Busch Lab

ZMP

tmem67

Ensembl ID:
ENSDARG00000076752
ZFIN ID:
ZDB-GENE-080716-1
Human Orthologue:
TMEM67
Human Description:
transmembrane protein 67 [Source:HGNC Symbol;Acc:28396]
Mouse Orthologue:
Tmem67
Mouse Description:
transmembrane protein 67 Gene [Source:MGI Symbol;Acc:MGI:1923928]

Alleles

There are 7 alleles of this gene:

Allele Name Consequence Status Availability
sa42734 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa14889 Nonsense Available for shipment Available now
sa32094 Nonsense Available for shipment Available now
sa22858 Nonsense Available for shipment Available now
sa14183 Nonsense Available for shipment Available now
sa22859 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa42734
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111245 Essential Splice Site 321 991 10 29
ENSDART00000140460 Essential Splice Site 314 982 9 28

The following transcripts of ENSDARG00000076752 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 16 (position 29798008)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 27635146
GRCz11 16 27569769
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCAGAATGAACCCCTTCCTGTTGGATTCAGCTTTAAAGGGGCACAAAAGG[T/G]AAACACTGGACATTTAAACGTAAACATCAATGTAGTATTTTTTCACCAAT
Long Flanking Sequence:
TTCCTATTGACTATACTTCATCCTAAGAGTAAAATCTTCTTCATTCTGCACTTAAAATGTCCAGATAACTGATAATCTTTGGATTTGATAATCTTTTTTTCTTTCAATCCTATCAACTATTTTAAAAGAGATTTAAACCTGGAGACTGAACTTTAAAAAAACATATTACAGCAATCCTTGATTCTTTAAGGTGATTGTTTGTCTGGATAGTAAAATGATCATTAACCATAGGCATGGCAATTTTTGCCAATGTGGTCTGATTTAAATCCTTGTTGTTCGTACATTTTTCTACTTTCTGCATCCCTATATTCCCTAAATTCTACTTTTGCCCCATTGGTCCATAAAACATGGCAAATTAACCTGCTTTGCTTGACAATGTTGTTATTCTAGGAGGACAAACCTACCTTGGCTGTACTATGGAGATCAACCAGGGATGGCATCACAGGCTCTTCAGAATGAACCCCTTCCTGTTGGATTCAGCTTTAAAGGGGCACAAAAGG[T/G]AAACACTGGACATTTAAACGTAAACATCAATGTAGTATTTTTTCACCAATCGTTCTGCTGCTTTCAGAACACCAACATTGAGTTGCGAGCTGCTGTGTACTCAGTGCGTGGAGAGTTTCTGAGATGGGAAAGCGTTGGTAGAGGCAACCTTCAGGTAGGCAAGCAGGACTGGTTTCTCTTCTGGGGTAAAATCCATGAAACATTCTGAACTGCTGTTTTCTTGATAAGATTATTAAATGATATATACATTTACAATGTTTGTTGTTAATTTTAAGGTGAATAATTAATTTGTGCATGTAAATCCACAAAAAACTGGTTGTTTTGGTCGTCTTTAATGAAAGTCTTGATCATTTTTTTTCTGCTTTTGGAGTGACAGTCCAACCTGAGGGCTTCCATAGCAACCGCATATTAATACTCTTTCTTACGATTAGCTTGCTATGAGGTAGTGATATGCAACATGAAAGAAAGTACATCAACATACTGAAATAAGTCTCAGATAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14889
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111245 Nonsense 328 991 11 29
ENSDART00000140460 Nonsense 321 982 10 28

