Busch Lab

ZMP

LOC569768

Ensembl ID:
ENSDARG00000076508
Human Orthologue:
GRM8
Human Description:
glutamate receptor, metabotropic 8 [Source:HGNC Symbol;Acc:4600]
Mouse Orthologue:
Grm8
Mouse Description:
glutamate receptor, metabotropic 8 Gene [Source:MGI Symbol;Acc:MGI:1351345]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa24692 Nonsense Available for shipment Available now
sa24693 Nonsense Available for shipment Available now
sa14553 Nonsense Available for shipment Available now
sa45855 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa24692
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112940 Nonsense 23 907 1 10
Genomic Location (Zv9):
Chromosome 25 (position 27789966)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 26480060
GRCz11 25 26923262
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TATGGTATGGCTGTCTTCTTCTTCTAACTGGGGTGACTAGATCCATCAGC[C/T]AGCGTACGGATCCACTGACTCCCCCTGCTCCTGAATATGCCCATTCTATA
Long Flanking Sequence:
TGTTTAGCGAATACACAAGTGCACTGATCATTCTCCATTTTTTTTCACACTTTGAGACTTCCTGCTGTGCAATGCATGCGTGTTCTGATAAATAATGTGCACCAATGTTGCTGATGAAAGCATATTCTTCTGCTGTTCTCTCTCACACAGGGTTCTAATGGTCTGTGACCTCTGTAATTGAGGAGCTAGCAACTATGTGATTTCGCTCATATTCCATCATCTCATTCGAAGCGTCCTTCTTCATTTGTCCCCCAAAACTTCCAGGCAAATCCAATGGTCTCCTTGACGTCGGACTTTGATAGCTGGTATGCAGTTGCTCCACTGAGGGGCACTGATGACCCCCTTCAGTTATTGCGCTCGGTCCCTGCTGGCTTCCCACCTTTGTAACTGCGTCCTCACTGCTGCTTGTACATCTGGATCCACTTCATGTCACCATGTTGAGTGCCTTTGTATGGTATGGCTGTCTTCTTCTTCTAACTGGGGTGACTAGATCCATCAGC[C/T]AGCGTACGGATCCACTGACTCCCCCTGCTCCTGAATATGCCCATTCTATACGACTGGATGGGGACATCATCCTGGGTGGTCTTTTCCCAGTGCATGCTCGGGGCGAACGGGGTGCTCCTTGTGGGGAGCTTAAGAAAGAGAAGGGTATTCATCGGTTAGAGGCTATGCTTTTTGCTATCGACCTCATCAATAAAGACCCTGACCTGCTGCCCAATGTTACCTTGGGGGCGCGCATTTTGGACACCTGTTCACGAGACACTTATGCCCTGGAACAGTCGCTTACTTTTGTGCAGGCCCTCATTGAGCGTGATTCTACTGATGTGCGATGTGCTAGTGGTGAGCAGCCCATCTTTGCCAAACCGGACAAGATCATTGGTGTGATAGGTGCAGCAGCTAGCTCAGTCTCCATAATGGTGGCCAACATTCTACGCCTGTTTAAGGTAATTCTGTCTATGTTTTACTATTGGTGGCTTTGCATCAAGACGTACAGAAGAACCTTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24693
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112940 Nonsense 97 907 1 10
Genomic Location (Zv9):
Chromosome 25 (position 27790189)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 26480283
GRCz11 25 26923485
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCTATCGACCTCATCAATAAAGACCCTGACCTGCTGCCCAATGTTACCT[T/A]GGGGGCGCGCATTTTGGACACCTGTTCACGAGACACTTATGCCCTGGAAC
Long Flanking Sequence:
ATTCGAAGCGTCCTTCTTCATTTGTCCCCCAAAACTTCCAGGCAAATCCAATGGTCTCCTTGACGTCGGACTTTGATAGCTGGTATGCAGTTGCTCCACTGAGGGGCACTGATGACCCCCTTCAGTTATTGCGCTCGGTCCCTGCTGGCTTCCCACCTTTGTAACTGCGTCCTCACTGCTGCTTGTACATCTGGATCCACTTCATGTCACCATGTTGAGTGCCTTTGTATGGTATGGCTGTCTTCTTCTTCTAACTGGGGTGACTAGATCCATCAGCCAGCGTACGGATCCACTGACTCCCCCTGCTCCTGAATATGCCCATTCTATACGACTGGATGGGGACATCATCCTGGGTGGTCTTTTCCCAGTGCATGCTCGGGGCGAACGGGGTGCTCCTTGTGGGGAGCTTAAGAAAGAGAAGGGTATTCATCGGTTAGAGGCTATGCTTTTTGCTATCGACCTCATCAATAAAGACCCTGACCTGCTGCCCAATGTTACCT[T/A]GGGGGCGCGCATTTTGGACACCTGTTCACGAGACACTTATGCCCTGGAACAGTCGCTTACTTTTGTGCAGGCCCTCATTGAGCGTGATTCTACTGATGTGCGATGTGCTAGTGGTGAGCAGCCCATCTTTGCCAAACCGGACAAGATCATTGGTGTGATAGGTGCAGCAGCTAGCTCAGTCTCCATAATGGTGGCCAACATTCTACGCCTGTTTAAGGTAATTCTGTCTATGTTTTACTATTGGTGGCTTTGCATCAAGACGTACAGAAGAACCTTATTTCTTTTGATGGAGTATTAAAGAAGAGTTGAATAAACTTGTATTAGAGAGGTGCAAAATTTAAAGCTATAATAACAAAAGGGAATTCAGGAATGGAATATATGTCAGCACACTGTACTAAAGATTATTTGTGCTTTATACGAAAATAAATCTTTAATTAAAGCATTTTTCTGGAAATAAAGACATGCTTTTAAAGTATGTGATTTACTTAAAAACAACACAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa14553
