ZMP

hes2.1

Ensembl ID:

ENSDARG00000074897

ZFIN ID:

ZDB-GENE-081104-104

Description:

hypothetical protein LOC559147 [Source:RefSeq peptide;Acc:NP_001116717]

Human Orthologue:

HES2

Human Description:

hairy and enhancer of split 2 (Drosophila) [Source:HGNC Symbol;Acc:16005]

Mouse Orthologue:

Hes2

Mouse Description:

hairy and enhancer of split 2 (Drosophila) Gene [Source:MGI Symbol;Acc:MGI:1098624]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa34488	Essential Splice Site	Mutation detected in F1 DNA	Not yet available
sa7157	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa34488

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > G

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111075	Essential Splice Site	63	195	2	5
ENSDART00000143321	Essential Splice Site	63	150	2	5

Genomic Location (Zv9):

Chromosome 8 (position 49082038)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	46935433
GRCz11	8	46925899

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CAGCCTCAATCACCTAAAAACTCTTATTCTCCCACTGGTCGGCAAAGATG[T/G]AAGTATCTTAACTTTGTTTCTTTGGCAATACATACAATACTAATAAATCC

Long Flanking Sequence:

TCAACAGATGGCAACTTATGGGACAGCCAGATCAAATCTTTTCTCCTCGGCGTCAAACTAAACGCGACACAATAGATCGGAGACCCTCCCTCCACGCCAAAGGGGACTATAAAAGACCTCTCTCTTCCATCCTGACCACAAAACTCTCAAACTCCTCTCTCAAGAGCACAACTAGAGAAATCAACCGATTAAATCATGACTCCAAACATTATTACCGAAGCTCATCCCCACTCATTCGGCTCTCGAATGACTGTAGCTCAGAGAAAAGAGGCACATGAACTGAGAAAGGTGAGGGCGATTTTCAGTTCTTTTAATGAACACACCTGAATCATTTAATGGTTCTTATAAAATCCTAAAACACACACTCATACTGACCCACTTCTTTCTTCCTCTTTTTCCCCAGACTCTCAAGCCATTGATGGAAAAGAGAAGGCGGGCTCGCATTAACGACAGCCTCAATCACCTAAAAACTCTTATTCTCCCACTGGTCGGCAAAGATG[T/G]AAGTATCTTAACTTTGTTTCTTTGGCAATACATACAATACTAATAAATCCAAGTTTATGTCAGTGTCTGAACAATATGCTAATCTTTGAAATCACTTTAATTCGTAGGCTTCACGTTATTCAAAGCTCGAGAAAGCCGACATTCTTGAAATGACCGTCCGGTTCCTGAGAGATCTTCCTTCCTCATCAGCTAAAGGTGAGTTAGCTATCAAATTTGCCCTTTTCCACATTTTTATCGTTTGTTTATGGTCTGCATTTTTTCAAAACGAATACTTTATTAATTGTCTCCCTTTTTCTCCTTAAAGGTCAAACAGACAGCTATAAAGAGGGCTATAAAGCCTGCTTGCAGCGCATATCTACGATGCTCCCGCAGTCAAACCTGGAAACAGAAGCCCATCAGCGCGTCAGCGAGTTCATCCACACTGTTAGACATTTCAAAGGGTTTTTACAGTAACTTACTGGCAACACTGTTGCCAGTAAGTTACTGTATTTTAGATTTAC

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa7157

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

T > G

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111075	Nonsense	98	195	4	5
ENSDART00000143321	Nonsense	98	150	4	5

Genomic Location (Zv9):

Chromosome 8 (position 49081717)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	46935112
GRCz11	8	46925578

KASP Assay ID:

554-4545.1 (used for ordering genotyping assays)

KASP Sequence:

ACTTTATTAATTKTCTCCCTTTTTCTCCTTAAAGGTCAAACAGACAGCTA[T/G]AAAGAGGGCTATAAAGCCTGCTTGCAGCGCATATCTACGATGCTCCCGCA

Long Flanking Sequence:

ACCTGAATCATTTAATGGTTCTTATAAAATCCTAAAACACACACTCATACTGACCCACTTCTTTCTTCCTCTTTTTCCCCAGACTCTCAAGCCATTGATGGAAAAGAGAAGGCGGGCTCGCATTAACGACAGCCTCAATCACCTAAAAACTCTTATTCTCCCACTGGTCGGCAAAGATGTAAGTATCTTAACTTTGTTTCTTTGGCAATACATACAATACTAATAAATCCAAGTTTATGTCAGTGTCTGAACAATATGCTAATCTTTGAAATCACTTTAATTCGTAGGCTTCACGTTATTCAAAGCTCGAGAAAGCCGACATTCTTGAAATGACCGTCCGGTTCCTGAGAGATCTTCCTTCCTCATCAGCTAAAGGTGAGTTAGCTATCAAATTTGCCCTTTTCCACATTTTTATCGTTTGTTTATGGTCTGCATTTTTTCAAAACGAATACTTTATTAATTGTCTCCCTTTTTCTCCTTAAAGGTCAAACAGACAGCTA[T/G]AAAGAGGGCTATAAAGCCTGCTTGCAGCGCATATCTACGATGCTCCCGCAGTCAAACCTGGAAACAGAAGCCCATCAGCGCGTCAGCGAGTTCATCCACACTGTTAGACATTTCAAAGGGTTTTTACAGTAACTTACTGGCAACACTGTTGCCAGTAAGTTACTGTATTTTAGATTTACAGTATACAACTGTAAATCCGTTTACAGCATGTTACTGTAGTGTCTGAAAATGGTTAACTACTGTAAAAACCTAAGTTAACAGTTAGCTACTGTAAACCTTTTAATTTTGTCCTAAATATTTTATAATATAATTTTATTAATATTATTTTAATACTATAGACCTAAAAAAGACACAATTACAAAATATTAACAAAATAAACACTCTTTATTTAAAACATTGGAGATGCTTAAAACAAGCTTAAAAATGTGTAAAAACATTACATTTCAATCATTCAAAATATTTTATTTTAAGAAAAAAAAACATTGAAAATGACAAAGCAC

Associated Phenotype:

Not determined