The following transcripts of ENSDARG00000076752 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 16 (position 29798094)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 27635232
GRCz11 16 27569855
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TATTTWTTCACCAAYCGTTCTGCTGCTTTCAGAACACCAACATTGAGTTG[C/T]GAGCTGCTGTGTACTCAGTGCGTGGRGARTTTCTGAGATGGGAAAGYGTT
Long Flanking Sequence:
GATAATCTTTTTTTCTTTCAATCCTATCAACTATTTTAAAAGAGATTTAAACCTGGAGACTGAACTTTAAAAAAACATATTACAGCAATCCTTGATTCTTTAAGGTGATTGTTTGTCTGGATAGTAAAATGATCATTAACCATAGGCATGGCAATTTTTGCCAATGTGGTCTGATTTAAATCCTTGTTGTTCGTACATTTTTCTACTTTCTGCATCCCTATATTCCCTAAATTCTACTTTTGCCCCATTGGTCCATAAAACATGGCAAATTAACCTGCTTTGCTTGACAATGTTGTTATTCTAGGAGGACAAACCTACCTTGGCTGTACTATGGAGATCAACCAGGGATGGCATCACAGGCTCTTCAGAATGAACCCCTTCCTGTTGGATTCAGCTTTAAAGGGGCACAAAAGGTAAACACTGGACATTTAAACGTAAACATCAATGTAGTATTTTTTCACCAATCGTTCTGCTGCTTTCAGAACACCAACATTGAGTTG[C/T]GAGCTGCTGTGTACTCAGTGCGTGGAGAGTTTCTGAGATGGGAAAGCGTTGGTAGAGGCAACCTTCAGGTAGGCAAGCAGGACTGGTTTCTCTTCTGGGGTAAAATCCATGAAACATTCTGAACTGCTGTTTTCTTGATAAGATTATTAAATGATATATACATTTACAATGTTTGTTGTTAATTTTAAGGTGAATAATTAATTTGTGCATGTAAATCCACAAAAAACTGGTTGTTTTGGTCGTCTTTAATGAAAGTCTTGATCATTTTTTTTCTGCTTTTGGAGTGACAGTCCAACCTGAGGGCTTCCATAGCAACCGCATATTAATACTCTTTCTTACGATTAGCTTGCTATGAGGTAGTGATATGCAACATGAAAGAAAGTACATCAACATACTGAAATAAGTCTCAGATAGTTCTGATACTTTCCAATATGTTACTTTATACAAGTTTCATGTCTCACCAGAATGTTTCATTGATGTTTTAGCTTAAAATACATAAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32094
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111245 Nonsense 352 991 12 29
ENSDART00000140460 Nonsense 345 982 11 28

The following transcripts of ENSDARG00000076752 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 16 (position 29798889)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 27636027
GRCz11 16 27570650
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCTTGTGTTTTAAAGTCTTGTCTTTAATTTATGTATCTTCTAAAGCTCTG[T/A]CCAGACACCCCTACCAGACAACAGTCTGCCTTCAAATTCGGGACAGCCTA
Long Flanking Sequence:
ACCTGAGGGCTTCCATAGCAACCGCATATTAATACTCTTTCTTACGATTAGCTTGCTATGAGGTAGTGATATGCAACATGAAAGAAAGTACATCAACATACTGAAATAAGTCTCAGATAGTTCTGATACTTTCCAATATGTTACTTTATACAAGTTTCATGTCTCACCAGAATGTTTCATTGATGTTTTAGCTTAAAATACATAATGTATAAAGAATTAATATCATTTAACATACTAATCTGATAAAAATATCAAAAACCGACATCAAGCTTATTTTTAAGTTTCTATGTGTCTCTTTAAATGCAAATTAGCTGCTGCTCTTTCCAGAAAGTGAAGCATTTTCAACCCATCTCTTGATCCTCTCACAACAAAATGTCTAAATGTCTGTTGCAATATCAAATGTGCTTATGTGACATTGAAGCTCTTCAATCAGAAGAAAGTTTATTATTTGCTTGTGTTTTAAAGTCTTGTCTTTAATTTATGTATCTTCTAAAGCTCTG[T/A]CCAGACACCCCTACCAGACAACAGTCTGCCTTCAAATTCGGGACAGCCTACAAGCAGAGTGTAAGTCTCATTTATCTTCTGCCTCAACCAGATGGTATTTAGCTATTTGTTTTGTATGTAAATATGTAAATGTGTATTTAATGGCATTTTTCTTTCCACAGTGTGTGCTATCTGTGTCAGAGCTCTTAACTGGTTATCCAGAGCCTTTGTTCTATGATGTGTTCCTGGTCATTCAGAATTCCCAAGACAATCGTCTTCTTGCGGTGCCTCTCCTAAATGCCAATCAGCAGTTTAACGGCCAGTTTGTCAATCAGGGTATAATATCCAATTATATATTTGATCATCAGATGTTAAGGCATTGCTATTTTATTATAGTGTTAACTCCTCATTTATTAGGATCTGACATGAGTAAATGGTTCCTGACCCGAAGGCTGATGCTTGTCGACACATTGAGTGGAAGAGAGAAGTCTATAAGTTCTTCACCCGTAGTTATACGAGTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22858
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111245 Nonsense 390 991 13 29
ENSDART00000140460 Nonsense 383 982 12 28