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112940 Nonsense 216 907 2 10
Genomic Location (Zv9):
Chromosome 25 (position 27877007)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 26567101
GRCz11 25 27010303
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TACCAGGCCCAAGCCATGCTGGACATCGTGACCGCCATGGGGTGGAACTA[T/A]GTTTCCACACTGGCATCTGAAGGGAATTACGGAGAGAGCGGTGTTGAGGC
Long Flanking Sequence:
TTACCTAGCTTGCTTGCTGGCAGGCTTCACCTCGATTCTTTCTACCATAGCACGTACTGATTTGTCTTCGTTATCTGGTCTTGTTTCACCTTTAGCGTCACCTCATGGTGTGTTAGTCATTTGCATCTGTGGCTTTGGGCTAAAGCCAGTTTGGAGGTTGAAAATATATCGCTCCACCTTTGCTTGCTTTAATTGGTTGTGCATTTTGCATTTTGCTTCAGGCAGTAGTAAATGATTAAGTCTTGTAAAAGAGTCTTCTTCTTTTGGGGTTAAAACTTTCATTTTTCCCTATATTTTTAGCTCTGAAGGATCTCTTAAATCTGTACCACTTAACAGTTTGTTCTTTGTTCCTCTTAACAGATCCCTCAGATAAGCTATGCATCCACAGCTCCAGAGCTGAGTGATAACACCAGGTACGACTTCTTCTCCCGGGTTGTACCGCCGGACTCCTACCAGGCCCAAGCCATGCTGGACATCGTGACCGCCATGGGGTGGAACTA[T/A]GTTTCCACACTGGCATCTGAAGGGAATTACGGAGAGAGCGGTGTTGAGGCTTTTGTTCAGATCTCACGAGAAACGGGTAAGTTTCCAGAGAACATTTTGAAATGTGTTTTTTATACCAGGGCTCCAGATTATCTTCTGCTGTATGTCTCGCTTCACTGATCTCAACTGATTGACTGACTGAATTGGATTTCTTTTCACATAGTGCTTTGTGTTCAAGGGATATATTCTAAACAGCTTTCTACTTTATATACAGTATGTATTATATTTTGTTTATATTTAATGTTTTTGTTTCAAATTTTTTTACTCACTATTTACTCACCCTTTATGAGAAAATATATTTTAAGGAAAGCTGAAAACTTTTAACCATTTACTTCACTTGTAATAAAAACAAATGGATTTCAATAGTTACAGGTGTCAAACTTTCTTCAAAATATCTTCTTTGTGTTCAACAGAAGAAATGCAAAGCAGGTTTGGAGCAAGTGGAAGTTAAGTAAATGACA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa45855
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112940 Essential Splice Site 339 907 5 10
Genomic Location (Zv9):
Chromosome 25 (position 27959274)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 26649368
GRCz11 25 27092570
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TTCTTGAAATCTTGCAATTCTACTGTTTTTCATACATTTTACATATTTTT[A/T]GCCTTTGACAGATATTTCAAAAGCCGTTCCTTGTCAAACAACCGACGCAA
Long Flanking Sequence:
AAACTACAAATAATAAAACCAAACCTGAATCTATACATATATAAAATAAATGCGTCCACAACGTAAACATGAAAATGAAACAAAGAAATAGTAGTGAAACAAACTGAAACTAAACTGAAATTTATAGCAAATCTAAAAATAGTATTAAAAAACAAAAAACAAAAATGTTAAAATGCAAATCTGAAATAACTTTGCAGGTTCCTGAGTTAAATCCTCATTATCATGGTTTAAATATAATATGTTTGCTTATCTTTTAGACGTGTCTTGGATGCTGCAAAGCGTAACAACCAAACAGGTCACTTCCTGTGGGTAGGATCAGACAGCTGGGGCTCGAAGATATCTCCTGTCGTCCAGCAGGAAAGCGTGGCAGAAGGTGCAATCACCATCCTTCCAAAAAGGGCATCCATAGAAGGTAAACACCTCAGGTGGACAAATTCTGATTGAATGCCTTTCTTGAAATCTTGCAATTCTACTGTTTTTCATACATTTTACATATTTTT[A/T]GCCTTTGACAGATATTTCAAAAGCCGTTCCTTGTCAAACAACCGACGCAACGTCTGGTTTGCAGAGTTCTGGGAAGAGAACTTTGGATGCAAGTTGGGCATGCACGGCAAGCGACCAGGAAGCCCCAGGAAATGCACTGGTATGAGAATCTTACATTACTGTTTTTTGGGTTGAGTAGAAAGCTCTACTCATTTTTTTGTTGTTTATGATAAATTAGGGAAATCCTAAATATATTTCTGTAATCCTGGGCTAATATCAATGTTATTTGATCAGTGGTTTCATATCTAAACCAACAGCCACTTAATAGCTGTTGTGATCAAATCTTCCTTGTGATAAAATTCTGGCAGTGTGAGAAGATTTCAAATATTTTCCTACAGTGTGAATTTAGCTGTGATGAGCATAAAACCAAGAACCAATAGAAGCGTTGAATCTAATGATGCAATCTATGCAACAACTTCAAACTAGCACAGGGAAATGTAAAAAATGTTTTGAAATGTTTT
Associated Phenotype:
Not determined