ZMP

LOC797480

Ensembl ID:

ENSDARG00000075867

Human Orthologue:

MKL1

Human Description:

megakaryoblastic leukemia (translocation) 1 [Source:HGNC Symbol;Acc:14334]

Mouse Orthologue:

Mkl1

Mouse Description:

MKL (megakaryoblastic leukemia)/myocardin-like 1 Gene [Source:MGI Symbol;Acc:MGI:2384495]

Alleles

There are 5 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa20004	Essential Splice Site	Available for shipment	Available now
sa10921	Nonsense	Available for shipment	Available now

Mutation Details

Allele Name:

sa20004

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

T > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111769	Essential Splice Site	120	1030	4	16

Genomic Location (Zv9):

Chromosome 3 (position 25032213)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	24610424
GRCz11	3	24740972

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CGCAGTCGTCCAGAGAGGTCAGAGCTGGTCAGGATGCACATTCTCGAAGG[T/C]GAGTGTTTTCATTACTCCCCCTACAGTTCAAACACGCACACACACCCCTC

Long Flanking Sequence:

CAAGACCTTTAACAAGCGTCTTTTTTTTTTTTTTTTTTGCTTTTTACAAAAATAACATTTTCACCTATCCAAAAAGAAGAAGCTATGAGATATATTTGCACCGCACTGACGCAGAGTGTTGCCTGTGATCTGCACAACGCACACAACAAGTTTCTATTTTAGATTTTGTTTTCTCTCCAATGCTTTCTATTTTCCACAGCCCTCAACTTTACCCAGTTATATTTATAATAACCTGAATGTAAGAGTCATTTCTCTTTGTGTCTTTTTTACCTTCCAGCACTGAAAAGTTCAGCGTCTTTTCATGAGCAGAGACGAAGTTTAGAACGAGCACGAGTAAGTTTTCCTATATTTATCAGTCTTCTCAGTGAAGTGTAAATATATATAGCTGTCTTGCTTTACATCTTCTGCTTTCTTGTGTTTCAGACTGAGGACTACCTAAAGAGAAAGATCCGCAGTCGTCCAGAGAGGTCAGAGCTGGTCAGGATGCACATTCTCGAAGG[T/C]GAGTGTTTTCATTACTCCCCCTACAGTTCAAACACGCACACACACCCCTCATTGTTTAGATGTTACACACAGTGTTATGCTCATTTGTCAATTTGAAAAATGTACTTCAAAACTATACTAATTCTAACTAAAAAAATGCAAAAGCATTCAAAATATACTTTTAAGTCTATATTTTGTCCAATGTTATCAGTTTGGGTTTGTAGATTTTAGGTTTTATACATATTCTTAAGTGTCGTTTTTTTCTAAATGCACTTTACTACAATTGCTATGGTTAAACAAGGGTTAGATTTGCAAAACCACAGTTAATTTGTAGTTGTAATGGTTGACTTTAGTATTGTTTTATTGTTTATATTGATATCTATATTTTGAATGTTTTTTTATAGAGGGATGTGTTCATACTTTTTTTTTAACCAATTATTTTATTCTACCATTTCTTTTGTTTACAGTTTTGTTTTAGCCGATTGCCAAATTTTCTGAATGACATGGGGATGCATATAGAT

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa10921

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111769	Nonsense	288	1030	8	16

Genomic Location (Zv9):

Chromosome 3 (position 25040122)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	3	24618333
GRCz11	3	24748881

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

CGCTCTAAGAAAGTGAGAGACAATAAACCTAAAGTCAAGAAKCTGAAAKA[T/A]CACCAGTATGTTCCTCCGGATCAGAAAGCKGAGCGTGAGCCYCCGCCTCT

Long Flanking Sequence:

GAATATTCATATTCAATTTAAATAAATATTTTCTAAAGGCAGCTATACAAAATTATATTTTTGCATATTCAGGGAGCAATAATAAATAGGGGAAAGATAATAAAAAAGGATTTTTTTAAAAGGAGCAAAATTGAAGAGAAACAAAAATAAAAAATAAAATTGTCAATTTTTTGCATAAATTTAAATGTGTTATTTTCTATTTCTAAAGATTTTCAGTGAGAATTTTTTTTTTTTAATAATTATGTATGTTTAAGAAATCTGTTTTATGCAAATTCAACAAAATATATTACCTATATTCACTGAGAAATGGATACAAATATTATTTATGTTGAGCACTGTATATATAATTTTTGTTTATTTTATTTTTAACCAGAATGACCATTATTTTAATGCTTGAACTCTTTCTGTCTTTTTCAGAGTGGTAAAGTGAGTAGTGAGCGTCCTGCTCAGCGCTCTAAGAAAGTGAGAGACAATAAACCTAAAGTCAAGAAGCTGAAATA[T/A]CACCAGTATGTTCCTCCGGATCAGAAAGCTGAGCGTGAGCCTCCGCCTCTGCTCGACTCGTCCTACGCTAAACTCCTCTACCAACAGCAGCTCTTCCTCCAGCTACAGATTATCAACCAACAGCAGCAAAACTACAACTACCACACCATCCTGCCAGCTCCACCCAAGTGAGAAATGTCCTGTATTTGTGGAATGTTTATTATATACAATTGAAGTCAAAATTACTAACCCTGTTGTTGTTTTTTTTTCTTTTCTTTTTTAAATATTTCCCAAATTATGTTTAACAGAACAAGGATATTTTCACAGTTTTTTTTTCTTTTGGAGAAAGTCTTTTTTTTTTTTGGCTAGAATAAGAGCAGTTTTCAATTGCTTATAAACATTATAAGGTCAATATTTTTAGCCCCCTTAAGCTGTATTTTTTTTAATTCTCTACAGAACAAACCATCATTATACAATAACTTATTCTAATTACCCTAACTTACCTAGTTAACCTAATTAAC

Associated Phenotype:

Not determined