Busch Lab

ZMP

LOC557486

Ensembl ID:
ENSDARG00000075139
Human Orthologue:
HDAC5
Human Description:
histone deacetylase 5 [Source:HGNC Symbol;Acc:14068]
Mouse Orthologue:
Hdac5
Mouse Description:
histone deacetylase 5 Gene [Source:MGI Symbol;Acc:MGI:1333784]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa8948 Nonsense Mutation detected in F1 DNA Not yet available
sa33155 Essential Splice Site Mutation detected in F1 DNA Not yet available
sa40058 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa8948
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111435 Nonsense 511 1085 11 25
Genomic Location (Zv9):
Chromosome 3 (position 23246079)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 22824290
GRCz11 3 22954838
KASP Assay ID:
2259-3367.1 (used for ordering genotyping assays)
KASP Sequence:
CGAGCCACGCCTCTRTTCAGATTCTTTCTAAAGGGACGGATCTTCCAAGA[C/T]AGCCTCCCACTCACCCAGAGGAGACGGARGAGGAACTTACGGAAACCGCA
Long Flanking Sequence:
ATTAAGTGCTATGATGAGATACTGGGGCTGCGTCAGAAATTGCATACTTCCATACTATATAGTACGCTAAAAACAGCATGCATGCCGAGTAGTATGTCCAAATACATAGAAATCGAAAATCAGTATACGAGAAGTACACCGATGACCTACTACTTCCGGCGAGATTCTGGAGTGTGCATCCGATGTATGCTGCGCTATCCCAGGATGCCCCACGAGAGAATTCATAAATGGGGGTGAAGCGGCATAACTCGTTTAGGTCACATGATCATGACAAAATGGCAGATGTAGTATGTCTGAGTTCCATTCATGCTGCTCACATACTGTATAGAACATACTTTACTAATGGCGTTAGTAATACGTTTAAATTCAAATGCAGTAACCTACTGAGAAGTTGGCTGTTTCAGGTACAGCCCTGATGTTTGGCTTGCGATTATTTAAATTCCTTGCTAACGAGCCACGCCTCTATTCAGATTCTTTCTAAAGGGACGGATCTTCCAAGA[C/T]AGCCTCCCACTCACCCAGAGGAGACGGAGGAGGAACTTACGGAAACCGCAGAGATGCAGGACGAGCGAGGGGAGGGGCCTGATCATGTAAGGGAGGGGTTACAGAAAGACAGCTCTGGTGAAACCACACCTCCCTCTGAACGCATAGTTCCGCTGAAGGGAGAAAGCACGGAAAGTGACTTGGAAGAAGAAGATGATGAAGATGAAGCGGTCGAACTGAGGGAGTGTGATGAAGACGCCCCTTATGGCCAGGTGAGGAATTACAGCTTATTGCCTCTCTTAGAAGGTTTTTGTTTGTAATTTAAATTGACGTGTACAATTTCTGCACCATAAGATTGCAATAATCATCACTATATTTGTTGAGATGCTAAAGACATCTGGGATTGGCCTGACAGATAGCCTGCCCTGCCCTAAATTCTTGCTATTTTGACTCATTTCAAAAGCCTTGAGCATGTACCTGGCATGTTTTAGCTTGCAAAGATCTCTCTTAAGCTTTTAAAC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa33155
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
A > T
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111435 Essential Splice Site 595 1085 12 25
Genomic Location (Zv9):
Chromosome 3 (position 23253251)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 22831462
GRCz11 3 22962010
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AACAAAACTGAGCTGCGCTGAATAAAGGTTGTTTGTGTGTTGTTTCCCTC[A/T]GTATTTGGACCAGCAGCATGTGCAGCAGCTCAACGTGTTCCAGGCCTCTC
Long Flanking Sequence:
