Busch Lab

ZMP

si:ch211-236d22.1

Ensembl ID:
ENSDARG00000075201
ZFIN ID:
ZDB-GENE-090312-97
Description:
type II inositol-3,4-bisphosphate 4-phosphatase [Source:RefSeq peptide;Acc:NP_001139046]
Human Orthologue:
INPP4B
Human Description:
inositol polyphosphate-4-phosphatase, type II, 105kDa [Source:HGNC Symbol;Acc:6075]
Mouse Orthologue:
Inpp4b
Mouse Description:
inositol polyphosphate-4-phosphatase, type II Gene [Source:MGI Symbol;Acc:MGI:2158925]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa30588 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa19605 Nonsense Available for shipment Available now
sa18139 Essential Splice Site Available for shipment Available now
sa31235 Nonsense Available for shipment Available now

Mutation Details

Allele Name:
sa30588
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
G > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108492 Essential Splice Site 464 760 10 17
ENSDART00000147683 Essential Splice Site 531 827 13 20

The following transcripts of ENSDARG00000075201 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 53681751)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 52551322
GRCz11 1 53186060
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CACAGGGTCTGCAGCTCCAGCAGAGACGAGACACCGTTTTCAGCCAAGCT[G/A]TAAGTCTCACAGAAGAAAAACAAGATTTTCACACTGAGGGTGTTCATTGC
Long Flanking Sequence:
TAAGAAATATTATGTTCAGATTGTCTACAAAACAAACCACTGTTATACAATGGCTTGCCTAATTAACCTAATTAACCTAGTTAAGTCTATAATTGTCACTTTAATCTGAATACTACTATCTTGAAAAATACAACTCAGTACTGGGAAACACCCATACACACTCTGATTCACACACACTCATACACTACGGACAATTTAGCTTATCCAATTCACCTATAGCGCATGTGTTTGGACTGTGGGTGAAACCGGCGCTCGATATATTGTGCAGCCCTAATACAAGTAAACTTAAATTGAATGTTTTTTCCTCAGATCGCCCCATGGATGTGGTGGACTGGCGGGATCAGCTTGGGGTCCTGGTGCAATCGCTGAAGGAGTGTGTGCTGGATGTGGCAGAGAGAGCCAGACACTCCGTCATCTTTGTGCTGCTCCAGGAGGCGGCGTGCAGCACGGCACAGGGTCTGCAGCTCCAGCAGAGACGAGACACCGTTTTCAGCCAAGCT[G/A]TAAGTCTCACAGAAGAAAAACAAGATTTTCACACTGAGGGTGTTCATTGCATGAAACTGTTATTTAAAGTACTCATGAAATCAAAACTAGCCATAATGATTTTGTTAGCTCACATTGCTAGTTTTATGGTGAGCAATTCATCTGTGCATGTCCTTAAGAAAAAACAGCAGCTTGTTTTGTGACTCCCTGAAAACCCCACTGCAGTTTACTGAACTGAAGCCTTCTAACTTTAAGTTTGCCTTGAGGCGACTTTATATTTGGTGGACATTTGCAGAGGTAATATCTGGATCGATTGCAACCTTGGCTGTCATTGAACCAAACTGAACAACATTGAGCTGATAATGGCACTATTCCTCTGTAGAGCTGCTTCATAACTGAAAACAGCCCTCTGGATACATTTATGTGACAAACGTAAAACATGTTGCTTTAGGTACATTTCCTTGCACATTTCAGATGACAAATCCACTAGAGGGCGCTGTCTACATTTTTGTGAATCTGAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19605
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108492 Nonsense 551 760 13 17
ENSDART00000147683 Nonsense 618 827 16 20

