Busch Lab

ZMP

ENSDARG00000076924

Ensembl ID:
ENSDARG00000076924
Mouse Orthologue:
Als2
Mouse Description:
amyotrophic lateral sclerosis 2 (juvenile) homolog (human) Gene [Source:MGI Symbol;Acc:MGI:1921268]

Alleles

There are 9 alleles of this gene:

Allele Name Consequence Status Availability
sa15114 Nonsense Available for shipment Available now
sa33807 Nonsense Mutation detected in F1 DNA Not yet available
sa15705 Essential Splice Site Available for shipment Available now
sa33806 Nonsense Mutation detected in F1 DNA Not yet available
sa12310 Essential Splice Site Available for shipment Available now

Mutation Details

Allele Name:
sa15114
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108524 Nonsense 87 1658 3 37
Genomic Location (Zv9):
Chromosome 6 (position 7927698)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 9563367
GRCz11 6 9798906
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGAACCAAAYATCATCAGCAGAGCCCATTTTGGAGGCAGTGCTGAGCGAA[C/T]AGCGTGTTGTTTTTGTGGCTGCTGGCTCCGCSCACAGCGGAGTYGTGACG
Long Flanking Sequence:
ATGTATTAGAAGAAAAAGCCTTATTATTATAATTATTATTATTATAATTATAAAAATATGATTTAGTTGTTTAATTTAACAAATTACAATAAAGTACAAATAAAATCATAACTAATCATGTGATTTTGTTAGCTCACATTGTTAGTTTTGTGGCGAACAATTCATCTGTGTCACTGTGTCACAATATAAAAAAAAAAACAGTTGCAGCTTCCGGTTCATGCAGACTTTAACAATTATATTAATATATTTATTTAAAAAGGCTAAAGCATCCTAGGGTTCCCTTAGAAGTTAATTGGGGCCCCCTAGTTTGCACTGGCCCCTGTTTCATAAAAGTTGTTTTTAAAAAATTGATGATTTAGAAAAAAATTATGTTACAATTCAGAAATGTACTAATTTGAATTCTATATTTAGGCGGACAAGTGTACAGTTTTGGTGAGTTGCCTTGGAAGCAGAACCAAACATCATCAGCAGAGCCCATTTTGGAGGCAGTGCTGAGCGAA[C/T]AGCGTGTTGTTTTTGTGGCTGCTGGCTCCGCCCACAGCGGAGTCGTGACGGAGGATGGAGGAGTGCACATGTGGGGAGAAAATGTTCACGGCCAGTGTGGCTTGTTGGGACTGTCTGTTATCCCTAACCCCACCCCTGTGGGTGTGCTTGACTCTGAGGCCACGCCACCTCAGACGGTTAAAATCCTGGAGGTGGCATGTGGCGATCAGCACACCCTGGCTCTTTCAGCCAAGCATGAAGTCTGGGCTTGGGGTAGCGGCTGCCAGCTGGGCCTCAACACTTCAACTTTTCCCGTCTGGAAGCCCCAAAAAGTGGACCACCTATCTGGGAGGCATGTATTACAGGTGGCGTGTGGATCCGCTCACAGCGTGGCTCTCGTACGCTGTCTCCCTCCTCCACAGGAGCCCCGAAAACCCCCTCAAGACAAATGCGGTCAGTGCCATCAGCTGCTCTACACTATGACAGATAAAGAAGACCATGTCATTATCTCTGACGGCCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33807
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108524 Nonsense 531 1658 8 37
Genomic Location (Zv9):
Chromosome 6 (position 7916871)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 9574194
GRCz11 6 9809733
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGACTGATGCCCACCTGCCTTCCTTACAGACGGAAGTGTGGAGCTGGGGA[C/T]AAGGCCAGGATGGACAACTTGGACATGGAGACCTCCTTCCCAGGTCAGAG
Long Flanking Sequence:
GTAAAATCTTACCGAAATACGATTAAATATGGTGGGATTCCAATCTGATATGCACAAAAATAGGATTTGGTTTGTTGATTTGGACAATCTTTATAAGATCTACTGTTTGTATATAAATGAGTAAAAAACAATACAAATGCATATTTATTTTTAACCTCACATGATTATATCACAACATATATCAATCAAATGTTTGAGCGGATGTGTGGTTAATTTTAAAGCAGAAAAATCAGATTTGCACTTTGAACAATCTGAACAAGGCTTTCTGTCTTATTAGTACATGTAGAATACATTCAGGCTTTAGATATTAATGTTGCAGGTTTCTTTTAAGGTGTTTTGTGTTGTTGATTCTCTTTCTCCTTCACACTCTCTCAGTATCTCCTCGCCTCCTACGGAGAACAAGTCGCCCCCGTATGCGGGCTGTCCCGCTCGCTTCAGGAGGTATACCTGAGACTGATGCCCACCTGCCTTCCTTACAGACGGAAGTGTGGAGCTGGGGA[C/T]AAGGCCAGGATGGACAACTTGGACATGGAGACCTCCTTCCCAGGTCAGAGTCTTTAAAATCAGCGGGGAGCCATGTGTAGCTCCAATCTTTCCTAACACGTTAGCAACTTAATACAATGTTAGCAACTTGTTAAAAGTGTTACCAATATCCATAAACATGGTCAAATATCCTTGCAACTTATGTTTTTGACTTATTCAAGCATTACACATTCGTTAAAACAAGTTCAGTTGTTAAAATAGTAGCATTTTAGTAGAACATGCTAAAATATGCTAACATTATGTCAAAAAAATGGCAGAAACATTCTACCAAAATCTCAAAACCTACTAATATTTTAAAACGTTAGTGTTACGGAAATGCTAAAAACATGCTATCATAGAACATGCTAACGTTTTGACTAAACAGGAATTGGCTACTGTATACTAGAACATGTTATTAATGTGCCTAGTAAAACAAATTGGCAAACATGCTAAAATTGCTAGCAACTTGTTAAAATGTAAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa15705
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108524 Essential Splice Site 604 1658 11 37
Genomic Location (Zv9):
Chromosome 6 (position 7908884)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 9582181
GRCz11 6 9817720
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCAGATTCCTGACTGTTTTGCTTTTTGTWTSTCCTCTTTTGTCTTTGCGC[A/T]GCTGTCAGATGGGATTCRTGTGTGGGATATTGGGGCAGGTCWGCAGCACA
Long Flanking Sequence:
CTAGGTAATTAGGTTAACTAGGCAGGTCAGGGTAATTAGGCAAGTTATTGTATATTGATGGTTTGTTCTGTAGACTATCGAAACAATATAGCTTAAAGGGGCTAATAATTTTGACCTTAAAATGTTTTTAAAAAAATTAAAAACTGCTTTTATTCCTGCCTAAATAAACCAAACAAGACTTTCTCTAGAAGAAAAAATATTATCAGACATACTGTGAAAATTTCCTTGCTCTGTTAAACATAATTTGGGAAATATTTAAAAAAGAAAAACAAACTCAAAGTGGGCTAATAATTCTGACTTCAACTGTATATGTTTGTTTGTGTGTCATCTCTTTATGAAGTATGAAGTTGTTCTTATCATGTAATGTTTTTATGTATATTGATCTTACTATGAAATTGCCATAAGTGGCTGATGTGTCAATAAATGAATGAATGAATGAATGGACAACATCCAGATTCCTGACTGTTTTGCTTTTTGTTTGTCCTCTTTTGTCTTTGCGC[A/T]GCTGTCAGATGGGATTCGTGTGTGGGATATTGGGGCAGGTCTGCAGCACACTCTCTTATTGGCTGACGGAGACTGTATTCAGCCAATCCTGTACTACAGCGGACAGCAGGTGAAGGAAGTGCCGGAGCCAACAGAGGAAGAGGAGCAGACTGCAGAATACACGCAACAACCTGTGCTGCTGCCCTTCTGTATGAACGTGAGCAAGTCTTCTCATCATCAACATCACTTCAAATCATTTTTTTTTTGTAGGGATGGACGATTAATCGATAAAAAAAAAATGCAGTCTAGATTCAGATACTGATGCAGTGTTGAATATAAACGGTCTCAATTTCATCTTTAATATTCCTTCTATAATCAAACTGTACATTTAAATCTGCGTTAGAACCAGAGTCATTTCTACCAGCATTATTATTATTTCTTATACTGATGTTTTAATTATCACAAAAGTACTGGAATAATAGTTATGTCATGAACACTGATGCTTACATGAAGATTTAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33806
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108524 Nonsense 688 1658 12 37
Genomic Location (Zv9):
Chromosome 6 (position 7907154)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 9583911
GRCz11 6 9819450
