ZMP

si:busm1-104n07.3

Ensembl ID:

ENSDARG00000074510

ZFIN ID:

ZDB-GENE-030616-99

Description:

Novel protein similar to MHC class II beta chain [Source:UniProtKB/TrEMBL;Acc:Q8MGS5]

Human Orthologues:

HLA-DOB, HLA-DPB1, HLA-DPB2, HLA-DQB1, HLA-DQB2, HLA-DRB1, HLA-DRB5

Human Descriptions:

major histocompatibility complex, class II, DO beta [Source:HGNC Symbol;Acc:4937]
major histocompatibility complex, class II, DP beta 1 [Source:HGNC Symbol;Acc:4940]
major histocompatibility complex, class II, DP beta 2 (pseudogene) [Source:HGNC Symbol;Acc:4941]
major histocompatibility complex, class II, DQ beta 1 [Source:HGNC Symbol;Acc:4944]
major histocompatibility complex, class II, DQ beta 2 [Source:HGNC Symbol;Acc:4945]
major histocompatibility complex, class II, DR beta 1 [Source:HGNC Symbol;Acc:4948]
major histocompatibility complex, class II, DR beta 5 [Source:HGNC Symbol;Acc:4953]

Mouse Orthologues:

H2-Ab1, H2-Eb1, H2-Eb2, H2-Ob

Mouse Descriptions:

histocompatibility 2, O region beta locus Gene [Source:MGI Symbol;Acc:MGI:95925]
histocompatibility 2, class II antigen A, beta 1 Gene [Source:MGI Symbol;Acc:MGI:103070]
histocompatibility 2, class II antigen E beta Gene [Source:MGI Symbol;Acc:MGI:95901]
histocompatibility 2, class II antigen E beta2 Gene [Source:MGI Symbol;Acc:MGI:95902]

Alleles

There is 1 allele of this gene:

Allele Name	Consequence	Status	Availability
sa1580	Essential Splice Site	Available for shipment	Available now

Mutation Details

Allele Name:

sa1580

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC

Mutation:

A > C

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000097932	Essential Splice Site	116	250	3	5
ENSDART00000148323	Essential Splice Site	131	242	3	4

Genomic Location (Zv9):

Chromosome 8 (position 37480456)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	8	36336503
GRCz11	8	36368937

KASP Assay ID:

554-1523.1 (used for ordering genotyping assays)

KASP Sequence:

TTTCCTMATTTGTAAAAGCAGCAAATTTAGAATGTTGCTCTTGTTGATTT[A/C]GTGAAACCAAAGGTTAAGCTCACTTTAGTGAAGCCAGCTGGTGGAAGACA

Long Flanking Sequence:

TTTCAACATGCAAAATATCCCTGAATTAAAGAGATCATTGAATAAACAATGGCAATTTCTCAAGTGACATTTGGAAAGCAGAAGTAAACTCTACCTAGGTAAACCACTTTTTTTCCCTACTTGAATAGGTATATCAAAAAAAAAAAAAAAAAATATATATATATATATATATATATATATATATATATATATATATATTTTTTTTTTTCTTTCTAAATTTTTCAACACAAACGTGATAGTTTCTCCTTAAAAGTGTCACATTTCAAATAATATTTGGAAAGAAAAATACCACATTACAGCCATGTTGTTGCTAATGTTATTAAACCCAATGATCAGAAATTATACATTGCAACACTTAATGACCTACGTACATAACTTTTGTAAGAATATAATCTATACGTATATGAGTACATATCATAATGCTGCCATTTCATTTGTTAAAAGCCACAATTTCCTCATTTGTAAAAGCAGCAAATTTAGAATGTTGCTCTTGTTGATTT[A/C]GTGAAACCAAAGGTTAAGCTCACTTTAGTGAAGCCAGCTGGTGGAAGACATCCTGCAGTTTTGATGTGCAGCGCGTATGAATTTTATCCTCCACACATCAGAGTGTACTGGCTGAGAAATGGTGAAGTGATAACCTCTGATGTGACATCAACTATGGAGATGGCTGATGGAGACTGGTATTACCAGATTCACTCTGAGCTGGAGTACAGCCCAAAATCTGGAGAAAGGATCTCATGTGGGATTGAACATGCCAGCTCTAATAAACCCATCATTACAGAGTGGGGTAAGCGGAATATGCTTACTGTCATATTAGCATTGTTTGTGGGACAATTTGACATACTATTGTATCCTACAGATTCATCTCGTCCTGCGTCTGAGAGGAATAAAATCGCCATTGGGGCATCTGGTGTAGTTCTGGGAATCATCATCCCAGCTATATGTTTTATTTACTACAAGAAAACTGCAGGTTAGTTTCAATTCATTTAACTTTTTTTTCTATT

Associated Phenotype:

Normal

Stage	Entity	Quality	Tag
Larval:Day 5 ZFS:0000037	whole organism ZFA:0001094	quality PATO:0000001	normal PATO:0000461