ZMP
si:ch1073-179p4.3
Ensembl ID:
ZFIN ID:
Description:
Novel protein similar to vertebrate thioredoxin reductase 2 (TXNRD2) [Source:UniProtKB/TrEMBL;Acc:B8
Human Orthologue:
TXNRD2
Human Description:
thioredoxin reductase 2 [Source:HGNC Symbol;Acc:18155]
Mouse Orthologue:
Txnrd2
Mouse Description:
thioredoxin reductase 2 Gene [Source:MGI Symbol;Acc:MGI:1347023]
Alleles
There are 4 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa20364 | Essential Splice Site | Available for shipment | Available now |
| sa40377 | Essential Splice Site, Splice Site | Mutation detected in F1 DNA | Not yet available |
| sa8420 | Essential Splice Site | Mutation detected in F1 DNA | Not yet available |
Mutation Details
Allele Name:
sa20364
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000110987 | Essential Splice Site | 130 | 503 | 5 | 17 |
| ENSDART00000133455 | Essential Splice Site | 143 | 309 | 5 | 11 |
Genomic Location (Zv9):
Chromosome 5 (position 17117591)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 14846245 |
| GRCz11 | 5 | 15346462 |
KASP Assay ID:
2259-5546.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
ACCATGTTAGGTCTCTAAACTGGGGTCACAGAGTTCAACTACAAGACAAG[T/C]AAGTTTAACCATTAAAACAACATGAACATGAATCTTTTATGGTTTACAGT
Long Flanking Sequence:
TTATTCACTACCGTTTTGTAAATAAAACGTACTTTATTGCAATTTGGTAGTCGTGATATACTCTTCCTCATTCATTGATATTATCTGTTTTCTTGTGCGTTTTATTTTAAAAGTAATGTTACTTTCCTCCCCCTTGACTCTCTACCTTTGAGATTGTAACAAAGGTGTTTATCTACAGTACATATCTGACGATGATGAATTTTGTTCTGATCTTTAATATGCTGTCAAATATAATAATTTAAATGGAATATAATAATTAATTTCCCTTAAACTTGATGTGTTTTTTACTATTTTTTTCATTATCTAAATAGAACATGTATTCTAATCAATTTCAGTCCTGCACCAGATTGTGCACTTTGTGCACAACATCTGCTAAATGACTGAATTTAAATGTAAATTTTAGCTTTTTATATTTGTTTTGCAGGCCAACAATGGCTGAGGCTGTCCAGAACCATGTTAGGTCTCTAAACTGGGGTCACAGAGTTCAACTACAAGACAAG[T/C]AAGTTTAACCATTAAAACAACATGAACATGAATCTTTTATGGTTTACAGTATATTTTTTAGATAAAGAGTAAATTGTCCCACTTTATATTAAGTGCCCTTAACTAATATGTACTTGCACTGCAATTCATTTCAATGTGCTTATTGAGTTATAACATGTGTTTATATTGTATTTATGTTTGATTACATACCTGCATGTAATTACGCCTTTTATTAATTTCTGCAAGTACATTTAAATTACACTGTTGACAATCCATTACACCCTACCCACACCACCAAACCATTTAACCCTACCTGTATCCCAACTTAATAGTACAAGAAGTGATCTGCAATAAGTTATGAACATGTAAAGTTTAATATATTCATTTAATTTATATTTTGACGCTAGCTTGATTCAAGTACATAGTAGTTAAGGGCACTCAATAAAAAGTGGGGCAGAGTAAACAGTGGGACATTTTGGGATGTTTCCTGTGCAAATATCTCAATTAATCCATATAATGTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa40377
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site, Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000110987 | Essential Splice Site | 178 | 503 | 7 | 17 |
| ENSDART00000133455 | Splice Site | None | 309 | None | 11 |
Genomic Location (Zv9):
Chromosome 5 (position 17115797)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 14844451 |
