ZMP

si:dkey-11p10.8

Ensembl ID:

ENSDARG00000074843

ZFIN ID:

ZDB-GENE-030131-3235

Human Orthologue:

PHLDB2

Human Description:

pleckstrin homology-like domain, family B, member 2 [Source:HGNC Symbol;Acc:29573]

Mouse Orthologue:

Phldb2

Mouse Description:

pleckstrin homology-like domain, family B, member 2 Gene [Source:MGI Symbol;Acc:MGI:2444981]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa37899	Nonsense	Available for shipment	Available now
sa24511	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa37899

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111552	Nonsense	746	1361	9	22
ENSDART00000141601	Nonsense	591	1163	6	18

Genomic Location (Zv9):

Chromosome 24 (position 25728398)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	24	24975276
GRCz11	24	25120450

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGCAGGATTCGGAGATGGCTCAGCTGCAGCAGGAAAAAGACACTCTGGAG[C/T]AGCTTAAAGAAAAGATGGCCGAAATCGAAAACAAAGCACAGACAGACAAA

Long Flanking Sequence:

AGTTCAGATGACCCAAAGCTCAAGTGAAAGCTATAGCTAAAGTGGGCCTCAAAGTAGAAACTCCCGTCTCTTGATTAATGATTCGCAGGTAAGTTAGTCTTCTGCCAGTAGTTCCTGCGAGGTCAGCTGTTCCATTACTAGCACATTCAACAAACCCGCACTGTCAGTGATGAGTTCAAGTTTTATAAGGTTGAGGTTTCATTGGCTCAGAATGTGGGCCTCCTTTTTATATGTGTGAAATGAGGCACCATCTTGGTGGTCCAGAATGTAGTGGTATTACATCACTGTTTGCTGTGAAATCATTGATGTTGTTGCAGCATTAAAAATCAGTGACTTCAATGACTGATTTTTTTAATGATGATTGATGTTTTTTATATGTTTGAAATGTTAAAATTAAATATATATTTGTGTGTGTTTAGTTGGAAGTGGAGCGGGCTCTGCTGGAAGGCGAGCAGGATTCGGAGATGGCTCAGCTGCAGCAGGAAAAAGACACTCTGGAG[C/T]AGCTTAAAGAAAAGATGGCCGAAATCGAAAACAAAGCACAGACAGACAAATCTCAGGTATGTTGCCATGTATCTTCAGGGTTAGTTAGCAGTTATCTAAATGAAGCAATGCTACACTGTAAAAATATATGTGATATGATGAAAGATGATAAGTTAATCAAGTGTCAACTATGTTATGCAAAGCTTAACTTAATATGTTTAGTCAGTTTGATTGATATAAGTTGAGAGGACTTGAAATGTTAGTTTAATTCAACTGAAAAAATAAAGCTGCAAGAATATCCTGAACTCAAATGCACTCTGCTAAACATTTGGTGGTGATTAGGTACATTAGGTAGATTATTCAAACAAATAAATCGCTTTGTTGGTTTGTGGTCTGTAAGATTTATTTTGAAAGGTATTAATAATTTATTTAGAAAGGATGCTTTCAATTGATTGAAGTCAACGCAAGGATGGTTGCAAAACATTCATTACTCCAAATGAATGCTTTAAGCAAACTTTCTG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa24511

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111552	Essential Splice Site	1032	1361	15	22
ENSDART00000141601	Essential Splice Site	834	1163	11	18

Genomic Location (Zv9):

Chromosome 24 (position 25715473)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	24	24962351
GRCz11	24	25107525

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

TTACCCCACAATTCACCTGTGCCACCCTGGGTCGCAACATATCCCCTAAA[G/A]TAAGAACACACTATTCATTCATTTATTTTCTTTTCGGCTTAGTCCCTTTA

Long Flanking Sequence:

TTTTTCATGATATGACTCTTTTTAAACTACCTAGTCTTATCAGCTCACCTTCTTCTGGCATTATTTTCAGATTTTCTCTTTTCCTCTCTTTGCCAAAGCTCTCTCCCTCTTCCAGTCCACTGTCCTCCTCCATCCTTTCCTCTTCCTCTTTCACTGCATGCTCTCATCCAAACCCTAAACCTCCCTCCGTGCACTGGCCAGAAGACATGGTCACCTTCCTCAATCCTTCTCCTCCTCCTCCTCCTTTGCCTGCAAAAAAAATGCGCCGCCACAGGCAGGTAATCCTTCTGAGTGTGTCTGTACATATGAATGTAATTATCACTGAAATGACTTATCTTTAACCTTCTGTTCCTCAGCATTTTCGCAGTCTAGAGGAAAGAAAACGGTACGGTAAAGAAGGCGGAGCTCATTTGAGTGACACTCTTCCACGCAAGAAAACCCAGCCCACTATTACCCCACAATTCACCTGTGCCACCCTGGGTCGCAACATATCCCCTAAA[G/A]TAAGAACACACTATTCATTCATTTATTTTCTTTTCGGCTTAGTCCCTTTATTAATCTGGGGTCGCCGCAGCAGAATGAACCGCCAAGAATAAACAAAAGCGGATGCCCTTCCAGCTGCAACCCATCACTGGGAAACAACTATACACCCTTATTCACACATACACTATGGACAATTTAGTTTACCCAATTCACCTATAGCGCATGTATTTGGACTTTTGGGGGAAACCGGAGCACCCGGAGAACACTCACGCCAACACGGGGAGAACATGCAAACTCCAAACAGAGCTGCCAACTGACCCAGCCGGGACTCGAACCAGTGACCTTCTTGCTGTGAGGCAACAGCCCTAAACACTGAGCCACCATGCCACCAATACATGATACACTAATGATGACAATTTTGAACTGAATGGTTAAAAAAAATTGCATAAAAATTTAAAAGACAACATTTGAAAAAAAAAAAACATGAAAAAAATTTTACCGACCTCAAATTTTGAATGTTT

Associated Phenotype:

Not determined