The following transcripts of ENSDARG00000076752 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 16 (position 29799104)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 27636242
GRCz11 16 27570865
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTGCTATCTGTGTCAGAGCTCTTAACTGGTTATCCAGAGCCTTTGTTCTA[T/A]GATGTGTTCCTGGTCATTCAGAATTCCCAAGACAATCGTCTTCTTGCGGT
Long Flanking Sequence:
ATTAATATCATTTAACATACTAATCTGATAAAAATATCAAAAACCGACATCAAGCTTATTTTTAAGTTTCTATGTGTCTCTTTAAATGCAAATTAGCTGCTGCTCTTTCCAGAAAGTGAAGCATTTTCAACCCATCTCTTGATCCTCTCACAACAAAATGTCTAAATGTCTGTTGCAATATCAAATGTGCTTATGTGACATTGAAGCTCTTCAATCAGAAGAAAGTTTATTATTTGCTTGTGTTTTAAAGTCTTGTCTTTAATTTATGTATCTTCTAAAGCTCTGTCCAGACACCCCTACCAGACAACAGTCTGCCTTCAAATTCGGGACAGCCTACAAGCAGAGTGTAAGTCTCATTTATCTTCTGCCTCAACCAGATGGTATTTAGCTATTTGTTTTGTATGTAAATATGTAAATGTGTATTTAATGGCATTTTTCTTTCCACAGTGTGTGCTATCTGTGTCAGAGCTCTTAACTGGTTATCCAGAGCCTTTGTTCTA[T/A]GATGTGTTCCTGGTCATTCAGAATTCCCAAGACAATCGTCTTCTTGCGGTGCCTCTCCTAAATGCCAATCAGCAGTTTAACGGCCAGTTTGTCAATCAGGGTATAATATCCAATTATATATTTGATCATCAGATGTTAAGGCATTGCTATTTTATTATAGTGTTAACTCCTCATTTATTAGGATCTGACATGAGTAAATGGTTCCTGACCCGAAGGCTGATGCTTGTCGACACATTGAGTGGAAGAGAGAAGTCTATAAGTTCTTCACCCGTAGTTATACGAGTGGCTTCTGACATTAAGATCGGGTAGGAATTACACACTGCAAACACATTAAATAGATATAGTATTGAGTATGACTTCATTGCACAGTGTTTCATTGAACAGGTTTCAGCTGGTACCAAATACACAGAAGGGACAGGTTTACCCTCCACTGATGAGTGTGGCCTACTCGGATATACAGATCAAAGACCCCAGCACACAGACTGTTACTGTAAGTCCAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14183
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111245 Nonsense 486 991 15 29
ENSDART00000140460 Nonsense 479 982 14 28

