Busch Lab

ZMP

tfb2m

Ensembl ID:
ENSDARG00000074756
ZFIN ID:
ZDB-GENE-070521-3
Description:
dimethyladenosine transferase 2, mitochondrial [Source:RefSeq peptide;Acc:NP_001107089]
Human Orthologue:
TFB2M
Human Description:
transcription factor B2, mitochondrial [Source:HGNC Symbol;Acc:18559]
Mouse Orthologues:
AC122891.1, Tfb2m
Mouse Description:
transcription factor B2, mitochondrial Gene [Source:MGI Symbol;Acc:MGI:107937]

Alleles

There are 4 alleles of this gene:

Allele Name Consequence Status Availability
sa10078 Nonsense Available for shipment Available now
sa2933 Nonsense F2 line generated Not yet available
sa36345 Nonsense Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa10078
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
G > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110058 Nonsense 219 437 4 10
Genomic Location (Zv9):
Chromosome 17 (position 11927598)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 11910120
GRCz11 17 12064186
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AACCCCCCGTCATGTACTCAGAAAAGCTCTTCTCTGACCTTGCCATCTCW[G/T]AAGTACCGTGGACAGCAGGTTAGTGAACCAAACATTCAGAATAATATGAG
Long Flanking Sequence:
ATTATGTAGGAAATAAGACCTACATTTTTTTGTTCTCATGAACACATGGGATGGAAGTATTGTTGTATTTACAAATAATTTATGCAATATTACATATTTATGTTTGAGAAAATCTTGCAACAAATATCCAAGGATGTTTCTAACATCCTTGACAACCTCAACCTCTTTTGAATCCAGTTGGTCAAAAGACCAAGAGGGGAATTTAGATTTCTTAGTTTGTGACATCTTTAATGTTAGTTAAATCATTAAAAAAACGCTACAAAATGTACACAATAGCAACAATCTCACTGTAAAGGCAAACTTTTCTGTGATTTACAGTCTAATATGGTCATCTTCCACACCCATAAACTGTTTTAATTTTAAAGGAACTGGAGAGCAGACTGGAGGGGCAGCTGGATGTGGTTCATTGTGATTTCTTCAAACTGGACCCCATTGGCAACGGCATCATGAAACCCCCCGTCATGTACTCAGAAAAGCTCTTCTCTGACCTTGCCATCTCT[G/T]AAGTACCGTGGACAGCAGGTTAGTGAACCAAACATTCAGAATAATATGAGCAGATAATAACAAGAAGATTAGATGGATTTGCTCTTCAGTGTTTGGACTTTCAGCAGTGAAATTTAAACCAGACTGAACTGAACTTCAACTCTGAAAACTGGACTGACAGTTTCGATTTACTTAAACTTCTTTCTTAAGCTGCTTTGATACAATCTACATTGTAAAAGCGCTACAGAAATAAAGATTAATTGAATTGAATTAGCACAACAATATATAACGGTTATTTTACATTGTAAAACTACTCAAATAGTAAAGCATGATAATTGTAACACCTAAGTTGCTTGTTTCATTTCCAACAAGAACTAAATATAAAAAACCAATGTCACTTTTGCTGAAAATGTCTGCCAAATTCATAAATGTGATCCTGGAGTCTTATGTTGCACAGGTATATTTGTAGAAATTGCCAACAATACGTTGTTATGAGTCTCTTTCGCTTATGACTAAGGTCA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa2933
Status:
F2 line generated
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110058 Nonsense 333 437 8 10
ENSDART00000110058 Nonsense 333 437 8 10
Genomic Location (Zv9):
Chromosome 17 (position 11935696)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 11918218
GRCz11 17 12072284
KASP Assay ID:
554-3434.1 (used for ordering genotyping assays)
KASP Sequence:
ATTATATACTTTTTTTTTTTTGAACAGCTATCCCAGAGTGAAAACCTTTG[T/A]CTGGTGCGKATCACCCCACGCGAGGACTTGTTTAGCTCTCATTTAACTCC
Long Flanking Sequence:
TGCTTTTTTTAATCAACGATCAAATAAATATTATACATGCAAATAGCATTTAAAGCACAAATGTGGCAGTATTTATATTTCTGTCTAAATCTAGTTATGAAATTGTGTTTTAATTACTCCAATTTGCTATTGAAATATATTCCTCACAGTGGCTTTCATAACTTGATTTCATGACAGATTAATTTAAATGTATACATTAATTAAGATATAAGAGATAACGACTATATATAGGATAAGATGCAAATATGTACACAAAAAAACTTGTAACTTGGAATGGTCCAGAAGTGTGTTTTGTGACTAAAGTGTGACTAAAATTTTGATCTTGGGATTTATTTCATAAAGTTAATTAATTAATTAATTGTATATTAAATATAGAGCTATAATTATTGTGTATAGAACTATATTTATCAAATTTAGTCCTATACATGCATGCCCAACCAAAAGACTCTCATTATATACTTTTTTTTTTTTGAACAGCTATCCCAGAGTGAAAACCTTTG[T/A]CTGGTGCGTATCACCCCACGCGAGGACTTGTTTAGCTCTCATTTAACTCCCTTGAACGGCAGCACACTGGTCCTGATGGTGAAACAATGCCTTGCCAAGAGAAAAGGCAAACTGATTCAACAAATTAAGTAAGTTTATGCATTTTTGGACCTCTTAATGCGTCTTACTCCTGTTATTGCATGCATTTTTGGTTGATCGAATGACAAGTTGTAGACAGGAGGACACCTGTCTATACCTGCTGTTTAAATCCCTTATCATTGTCCACTTTTCGGATTAGAGATTTCTGATTATGGTGTGTGTATAGGCCACTTCCCATAGCTCATAGTAGCACAGTACTGTATAGTAATATAGTAAGGCTTGTAATCTGACTTTTTTTTTGTCTTCTGTCTTCATAAGCTCATGGAGTCCTGGCATGGGATCGGAGTTGATCTCAAATCTTGGTTTTCTTGACGACACACTGACAGGTGACGTTTACCCTGATGAGTACAAGCGTCTCTTTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa36345
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000110058 Nonsense 425 437 9 10
Genomic Location (Zv9):
Chromosome 17 (position 11936240)
Other Location(s):
Assembly Chromosome Position
GRCz10 17 11918762
GRCz11 17 12072828
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CTCTTTGAGCTGATGGAACAGTCTGGAAGCTTCGCTGAGAGCTGGCTTTA[T/A]CAGGAGACGCTGGAAACCACAAAAATAGGCCACGGTTAACACCACCAGAG
Long Flanking Sequence:
TAACTCCCTTGAACGGCAGCACACTGGTCCTGATGGTGAAACAATGCCTTGCCAAGAGAAAAGGCAAACTGATTCAACAAATTAAGTAAGTTTATGCATTTTTGGACCTCTTAATGCGTCTTACTCCTGTTATTGCATGCATTTTTGGTTGATCGAATGACAAGTTGTAGACAGGAGGACACCTGTCTATACCTGCTGTTTAAATCCCTTATCATTGTCCACTTTTCGGATTAGAGATTTCTGATTATGGTGTGTGTATAGGCCACTTCCCATAGCTCATAGTAGCACAGTACTGTATAGTAATATAGTAAGGCTTGTAATCTGACTTTTTTTTTGTCTTCTGTCTTCATAAGCTCATGGAGTCCTGGCATGGGATCGGAGTTGATCTCAAATCTTGGTTTTCTTGACGACACACTGACAGGTGACGTTTACCCTGATGAGTACAAGCGTCTCTTTGAGCTGATGGAACAGTCTGGAAGCTTCGCTGAGAGCTGGCTTTA[T/A]CAGGAGACGCTGGAAACCACAAAAATAGGCCACGGTTAACACCACCAGAGACATTCGCCTTCACAACTGATCATGGAGAAAACAGAAAAAAAAAAGTGTTGTTTTATATGGAAGAAAGACAACTAGTGAAGAAAAACACTATCTTGCTTTACAAACAAACTCTTAATGATGGCTAATATGTAGACAGACTTGTCTATAACAGACTTTACATATTGATAAAGTTATATTTAGTCAAATGACGGGGACTGGAGAAGCTGGTGTTGGAGACATGAATGATACTGAACTCATGAAGCCAATAACTATTATGTGTGTACTGCATATACACCGAATACTTCCTTAATCTCTTTGATTCGAATAGGAGATCTTAAATATGAATAGAATTAAGCGACTTGTAATCCTAATGATTGCATTAGCACAGCCAGTTGAGATGTACATTTGCAAAGTGCTCATGTTTTTGTGTTTTCATATTTAAATGTTTGCTGTATTTAATAAGATGATTT
Associated Phenotype:
Not determined