The following transcripts of ENSDARG00000075201 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 53691681)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 52561252
GRCz11 1 53195990
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GTATTGATGCTGTGTGGAAATGTGACCTGTTTTAATGGCAGAGACCGTTA[C/A]ACTGTGGAGGTGCCTCTGCCACATGATGCCTTCCAGACGCTGCCGGATGA
Long Flanking Sequence:
TGAGATATGAAAAAGTATACACAGCGCCCTCTGGTGGATTTACAAAAACTGCAAAAAAAAAATCCTCCTGGGATGTATTGGGCGCTCTCCAGAAATGTATATAGGGGTACATAATCAGAATGAGCCTGGGATGACCAAAACACCTAATTACGATTAATTAGGTGTTTTGGTCATCCCAGGCTCATTCTGATTATGTACCCCTATATACATTTCTGGAGAGCTACCAAACAGTTTTTCATCAAAGCAACAAAATGCACACTTAATCATGAAAGCATCCAACATTAATCACCAAAGCATCACAACACACAATTAACCACATAATCACAATTATTTCATAGACAATTGATCGTCTGCCAGATTTCCTTTTGGACAGTCCTAATTGCTGATATGCATGCAGTCTAAAACGAGTATCAACAGAAAAGCAGCTACTGTGTGAACCTGTGCGTGATAGTATTGATGCTGTGTGGAAATGTGACCTGTTTTAATGGCAGAGACCGTTA[C/A]ACTGTGGAGGTGCCTCTGCCACATGATGCCTTCCAGACGCTGCCGGATGAGCTGCGCCAGGGCAAGCTGCTACACGTCATCCCTGTGCTCTTCAATGTGGGCATCAACGAACAACAGACCATCGCTGAGAGGTACAGATGGTCTTTACATGTTATAGTACATAGCTCAATTAACGTCATTACGTCACCATTCGATGCTAGTTTCAAGCAATGCTAACAGTTTGTGTTCGTCATGGCATCATATGTGATTTACATTTAGTCTTTTAGCACAGAGGTTCTCAAAGTGGGGGTCAGGACCCCGAAGGGGTCGCCGGACAATGAGGGGGGCCGGGGGTGGGTGGGTTTATAATTGTCTGGTGGTTTCCAAAAATCTATTTATTTTTAAGAATTGCCATATTTTATCCATAACCTACTGAAAAGAAAAAATATTCGTTTATAGTTACTATATACTATATAGTTACTATAGTAGCTTATAGTTACTAGTTCTATTGGATTGCGCCC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18139
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108492 Essential Splice Site 665 760 15 17
ENSDART00000147683 Essential Splice Site 732 827 18 20

The following transcripts of ENSDARG00000075201 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 53697716)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 52567287
GRCz11 1 53202025
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AGTGACCAAGAAGAGGAAGAACRTGGAGATATTGTGGCTTGCAGGAACGG[T/A]GAGAGTTTGAGGAGTCTGTGCAGGAANNGTGTGTGTGTGCAAGATCTTTCAC
Long Flanking Sequence:
CTTCTACAATTGCAGGATTTCGTTCTTTAGCCCTCTTTTTTATTCATGCAACACGTCCGCATGCGTCTCCTTCTCAGTGTTTAATGCTGAGCATATCGCCTCATATTTCAAGGATTCGAGTGCAGGAATTTGTTTCTCTGATATGTCAATCACGTCTGCAGAGCGTGACGGCTTCAGATGATGAATGATCCCAGCAGACGAATGCCAAACTGCATCTCAGCATGTCACATCTTGTCTTCCATCCATCTCCCTGTTTATCAGAAAAAATGTCCCTAGACTTTTTCCCATCTGATCTTTAGTACTCGTCTATACAGAGACAAAACAAGGCCTAAGCCGCAAATGCATGACATGTCAAGTGTTTCTCTCTTCTGTCTTCTGTTCAAAAGGTCTGCCGAGTTTTCAGACGCAGACGGACATTAAGGAGCTGCTGGAAACGCTCGGACAGAATGTAGTGACCAAGAAGAGGAAGAACGTGGAGATATTGTGGCTTGCAGGAACGG[T/A]GAGAGTTTGAGGAGTCTGTGCAGGAAGTGTGTGTGTGCAAGATCTTTCACAACCTCGCATTTGCAAAATGCTTGCAGGATCAGTGTGATGAATTAACATTGTCATCAAAGTTCAGAATGTTCGCTTTTTAGTCGTTTGTTTGTCCTCTGGGCATTCACGTTTGAGCAGAACATCCATCTTATTATTCTGCATGCATTAAAGCAGGGGTCTTGAACTCAAATCGGCTGGGGGATAATAATCACGGTGCTCAATTCAATTACTATTAGGGATGCACCGATACGCCAGCGATGCGGTGGCGCAGTAGGTATTGTTGTCGCCTCACAGCAAGAAGGTCACTAGGTCGATGGTTCGAACCTAGGCTCAGTTACTGTTTCTGTGTGGAGTTTGCATGTTCTCCCTGCGTTCGCGTGGGTTTCCTCCGGGCGCTCCGGTTTCTCCCACAGTCCAAAGACATGCGGCACAGGTGAATTGGGTAGGCTAAATTGTCCGCAGCGTATGAG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa31235
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000108492 Nonsense 667 760 16 17
ENSDART00000147683 Nonsense 734 827 19 20

