Busch Lab

ZMP

pi4kaa

Ensembl ID:
ENSDARG00000076724
ZFIN ID:
ZDB-GENE-100204-2
Description:
phosphatidylinositol 4-kinase alpha [Source:RefSeq peptide;Acc:NP_001030144]
Human Orthologue:
PI4KA
Human Description:
phosphatidylinositol 4-kinase, catalytic, alpha [Source:HGNC Symbol;Acc:8983]
Mouse Orthologue:
Pi4ka
Mouse Description:
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide Gene [Source:MGI Symbol;Acc:MGI:2448506]

Alleles

There are 9 alleles of this gene:

Allele Name Consequence Status Availability
sa8479 Nonsense Mutation detected in F1 DNA Not yet available
sa8903 Nonsense Mutation detected in F1 DNA Not yet available
sa41573 Nonsense Mutation detected in F1 DNA Not yet available
sa44718 Nonsense Mutation detected in F1 DNA Not yet available
sa2547 Nonsense F2 line generated Not yet available
sa2563 Essential Splice Site F2 line generated Not yet available
sa34812 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa8479
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113162 Nonsense 40 2097 2 55
Genomic Location (Zv9):
Chromosome 10 (position 3265570)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3257764
GRCz11 10 3258068
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTWAWATGCACATTTGTTAAATATAGGTCCAGAAGCTACAATGCATGTG[T/A]CCTGTGGACATCCGTGGTGTTTTCCAGCTGGACGAGCGGAGGAGAGATGC
Long Flanking Sequence:
TTGTGGAACCCAGCTTTTTTTTTACAGTGAAGCGTGATGTATTTTTATCTTTAGTTTTTAATTGTATTTAGTTTTTTTAATATTTAATTTAAATATTACTGTTTAATATGCATTTTTATGTGACATGCTGTGAATATTTGCTGTCTTTATGGCCATTTTTGGCCACATTATATTGTTTTACTGAAGACGTAATGATTCTCTTTTAAATAAATATGTTAATTTGTTTTGATTGAGTAATTTCAGTGCTTTCTATTTGAAGTATAGCTTCCAAAGAAACATTTCCAATTGTCCAAAAGCATTTTAATGATTTTAGCTAATAAATAAATGATTGTAGTGGTGTGATCTTTTTTTTTTGGTTCACAAAATATATGATGAAATATTTTTACAGATTATAATACTGACACAAAAAGAAATCTCCCTGCTTCGGCAATAAAAAGTATTTCACAATTTTTTAAAATGCACATTTGTTAAATATAGGTCCAGAAGCTACAATGCATGTG[T/A]CCTGTGGACATCCGTGGTGTTTTCCAGCTGGACGAGCGGAGGAGAGATGCTGTGATCGCACTTGGGATCTTCCTAGTGGAGTCTGAGTTGCAGGTATTGGTTTAACATAGTCAAACTATATGTTTCATTGATTAAAATCAGGACTAATGAGGCACATTTAAAGCACTTTAAAAACACTTTTTTCCCCAAAATATAATAAAGGGATAGTTAACTCAAAAAAGTTCCTCACTCTTTACTAACCAGGGTGTCCGCGGGGCTTTAAAAAGTATTAAAAGTTGATAAATCAAAAAGCTATAACCCGGAAATGGTATAAAGAAGAGCCACCAACTAAAGATAAATGGTTTAAAGTTATAGCAGAAGTTGAGGAAATGTAAAAAATGACACATGCACTTTGATTACAGGGCTCGAAATTAACTTTTTTACTTGGTAGCACCGGTGCTCCCAACTTCAAATATTTAGGAGCAACAAAAAAATTTTAGGAGCACCAGAAAAAATTTAGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa8903
