACTGTAAATGAGGCTAACTTTTTAAGATTTGTCATTAGGATTTGCTGAAAATCTGTGTTGTTGTTTCTCT[A/T]GGTATGTATAGAGACGTATATATCCAGTTGTCATCAGCGCAGTATCAACACGGCGGTCAGAGCCACTCTCAGCCAGATTCTTGGAGACCTCACTCTACAGCTACGCCATAGACAAGAAAACACAGTGAGTCACGTGCTATAAGACTTCAACTGAGCTTCAATAAAAACAAACGCATGTCTATACAGAATGTCAGTGGTGGGATTCTGTGCACACATAATTTACAATAAGGTCTCATTTGTTTATTGAAACGGTTTAATCTGCAAAAACAACCCTCCTGAATATACTTTATCCGGTTTGTTACACTGCTACTTGCTACAAAACATAGACATTAGACACAAAACATTGTTCTGAGCCATAATAGTTTATGAATTCTTTAATTAAACACAAAACTGATAGAAACGTAACTGGCTGAATGGAGTATACACTAACCTGCGCATTTTTCAGACAGTCAAAAAAAGTCAAAACATGACAGACAAGCAGATACAAACTGTATGATTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22200
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114456 Nonsense 482 1717 12 32
ENSDART00000137124 Nonsense 254 1352 4 23
ENSDART00000146355 None None 176 None 6
Genomic Location (Zv9):
Chromosome 13 (position 2240610)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 2193364
GRCz11 13 2460661
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCGGAGTCAATGCGTGAGTCTGTGGAAGTCAACGAAGCGGACTTCCGCTG[G/A]CAGCGGCGAGTGCTCTCATCCGAAAACGCTGCATGGGAGGCGAGCATTAC
Long Flanking Sequence:
ATAAACAGGTTAACTCTTCTAATAAGCATGTTGTTGTTTTCCCTCATTCTCCCAGATTGTGGGAAGCCCCCAGCGCTTGTTTGACCTCGCCGGTCCATGCGTGATTGAACACGAGACGAGAAAGAGGTCTTTCTCCAAAAGGAAATCACATCTCGATCTTCTCAAACTGTAAGATGTTTTGTATAAAATTCAGTGATGATCTAGTTACTATATTGGAGATCTTAAAAATCTGTTGTGTGTCTCCAATGAGTGATTCGTCTTTCCTAATTTCCCAGCGTAATGGATGGCATCACAGAAGCGTGTATGAAGGGTGGGATTGAGGCCTGTTACTCCTCCGTCTCCTGCGCCGGGGCCCTATTAGGTGCCTTGGATGAGCTCAGTCAGGGGCGTGGCCTGCAGCAGGACCAGACCCGCATGCTGCTGCGCCGATTGGAGGAGCTCAAGGAAGGGGCGGAGTCAATGCGTGAGTCTGTGGAAGTCAACGAAGCGGACTTCCGCTG[G/A]CAGCGGCGAGTGCTCTCATCCGAAAACGCTGCATGGGAGGCGAGCATTACCGAACGCAGCCCTGACATTAGCATTAGCGTCACCACCGACACAGGCCAGACCACTTTGGAAGGGGATGTAGGGCAGACTACGCTTGAAGGGGATATGGGGAGGACCACTCCTGAAGATTGCGGGGACGAACCGCGACTACCTTCGCCTACCTGTGGATCTCGTCAGGAGTGTGTCGCACCTGAAATCTCATCCTCTACGGCTCCTCCTGACGTAGTGCAACGCAGCCATGGCCTAGCCTATCCTGACATCACCAACTTCTTATCGGTGGAGTCCCGGACGCGTTCGCATGGCTCCCGATACAGCGAGAGTAACTTCAGTGCCGACGAGCAGGAGCTGTCCAGAACAGAGTTTGACTCCTGTGATCAGTACTCCATGGCTGCAGAAAAGGACTCCGGACGGTCTGATGTATCCGATATGGGCTCTGATAACTGCTCATTGGCTGATGAGGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16643
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114456 Missense 509 1717 12 32
