ZMP

si:dkey-26i13.2

Ensembl ID:

ENSDARG00000074213

ZFIN ID:

ZDB-GENE-090312-175

Human Orthologue:

EIF3B

Human Description:

eukaryotic translation initiation factor 3, subunit B [Source:HGNC Symbol;Acc:3280]

Mouse Orthologue:

Eif3b

Mouse Description:

eukaryotic translation initiation factor 3, subunit B Gene [Source:MGI Symbol;Acc:MGI:106478]

Alleles

There are 3 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa32612	Nonsense	Mutation detected in F1 DNA	Not yet available
sa6576	Nonsense	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa32612

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

C > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111041	Nonsense	192	594	5	16
ENSDART00000134531	Nonsense	149	648	4	17

The following transcripts of ENSDARG00000074213 do not overlap with this mutation:

ENSDART00000142045

Genomic Location (Zv9):

Chromosome 1 (position 10874352)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	11006429
GRCz11	1	11693229

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

AGGATCCAGACTGTCGTGATCAATACAGTGTAATCTATGAGTCGGGAGAG[C/T]GAACCGCCATATTCTCGAATGACCCAAAGGAGCCGATACTGGTGGAAGAG

Long Flanking Sequence:

ACAAATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATGTAGTAGTTAAGGCTATTTGATTTAAAGTGAGGCCAACTCTTTTGTCAGCTTTAAAAAATAAGAATGATTTCCTATACAGATATTCATGAATCATGTATCTGTGTGTTTCAGGTACATGAACATCAGTGATCTGTGGGAAACCCCTGAAAAACAGCCATTTAAAGACTTTGTATGTAGTTTTGCATCTGTATTTCTTTATTTTGATAACAATTTATGAATACTTAAAAAACCTAGTTAAAACACATCAGGATATTTTAAACTATTGAAATATGGGTTTATGGCTTGGTATCTGTTTGTTTCAAATGAGAAGCTATTTATGTCTTGGCATTACATCATTTCATTTCCCTTCTCTGTTAACTGCAGGGCAACATGAGGCACTGGCTTGAGGATCCAGACTGTCGTGATCAATACAGTGTAATCTATGAGTCGGGAGAG[C/T]GAACCGCCATATTCTCGAATGACCCAAAGGAGCCGATACTGGTGGAAGAGAGAGCTGTGAGCACATTTACTTGTAAACGGATTTGCTTCAGTGTTATTTTAGTGTTAGAGTTTTGCTTCAGTATTATATAAGCATTTATTTTATGCTATTTCAGTATTTATTCATATTTTAAATTTACTATTAATTTTGTTTTAGCTTATGTTTTTTCGTTTTTGGTTTTCATAGTTCTATTTGGATTGAGCAAAATATAGGGAAATTTAGTTTTCTTTCAATCAAAAAGTATTTACTATCTGCTCCTAAGACATTTCTTAAAGTGTTAAAAATTATTCATAATTTACATTTTACAAATGTGGTAACCTTCTTTTTTCTCATGCCAAAAAAAATGTGTGTGCATGTGTCCATATAATGGCAGTGAATGCACTGATTTGGAAATTTTGTAAAATATCAAAAAGTCTTTACATTTGGAAGCAGACAAATGACATATAGTCTGATAAAAATAA

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa6576

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

A > T

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000111041	Nonsense	572	594	16	16
ENSDART00000134531	Nonsense	530	648	14	17

The following transcripts of ENSDARG00000074213 do not overlap with this mutation:

ENSDART00000142045

Genomic Location (Zv9):

Chromosome 1 (position 10881735)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	1	11013812
GRCz11	1	11700612

KASP Assay ID:

554-4742.1 (used for ordering genotyping assays)

KASP Sequence:

ACGCATACTGGCTTTGGACRTTCCAGGGTCGTCTTCTGCAAAAGAACAAC[A/T]AAGATAGATTCTGCCAATTGCTWYGGAGACCACGCCCTCCTACTTTACTC

Long Flanking Sequence:

TTCCGTTTATTTGAAATAGATATGTTTAGTTACATGTTTCTACTGCCACCTTTTATCAATTTAACTGCAACCAATTTTTGCAGTGCCAGTTTAGAAGATTTGGGGACAAAAGTTTTTATTGAATTTTAATAGCGTGGCTCGTATGGATGCTGTTTTTCTTCTTCTGTGCAGTATGAATGGTGCTCTTGCATTTGTGGACACGTCAGATTGTACCATTATGTACATCGCAGAGCATTACATGGCCTCTGATGTAGAATGGGACCCTACAGGCAGATATGTGGTGACTTCTGTTTCCTGGTGGAGCCACAAGGTAATCTGACATTTAATGTCATGTCGGTAAGAAAGTAAACATTTTTTTTTTTTACTTTAAGTAATTTGATAATCTAACACTCCTAATGTTTCATGTTAACTACTATATATGTGCTTTCATTCTACACACACAGGTGGACAACGCATACTGGCTTTGGACATTCCAGGGTCGTCTTCTGCAAAAGAACAAC[A/T]AAGATAGATTCTGCCAATTGCTATGGAGACCACGCCCTCCTACTTTACTCAGTCAAGAGCAAATAAAGGTGACAGCGTTTAATACTGTTCGCATTAGTAATATCATGGTTTTGTATGGTTTTATTCCTTTATTCTACAATGTGTTCATTTTCCAATTTATTTAGCGATTTTTTTTTCTTTGCTTGTAATCATTAGTTTTTGTATAGTGTTTTATATTTTATTAATATTTATTTTATATATTTTCTATATTCTTAATTAAACATTTGCCCTGAAGATCTAAATAAAGTGACAAATATGATGCTACAGTTCAAGTCAGATTTATTAGACCCTCTTTGATTTTTTAAATATATATTTTTTTAATATTTCCCAAATGATGTTTAACAGAGCAAGGAAATCTTCAATGTATGTCTGATAATATTTTTTCTTCTGGAGAAAGTCTTATTTGTTTTATTTCGGCTAGAATAAAAGCTGGTTTTAATTTTTTTTAAAACAATTTTAAG

Associated Phenotype:

Not determined