Busch Lab

ZMP

tpst1

Ensembl ID:
ENSDARG00000073872
ZFIN ID:
ZDB-GENE-000210-10
Description:
Protein-tyrosine sulfotransferase 1 [Source:UniProtKB/Swiss-Prot;Acc:Q9PTE6]
Human Orthologue:
TPST1
Human Description:
tyrosylprotein sulfotransferase 1 [Source:HGNC Symbol;Acc:12020]
Mouse Orthologue:
Tpst1
Mouse Description:
protein-tyrosine sulfotransferase 1 Gene [Source:MGI Symbol;Acc:MGI:1298231]

Alleles

There are 6 alleles of this gene:

Allele Name Consequence Status Availability
sa22625 Nonsense Available for shipment Available now
sa9716 Nonsense Available for shipment Available now
sa18619 Nonsense Available for shipment Available now
sa19108 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa22625
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114464 Nonsense 23 355 2 5
ENSDART00000128534 Nonsense 23 366 1 4
ENSDART00000136767 None None 28 None 3
ENSDART00000143610 None None 11 None 2
Genomic Location (Zv9):
Chromosome 15 (position 19671405)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 20774031
GRCz11 15 20709763
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
CAGAACTTACTAGTGGCCTGTCTGGTCATTAGCTCGGTCACAGTCTTCTA[T/A]CTGTGTCGCCATGCCATGGACTGCCATCACCGGATAGAGGAGCGCAGCCA
Long Flanking Sequence:
TTTTCTGGGAAATTTTCTTCCCCCTTGGTTTTGAGTGTTTTCCTCAAAAATTCTCAGTTTCGAGGGGTATTTAGCCCTTCCTCTTAGCCCTACACCTTCAAGCTAAAGAGAATTCCGACAGCCTTACCCTTTCATGTAAATGCATAAAACGAGAATTAGGGGTAAGGGGAAGGGCGAAGGGGTAGAATTGGGATTGGGTCTCTGTCATCGTATGAGGAGTCTGATCTGGTGTTTTCTGTGTTTCAGGCCTGATGGGTTCAGGGACTCAACGAGAGCTGCGTACAGCAGATCCCAGCCTCCACTCGCTCCGCTACGGCCAGTCCTGAGTGTCGGGCATTCACCTGAACACACTCTGCCCGACCACACCTTCCCTTTATCTGCTTCTTCCTTGTCTGTGTCCTCCTCTGGCTCCTCCACCCGCACATCCCCGAGATGATTGGCAAGTTAAAGCAGAACTTACTAGTGGCCTGTCTGGTCATTAGCTCGGTCACAGTCTTCTA[T/A]CTGTGTCGCCATGCCATGGACTGCCATCACCGGATAGAGGAGCGCAGCCAGCCCCTGTTGAGCAGCTTGCACGCCACCCTCCGAACAGGCCAAAACCTTAGCACCCCCTTTATCTACAATAAAGACATGCCTCTAATATTTATCGGCGGTGTCCCTCGCAGCGGCACCACTCTAATGAGGGCTATGCTGGACGCTCATCCCGATGTGCGCTGTGGGGAAGAAACCCGCGTAATCCCTCGGATTCTGGCTATGAAGCAGATGTGGAGCCGCTCTGGCCGGGAGAAAATGCGTCTAGATGAAGCCGGAGTGACAGATGAGGTCTTGGACTCGGCCATGCAAGCTTTCCTACTAGAAATCATCGTAAAACACGGGGAACCTGCCAACTACCTGTGTAATAAAGACCCGTTTGCTCTTAAATCACTCACTTATCTGGCCAAGATCTTCCCGCATGCTAAGTTCATTCTTATGGTTCGTGACGGCAGGGCCTCCGTCCACTCCAT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa9716
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114464 Nonsense 40 355 2 5