ENSDART00000137124 Essential Splice Site 280 1352 4 23
ENSDART00000146355 None None 176 None 6
Genomic Location (Zv9):
Chromosome 13 (position 2240689)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 2193285
GRCz11 13 2460740
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGCATGGGAGGCGRGCATTACCGAACGCAGCCCTGAMATTAGCATTAGC[G/A]TCACCACCGACACAGGCCAGACCACTTTGGAAGGGGATGTAGGGCAGACT
Long Flanking Sequence:
TTTGACCTCGCCGGTCCATGCGTGATTGAACACGAGACGAGAAAGAGGTCTTTCTCCAAAAGGAAATCACATCTCGATCTTCTCAAACTGTAAGATGTTTTGTATAAAATTCAGTGATGATCTAGTTACTATATTGGAGATCTTAAAAATCTGTTGTGTGTCTCCAATGAGTGATTCGTCTTTCCTAATTTCCCAGCGTAATGGATGGCATCACAGAAGCGTGTATGAAGGGTGGGATTGAGGCCTGTTACTCCTCCGTCTCCTGCGCCGGGGCCCTATTAGGTGCCTTGGATGAGCTCAGTCAGGGGCGTGGCCTGCAGCAGGACCAGACCCGCATGCTGCTGCGCCGATTGGAGGAGCTCAAGGAAGGGGCGGAGTCAATGCGTGAGTCTGTGGAAGTCAACGAAGCGGACTTCCGCTGGCAGCGGCGAGTGCTCTCATCCGAAAACGCTGCATGGGAGGCGAGCATTACCGAACGCAGCCCTGACATTAGCATTAGC[G/A]TCACCACCGACACAGGCCAGACCACTTTGGAAGGGGATGTAGGGCAGACTACGCTTGAAGGGGATATGGGGAGGACCACTCCTGAAGATTGCGGGGACGAACCGCGACTACCTTCGCCTACCTGTGGATCTCGTCAGGAGTGTGTCGCACCTGAAATCTCATCCTCTACGGCTCCTCCTGACGTAGTGCAACGCAGCCATGGCCTAGCCTATCCTGACATCACCAACTTCTTATCGGTGGAGTCCCGGACGCGTTCGCATGGCTCCCGATACAGCGAGAGTAACTTCAGTGCCGACGAGCAGGAGCTGTCCAGAACAGAGTTTGACTCCTGTGATCAGTACTCCATGGCTGCAGAAAAGGACTCCGGACGGTCTGATGTATCCGATATGGGCTCTGATAACTGCTCATTGGCTGATGAGGAGCAGACGCCGCGGGACTGTCCCGGCCACCGTACACTGCGGACTGCAGCTTTGTCTTTAAAGCTGCTGAAGAACCAGGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44780
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114456 Essential Splice Site 977 1717 17 32
ENSDART00000137124 Essential Splice Site 700 1352 10 23
ENSDART00000146355 None None 176 None 6
Genomic Location (Zv9):
Chromosome 13 (position 2249129)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 2184845
GRCz11 13 2469180
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGACAAAGAGGAGAAAGAATTAGGAGACACTGGAGATGCCATTACTCAAG[G/A]TACACTCACACATTTCACATAAACCGCGATCACAGTCATGCATAGGGATG
Long Flanking Sequence:
ATACCTGTTTTATCTGACCCCATGCTCAATAATGTTCATGTATGGTGACTGGGCTGGCCAATCCTGGAGCAGCTTGACCTTCTTTGCTTTCAGGAGCTTTGATGTGGAGGCTGAATCTTCCACTTTGCAGATCTTGCACGTACTGAATGAAACCCCAAACCATGATTTCTCCTTCACCAAACTTGACTGATTTCTGTAAGAATCTTCAGTCCATGCTGGTTCCAGTAGGTCTTCATCGAAAAAAATCGACCTTCTGCCACTTTTCCAGATGATCCGCTAGAAGTCAAGTTATTATTGGTTGCTCTTACAACTGAGATCCATGACAAGGCTTTTGTCAGGTAGTGCAGGACATTAATGTGTCTGCTGGGCCTTCATTCTCTGTTATCCAGGGGTGGCAGCCAACTGTGCTTCAGCACTGGCGCAGATGGCAGCGGCTTCATGTGTTCAGGAGGACAAAGAGGAGAAAGAATTAGGAGACACTGGAGATGCCATTACTCAAG[G/A]TACACTCACACATTTCACATAAACCGCGATCACAGTCATGCATAGGGATGACATATTGGCAGAGCCAGACAGAATCTGCATTTTGTTTACCCCATCTGTGCAGAATTGTCTGAAAAGTGAAGTTTATGTATAAACTAATTTCGAGAGGATCACGTGCTTATGATTGCTAGCGGCTGGATCCCATTATCCAATTCACTACGCTCTAATCAGATGACTCCTAAACTACTATAAATACCCTGGGTTTCATTCCACTGCTATCTTCGTTTTGAAGAGTCCCCCCTTCCACCCCTAATCCTCCTTCTTAGATGGGTGACACGGTGGCCCAGTGCGTAGCACTGTCGCCTCACAGCAAGAATGTCTCTGGTTCCAGGCTTTACCAAACCAGCTGACATTTCTGTGTGGAGTTTGCACTTCTCCCCGTGCTCACGTGGGTTTCTTCCGGGTTCCCCGGTTTCCTCCCACCGTCTAAAAACATGCAATTAAGTTAATTGACTAATCCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa13753
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114456 Nonsense 1251 1717 22 32
ENSDART00000137124 Nonsense 974 1352 15 23
ENSDART00000146355 None None 176 None 6
Genomic Location (Zv9):
Chromosome 13 (position 2258289)
Other Location(s):
Assembly Chromosome Position
GRCz10 13 2175685
GRCz11 13 2478340
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAGGCCGTGTCCTTCATCCATGATGTCCTGATGGAGGTTTTGAGCAGCTG[G/A]CCGGAGCTGCCGCATTTTCACTTCAATGAGGCTCTTTTCAGRCCGTTTGA
Long Flanking Sequence:
GTGAAGAACAAGAGCAGGCCGCTGCTGCACATGATGAGAGCCTGGAGCGTTGTAGCACCACACCTGGTGGAGGTTTGTGCCCCTTTTTACAAGACGTAAAATAAGTCTCTGATGTCCCTTAGAGTGTGTTTGTGAAGTTTCAGCTCATAATACCACACAAATAATGTCTGATAACTGCCTCCTGTAGGCTTTGATCCTAATTGTGTCGTTTTGGTGACTGTCGCTTTAAATTCAAATGAGATTGTGCTCTTTTTAAAAGTGGGCGGAGTGTAAGCATAGTGGCAGACTCAAAAACAAGACAGAACTTGGGGGGAAAATATAATAATTCAGGAGGGCAAATAACTCTGACTTAACTGTTAATGCACATCTATATTATTGAGGTTTTCAGATTCCAACTCTTTGACCTGTTCCCCACAGGCGGCCTGTCACAAGGAGCGCCACGTGTCCCAGAAGGCCGTGTCCTTCATCCATGATGTCCTGATGGAGGTTTTGAGCAGCTG[G/A]CCGGAGCTGCCGCATTTTCACTTCAATGAGGCTCTTTTCAGACCGTTTGAGCACATCATGCAGCTGGAGCTCTGCGATGAAGACGTCCAGGATCAGGTCAGGATCCACGCACTGAATTAGACTTATAATGCATTCAGCAAAAACCCTGCAGTCACTCGTCAGACAAAATCTGTAGATATTATTAGCTATTTCTGTGCAGGATCTGAAGATTTGATTTTTTAGAGTTTAGTAAATACAAACAACACATAAAAAAAATAATAATAATAAATAAATAAATAAATAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACACACACACACACACACACACACACACACACACACACACACACACACACATATATGTGTATATAGTTGAAAATTTATTTAATATTTTTTAATAATATGTCAAAATTATTTAATTTTTTTTTTTTCTTTTTCAAATATTTCCCAA
Associated Phenotype:
Not determined