ZMP

smg6

Ensembl ID:

ENSDARG00000075957

ZFIN ID:

ZDB-GENE-081107-52

Description:

SMG6 homolog nonsense mediated mRNA decay factor (C. elegans)cds [Source:UniProtKB/TrEMBL;Acc:C5J7W9

Human Orthologue:

SMG6

Human Description:

Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) [Source:HGNC Symbol;Acc:17809]

Mouse Orthologue:

Smg6

Mouse Description:

Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) Gene [Source:MGI Symbol;Acc:MGI:2144

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa41704	Nonsense	Mutation detected in F1 DNA	Not yet available
sa17851	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa41704

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108897	Nonsense	448	1381	8	25
ENSDART00000135950	Nonsense	607	1544	2	19

Genomic Location (Zv9):

Chromosome 10 (position 36634532)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	35666287
GRCz11	10	35610147

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CTGATGACGAAACCGTAGGAAGTCCTCCAGTCCGCCAGGGGGAGTTCTTT[C/T]AAAATCAGCAGGCCGCAGCTATGGCGTACTACAAGTTCCAGAATTCGGAC

Long Flanking Sequence:

GGAGACGCACGGCCCGTACCTTGTCTTCCACTGACTCGCTGGAGGAAAACGAGGTGTGGGAGCGAGAAGGCAGAAGAAGCAGAGCTGCTGAAGAAGCCAAGAGCAGCACTCGGAAGGAAGGAGGGATCTTAAGAGTGTCTTTAGACAAGCGTGAGGAGCAAGCAAGCCGTAAAAGCACTAGAGGTCGTGGAAGAGGCATCCTGGTGCTTCCTGCCCACACCGACCTAACACAGACCCCTGATCCTGCACCTCCACTTGGAGGAATGAGAGGAGGAATGGGCCTGGGCAGAGGAAGAGGCGGCCGTGGAGGAGGGACCAGACGTCTGTGGGACCCAAATAACCCAGATAAGAAACCAGCACTGGTGTCAAGCCAACAATCCCAGCATGCATCTCAACACCAGGCTTTGTATTTACAGCAGGGTGGATGTGGGCCGCTACACTTTCTTGACACTGATGACGAAACCGTAGGAAGTCCTCCAGTCCGCCAGGGGGAGTTCTTT[C/T]AAAATCAGCAGGCCGCAGCTATGGCGTACTACAAGTTCCAGAATTCGGACAATCCCTACTGCTATCCTGTGTCAGCCAATTCCCCAAACACCCCGCCAAGATATCCATACCCGTATCAGATTCCCTACCAAATACCAGGCTCTAATGGGATGTATCCCGCATCTGCTATGACATCTTTTTATGGACCCTACGGACAGGGTGGGCCAGGTTACCCTTCTCCGACGGTATCTGCTTTGACTCCAGAGGAGGCGGAGGTGCAGACCAGAGGAGAGCTGGGGAAGTTTCTTCGGCTGGCTGACAGTCAGGAACTCCAGCTCAGTAACTTGCTGTCGCGTGAACGTCTGAGCCAGGAGGGCCTGGAGAGGATGGCCCAGCTCAGGTTTGCATTCAAAACTGAAATTTGTCATATTACTGTTGCTACTTATAATATTGGCCAGCCTCATGAGGTTTTCCTCTGATTTGTTTCTTTCTCTTTTGGTGTCCTTCCAGGGCTGAGCTCC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa17851

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000108897	Essential Splice Site	956	1381	17	25
ENSDART00000135950	Essential Splice Site	1113	1544	11	19

Genomic Location (Zv9):

Chromosome 10 (position 36626815)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	10	35658577
GRCz11	10	35602437

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

GGTCTCCTTGTCCAGCGCTGTACTGAACTCCTGAAGGAAACACCTACTGG[T/G]GAGAAAACTACACATTTGCTGAAAYGAAAAAATGTATATACATTAATATC

Long Flanking Sequence:

ATAATAATGATCAAATATGTATTTATTGAATGTTTTGAATTTATGACAACTCTTACTTGCTGGTAATTACCACAGAAATTAATTTAGATTATTTGAGTTTGAGCATTGATTGAGAATATTCTCATTTGCATGATGTGTCATGATTGGTCTTCAGGATGGAGAGTTTCCCTGCTGTAGCCAATCGGGTGTTACTGGAGTTTCGCGCCCTCCTCCAGCATAGCCCCTCCCCCCTCGGGAGCACACGCATGCTGCAGATCATCACCATTAACATGTTCACCATCTATAACGCACAGATCAGAGGTAAAAACTTTACCAGTTCCATAGATCCTGTCCAGTTCATTGACAATCTTTCCTGTTTCAATTTGCCATTTTTTTTTATCAGCCAAAGGACAGGGTGAAACTAGGTCTGCATTAGAAGAGCAGGCCATATCTCTGGGTTTAGCTATGTTTGGTCTCCTTGTCCAGCGCTGTACTGAACTCCTGAAGGAAACACCTACTGG[T/G]GAGAAAACTACACATTTGCTGAAATGAAAAAATGTATATACATTAATATCACAAAACACACCAAAAGTTTAATCTGCATGCCAGATAGACATAGTTTTAAAAAAAAAAATCTGTTACACATTTTTTTACACTTTTTTTTCTTAAAGTTAAAGTTGCTTTAACTGTGAGTGTAGCTTGAGTCCACTTAACTTCAGCTACAGTATGTGTTGACATGTGGCTTTAGGATGCATTTTTTCAGAGCAATCATTTGGGCAATGCTAAATACATGTTGGTGTCACGTTGGCACAGTGGGTAGCACAATAATGACATGAAGCTTGAAACCGAGGTGGAGTGTGACCATATAAGAGGGAAGGGCCTCAGAGAAATCCATCTATATATATTTTTTTAATATTATCAACATAAACTGATAAATGACGTGTTATTTACATTAATTAATTTAGCAGAAGCTTTTATACAAAGCAACTTACAAAACAAGATAAAAGAAACACTTCAAATTATCA

Associated Phenotype:

Not determined