ZMP
si:ch73-190m4.1
Ensembl ID:
ZFIN ID:
Description:
Novel protein similar to vertebrate hect domain and RLD 3 (HERC3) [Source:UniProtKB/TrEMBL;Acc:B8JLD
Human Orthologues:
HERC5, HERC6
Human Descriptions:
hect domain and RLD 5 [Source:HGNC Symbol;Acc:24368]
hect domain and RLD 6 [Source:HGNC Symbol;Acc:26072]
hect domain and RLD 6 [Source:HGNC Symbol;Acc:26072]
Mouse Orthologue:
Herc6
Mouse Description:
hect domain and RLD 6 Gene [Source:MGI Symbol;Acc:MGI:1914388]
Alleles
There are 5 alleles of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa19588 | Nonsense | Available for shipment | Available now |
| sa44513 | Nonsense | Mutation detected in F1 DNA | Not yet available |
| sa482 | Essential Splice Site | Confirmed mutation in F2 line | Not yet available |
Mutation Details
This allele has been removed from public view.
Allele Name:
sa7914
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000111114 | Nonsense | 222 | 992 | 5 | 24 |
| ENSDART00000131544 | Nonsense | 222 | 350 | 5 | 8 |
| ENSDART00000140883 | None | None | 408 | None | 10 |
Genomic Location (Zv9):
Chromosome 1 (position 51126536)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 49975627 |
| GRCz11 | 1 | 50619453 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTTTACACAACAGACAGATTCGTCCCAACAGTTGTAAATAGTCTTAAA[C/T]GAAAGAAGATTGTGTCCRTCTCATGTGGAGGAGAACACACTGCAGCTCTA
Long Flanking Sequence:
GTTGACTGTTGAAATGTAAAGTTTTTGACCCAACTGGTTGAGTTATCAAATAAATAACCCAAAAAAAGCTAAAAATAACCCAACAAAGCACCAAACATTTAACCCAAGTGGTTGAGTTAATAATAAATAACCCAATAAAGGTTTAAAATAACCCAACAAAGCACCAAATATTTTACCCAACTAGTTGGGTTAATAATTAAAAACCCAATAAAGGTTCAAAATAACCCAACAAAGCACCAAATATTTTACCCAGCTGGTTGAGTTAATAATAAAAAACCCAATAAAGGTTCAAAATAACCCAACAAAGCACCAAATATTTTTAACTTAACAATTGTGTTAAATAAATGACCCAACGTTTTTTAGAGTGTGATGGCACTTTTAAAATAAGTTTAATGACACATAAAAACCAGTATCACAGAATAAAATATTTTAGAAGTGACCAATACACTGTTTTTTACACAACAGACAGATTCGTCCCAACAGTTGTAAATAGTCTTAAA[C/T]GAAAGAAGATTGTGTCCATCTCATGTGGAGGAGAACACACTGCAGCTCTAGCAAAGGTAGTATATTAAAATATGTTACATATTCATGTTTTAGATTTCACCAATATTTCCATCCGAATATACAACAAGCTGGACGGAAAAACGTTTGTAATTTTCAGGGAGGAACAGTGTTCACATTTGGATCAGGAGGTTTCGGTCAGCTTGGGCACAACTCATTTAAAGATGAACATCATCCACGACTGGTTGCTGAACTGTGGGGATCTAAAGTGTCACAGGTCACATGTGGGAGGTAAACTAGAGTCTTCAGTAGCTTTATTAGAAATAGGCCCACATGGAATCTGCGCGCCCAGATTTGCGTAGATTTTTAGTCCATCATTGATTCTGTTTATTTACTTGTGTGAATGTTTGTAAATTTATATTTATTCAGTTTTATTAATTTCAGTAATATTATTGACTGATTTAAAAATACTCAAATAATTCATTTACAATACAGTTTGTAAA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa19588
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000111114 | Nonsense | 332 | 992 | 8 | 24 |
| ENSDART00000131544 | Nonsense | 332 | 350 | 8 | 8 |
| ENSDART00000140883 | None | None | 408 | None | 10 |
Genomic Location (Zv9):
Chromosome 1 (position 51128099)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 49977190 |
| GRCz11 | 1 | 50621016 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACTGTAAACTAACTAAATGCTTCTCACACACAGAATATAATGACGAATA[T/A]ACAATTCAAAAACTTGTCGCGGGGGAGAATCATTCGTTTGCCTTGTATTT
Long Flanking Sequence:
ATTCTATGCAGAAAAAGCAAAAAATTTCCACAGATTCTGTTTGGCCCTAGCAAAAGGCAATTCAGAACAGCTGAGTTGTAAAGCTGAACTCTCAGTTCAGAGTTCAGCTTTATTTACTCAATAATTTCCCAAGTGAATTATTAATGACATTAAATAGTGAAGGTAAATTGAAATTCATACGCAACTCTGAAAAATGGCTCCAGCTGTGTTCAGTAATTTGACTTTTCATTTTTTCTGCATTAAGAAATCACACACTTGTATCGACTGCATCACCAAAGCTGATCTACTCATTTGGATGTGGGATGCAAGGGCAGCTGGGAAATGGAGAACAGGTCAAGCAGTCTGTGCCGTTACCAGTAGACCAGCCAACTGGTGACTTGGTTTTGTAGTAGCATAGTATTTTGTATATACATATATATTATATATATATTTATACATTAAGTAGATCAGAACTGTAAACTAACTAAATGCTTCTCACACACAGAATATAATGACGAATA[T/A]ACAATTCAAAAACTTGTCGCGGGGGAGAATCATTCGTTTGCCTTGTATTTCAAAGTAAGATGGATAGTTTTCATTCATAAATAGTTTGAAAGATAAATCACTGCTACACTGTGATGATTAATTATATGTTATGTTTTGTAGGAACTTGGAAATGAGGCTAATCCAGATCCAACCAGAGGGATTATGACATTTGATAACGGAATGATTGAACAATGCGAGTGTGGAAAAGATCCACGGAAAGCGATAAAGTGAATAAATGGCATCTTTATACTCTTTTCACTTGTTAGAAAATATCACAAACAATAATAAATAAATGGAAAATGACAATAATACAAGTTACAATTATAATTGTAATGCACTCTTTTAATAATTTCTGTTTCATTTTAAAAAATGTATATACACTCACCGGCCACTTTATTAGGTACACCTTACTAGTAGCTGGTTGGACCCCCTTTTGCCTTCAGAACTGCCTTAATCTTTCGTGGCATAGATTAAACAAG
Associated Phenotype:
Not determined
Mutation Details
This allele has been removed from public view.
