Busch Lab

ZMP

arhgap21b

Ensembl ID:
ENSDARG00000075673
ZFIN ID:
ZDB-GENE-030131-4944
Description:
Novel protein similar to human and mouse Rho GTPase activating protein 21 (ARHGAP21) [Source:UniProt
Human Orthologue:
ARHGAP21
Human Description:
Rho GTPase activating protein 21 [Source:HGNC Symbol;Acc:23725]
Mouse Orthologue:
Arhgap21
Mouse Description:
Rho GTPase activating protein 21 Gene [Source:MGI Symbol;Acc:MGI:1918685]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa19692 Nonsense Available for shipment Available now
sa32859 Nonsense Mutation detected in F1 DNA Not yet available
sa32860 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa19692
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091298 Nonsense 449 1793 7 24
ENSDART00000134083 Nonsense 359 1703 4 21

The following transcripts of ENSDARG00000075673 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 12171140)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 12696365
GRCz11 2 12379151
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TCGTAGTGTGTCCTCTGATGGTCTCATACGGAAGCCCCGTGCTCATTCAT[C/A]AGACTATGTGGAACATGGTGAACTAGTTTCTGCTGCACCATGGGCAGCAC
Long Flanking Sequence:
TATCCGAGCCAGGCCTGGAACTGTGTCTGGTGGTCGTCCGCCATATCTACACCCGCGCAAAGCTGACATGTTCCCGTCAGGTTACCATGGTGATCCTTATGCCATTCCACCCACACACTATGTGCCTGCTTCCTCAATCACCTCCCCTGCTACTCACCAGAACATTGACTGGCGGACTTACCAGACATACCGGGAATATATTGACAACAAAGGTATTCATGCTTACAGTCGAACTGTTCAAGAACGTTTAGACAGCCTGCGAGCTGCATCTCAAAGTACACATGGTGGCCCTCACTGTGGACCCCAACCTGGCTGGGGCAATAAGTTACGACGCAGAAGTACGTCTCATGATCGGGCCTACCAGGGCCCTTCTATGCTTCCTCCACGCAGTGCTTCGCAGGATAGGATGAGTGGGGCAGAGAGAGCAGCTCACGCCAGGGACTGGCCTCCTCGTAGTGTGTCCTCTGATGGTCTCATACGGAAGCCCCGTGCTCATTCAT[C/A]AGACTATGTGGAACATGGTGAACTAGTTTCTGCTGCACCATGGGCAGCACCTGTGGATAGGCAGCTTTATAGCAGAGTAGACCAGAGGAGTCGTCCCAGTAGACAGTCTCTCCCACCAAGGGCGGTGCTTTACCGCCCACCAACAGGGTATGGTATGAGCGTCAGGGGTAATGCTGGCTCCCATAAGCATAGCTCCAGAACGGATATCCCACCTACTGCTGGTTTTCCAGAGCGACCTCGCAATGGAATAAACCAGGCCAAAGAACCTCCTTCCAAAGACCAAAGTGGAACTGTAGTTGGAAATCGAATTTTAAATTCTGCATCAAACCAATCAAGAACTAGGGCTGAAACCATGCAAAGCCCAGAATCTGGGAAAGATATTTCTGTAGGATATAGGTCGGCATCTTACTCTGCTCCACCTCTTCAAAGGCCCAAGGGTGGTGCATCAACTCAGAGGACAAGCTCGAGGGATGTCAAGGGCTTACCAGTAAATGGGTCTA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32859
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091298 Nonsense 484 1793 7 24
ENSDART00000134083 Nonsense 394 1703 4 21