TCAATAGGGTAAGTAAAATATTGTTTTTGCTTTGAAATGTGGATATTTGGATGAGAAACAAAAATAAAAAATTTAAGAAAAAACCTATGTTGCATAAATTGTATGAATATTGATTAAATACAATTTTGCAGCCCCTTGTCAACAATAATCCATTGCATATCTTTGTGATATGACTATTGTGGATGCACACATTGCGATATTGGTGCTGAAACGATATATTGTGCTATAGTTTAAAAACGTTTAGATCAAATGAATTGAACCAAACAGAACAAATTTCTTTAACACTTTTTTTCTTTTATTAAATTAATCTGTCCTGAAGAGAAGCATACATATTTGATATGTAAACTGTAGAATTAAACTAAACTGAACAGAAACGGTTCATAGTGGACTTAAATATGAGATTAAATAAAAATGAATTGATTGGTTCAGCGTGAACTAAATTATGAACAGAACAAAACTGAGCTGCGCTGAATAAAGGTTGTTTGTGTGTTGTTTCCCTC[A/T]GTATTTGGACCAGCAGCATGTGCAGCAGCTCAACGTGTTCCAGGCCTCTCTGTCCATCACAGGAATGCCCCACAGACCCCTGGGAAGGGCTCAGTCGTCCCCTGTCACCTCCAGTCTTAAAGGAACAACCCTGAACGAGGTGCCCATTAAGCATCTCTTTACGACAGGTAATAATGATGTGGAAAATCTTTTGAAGCTTTAGCACATGCGATTGATATTGATAAGACTTGAATTTTGGATGATTTGGTCACTGCCTGTGCAGGGCTGGTTTACGACACCTTCATGCTGAAGCACCAGTGCATGTGTGGAAATACCAACATTCATCCCGAACACGCGGGTCGCATTCAGAGCGTTTGGTCCAGGCTGCAGGAAACAGGACTGCTGGGCCGCTGTGAGGTGAGTTTGAGGCGCCACCTGCTGGAAGGGTGGAGGAACAGCAAGAAGATCAACAAGCTTTTTCCACTTACGCAGGGCCCGTTTTTGGGGTTAGTATAGAAAGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa40058
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000111435 Nonsense 848 1085 19 25
Genomic Location (Zv9):
Chromosome 3 (position 23262492)
Other Location(s):
Assembly Chromosome Position
GRCz10 3 22840703
GRCz11 3 22971251
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TGCTTTTTATAGGATATCCATCATGGAAACGGGACCCAGCAGGCTTTCTA[T/A]AATGACCCCAATGTGTTATATATTTCTCTGCATCGTTATGACGATGGCAA
Long Flanking Sequence:
GTAAAATTTGGTGAAGGGATGATTGTGTGGGGTTATTTTGTTAGGTTGTTGGGATTGGTCCTTAGTTCCAGTAAAAGGAACTCTTGATGCTTTAGCATACCAAGACATTTTGGACAATATCATGACCCTTTTTAATCTAACATTACTGCCCACCAGTGCACAAATTAACACTCTTAAAGACATAGATGATTGTTTTGGGTGTGAAGGAACTTGTCTGGTCTGCACAGAGTCCTGAACATAACCCAATTGAACATATTTGGGATAATTCAAACATTGCAACTTGGTCAAATATCATGTGCCTGGCCTCTGGATCCATCCATGGAGCAGGGAATTTTGTAATGTTATACAATGTCTTGGTGTGTTTTTTAGCAGTTTATGTGTTTTTGAGTTTGATTAATTGTCATCGACATGTTTACCGGACCACAAATACCAAAATCAGACTTTACTCATTGCTTTTTATAGGATATCCATCATGGAAACGGGACCCAGCAGGCTTTCTA[T/A]AATGACCCCAATGTGTTATATATTTCTCTGCATCGTTATGACGATGGCAACTTCTTCCCTGGCAGTGGCGCTCCTGAGGAGGTAACAACATTTCCATCACATTATTTTGTGGCGTATGACTAAAGTTGCCATTGTTTTTCAATATGGCTTGCTCTGCAGGTGGGTGTGGGTCCAGGAGAGGGCTTTAATGTCAACATTGCCTGGACAGGTGGAGTGGAGCCACCTATGGGTGATGTGGAGTATCTAACCGCCTTCAGGTGACATCTGCACTTCCTGTCTGTCTGTCAATAATAGAGATAAGAAAGCTGATGCTAGATTTAATCTCACTTTCAGAAACTCTTGCCTGTCAGCTTAAAAAGGTTAAACATAGGTCCAGAGAGGACTTGTCAAAAACATCCTAAAACATCAAATTATTAAGATTTTTTTTACTTTTACACTGAAATAGATTTTAGTAGATGACAGTTTGTTTACATATTTATTCATTGCTCAATAGTAGAAAA
Associated Phenotype:
Not determined