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113162 Nonsense 405 2097 11 55
Genomic Location (Zv9):
Chromosome 10 (position 3254886)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3247080
GRCz11 10 3247384
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTCAGCAGCAGTCAGTCTGAGCTGCARAGGATCCTGCACGATGTGGAGTA[T/A]CTGCACAGTGAACTGAACCCGCTTAAGCTGCGCTGTCAGGCCAACGCCGC
Long Flanking Sequence:
TTCAGCCTTCTCAATTATATTAACGCATATTTTTTTGTCAGTAATGGAGAGGGCGTTGTAACAGGGAAACAGTAATTCGTTAATAAAGATGAAGGAAAGACTAGTGGTTGCTGTTTGGAGTTTTCCAGCGCTGTATAACTTCACAAATCTTGAATATCACAATTTTATTATAATGTTAAAAAGCAGCAGGCCTGGAAGTAAGTCAGTCTTTTTCTTGTCAACAAAAAGGCAGTGTGCTGTGCCTTGCATTCATAGAATGGAAAAGGGTGCACAGTGTGATCGGCCACTAAGAAAGTGTTGTATTTAAATAAAAGTGTTTTATTTACATTAACCAAATCAGTCACGCTTTTTCTACAGATGTTTTATCACATTTTTTGCGCATTTTTTTTTGTGTGTGCAGATCTGCAGGTGTCGTTTGTGAAGGAGGTCCATGACTTTGTTCTGGAGCAGTTCAGCAGCAGTCAGTCTGAGCTGCAGAGGATCCTGCACGATGTGGAGTA[T/A]CTGCACAGTGAACTGAACCCGCTTAAGCTGCGCTGTCAGGCCAACGCCGCCTGTGTGGACCTCATGGTGTGGGCCGTCACGGAAGAACAGGGTAAGACTTGACAGAGAAATACACCACAACACTTATGTCTTGTGAACAGCGGTGTAAAGTAACATTACAAATACTCAAATTTCTGTAATTGAGAAGTTTTTCACCAGTTTTTAAGTGGTTTTAAAAATGTGTACTTTTGCTTTCCCTTCAGTACAGTTTTAGTGCAGTATCGGCACTTTTACTCCACTGTTTTTTATTAATCTGCAGCCACTTTTTTATTGTCGAAAAATCGAAAGATCACTCCTGCGATTCCAGTCCAATCAAATAATAATAATTTTCAACCGTAATGAACAATTTCGAGGCATGTTTGGAAGGTGTCCTATAGAGTTTAGTTTCTCTGTCTGAGCCCAAGCCCACATGGGCAGGGCCGTGATCGAGCATTTGTGGGTCATTACTTAGGCCGTACGCT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa41573
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113162 Nonsense 620 2097 16 55
Genomic Location (Zv9):
Chromosome 10 (position 3247174)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3239368
GRCz11 10 3239672
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACATCGCTGTGGCTCTGAGAGACACTCCACGAGTGATGGAGCCCATCTTA[C/T]AGATCCTGCAGCAGAAGTTCTGCCAGCCGCCGTCTCAGCTCGACGTGCTC
Long Flanking Sequence:
GTTAAAAATATCCTGGATTTGAAAATATTGTGTTCCTAGCCTTCACCGATCTCAAGTAATAGATTAATGTATAAAAATTGTGAATAAACTTAACTGTTGATGTCTTAAATAATAATGTCATGTAATAATGTAAATGGATATATCTCGTTTTGCAACGAAACTCTTCATTCATTTTATGAAATATATCAGGATCTAATATTTTTTTGTTAATCTAGGTGTTTAAAAGCAGGATTGACCATGGATTCAGTCATCGTTGAAGCTTTCCTCGCCAGTCTTTCCAACCGTCTGTACATTTCGCAGGAAAATGACAAGTATGTTGCATTTGACAGATGATAGCTTGAATAATTTTACAGCCCTTAAAAGAGATTTGTAAGAATGAACATCATTTGTGCTGTTTTCCTCTCAGGGATGCCCATCTAATCCCGGACCACACCATACGGGCGTTAGGACACATCGCTGTGGCTCTGAGAGACACTCCACGAGTGATGGAGCCCATCTTA[C/T]AGATCCTGCAGCAGAAGTTCTGCCAGCCGCCGTCTCAGCTCGACGTGCTCATCATAGATCAGCTGGGCTGTATGGTCATCACTGGAAACGTATGCCAGCTCCTCTGTGTTCTGAAAATCAGGGTTGTATGTTTGGATCCGTGCTAACATCTCCGCGTTTCTGTCCCACAGCAATATATTTATCAGGAAGTGTGGAACCTGTTCCAGCAGATCAGCGTGAAGGCCAGCTCCATGGTTTACTCCACCAAAGACTACAAGGATCATGGATACAGGTGATTTATTTTTACATGTATTTATTATTTAGTGAAATGTTTTGACCTACAGGTTTTTGCGTCATGCTGATGGATAAATAATAGGGGTGTCACGATTTCGATTTTTAATCGAAATCGATCGAAATTTATGCTCAATTTCGATTATCGAATCAAAAAATAGAATCGTCGATGCTGCCACGCCCCCATGTCACGTCAGCTTGGCTTGCCAAGCAGGAAAAAACAGGCTTGT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44718
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113162 Nonsense 759 2097 20 55
Genomic Location (Zv9):
Chromosome 10 (position 3240141)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3232335
GRCz11 10 3232639
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ATTGGGATATGTTGTTCATAATCTGTCTGTTTTTTACCCTATAGCTAACC[A/T]AACGTTTGCCGGCCATAAAAGAAGCCAAACCGAGGCTGCAGAAGCTGTTC
Long Flanking Sequence:
AATAAAACGAAACATTCATTAATTTTGTAAAAATGTTTATTGCTCATTGTGAGTTAATACATTAGCTAACGTTTCATTTCATTTACAAATAGCAGGGTATTTGCAGCTACTGTCTATTTCTGTCCATTTGTATCGCTCCCTTTGTGCCCCCTGGTGGCATTGTCGCAAACTGCTGTTAGTCCTAAACACATTTCTGTAATGGTCATCCTGAACTGTCACTCATTGTGTGTGTAAAAAGGCATCTGACCTATTTTATTTTTAACTAATATTTACTTTAATGAACATATAAATCGATATACAGTAAATGACGCTTAGAAAAGGGTATACATTTAGCTTTTACTCATTTAAAAAAATAAATTCTTTTTCGAGTCTGTTTTTGCTGCTAAAATGAACATTATTTTACCTCAGTTGCCGACAGTTTACACAATTAATGTTTTTGGTTGAGAGCCGATTGGGATATGTTGTTCATAATCTGTCTGTTTTTTACCCTATAGCTAACC[A/T]AACGTTTGCCGGCCATAAAAGAAGCCAAACCGAGGCTGCAGAAGCTGTTCAGAGATTTCTGGCTGTATTCGGTTGTGATGGGCTTCGCTGTTGAGGGCTCAGGTTAGACATCCATATTAATAAATGTTCACATGTACATCATTTAGTTTAAGATTTTGTAGCATTTTTGTCTGTTTATTTGTTGAATGTTGGACAAAACACAGTACTTTGCAAAAGTTTTAGGCCAACATTAAATCTTTTACTGACGATATAATGGATAAATGTGACTCTTTTTCACCCATAAAAGTCATAAGTGTATATTTTTAGTCAATTTATTTTAAATTGAGATATCTTCAGGGTGAATAAATGATCTTTCAGTTGATGTACGGTTTGTTAGGATAGGAGTTAGGTTAGAGTTTGAATTACTTTGGTTTATATGTTTAAGACATGTGAAAGACAGTGTTGGAGAGAGGCTGTTTGTCCTAGTTTGAGCTGCATTTCTAGCAGTGTTGTTGTTAGCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2547
