Busch Lab

ZMP

il2rb

Ensembl ID:
ENSDARG00000075720
ZFIN ID:
ZDB-GENE-080108-2
Description:
interleukin 2 receptor, beta [Source:RefSeq peptide;Acc:NP_001121739]
Human Orthologue:
IL2RB
Human Description:
interleukin 2 receptor, beta [Source:HGNC Symbol;Acc:6009]
Mouse Orthologue:
Il2rb
Mouse Description:
interleukin 2 receptor, beta chain Gene [Source:MGI Symbol;Acc:MGI:96550]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa8784 Nonsense Mutation detected in F1 DNA Not yet available
sa11245 Essential Splice Site Available for shipment Available now
sa31329 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa8784
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112338 Nonsense 57 503 2 8
ENSDART00000122985 Nonsense 57 541 2 9
Genomic Location (Zv9):
Chromosome 3 (position 25300056)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 25068241
GRCz11 3 25198789
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
CTTGCGTRTGGTGGAACTATAGCAATTTCTCCAACCAGCAATGTGAGCTT[G/T]AGGTTAACTGTAAAATAAGGTTTGTGATTTTACTTCACTTCAAGTCAATT
Long Flanking Sequence:
ATGATTTATTTAAATTATTCAGCCTGACATGTTTACTGCTCCAAAATATTCTAAATGTTTGCTAAAATGAAATGTGTTCAAAGGGGAAATTTTATTTTTTACAAAGATATTTAAAAAGAGCTTTTTAGAGCAGTAATCACAATACCGTGAAACCATGATATTTTTACCCAAGGTTTTCATACCGTCAGAAACATATACCGGCCCATGCCTAAAGTTTACATTGAAAAACAATGGAAAATGTGTTCCGTCTCAATGGCCTATAAGAGTTCATATACTATCCAAACGTCAGAAGTATGAATTGTCTCTGAATGTTTGTTATTAGTACATCGATCTAATTTGAAACTATTGTAGAGACAAAACAAATTTACTTGTTTTCTATCCTCTAACTGTCTTCTGACTTACCATAAACAGGAGATCTGACCTGTGTGAATGACTACATGACAAACATTTCTTGCGTGTGGTGGAACTATAGCAATTTCTCCAACCAGCAATGTGAGCTT[G/T]AGGTTAACTGTAAAATAAGGTTTGTGATTTTACTTCACTTCAAGTCAATTTTAAACACTTATGAACAAGCCTTATTGAATTTGAATGTGTCTGTGTGCTAAAGTCCAAGCAGCCAATCAAAATCTTCCAGATGTGAGCTGGTGCCGCAGAACAACCTCTCAAATTCTCCCAGAAGCTGTTTTTTATTTTGTGAAAATGCTGTAAGTAGAAATTGAAATCTTTCATAAAATTGATTAAAAGAATTGTTTCCTTACATTTTACCTTTCTGTCACACAGTACTTCTTTTTCCTTAGCAAAATGGTATTGTCTGTGAGCTGTAATGGATCACTCATCAGCAGCCTGCATTATAAGCCAGGCCGACACAGTAAGTGGAAGTCATTTCGAATTTTTCTATTGTAAGTTGAAAAGTCTTTTTTGCCCTTCTGAAAATAAATCTCTTATATATTACACTTTACTTAAATTGGTTTCTAGTTCCAAATTTAATCTGGCTCCCATTTCAA
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa5202
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > T
Consequence:
Essential Splice Site, Missense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112338 Essential Splice Site 63 503 3 8
ENSDART00000122985 Missense 101 541 4 9
Genomic Location (Zv9):
Chromosome 3 (position 25300349)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 25068534
GRCz11 3 25199082
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTGTTTCCTTACATTTTACCTTTCTGTCACACAGTACTTCTTTTTCCTTA[G/T]CAAAATGGTATTGTCTGTGAGCTGTAATGGATCACTCATCAGCAGCCTGC
Long Flanking Sequence:
ATGAATTGTCTCTGAATGTTTGTTATTAGTACATCGATCTAATTTGAAACTATTGTAGAGACAAAACAAATTTACTTGTTTTCTATCCTCTAACTGTCTTCTGACTTACCATAAACAGGAGATCTGACCTGTGTGAATGACTACATGACAAACATTTCTTGCGTGTGGTGGAACTATAGCAATTTCTCCAACCAGCAATGTGAGCTTGAGGTTAACTGTAAAATAAGGTTTGTGATTTTACTTCACTTCAAGTCAATTTTAAACACTTATGAACAAGCCTTATTGAATTTGAATGTGTCTGTGTGCTAAAGTCCAAGCAGCCAATCAAAATCTTCCAGATGTGAGCTGGTGCCGCAGAACAACCTCTCAAATTCTCCCAGAAGCTGTTTTTTATTTTGTGAAAATGCTGTAAGTAGAAATTGAAATCTTTCATAAAATTGATTAAAAGAATTGTTTCCTTACATTTTACCTTTCTGTCACACAGTACTTCTTTTTCCTTA[G/T]CAAAATGGTATTGTCTGTGAGCTGTAATGGATCACTCATCAGCAGCCTGCATTATAAGCCAGGCCGACACAGTAAGTGGAAGTCATTTCGAATTTTTCTATTGTAAGTTGAAAAGTCTTTTTTGCCCTTCTGAAAATAAATCTCTTATATATTACACTTTACTTAAATTGGTTTCTAGTTCCAAATTTAATCTGGCTCCCATTTCAAGCGAGCATTAAATTTAGACCGTATATAGAATTAGGAATTGATCACATTTGTCATTCATGACTCAATTTACAGTCTTGATTGATATCTGATCCCATACTCTTGCCTTATACATTGATGCCACATAGAGTTTCACAGCCCCGGCATTCTCGACATTCTGAATTTAGTCAGAGGATGCAGGGTTAACTAATACCTCTTATTCTGGTTACCTCCTGCTCAATCATGCTCATCAAAGTGTAATCAATTTAATCACTTTCATGCCACTTGCTAAAAATCAGCAATAAACAGAAATCAAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa11245
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112338 Essential Splice Site 238 503 6 8
ENSDART00000122985 Essential Splice Site 276 541 7 9
Genomic Location (Zv9):
Chromosome 3 (position 25303710)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 25071895
GRCz11 3 25202443
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GTCTCATTATCATACCAATARTCATCTATAAAGTAAAGAAAAGCAGCCGG[T/C]GAGTATTRCATGTGTGTRTCTTGCCCTTGCNNNNTTTTTTTTAACAAAGTAACA
Long Flanking Sequence:
TTAAATAGAACATAAATAGTTTTTTTAATGGATGAAAAATTGAATTGAGTTGCATTGCATTGAAATTGTCTCGTATTTGTTGTATGCTTCTGTAGATGGCAAAACCCGGCCAACTCTCTCAAGAAAACTACACGCAGCTCAACCATGATTTACTGACTGTAGGAGAAGAATACCAGGCCAGGGTGCGTGTGAAGCCAGTTGAGCCGAAAACTGACGGTCATTTTCGGGGGGAATGGAGTGAATGGAGTCCTGCCGTATCCTGGAGGTCTGAGATTGGAAACCTACCAGTGAAACCAAAAGAGGATTCACCCAAAAGTGTGTTCTGTAAAATTACAATTTTTTTTCTCAAATTAAGATTGGACTATGCTATGATAACGGTTTTCTTTTGCTTTTCATCAGAGCGTGATAATATGCCTGTAATTATGATTGTTGGATTCAACCTACTGCTTGGTCTCATTATCATACCAATAATCATCTATAAAGTAAAGAAAAGCAGCCGG[T/C]GAGTATTACATGTGTGTGTCTTGCCCTTGCTTTTTTTTAACAAAGTAACATTATTATTTAGTACAATGTTTGTTCTTTAAAAAAAAAAAAATAATAATAATTAATAAATAAATAAATAATAAATGAATAAACTATATATACACACACACACACAAACACACACACACACACTACCACACACACACAATACCACACACACACACACACACACACACACACACACACACACACACACACGCACACACGCACACACACACACACACACACACACACACACACACACACACACACACACAGCAGCTTTACAAAAGGTAATCTGTTTGTTTGTGCCTGTATCAAGCATTCTCATTTCATTGCAGGCCATTAAAACCAATACAACATGTTCCAGACCCATCCAAATACTTCCAGCCTCTTCATACCATTCATGGTGGAAACTTCCGGGTAAGTTCAAAATGAAATTATTTAGTGTGTATGTGTTGTGTCACATTTTCGAAAATTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31329
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112338 Nonsense 254 503 7 8
ENSDART00000122985 Nonsense 292 541 8 9
Genomic Location (Zv9):
Chromosome 3 (position 25304116)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 25072301
GRCz11 3 25202849