Allele Name:
sa25667
Status:
Less stringent filtering
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000111114 | Essential Splice Site | 406 | 992 | 10 | 24 |
| ENSDART00000131544 | None | None | 350 | None | 8 |
| ENSDART00000140883 | None | None | 408 | None | 10 |
Genomic Location (Zv9):
Chromosome 1 (position 51129997)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 49979088 |
| GRCz11 | 1 | 50622914 |
KASP Assay ID:
2259-1104.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAAGTGTTCTCCTCTGCTGCATCTCTAAATGGAAGTTTTCTCAAAACAAG[G/A]TAAACTTTCGTTTGTTTTGGTACTTTTCCCACCAATGTATTAAAAAGAGA
Long Flanking Sequence:
CGTCTGGCACCAACAACCATGCCACATTCAAAGTCACTTAAATCACGTTTCTTTCCCATCCTGATGCTTTAAGCCACTTCTATACACCTTTAAGTGACATTTAAAGGCTTAACTAGGTTAATTAGGTTAACTTGGCAGGTTAGGGTAATTAGGCAAGTTATTGTATAATGATGGTTTGTTCTGTATATTATCAGAAAAAATAGTGCTTATAGGGGCTAAAAATTTTGACCTTAAAATGGTTTTAAAAATTAAAAACTGCTTTTATTCTAGCTGAAATAAAACAGATAAAACTTTCTCAAGAATAAAAAATATTATCAGACATACTGTGAAAATTTCCTTGCTCTGTTAAACATCATTTGGGAAATGTTTGAAAAAGAAAAAAAATTTAAAGGGGGGCGAATAATAATTGTGACTTTAACAGTTTGTGTATATGTTCGCAGGGACTTGAAAAAAGTGTTCTCCTCTGCTGCATCTCTAAATGGAAGTTTTCTCAAAACAAG[G/A]TAAACTTTCGTTTGTTTTGGTACTTTTCCCACCAATGTATTAAAAAGAGACACTTAGATTTCAGTGTAGATGTCTTTCTTTGTAGGCATGATGGTCATTATCAGACGTCTGAAGAGTATTGTGGTTTGGATTTTGGTCTGGTTGAATCTTCCATTGCAACTTTATCAAGGAATGAAAGGCTTATCTCAACGGTATGGTGAATCCAATATTTGCTAACAGGTTGCACCTAAAAAATGGAGGTGCTTTCCTGTTTATTCTAGTGTGTAAATATGACTCTTTTAACTAAGTTTTTAAGGGAGAGACCTTTGATGGGTGTATGTACACTGAAAAAGATGAAACTACAATGTCTTTCATTCAAAGTAGTTTTTTTTATATTGAATTAAGTGAAAATACATGGTTTCTGATTTTAACCTTTTTTATTTAGTTTGCCTCTAAGCGCAAAATTAACCCCTATGAAAAATTAAAAGCATTGTTTTTTTCCTAAAAGTGATTTTACTTTA
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa44513
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000111114 | Nonsense | 714 | 992 | 18 | 24 |
| ENSDART00000131544 | None | None | 350 | None | 8 |
| ENSDART00000140883 | Nonsense | 130 | 408 | 4 | 10 |
Genomic Location (Zv9):
Chromosome 1 (position 51135335)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 49984426 |
| GRCz11 | 1 | 50628252 |
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCAACGTGTTTAAGGAGCTTTGTGATCCAGCTTCTCAGCTCTTCATGTA[T/A]AACGACAACGAAACTATGATCTGGTTCCCCGCGAAGGTAAGGCAAAGACT
Long Flanking Sequence:
TCTCAGAGATAAATGGCTGTCGGTAAGCAACAAGAATGAGTTGCACACAGTACAGTGTTTGCATGTTTTGTTTTGATTTAATAACAAAGCAACAATTTAGTATGGAGGACAAATCCCTGCGGCTAGTTTCTTGATAGCTTGCTTCTTATCCAATTTTTAGTACTTCTAAAGCACATGTATTTATAATGCCTCATTCTGAATGCGTTTGTTAAAGCAATATAAATAAAATATAAATAAATAAAATGTAAATATAAACAAATAAATATAAATAAAATGTCAACCAACCTTAGTATAGGGAAGAATATTGCTTTGATAATCTGTCATGTTTGTGAAGGCTATTTATTAATTTCTTTTAATTTATAAGCTTTGGTATGAATTCATTTTTGGACACAGATTCTTTTCACTGAGAACGTGAGCAAAAGAACAGACGTCCACAAGAGGGACTTCTTTCTCAACGTGTTTAAGGAGCTTTGTGATCCAGCTTCTCAGCTCTTCATGTA[T/A]AACGACAACGAAACTATGATCTGGTTCCCCGCGAAGGTAAGGCAAAGACTTTTTTTATTATGTTAAAGGTTTATTTGTGATTGTTCCCATAACTCATTTTTACAGGATTATAGAATTATAGCACTATATGTACTTTTAATATTTAGATTAGTTCAGTGAAAATAAAATAAATAAAATATCTAATGATGCAAATTTAGATTTTTTTATTTAAATAACTTTTTGTTGTTGTTATTAATTTATAATCTACATTTTTATTATGATTTTATTATGATCACCAAAGATTTAGCAGTTGCAGATAGCTGGAGAACTACAAATCTTTAAATTTATCGAACTACAATTCCCATCATGCCTGGCACTCACACACCAGTTCTAGATCAGATTTTTGGAATTCACTTAGTGACCCCTACTCATTGTCCTGTGACCCCCACTTTGTGAACCACTGTTCTAGATTACCTCTTGATTTCACACTCACAGCTGCAGATCATCCTCATTGGTTACTT
Associated Phenotype:
Not determined
Mutation Details
Allele Name:
sa482
Status:
Confirmed mutation in F2 line
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000111114 | Essential Splice Site | 726 | 992 | 18 | 24 |
| ENSDART00000131544 | None | None | 350 | None | 8 |
| ENSDART00000140883 | Essential Splice Site | 142 | 408 | 4 | 10 |
Genomic Location (Zv9):
Chromosome 1 (position 51135372)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 1 | 49984463 |
| GRCz11 | 1 | 50628289 |
KASP Assay ID:
554-0333.1 (used for ordering genotyping assays)
KASP Sequence:
AGCTCTTCATGTATAACGACAACGAAACTATGATCTGGTTCCCCGCGAAG[G/T]TAAGGCAAAGACTTTTTTTATTATGTTAAAGGTTTATTTGTGATTGTTCC
Long Flanking Sequence:
GAGTTGCACACAGTACAGTGTTTGCATGTTTTGTTTTGATTTAATAACAAAGCAACAATTTAGTATGGAGGACAAATCCCTGCGGCTAGTTTCTTGATAGCTTGCTTCTTATCCAATTTTTAGTACTTCTAAAGCACATGTATTTATAATGCCTCATTCTGAATGCGTTTGTTAAAGCAATATAAATAAAATATAAATAAATAAAATGTAAATATAAACAAATAAATATAAATAAAATGTCAACCAACCTTAGTATAGGGAAGAATATTGCTTTGATAATCTGTCATGTTTGTGAAGGCTATTTATTAATTTCTTTTAATTTATAAGCTTTGGTATGAATTCATTTTTGGACACAGATTCTTTTCACTGAGAACGTGAGCAAAAGAACAGACGTCCACAAGAGGGACTTCTTTCTCAACGTGTTTAAGGAGCTTTGTGATCCAGCTTCTCAGCTCTTCATGTATAACGACAACGAAACTATGATCTGGTTCCCCGCGAAG[G/T]TAAGGCAAAGACTTTTTTTATTATGTTAAAGGTTTATTTGTGATTGTTCCCATAACTCATTTTTACAGGATTATAGAATTATAGCACTATATGTACTTTTAATATTTAGATTAGTTCAGTGAAAATAAAATAAATAAAATATCTAATGATGCAAATTTAGATTTTTTTATTTAAATAACTTTTTGTTGTTGTTATTAATTTATAATCTACATTTTTATTATGATTTTATTATGATCACCAAAGATTTAGCAGTTGCAGATAGCTGGAGAACTACAAATCTTTAAATTTATCGAACTACAATTCCCATCATGCCTGGCACTCACACACCAGTTCTAGATCAGATTTTTGGAATTCACTTAGTGACCCCTACTCATTGTCCTGTGACCCCCACTTTGTGAACCACTGTTCTAGATTACCTCTTGATTTCACACTCACAGCTGCAGATCATCCTCATTGGTTACTTGGACTATTTAAGCACCACAGCGACATTCATTTCTTGC
Associated Phenotype:
Not determined