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTAAGCAGTGTGTATGCAGGTGGACGGACGTGTGCAGCGCTGACGGATTG[T/A]AATGTCATGGGTTTTATTGCTAGTCTGCATGAGCTGGCGGCTGCAGAGAG
Long Flanking Sequence:
GCGGTGGCATGACATTAAAAAGGTGGTTTGTGCTCAAAAATCCTTTATTGTGGCTGAATTCCAACAATTCAGAAAAGATGAATGACCAAAATTTGGAGTCAAAATTGTAGCCTTTGGAGAGGCCTAGTCATAGTCCTGACCTGAATCCAATTGAAATGCTGTGGTATGACACTAAAAAGGTGGTTTGTGCTCAAAAATCCTTCATTGTGACTGAACTCCAACAATTTTGAAAAGACGACTCAGCCAAAATTCCTCCACAGTGCTGTAACAGACTCGTTGCAAGTTATTGAAAATGCTTGGTTGCAGTTGATGCTGCTAAGGGGAATCAACCAAAATTGTTCCCTGATTGTTTCAATTATTATTGTATTATGAATTCTTTACCTTGATGTGGTGTTATCACTATTGTTTGAGTTGACTCTACATGATCTTTTTGTGTTGCAGTTGGGCTATGTAAGCAGTGTGTATGCAGGTGGACGGACGTGTGCAGCGCTGACGGATTG[T/A]AATGTCATGGGTTTTATTGCTAGTCTGCATGAGCTGGCGGCTGCAGAGAGAAAATATTACTGCAAACTCAGCAATATCAAGAGTCTTCTGCTCCAGCCATTGCTCAAGCTGGGTATGACTGTGTGTGTCACAATTGCTTGTTTTGTACACTGATTTAGACCTTCATTTGCATCTTCATTATAGCCCTGGAAATCTACACAAGTATCGTCTTATTCAGCGGCACATTTAGTGGAAATAAAACAGCTGAAATCAATGCTTAGTATATGCAAACGCTTTTGTTAACTAAAACTATATATATATATATATATATATATATATATATATATATATATATATATATATATAATTTAATTTATAATGTAAAACGTAATATTAGCATTAAGGGTATTACCCTTAACTAGAACTATTAACATTTTACATATAAAAATATAGCATATAAACCATTTTACTGGAGATATTGAGTTTATGTGCTTACCAATGAACAAATGATATCTGTTGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa12310
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108524 Essential Splice Site 1467 1658 31 37
Genomic Location (Zv9):
Chromosome 6 (position 7879804)
Other Location(s):
Assembly Chromosome Position
GRCz10 6 9611243
GRCz11 6 9846782
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGRTCGGCACAGAYGCTGATGGAAAGCTGCTGGAGTCTCCTAAACCTGGG[T/A]ATGGAAAATAGTATTAAAGGACTCTAAGGGTGGTCTATGCAACWGCAGTT
Long Flanking Sequence:
CCGTCGGTACCTGGTGAAGGTAAACATTGTATTTATTAACTGATGCTAAACCACACTTTCCTCCAACACATTAGCTTCCTAGTGTATATTTACCACTTTTGTACCACTGATTATTTTGCTCTGTATATCACAGACGCATGATGTGTGTTTTATTTTAGGCATGTGATACTCCTCTGCATCCTCTGGGTCGGCTGGTGGAGACGCTGGTTTCGGTATACCGGATGACGTATGTTGGTGTTGGAGCAAACCGCAGGTTATTACCGCAGGCCGTCAATGAGATCACGTCCTATCTCAGCCGTATCTTCCAGCTCGTCAGGTAAGATGATCTGTAAAACAGAAAAGGAAGTGTGCTTTTCCATGTCTTTTAAATAACATGCTTGTTTGTGTTTAGATTTCTCTTTCCCGAACTGCCAGAAGAAGGAGGTTCACTAGCCGACCCTCCAAAAGAGAAGGTCGGCACAGATGCTGATGGAAAGCTGCTGGAGTCTCCTAAACCTGGG[T/A]ATGGAAAATAGTATTAAAGGACTCTAAGGGTGGTCTATGCAACTGCAGTTGTTCATATTACAATTAGCTTTTAACTGGAATGTAAAAAAAAAACATTCTTCATTCATTTTCCTTCGGCTTAGTCCCTTTATTTATCAGGGGTCGCCACAGCGGAATGAACCGCCAACTTATCTAGCAAATGTTTTACCCAGTACTGGGAAACATCCACACACACTTGTTCACACACATACACTACGGCCAGTTTAGTTTAAGCAATTCACCTGTATCTCATGTCTTTGGACTGTGAGGAAACTGGAGCACCCGGAGGAAACCCATGCAAACATGGGGAGAACATGCAAATCTCACAAAGAAATGCCAACTGAGCCAGCCGGTACTCGAGCCAACGACCTTCTTGCTGTGAGGAGACAGCGCTAACCAATGAACCACTGTATCGCCTTGGTTAATCATAATTATGGCATTATAATTCCATGAAATTAAGATTATAGGTGGAGGTAACGAAT
Associated Phenotype:
Not determined