ENSDART00000128534 Nonsense 40 366 1 4
ENSDART00000136767 None None 28 None 3
ENSDART00000143610 None None 11 None 2
Genomic Location (Zv9):
Chromosome 15 (position 19671356)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 20773982
GRCz11 15 20709714
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
ATCTGTGTCGCCATGCCATGGACTGCCATCACCGGATAGAGGAGCGCAGC[C/T]AGCCCCTGTTGAGCAGCTTGCACGCCACCCTCCGAACAGGCCAAAACCTY
Long Flanking Sequence:
ATTCTCAGTTTCGAGGGGTATTTAGCCCTTCCTCTTAGCCCTACACCTTCAAGCTAAAGAGAATTCCGACAGCCTTACCCTTTCATGTAAATGCATAAAACGAGAATTAGGGGTAAGGGGAAGGGCGAAGGGGTAGAATTGGGATTGGGTCTCTGTCATCGTATGAGGAGTCTGATCTGGTGTTTTCTGTGTTTCAGGCCTGATGGGTTCAGGGACTCAACGAGAGCTGCGTACAGCAGATCCCAGCCTCCACTCGCTCCGCTACGGCCAGTCCTGAGTGTCGGGCATTCACCTGAACACACTCTGCCCGACCACACCTTCCCTTTATCTGCTTCTTCCTTGTCTGTGTCCTCCTCTGGCTCCTCCACCCGCACATCCCCGAGATGATTGGCAAGTTAAAGCAGAACTTACTAGTGGCCTGTCTGGTCATTAGCTCGGTCACAGTCTTCTATCTGTGTCGCCATGCCATGGACTGCCATCACCGGATAGAGGAGCGCAGC[C/T]AGCCCCTGTTGAGCAGCTTGCACGCCACCCTCCGAACAGGCCAAAACCTTAGCACCCCCTTTATCTACAATAAAGACATGCCTCTAATATTTATCGGCGGTGTCCCTCGCAGCGGCACCACTCTAATGAGGGCTATGCTGGACGCTCATCCCGATGTGCGCTGTGGGGAAGAAACCCGCGTAATCCCTCGGATTCTGGCTATGAAGCAGATGTGGAGCCGCTCTGGCCGGGAGAAAATGCGTCTAGATGAAGCCGGAGTGACAGATGAGGTCTTGGACTCGGCCATGCAAGCTTTCCTACTAGAAATCATCGTAAAACACGGGGAACCTGCCAACTACCTGTGTAATAAAGACCCGTTTGCTCTTAAATCACTCACTTATCTGGCCAAGATCTTCCCGCATGCTAAGTTCATTCTTATGGTTCGTGACGGCAGGGCCTCCGTCCACTCCATGATCTCCCGCAAGGTCACCATCGCTGGATTTGACTTGAGCAGCTACCGG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa18619
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114464 Nonsense 166 355 2 5
ENSDART00000128534 Nonsense 166 366 1 4
ENSDART00000136767 None None 28 None 3
ENSDART00000143610 None None 11 None 2
Genomic Location (Zv9):
Chromosome 15 (position 19670976)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 20773602
GRCz11 15 20709334
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
GCCAACTACCTGTGTAATAAAGACCCGTTTGCTCTTAAATCACTSACTTA[T/A]CTGGCCAAGATCTWCCCGCATGCTAAGTTCATTCTTATGRTKCGTGACGG
Long Flanking Sequence:
GAGATGATTGGCAAGTTAAAGCAGAACTTACTAGTGGCCTGTCTGGTCATTAGCTCGGTCACAGTCTTCTATCTGTGTCGCCATGCCATGGACTGCCATCACCGGATAGAGGAGCGCAGCCAGCCCCTGTTGAGCAGCTTGCACGCCACCCTCCGAACAGGCCAAAACCTTAGCACCCCCTTTATCTACAATAAAGACATGCCTCTAATATTTATCGGCGGTGTCCCTCGCAGCGGCACCACTCTAATGAGGGCTATGCTGGACGCTCATCCCGATGTGCGCTGTGGGGAAGAAACCCGCGTAATCCCTCGGATTCTGGCTATGAAGCAGATGTGGAGCCGCTCTGGCCGGGAGAAAATGCGTCTAGATGAAGCCGGAGTGACAGATGAGGTCTTGGACTCGGCCATGCAAGCTTTCCTACTAGAAATCATCGTAAAACACGGGGAACCTGCCAACTACCTGTGTAATAAAGACCCGTTTGCTCTTAAATCACTCACTTA[T/A]CTGGCCAAGATCTTCCCGCATGCTAAGTTCATTCTTATGGTTCGTGACGGCAGGGCCTCCGTCCACTCCATGATCTCCCGCAAGGTCACCATCGCTGGATTTGACTTGAGCAGCTACCGGGACTGTCTTACAAAGTGGAACCGGGCCATAGAGACAATGTACACTCAGTGCCTGGAGGCAGCAGACAAGTGTCTGCCCGTGCACTACGAACAGCTCGTCCTGCACCCTGAAAAGTGGATGAGGACGCTTCTCAGATTCCTCAACATTCCTTGGAACGATGCAGTTCTGCACCACGAGGAGCTCATCGGGAAAGCAGGCGGCGTTTCGCTCTCCAAGTAAGTAATGGGGATTTGTGGATTAGTCAATTAATCAATAATAATTAGCAGAACCACCACAGGGGTCAAATTCACCCTTAGGTGTTTTTCCAATGTACATAACACATTTTCCAAGCCTCACAGTCATTGATTCCCTGTTGTTAAAGTTTGTTTAGATTAAATCTG
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa19108
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000114464 Essential Splice Site None 355 4 5
ENSDART00000128534 None None 366 None 4
ENSDART00000136767 Essential Splice Site None 28 2 3
ENSDART00000143610 Essential Splice Site None 11 1 2
Genomic Location (Zv9):
Chromosome 15 (position 19617513)
Other Location(s):
Assembly Chromosome Position
GRCz10 15 20720139
GRCz11 15 20655871
KASP Assay ID:
2260-8361.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
AAAGCCAAACCCAAGTTAAGAGAAGAGGACGAGTGCTTTATCAGTAGAAG[T/G]GAGTTTTTATCATATTTGCTAGAAGACTTTGCTTCCCTTTTTTCTACCAC
Long Flanking Sequence:
GATCCTGGGATGGAAATGTTGTGAATGCACACATTGGGATACCAATGCTGAAACAATATATTGTGCAGTCCTAGTTTCATGTCCTAGTATCAATGTTTCTATGAAAAACCTTTAAAATCTGAACAACATTTTAAATCCACAGAATGCTTTTATTGTGGAAAATGGTTCTTTAGATTATGAAATTGTTTGGTTCTTTGTCAAACCGTTGACTGAGCGGTTCTTTAAGGAATCCAGAATTGTCCTTCTGTGGCTTCGCTGACACTGAGACAACTTGGTTCATTCATATTTTCACATTTTTAGAGTGTAAACGGGAATTGGAAAGTATTTTGTGAACTAACAATGAATGCTTGACAGCCACTGAAAAGGGTTTATTTGCACTTTATACAGCATTGTGTGCTGGACACATGTGTAACAGATGTTTCTTTTATCACAGCTTCAGAAGTCTCCAGAAAAGCCAAACCCAAGTTAAGAGAAGAGGACGAGTGCTTTATCAGTAGAAG[T/G]GAGTTTTTATCATATTTGCTAGAAGACTTTGCTTCCCTTTTTTCTACCACAGATAAAGTGATTTGAATTAACTTGCATACTGCAATTGATAGAACATGGGATGTTCTAAGAAAAGCATGAAAAATTGCTTTCAGCAATATTATTATAATGTGGTGATAATATTAGATATTATTATTATTATGGTTTTATCAATAATACTGTGTATACATATGTATTATACATTATCATTGTTATGACAAGCAATTAAACACACCCTTATTTACAATAATAACTTAAACAGCAATTAGCAACAATGCTCCTGATCATATTTAAGCATTTTACATATTTTTTAAATTAGTAATTTATATATACATTAACATATATGATATAAAAAATATTATATTACATGGTGCTAAATATATATTAGCCCTTCTATGAAATTTTAATGCATTTAAAATATTTCCCAAGAGCTGTTTAATGAGCGCAGTTCAAAATAAAATAGTCTTAATAAGTAACTTCTA
Associated Phenotype:
Not determined