The following transcripts of ENSDARG00000075201 do not overlap with this mutation:

Genomic Location (Zv9):
Chromosome 1 (position 53704252)
Other Location(s):
Assembly Chromosome Position
GRCz10 1 52573823
GRCz11 1 53208561
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AGAAAGAGAAAGTGTACTCAATGGTCTGTCTGTGTGTGTTGTCAGATCTG[T/A]CGACGGATGAATGGTATCCGCTTCACCAGCTGTAAAAGTGCCAAAGACCG
Long Flanking Sequence:
AAAATAAATAAAGTAAAAGTTTGGTCGGATTGGTTGGTCGGTCAGTCAGTCATTCAGTCCGTCAGCAACAGCAGCCTCTGGTGGATATACAAGAGAACTGCAGGCATGAATGGAACTCACGAGAGAAATTCAAAATCTTAAAAAGCATGCACAGCGCCCTCTGGTGGATTTGTAAAAATAAAAACTACAAAAAAAAAGTACCTTCTGGGATATATTTGGCGCTCTCAAGAAATATATATAGAGGTACGTAATCAGAATAAACCTGAGTTTAAAAAAAAATTAAAAATGAGTACTATAATTTTACTTTTAACAAAAAAATTTCATTTTCGTCAGGGTAGTAAATGCAGTTGTACAAATAGAAGTCAATGCGCCCAGTGAGCCCAATATAATCATAAAAAAGCATGATTCATTTATGCAAGGGCATGAGCTCAAACTCTAAACACCATATTGAGAAAGAGAAAGTGTACTCAATGGTCTGTCTGTGTGTGTTGTCAGATCTG[T/A]CGACGGATGAATGGTATCCGCTTCACCAGCTGTAAAAGTGCCAAAGACCGGACGTCAATGTCGGTGACGCTGGAGCAGTGCTGTCTGCTGCGGGACGAGCATCAGCTCAATAAAGACTACTTTGTGCGCGCTTTGGACTGCATGAGGAGGTAAGAGGAGTCCACATCCATCATTCCTCCAGCATGCATAAGTACATTCAACTTAAACCCTTCACTATACAAGTGCATCTGGTCAGACTGGGTTTTTCACAGATGAAAGCCATTTAAAGGGACTGTTCACCCCAAAATGACAATTTGTTTATTATTTACTCATCCTCAAGTGGTTATAAATCTTTATGAGTTTCTTTCTTCTATTGAACTCAAAAGGAGATATTTTGAATAAAGCTGAAAACCTGTAACTGCTGACTTCAATAGTAGGAAAAACAAAGGAAGTCAATGGTTACAGGTTTTGAGGAAGTTTTCAGTACATCTGAAACAGAAGAAAGAAACTTTTAATGAGTT
Associated Phenotype:
Not determined