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113162 Nonsense 1156 2097 31 55
Genomic Location (Zv9):
Chromosome 10 (position 3228369)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3220563
GRCz11 10 3220867
KASP Assay ID:
554-2640.1 (used for ordering genotyping assays)
KASP Sequence:
TCTCYGAGGCCACGCGGAGCACATCAGACCTGAATAAACTGATGATCCGA[C/T]AGATGAATGAAGCTCTGGATGGAGGACAGCCCGAAGCCTTCACCGAAGCC
Long Flanking Sequence:
CGCCATTTTAAAAACTTAAACCACTAGTGTAAACGGGGCCTAAATAGACACTATTTAATCAACATTTTCCCTGTACCCATAATGCCCATTGGTTAATCCGGCCCTGACTGTGGAACTTTGTAGTGTAAATTCATCGCAGTTTGGTTTGGAACAAGTGAATATTCAAAAAATTGAGAATCGATCGGTGCATTTCTACTGAATTGATTTATTGACTAGTCCTTCAGGTTGCAAACAGTCATTAAAAGTTTGTTCCCCATCATTTCAGACCACTCAGCTGACCGAGAGACCCGCATGCGTGAAGAAAGACTACTCCAACTTCATGGCCTCCCTCAACCTGAGAAACCGCTACGCTGGAGAGGTGCTGCTAAATAATGAAGCAGGGCTTTTTGTGTTTGTTTCACCGAGTCTTACCCCCTGTGTCTCGTATGCAGGTCGCAGGGATGATCCATTTCTCCGAGGCCACGCGGAGCACATCAGACCTGAATAAACTGATGATCCGA[C/T]AGATGAATGAAGCTCTGGATGGAGGACAGCCCGAAGCCTTCACCGAAGCCCTGTTCAAGATGGCAGCGCTGTTGATCAGCTCCAGAGGCACGTTTTATTGTGTTTTATAAGCTGTACACTAGCAGATGGTCAAATGTTTTAAAGGGACAGTTCAATCCAAAACTGAATTCAACTTTTAAACTTTATCTTCTGTCCAACACACATAAAGATATTTACACTCACCGGCCACTTTTTTAGGTACACCTGTCTAACTGCTCGTTCACGCAAATTTCTAATCAGCCAATCACACGGCAGCAACTCAATGCATTTAGCCATGTAGACATTGTCAAGACGATCTGCTGCAGTTCAAACTGAGCATCAGAATGGGGAAGAAAGGGGATTTAAGTGACTTTGAACGTGGCATTTTTACTCACAACCATTTCTAGGGTTTACAGAGAATGGTCCGAAATAGAGATAATATCCAGTGAGGAGCAGTTCTGTGGGCGCAAATGCCTTGTTGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2563
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113162 Essential Splice Site 1367 2097 36 55
Genomic Location (Zv9):
Chromosome 10 (position 3217790)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3209984
GRCz11 10 3210288
KASP Assay ID:
554-3190.1 (used for ordering genotyping assays)
KASP Sequence:
GTAATTTTKGCATAATAGCTTTAATTCTAATATATTTTGTTGTTCTCTTT[A/G]GTGTGGCATCAAAGTTCCCCACTYAGGGAGACAAGCGTCTGCGGGAGGAC
Long Flanking Sequence:
TCGGCTGATTATGTCCATTCTTTCAAGATGTACAATAACCTCCCTAGTGTGTGTATATGAAGTTTCAACTCAAAATATCCCACAAAGAATGTTTTATAACTCTTTGAAACTGCCCCTTTTATGCTTTGATCCTAATGGTGCCGTTTTGGTGACTGTCACTTTAAATTCAAATTAGATTGTGCTCTTTTCAAAAGTGGGCGGAGCTACAAATGTCCGTGTCAGTATAATGGAAGATTCAAAATCAAAACTAACCTCCCATGCTAATTAGGGAGAGATGGTCACAAGTGGGCGGGGCTTTCCCTCTCTGATGACACATACAAAGGGAAAATGTCAATCAAAGTGTTTTTATCAAATGTGATTATAAAAATAGAATTAATTTGTTTTTACTATTAGAGGTTGGTTATATTTACAGACTGCTGACCCACACCTGTGATTAAACTCCTTCTAAAAGTAATTTTTGCATAATAGCTTTAATTCTAATATATTTTGTTGTTCTCTTT[A/G]GTGTGGCATCAAAGTTCCCCACTCAGGGAGACAAGCGTCTGCGGGAGGACATCAGCATCATGATCCGCTTCTACGCCAGCATCCTCTCCGACAAGAAGTACCTAGGTGCTAGCCTGCTCGTGCCACCTGGTGAGCTCGGTGCCAATCCCCCTCAAAGCTCCCTATCTGCCGGGATTTTCGGATCGCTTATCGTTTCCAGCACTTCTCCGATATCGATCTTAAGTAAGCCTCTACTTGCTCCGACTGTGCGACTACAGTGCGGCAGGAGCATGTTAATGCGGTTTCAAATTAGCATGACCGCCAATTTGAAACCCATACTACAAAACTGCACGGCAATCATCCGGACGGCCGAATTGATCAATTTGACGCCAAGCGCAAATTGAGAAATGCAACCGTCCCATCTTACCCCACCCCCCTCCCGACCCGTACCGCCACCACCCTTTATTGTAGAAGAACATGATCTCATCGCTTCTCATGTAAAATGCATGATCATTTCAGTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa34812
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000113162 Nonsense 1819 2097 48 55
Genomic Location (Zv9):
Chromosome 10 (position 3203481)
Other Location(s):
Assembly Chromosome Position
GRCz10 10 3195675
GRCz11 10 3195979
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGTATGTGTTCTCCTAAGTGGTCTCTCTGTGTGTGTGCAGGTCTGCGCTG[T/A]CCGTCCGACTCTCAGGATGAAGGAGATGAGAGCTCACTGACGGCTCAAAG
Long Flanking Sequence:
CACGTAGATACAGTAGGCGGGAAAGACTTGAATTAAAGGCGCAGTACGACAAAACCACCCCCTGCTGGAAATGAGTATAAAATATGATCTTGTAAAAGGTATAATGAAAAATCTGGTGGGTGTTTTGAGCTGAAACTTTATATACACATTCTAGAGACGCAAAAGACTTATATTAAATCTGAAAAAAGGGGTAACCTAGGTGCCCTTTAAGCAATATATGTTTTCAGATGTCTACAGAACAAACCATCGTTATAGAATGACTTGCCTATCTACCCTATTGAGTTATTAAAACTATTATGTTTAGAAATGTGTTGAAAAAAATCCTCTCTCCTTTAAACAGAAATTGGGAGAACAATTATACAGGAGGGAGAATAATTCTGATTTGAACAGTATCTAGTATATCAATGACATCCAGGGAATGTGAGAATTGAGGGACTGATGTATTTCAGTTGTATGTGTTCTCCTAAGTGGTCTCTCTGTGTGTGTGCAGGTCTGCGCTG[T/A]CCGTCCGACTCTCAGGATGAAGGAGATGAGAGCTCACTGACGGCTCAAAGGGTCTGCTGGCAGGCGGCCATCTTTAAAGTGGGCGATGATTGCAGACAGGTCAGTCTCATAGGAAACATCCGGTTACCTTTATTCCAAATTCATTCAGTAAATAAAAACTATTATTTAATGTAAATAGGAAAACCATATGAAATCCTCACAATTTTTGTTTTTTATTCCAAGAACCAATTACTGTTTTCTTTTCACAACACATTTTTTGCTATGAAATAGAATAAAATGTCATAATTCTAATGCCAAAAATTATAATAAATATAATGTGCAAAGTGTGCATCGGATGCAAGTTGACATTTACACTCACCGGCCACTTTATTAGGTACACCCATCCAACTGCTTGTTAACACAAATGTCTAATCAGCCAATCACATGGCAGCAACTCAATGCATTTAGGCATGCAGACATGATCAAGATGATCTGCTGCAGTTCAAACTGAGCATCAGAAT
Associated Phenotype:
Not determined