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GCAGGCCATTAAAACCAATACAACATGTTCCAGACCCATCCAAATACTTC[C/T]AGCCTCTTCATACCATTCATGGTGGAAACTTCCGGGTAAGTTCAAAATGA
Long Flanking Sequence:
TAATATGCCTGTAATTATGATTGTTGGATTCAACCTACTGCTTGGTCTCATTATCATACCAATAATCATCTATAAAGTAAAGAAAAGCAGCCGGTGAGTATTACATGTGTGTGTCTTGCCCTTGCTTTTTTTTAACAAAGTAACATTATTATTTAGTACAATGTTTGTTCTTTAAAAAAAAAAAAATAATAATAATTAATAAATAAATAAATAATAAATGAATAAACTATATATACACACACACACACAAACACACACACACACACTACCACACACACACAATACCACACACACACACACACACACACACACACACACACACACACACACACGCACACACGCACACACACACACACACACACACACACACACACACACACACACACACACAGCAGCTTTACAAAAGGTAATCTGTTTGTTTGTGCCTGTATCAAGCATTCTCATTTCATTGCAGGCCATTAAAACCAATACAACATGTTCCAGACCCATCCAAATACTTC[C/T]AGCCTCTTCATACCATTCATGGTGGAAACTTCCGGGTAAGTTCAAAATGAAATTATTTAGTGTGTATGTGTTGTGTCACATTTTCGAAAATTTGGTTTTAGTATTTGATTAAAGACATCTATCATGCTTAGCAAGGTGATGCTGATTTAAAGAGGACCTATCATGCCTATTTTTACAAGTCTGTAAAATAAGTCTCTAATGTCCCTTTAGTGTGCATGTAAAGTTTCAGCTCAAAATACCCCACAAATATTGTTTTACAACTTTTTAAAATCTGAGGCTCAAATGACGCGAATTGCACGATAGGAGCGGTGCAAATGGCGTGATACTCGCAAATTGAGTATTTTGCGCGTTTGACTTGCTTAATGCGCGTTTTGCGCGAATCGCTCTAGGTTGAAAATCTAAACTTCAGTGGACATTCGCCCCGCGTTAACCAATCAGAAGCTTGCTCTTGTGGGGGCGTGATTGTGACGTATCACCTGTTTTCGGTGTCCCGGGGAAAT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa3430
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000112338 Nonsense 444 503 8 8
ENSDART00000122985 Nonsense 482 541 9 9
Genomic Location (Zv9):
Chromosome 3 (position 25308260)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 25076445
GRCz11 3 25206993
KASP Assay ID:
2259-3440.1 (used for ordering genotyping assays)
KASP Sequence:
CATTGGTTTCCTTCATTATGTCACTGTCTCAGGGTGGCGTTCAGCCGGCT[G/T]AGGKTTTCCCTCCAGTRCCTGTCTTCTCAGCCTGGTCTGAACTTGTAAAG
Long Flanking Sequence:
TTCTTACGCCTCAATCCAGTGATGACATCTCACCCGTGGAGGTCTCCGATATGTGGGACGTCTCCTTAATGGATCCCGATGCCCAGATGTCCACCACCATGCTAGTTCACGCCGGTCAGGTGGACTCTGGAGTGGAGAACAGCGGCACCAGTAAAGCATCGTCCTCCTCAGGTTTCTATAACATGGGCTACTTCTATAGCAAATCTCATACTGGCTCACTCTACCTGGAATCCTGTCCCGTGTATTTCTCTTACCACCCTGATGAGGGCACCCACTCTTCTCTCTCATCGTCCAGCTCTTCGTGCCACTCTTTGGGATCCCCAAGTTCCCTGCCGGAGCAGCCGATGAGCCCGGATTCAGGATTTGCCATGTCTGATGAGCAGCATTGTGAGGATGATGGAGATGGTGAAGAGATAGGAGGCGCGGAGAGAGCAGTGGCAGAAGGAAAGGCATTGGTTTCCTTCATTATGTCACTGTCTCAGGGTGGCGTTCAGCCGGCT[G/T]AGGTTTTCCCTCCAGTACCTGTCTTCTCAGCCTGGTCTGAACTTGTAAAGGCGCCCAGCTGTGCTTCTCTCTGTGAGCCAGCAGAGAGCACTGCACTCAGACCTGCCTCCATGATCGAGCCCAGCGGGAGCGGATATCTCACCCTGAAGGAGATGCAGAAGTACAGCAATAAATCCATCTGAAAGAAGGTTCATGGGTAGATCAGTGCAGGATAAAAAAAGTATGAACTGCCTTTCAAATGTTTAGAGTTGGTTATATAATAAAAGTTCCCTTTATTTAGTCACCAAGGCTGTATTTTTAAAATCAAAAATACATCAAATCAGTAGAATTGTTAAATATTATCAAAATGTAAAACAACCTTCAAATATAATTCATTCGTGTGATGATTTTTAGCAACATTACTTCAAATCTTCAGTTACACAAGCCTTTTGAAAAATCACTGTAAAATGCTGATTTGAAATGTTTAGTATAGGCCAGTAGCCAGGTAGGGTTCGGGTGGT
Associated Phenotype:
Not determined