| GRCz11 | 5 | 15344668 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAACATTCTGTTAGCTACTGGTGGACGGCCAAAGTACCCTACACATGTAA[G/A]TGTGTGTGTGTGTGCGTGCGTGTGCGCGAGCACCAGTGCAGGCGGGCATC
Long Flanking Sequence:
TATTTATTGCTTATGCAGTTTTTATTGGTATAAACCTTTTTTATGGAAAAGTTTTGTTTATAAACCTTCAAACTTCGATCATATTTTGCCTTGAAATAACCTCTGAATTGATAAATTCTCTGTGTTTTATTGATGCTTTTGATTTTTCTTATATCTCCATGTGCAGAAATCTACTTTTTGTAAAACTGGTCATGGGCAATTATACAACCAGTTGGTAGATTTATTCATGTGTTGGTATCTCTCTGTCTAATATAACAGGAAGGTGAAATATTTAAATATGAAGGGCACTCTGCTGGATAAACACACTGTCAGAGCTGTAAATGCCCAAGGGAAGGAGGTACGATTTTAAATATACGGCAGCTTAATTTTTTTAAAAGGTGTTTTACCACCTACTGTATATGAATTGTTGTTTTCCTGTTTATCCTGTTTATAGATGACAGTGACCGCCAGAAACATTCTGTTAGCTACTGGTGGACGGCCAAAGTACCCTACACATGTAA[G/A]TGTGTGTGTGTGTGCGTGCGTGTGCGCGAGCACCAGTGCAGGCGGGCATCAGTGGGTGTTGTTTTTCCACTATGTGACCTTTTTCTGCTGATATTGTGTGTAGGAAAGATAATTTCCTCTTGTCTGACTTGGCCAATGTGATGCAGTTGATATTGTTCTTCCTCAGAATTGAAAGTCTGTTATTTGTCTTTGCTTTCATATCAGTTTAGGATAAAATATGTGAAGTATTACAAGATCAAAAGACAATAAAGCCTGGACCTAACATTTATATTTTTCAGATTTTGGTTAATGTGTTCAATCTATCAAAAATGAATATATTAATTAATTAATTGATTCATTTCCTTTTCGGCTTAGTCCTCTTATTCATCACCACATTGGAGTGAACCGTCAACTTATCCAGTATATGTTTTACACAGTTGATGCCTTTCCAGCTGCAACCCATCACTGGGAAACACCCATACACTCTTTTTCACACACATACACTACGGCCAATTTAGCTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa8420
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000110987 | Essential Splice Site | 463 | 503 | None | 17 |
| ENSDART00000133455 | None | None | 309 | None | 11 |
The following genes are also affected by this mutation:
Genomic Location (Zv9):
Chromosome 5 (position 17015823)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 5 | 14811691 |
| GRCz11 | 5 | 15311908 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTGGGCCGAACGCTGGTGAAGTCACACAGGGCTTTGCTTTGGGCTTCCAG[T/C]ACGTTCCRCACRTCTCTGTAAACTTGCACATGATGMTGGGCTGGAATCAG
Long Flanking Sequence:
CTAATATTCAGTTTAAAGTGTGATTCAAAGGCTTAACTAGGTTATCTAGGCAAGTTAGTGTAATTGGGCAAGTTATTGTTTAAGTGGTTTGTTCTTTTGACAATCGAAAAAAATGTTGCTAAAAAGAGCTAATAATACTGACCATACATTTTTTTTTAAGAAATTAAAAACATAAAATAAAACAAATAAGACTTTCTCCAGAAAAAAAATAAATAAATAAATAAAATTAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATAATTTGGGAAATATTTAAAAAAGAAAAAACAATTCAAAAAAGGCCTAATAATTGCAACTTCAACTGTGTATATGCTCTTTTTCGCAGGTGGTTTGTCTACGAGAAGGTGACCAGCGCGTGCTGGGTCTGCATTTTACTGGGCCGAACGCTGGTGAAGTCACACAGGGCTTTGCTTTGGGCTTCCAG[T/C]ACGTTCCGCACATCTCTGTAAACTTGCACATGATGATGGGCTGGAATCAGATTACATTGATTTGATTTGATGTGTTCTGATGTCCCCCAGGTGTCTGTTTCATTACATGCACATTTGCATGTGAATTCAAATCAGCATTTGTATGGACAGCTGCGGATGAATGAATACAGACTCTGTGTGTTTCTGTCTGCAGGTGTGGACTTACATACGAACACCTCAGGAACACAGTGGGGATTCACCCCACCTGTGCTGAGGAGCTCACCAAACTCAACATCACCAAACGCTCGGGTCTTGACGCCACGGTGACAGGCTGCTGAGGTTAAGCATCCCCTTTCCTGATACTGCAAGCACACGGGAGCCTGTTCGGAGGGTTGGGATAATGTAAGTTCTGGAGGAAGCATCTCATGAAAACACAGCAGGTTTTGGCATTTGGTTAAATGTAAAAATTGAAGTTTTGTCCAAATTTACCCACTCTAAACTCCTTCCAAATATTCCAAAAA
Associated Phenotype:
Not determined