The following transcripts of ENSDARG00000075673 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 12171244)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 12696469
GRCz11 2 12379255
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGGATAGGCAGCTTTATAGCAGAGTAGACCAGAGGAGTCGTCCCAGTAGA[C/T]AGTCTCTCCCACCAAGGGCGGTGCTTTACCGCCCACCAACAGGGTATGGT
Long Flanking Sequence:
TTCCACCCACACACTATGTGCCTGCTTCCTCAATCACCTCCCCTGCTACTCACCAGAACATTGACTGGCGGACTTACCAGACATACCGGGAATATATTGACAACAAAGGTATTCATGCTTACAGTCGAACTGTTCAAGAACGTTTAGACAGCCTGCGAGCTGCATCTCAAAGTACACATGGTGGCCCTCACTGTGGACCCCAACCTGGCTGGGGCAATAAGTTACGACGCAGAAGTACGTCTCATGATCGGGCCTACCAGGGCCCTTCTATGCTTCCTCCACGCAGTGCTTCGCAGGATAGGATGAGTGGGGCAGAGAGAGCAGCTCACGCCAGGGACTGGCCTCCTCGTAGTGTGTCCTCTGATGGTCTCATACGGAAGCCCCGTGCTCATTCATCAGACTATGTGGAACATGGTGAACTAGTTTCTGCTGCACCATGGGCAGCACCTGTGGATAGGCAGCTTTATAGCAGAGTAGACCAGAGGAGTCGTCCCAGTAGA[C/T]AGTCTCTCCCACCAAGGGCGGTGCTTTACCGCCCACCAACAGGGTATGGTATGAGCGTCAGGGGTAATGCTGGCTCCCATAAGCATAGCTCCAGAACGGATATCCCACCTACTGCTGGTTTTCCAGAGCGACCTCGCAATGGAATAAACCAGGCCAAAGAACCTCCTTCCAAAGACCAAAGTGGAACTGTAGTTGGAAATCGAATTTTAAATTCTGCATCAAACCAATCAAGAACTAGGGCTGAAACCATGCAAAGCCCAGAATCTGGGAAAGATATTTCTGTAGGATATAGGTCGGCATCTTACTCTGCTCCACCTCTTCAAAGGCCCAAGGGTGGTGCATCAACTCAGAGGACAAGCTCGAGGGATGTCAAGGGCTTACCAGTAAATGGGTCTAGTCCTGTGGAGGGTGTAGTCCTCAGAGAGAAACCGCCAACAGGGAAGGGGACCCCACAACCTCTCCGCCATCCCTCGTACATCCTTGCAGTAAATGACACGGAT
Associated Phenotype:
Not determined

Mutation Details

This allele has been removed from public view.

Allele Name:
sa3410
Status:
Allele not cryopreserved
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
n/a
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091298 Nonsense 1022 1793 15 24
ENSDART00000134083 Nonsense 932 1703 12 21

The following transcripts of ENSDARG00000075673 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 12186808)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 12712033
GRCz11 2 12394819
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GAGATAAAGCTGCGTGGAGAAGAGGTATTCCAGGTTTAAAGAAAAAGCCA[C/T]AAGATAAGARGCCTGCTGCTGGCGTCACATTTGGAGTACGACTGGATAAC
Long Flanking Sequence:
GGGGCCCCCTAATCACGCGGGGCCCCCCTGCGGTGCGTGCGGTGCGTGCCCTGCGTGCCCGTCCGCTACGCCACTGTCCCCAACACTGAACATGAATTGGTAAATATTTGAAAAAGAAATGCATTTTCCCAGGAGGGCTAATAGTTTAGCCTTCAACAGTATATGTTGCCATGTGTTAGCTTGCCTTGTGTTTAGTGTCCAATAATGAGTGTGTTTTTGGTAACAGTGCACCCAGCAGTAAGACAGAACCGTCGCCAAAGACCTCACGGCAGTCTCTCAGCATTAGACAAACTCTGCTTGGTGGCAGCAGTAAAAGTCAAAGCCCCTACTCACCCAAAAATGAACAGGACAGGAGTAAAGGTAATTAAGAAATAACACTGAAACCCATCAATGTCAGTGAAATGTTTTTCTGATGTCAGCGTTGTGTTTCAGATGACTCTAGTCCTCCGAGAGATAAAGCTGCGTGGAGAAGAGGTATTCCAGGTTTAAAGAAAAAGCCA[C/T]AAGATAAGAGGCCTGCTGCTGGCGTCACATTTGGAGTACGACTGGATAACTGCCCTCCTGCGCAAACCAATAAAGTAAGTGATTTAAACATGTCATTAGTTATGTTTTCATTAAAAAATGTGAATGAACTTTGTGCAAAACTGAAATCTCGCATAAAAGATCTGAATAAAGTAGCGTTTTCATCCAACGAGTCAAAGAGAACAAAATCATCACTTCCTGATTATCTGGCGCAAAATATCAACAGTAAAAACGGAATTTGCTGCGGTAGGAGAAGCTGCATCAATCTTTTCTTTTCTTGTAAGATGCAGAGCACAGACGCTCTTGACAGTTCTGGAGGTAATTAATAAAATAATAACTTTAAAATGAATGACTAAAATTCACAAAAACATACACAAACACACACACACACATATATATATATATATATATATATATATATATATATATACATACACACACACACACACACATATATTCACAATGTGCTCAGCCTGCTGGTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa32860
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000091298 Essential Splice Site 1046 1793 None 24
ENSDART00000134083 Essential Splice Site 956 1703 None 21

