ZMP

furinb

Ensembl ID:

ENSDARG00000070971

ZFIN ID:

ZDB-GENE-040901-2

Description:

furin B isoform 1 [Source:RefSeq peptide;Acc:NP_001038574]

Human Orthologue:

FURIN

Human Description:

furin (paired basic amino acid cleaving enzyme) [Source:HGNC Symbol;Acc:8568]

Mouse Orthologue:

Furin

Mouse Description:

furin (paired basic amino acid cleaving enzyme) Gene [Source:MGI Symbol;Acc:MGI:97513]

Alleles

There are 2 alleles of this gene:

Allele Name	Consequence	Status	Availability
sa14482	Nonsense	Available for shipment	Available now
sa39474	Essential Splice Site	Mutation detected in F1 DNA	Not yet available

Mutation Details

Allele Name:

sa14482

Status:

Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Order Allele From ZIRC
Order Allele From EZRC

Mutation:

T > A

Consequence:

Nonsense

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000104629	Nonsense	9	823	2	16
ENSDART00000131748	Nonsense	9	111	2	3

Genomic Location (Zv9):

Chromosome 25 (position 9136579)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	25	8831242
GRCz11	25	8908310

KASP Assay ID:

2261-9416.1 (used for ordering genotyping assays)

KASP Sequence:

GCTTGGAGACTACGCACTCCTGTTCATGGAGGGCCGCTTGATCCTGCTGT[T/A]ATTTCTGGGGGCRTACCTGGTCCTCCTGGCTGCTGAGGTGCACTTGATTA

Long Flanking Sequence:

AGGAGGGTGAATAAATGATGAATACAGGATGTCATTTTTCGGCGAACTAAGACGAGCAAAATCAGCAAGAGATAGATCTTATGTCGCTTTTATGAGCTTGCTCTATATACAAGCGTTCAGCTAGTGGGTACAAGTTGTGAAACGCGCAACCTCCTTCTTGTCCTACAAAGTGTTGTTTGTATCCCAGTTTCCCTTGGCGTTACGCTATCAATAGCACTCAAGACACCTTTATGAAAATTTATGATTCTGCACGGCCCCTCTGAGGAGGTTTTCTGACAGAACAGTTATGTTTAGATAACCTGCGCTTTATAGAAAGTGATGGGCCTCTTGGTGTACCAGTATTTCTTCCCTGACACTCTGTCTCGTCTTCTGCAGGTCATTACAGAGCTGAATTCAGAGCGCGGCCCACAGATGCATTAAAACGCAAAGCTCCATCCAGAAGACCAGAACGCTTGGAGACTACGCACTCCTGTTCATGGAGGGCCGCTTGATCCTGCTGT[T/A]ATTTCTGGGGGCGTACCTGGTCCTCCTGGCTGCTGAGGTGCACTTGATTACAGGCCAAGGCATCTACATCAACACGTGGGCCGTCCATATTGAAGGGGGGGTCGAGGAGGCTGAAAGGATTGCACAAAAGCATGGTTTCGTCAGTCACGGGCAGGTGAGTGCTGCTTTATCAAAGATATATATCCTGTTTCTTGTGTATGTGGATGTAATGCTGCATGAGGACTGTAGTGTTGCTCCAATGTATCATTCACCTTCACGCTGTCAAGCTCTGTTGCTTTACACAGGAGGACAGCAGATTTGCACAAACACACACCCACACAATACTCGCACAATTGCGAAGGCCCCTCCGAGAAGTCCTTGTTGATGCTTGTCGTGTCGCCTTTCGTTTGCGTCTATCACTGTTCATTTCATTAAGACGGAGATGCGTCAGCTGTGATTGGGGAAATTAATTTGGGCTTATGTTGTATTCTTTCTCCCTGCTGCCCGCATTGTCTCGTTTG

Associated Phenotype:

Not determined

Mutation Details

Allele Name:

sa39474

Status:

Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.

Availability:

Not yet available

Mutation:

G > A

Consequence:

Essential Splice Site

Transcripts:

Transcript ID	Consequence	Amino Acid Affected	Amino Acid Total	Exon Affected	Exon Total
ENSDART00000104629	Essential Splice Site	352	823	9	16
ENSDART00000131748	None	None	111	None	3

Genomic Location (Zv9):

Chromosome 25 (position 9019307)

Other Location(s):

Assembly	Chromosome	Position
GRCz10	25	8713970
GRCz11	25	8791038

KASP Assay ID:

None (used for ordering genotyping assays)

KASP Sequence:

None

Flanking Sequence:

CCACTCTCGCCACCACCTACAGCAGCGGAAACCTCAACGAGAAACAGATC[G/A]TATGTATTTCACACACATTTAGATGTGCATTTATGTAGACATATGATCAT

Long Flanking Sequence:

ACTCAAGACATTGTAAAATGGATTATTTCTGTATCACTTGCTGGTCTGTTATTGTACATTTCACATCCCAGTTTCAGCTCTGGAGGACCAAAACTGGTCTAATTTTGAGTTAGGTTTTAGCAGCAGTAAGTTTTTATAAACAGAGTTGGCAACCCTGGCTTGTCATTAGCCAATGAAAGCTACAATGAGACCGTCTGCTGTCAATCTACAAAAGACTACTAACTCTTCTATTAATGAAGCATACATTAGCCGTAGTAAATGACCAGTGATGTGCTCATGTGTTCTAGGGTCGATCTGGGCTTGGATCCATCTTCGTTTGGGCATCGGGTAATGGAGGGCGAGAGCGGGACAGCTGCAACTGTGATGGATACACCAACAGCATCTACACGCTCTCCATCAGCAGCACCACACAGTACGGCAGCGTGCCATGGTACAGCGAGGCCTGTTCCTCCACTCTCGCCACCACCTACAGCAGCGGAAACCTCAACGAGAAACAGATC[G/A]TATGTATTTCACACACATTTAGATGTGCATTTATGTAGACATATGATCATGACTCATGCAGTTTCATGAAGCAACATAAACTTTAATGACCCTACAAGTTTCTTAGCATGTCATTACTTAAAATAGAGTAATTCACATTTCAGCATTTGCACCTTGAAGCAGGGGTGTCCAAAGTCGATCCTGGAGGACCGGTGTCCTGCTGACTTTAGCTCCAAAACACCTGCCTGGAGATCTTCTAGTATACCTAGTGAGAGCTTGCTTAGCTGGTTCAGGTGTGTTTGATTAGGGATGGAACTAAACTCTCCATGACACCGGCCCTCCAGGATGACACCCCTGCCTTTTAGGGACAGTTCACCCAAAAATGAACGTTTACGCACTAACCTCAAGCGTTTCCATTCCTTTATGTGTTTCTTTTTTCTGTTTAACACAAAAGAAGACATATTGAAATGAACTGATGTTTGCATTTATTAAATTACATTAATTATAAATTAAAATTAAAT

Associated Phenotype:

Not determined