The following transcripts of ENSDARG00000076752 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 16 (position 29799552)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 27636690
GRCz11 16 27571313
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CCAAATACACAGAAGGGACAGGTTTACCCTCCACTGATGAGTGTGGCCTA[C/A]TCGGATATACAGATCAAAGACCCCAGCACACAGACTGTTACTGTAAGTCC
Long Flanking Sequence:
GTGTGCTATCTGTGTCAGAGCTCTTAACTGGTTATCCAGAGCCTTTGTTCTATGATGTGTTCCTGGTCATTCAGAATTCCCAAGACAATCGTCTTCTTGCGGTGCCTCTCCTAAATGCCAATCAGCAGTTTAACGGCCAGTTTGTCAATCAGGGTATAATATCCAATTATATATTTGATCATCAGATGTTAAGGCATTGCTATTTTATTATAGTGTTAACTCCTCATTTATTAGGATCTGACATGAGTAAATGGTTCCTGACCCGAAGGCTGATGCTTGTCGACACATTGAGTGGAAGAGAGAAGTCTATAAGTTCTTCACCCGTAGTTATACGAGTGGCTTCTGACATTAAGATCGGGTAGGAATTACACACTGCAAACACATTAAATAGATATAGTATTGAGTATGACTTCATTGCACAGTGTTTCATTGAACAGGTTTCAGCTGGTACCAAATACACAGAAGGGACAGGTTTACCCTCCACTGATGAGTGTGGCCTA[C/A]TCGGATATACAGATCAAAGACCCCAGCACACAGACTGTTACTGTAAGTCCACAATGGTTTCTCTGATTGGCATGCAAAACAACCAATCACGGTTTGTTTATGTGCGTAAATGTCAACATCCCTACAGTAACAGACAGACGGGATTGTTTTTGTTTATGCCAAGTGCTTAAGGAAAACTTTTGCACATATTCTAAAGAGTTTATGACTTCTAGTTGATTATTTGGTAAAGTGACAGTTATTTAAGATGAATCATCTGTTGAACTGCATCACAATCATAACAAATACTGTAGAAGACCTATTGGAACCCACATGGACCAAAAAATCTCACAGAAATCAGTTAAGCTGGTTGAAGAAAAAAATCATGGTTTGGGGTTACAGTCAGTATAGGAGTGTGCGAGAGATCTGCAGAGTGAGTGGCAACATCAATAACCTGGGGTATCAAGACATTTGTGCTGCCCATTAAATTACAAACCACAGGAGAGAGCGAATTCTTCAGCAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa22859
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111245 Nonsense 779 991 24 29
ENSDART00000140460 Nonsense 770 982 23 28

The following transcripts of ENSDARG00000076752 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 16 (position 29806766)
Other Location(s):
Assembly Chromosome Position
GRCz10 16 27643904
GRCz11 16 27578527
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTTATTTATATGTGTGTGTCATTTAGATCTCAGTTCTGCTGCTGTCTCAT[C/T]GATGTTTTGGCTACTACATTCATGGGCGCTCTGTTCATGGTCATGCTGAT
Long Flanking Sequence:
TATTAAAGGGAACCTATACAATTGTTAGTTTAATTAACAGTACATATTGTTTTTTTTTTCAGGTTGTAGGCTTCTCAAATTTGGCTCTAAGAGATCCTTCGTCTAACCTGAATCGATCTGCTGAGGAATACACGCCTCCATACAGCCTCATACTCCGCTATGGTGTAGCTACTGCTATGTGGCTCTGCATTGGCTTAATACAGGTACATACGAAAATAGACAAGAGGCATACTAATTGTGTCACCAATTAGATTCCACATGCTCTTCTTTGTGTGATTGTGCTTCAGATGATATTCTTCACAGTGTTCCATGAACGGTTTGTTGAAGACAAGATTCGTCAGTTTGTGGATTTGTGCTCAATCAGTAATGTAAGTATCCGGCTGGAAATCTTGATGATAAATGTAGTTATAAACCACATCTTACATCATGGTTTAATGTTGTTTGTGTTTCTTTATTTATATGTGTGTGTCATTTAGATCTCAGTTCTGCTGCTGTCTCAT[C/T]GATGTTTTGGCTACTACATTCATGGGCGCTCTGTTCATGGTCATGCTGATACTAACATGGATGAGATGAACACTAACCTTAAGAGGGAGGCGGTAAGATTTTGAGGCTTACTGTTTATAGTAGTTTTGAAATAAATAAGTTATTTATTGTATTTTTTATGTGTTTTAGGAGAATCTGTGTGGCCAAAGGGGACTTTTGCCAAACTCTGATACTCAGACGTTTCAGATTTCGATAACTAACCGTCTGCGAGCACAGTATGATCGGATAATCGAGCCAATCAGCAGGGTATAAACACAAGCAAATACTATGTCAAATATTTCCCCCAAAATTAGACATGCCTGTTGAAATTGCCTTTAAAAAAAGAAAAGATGATCAGTCACATTGGTGCTTAAAGAAACACTTTCTTTCTTTCTAAAGAAACAGTTTCACTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTCTTTTTATAAAATACTCATTTTACATGAGCCTAGTGT
Associated Phenotype:
Not determined