The following transcripts of ENSDARG00000075673 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 2 (position 12186884)
Other Location(s):
Assembly Chromosome Position
GRCz10 2 12712109
GRCz11 2 12394895
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACATTTGGAGTACGACTGGATAACTGCCCTCCTGCGCAAACCAATAAAG[T/C]AAGTGATTTAAACATGTCATTAGTTATGTTTTCATTAAAAAATGTGAATG
Long Flanking Sequence:
TCCCCAACACTGAACATGAATTGGTAAATATTTGAAAAAGAAATGCATTTTCCCAGGAGGGCTAATAGTTTAGCCTTCAACAGTATATGTTGCCATGTGTTAGCTTGCCTTGTGTTTAGTGTCCAATAATGAGTGTGTTTTTGGTAACAGTGCACCCAGCAGTAAGACAGAACCGTCGCCAAAGACCTCACGGCAGTCTCTCAGCATTAGACAAACTCTGCTTGGTGGCAGCAGTAAAAGTCAAAGCCCCTACTCACCCAAAAATGAACAGGACAGGAGTAAAGGTAATTAAGAAATAACACTGAAACCCATCAATGTCAGTGAAATGTTTTTCTGATGTCAGCGTTGTGTTTCAGATGACTCTAGTCCTCCGAGAGATAAAGCTGCGTGGAGAAGAGGTATTCCAGGTTTAAAGAAAAAGCCACAAGATAAGAGGCCTGCTGCTGGCGTCACATTTGGAGTACGACTGGATAACTGCCCTCCTGCGCAAACCAATAAAG[T/C]AAGTGATTTAAACATGTCATTAGTTATGTTTTCATTAAAAAATGTGAATGAACTTTGTGCAAAACTGAAATCTCGCATAAAAGATCTGAATAAAGTAGCGTTTTCATCCAACGAGTCAAAGAGAACAAAATCATCACTTCCTGATTATCTGGCGCAAAATATCAACAGTAAAAACGGAATTTGCTGCGGTAGGAGAAGCTGCATCAATCTTTTCTTTTCTTGTAAGATGCAGAGCACAGACGCTCTTGACAGTTCTGGAGGTAATTAATAAAATAATAACTTTAAAATGAATGACTAAAATTCACAAAAACATACACAAACACACACACACACATATATATATATATATATATATATATATATATATATATACATACACACACACACACACACATATATTCACAATGTGCTCAGCCTGCTGGTTTGTCCATTTACACACATTTTCCTCATTCCATGATCTCTTATAACAAAATCACATGAACTTTTTCAATGCGCATATT
Associated Phenotype:
Not determined