Busch Lab

ZMP

met

Ensembl ID:
ENSDARG00000070903
ZFIN ID:
ZDB-GENE-041014-1
Description:
met proto-oncogene (hepatocyte growth factor receptor) [Source:RefSeq peptide;Acc:NP_001007125]
Human Orthologue:
MET
Human Description:
met proto-oncogene (hepatocyte growth factor receptor) [Source:HGNC Symbol;Acc:7029]
Mouse Orthologue:
Met
Mouse Description:
met proto-oncogene Gene [Source:MGI Symbol;Acc:MGI:96969]

Alleles

There are 5 alleles of this gene:

Allele Name Consequence Status Availability
sa18672 Nonsense Available for shipment Available now
sa16304 Nonsense Available for shipment Available now
sa17944 Nonsense Available for shipment Available now
sa24650 Nonsense Available for shipment Available now
sa44271 Essential Splice Site Mutation detected in F1 DNA Not yet available

Mutation Details

Allele Name:
sa18672
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
T > A
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104461 Nonsense 241 1382 1 20
Genomic Location (Zv9):
Chromosome 25 (position 19075350)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 18491660
GRCz11 25 18588060
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TTTTCCGAKCAGTCCTACATGGATTTRGCCCCTTCACTGCGGGGGAACTA[T/A]CCACTACATTATGTCTACTCTTTCCAGAGTGGTCCTTATGTWTATTTTCT
Long Flanking Sequence:
AAAGACCTGAAGAAGAAACATGAGTATAAGACTGGACCGGTCCATGAGGGTCCAGACTGCAAGACCCCAACAGATCAATGCAGTGGTTGTGAAAACAAGCCCCGTAACATAAACAACACCAATATGGCCCTGTTAATGGAGACGTTCTATGACCTGGAACTTTTCAGCTGTGGCTCAGTCGGGAATGGCGTCTGCAGTCGTCATGTGTTAGAGGATGGGCCTCTGGGTGCGGAAGTAACTTGCATGTACACCAAAAAGAATGAAGGCAGCAGCCATGGATGCCCAGACTGCCTGGCTGGACCTGCGGGCACTCAGATCCTCAACATAATGAGCGGTCGTGTTGTGAGGTTCTTCGTTGCGAACTCTGAACCTCTTGAGTCAAACGGTCCACGTCTCCACCACACTATTTCCATTAGGAAGATGCGTGAAACTCAAGATGGCTTTGAGTTCTTTTCCGATCAGTCCTACATGGATTTGGCCCCTTCACTGCGGGGGAACTA[T/A]CCACTACATTATGTCTACTCTTTCCAGAGTGGTCCTTATGTATATTTTCTCACCGTCCAACGCGAAGGTGGCAACTCGAAAGCTTTCCACACGAGAATCGTACGCATGTGTTCTTCAGATTCTGAGATCCTGCGTTATGTAGAAATGCCCTTTGAGTGCATTTACTCTGAGCGAAGGAGAAAAAAGCGTTCGGCTCAAGTGGTTTTCAACGTTCTCCAGGCTGCTCATGTGGCCAAAGTTGGCTATGACTTTCAGCAGGAGATGGGCTTGAAAGAAGGAGAGGACGTGCTGTTTGCTGCCTTTGCCCGGAGCAAACCGGACTCACCAGAGCCCACCGCCAGCTCCGCCGTTTGCCTTATCTCCATCACGGACATCAATGAATTCTTCAAGGTTTTCATTCAGAAGGGTTACACAAGGAAACTCCATCACTTTCCAGGATCTGAAGAGAAAACCTTCAACCAGGTAAGAGCTTTCAGCTAAATCCTGAATTATCTCCGATC
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa16304
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104461 Nonsense 547 1382 4 20
Genomic Location (Zv9):
Chromosome 25 (position 19117842)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 18534152
GRCz11 25 18630552
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
TCATGGGYTGTGGATGGTGCAGGACCAGCAACCKGTGCACCAGGGCCCCT[C/T]RATRCCCCCAGTCCCAATGGATCCAGGACTCCTGCCCCCTCCYCATCACC
Long Flanking Sequence:
ATAATGATAAGGTTGCACAATGATGTTTTGCTTCATCAAGGTCCACAGGGAATCATTTAGTTTTGCCTGTTTATATATATTGTTTTTGACACTCAAAGTGCTAGCAGCTGTTTCATATTTTACCAACCCCAGTTTAAGCTAAAAACATTCTTTAAATGGGTCATGAACTGTCGTTTTTTTATAAGTAGAAAATGAGGCCTGAGGATGAGTGAATTAACAGCAAATGTTCGTTTTTTGAGTGAACTCTCCATGTTACAGTAAAACAAGGTGTTACTGTCACACAAAAATGTACTCAACACGTCGCATCATATAAATCCATAAGCTAAATGAATAAATGTAATTTGGAGTGTAATATGGTTTGTGAATGGCTCCAGGTCTCAAAGCTTCCTGTGATCGGGCCTGGATGTGAGCAGTTGTGGACTTGTAGCTCGTGTCTTCTTGCTCCGGGCTTCATGGGCTGTGGATGGTGCAGGACCAGCAACCTGTGCACCAGGGCCCCT[C/T]GATGCCCCCAGTCCCAATGGATCCAGGACTCCTGCCCCCTCCTCATCACCTCGGTAAAAAAGCCTGTCTTGTCACAAACAACATTACCATGGTTTTAAAGCAGCTAATAGCACATAACTAATAGAATAAGTGCTTTCTAAGTATGGAGAGCCCCTATGAAACTCTGACCTTCATTGATTTTGCCTGATTTGCAGTATTTTCAGGGATAAGCAGGGTTTTTTTAAGCAGGGATTTCGAGGTTGTTTTTAAAAGATGTAAATTGATTGTAGATATATCAGAAGGGATTCGTTGGCCATTCTGTGCCTCTTCTAGATTGATGTAAGAGCAGGCCGAACTATATTTGTATTTGTGTCAGATCTCTTTGCTTATGATAAGTGGTGCTCTGAACACTTAATTATTAACTTGGAGCCAAAATGAGCTTTTCGTGTGCCATGTGCTCAAAGCGACGCCATCTGCTTATCAATAAAGAACTAACCGAGCAGAAATCATGCAGAAAAGGA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa17944
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Order Allele From EZRC
Mutation:
A > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104461 Nonsense 592 1382 5 20
Genomic Location (Zv9):
Chromosome 25 (position 19119964)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 18536274
GRCz11 25 18632674
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
AAACCAAYATCACAATCTGTGGCAAAWACTTTGGCTTTAACAAAAAAGAC[A/T]GATTTGATACCAAACTKRTAGACGTGGTGGTTGCTGGAACGAAGTGTAAA
Long Flanking Sequence:
ATTATTATTATTATTATTATTATTATTATTATTATTAAATAATTTAAAAAATATTTTAATATTTCCAATATGTCTGGGTATCTCAAGCTGCAAAGTATGTGAAGTATTTTACCACTAAACACAGAACACAATTCACCTTTAAGATCCTCACCCTCAGCTGGTGGCTCAAGCTTGAGGGCACTTTTAACACAAGAGTCTAAAGCACCGAAAAAAACAGGAAGGTTGTTTTGTTCTCTGTTTTTGTCTCCATCACCATTTACTGGAAGACCCCCTGCCATCAGAGTGCCCATACAACCAAAACAAATTATTGTCAGTGGCCATCAAACCTCATGAGCAGAGAAAGCGCTCAGCATAAAGACTCTCAGCTGGAGGATCGACACTGAAAATGAACTCACAGCTTCTTCCTTCTTTTTTCCTAGATCTCTCCTTCCTCCGCTCCACTCAGAGGTCAAACCAACATCACAATCTGTGGCAAAAACTTTGGCTTTAACAAAAAAGAC[A/T]GATTTGATACCAAACTGATAGACGTGGTGGTTGCTGGAACGAAGTGTAAATTGGAAAGGAAGGACAGTAACAATAATCGGTAAGTAGATTAATAATCCAGGATTTCTGTAAGATCTTAAAAAAGAAATATTGAAATCAAAATTATAGGTCTTAAAAAGTTGTGCATTTGCAGACTAATTTTGATGATTTAAAAAAAATGAAATAATCATTTTATTATACACATTTTTATTCTGCTATTTAAACATTATGCAATGTTTTATGCAATATAATCATTTTAGGCCTTAAAGTCTTAAATTTGCAGAAGCAATAACAAAATTTGGACATTTTAAATTGAAGGATTTTAAGCATTTTAATTTTTTTTATTATATAATATTTTTGTTTATACTCTAGTGTTACGGAATTGTTTCGCTTGTTTCGAAATTACATTTTTGGCTTTATAATTTGAAGAAGCATTGAATAATTTGAAATAATTTAAGTTGAATGAGTTGAATTAATTTTAA
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa24650
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Order Allele From ZIRC
Mutation:
C > T
Consequence:
Nonsense
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104461 Nonsense 645 1382 6 20
Genomic Location (Zv9):
Chromosome 25 (position 19121986)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 18538296
GRCz11 25 18634696
KASP Assay ID:
2261-9591.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GGTCCAGCGTGGACTCTGTGGTCACAGTGCGCAGTGGCAAGGAACAGGCC[C/T]AGAAAGATGGCTTCTCATTTGTGGTAAGAGTCATCACAAATCACAGTATA
Long Flanking Sequence:
AGTGGTATTACAAAGTCTCCAATGCTTGACCCTTAATCAGAAAAAAACACTTGAATGTTTGCAAAATCCTGTAAATACAGCGTACACGTTCACATTCTCCACATATTGCAATCCTGCAGAACATTAAATTGGCTCGCTAAAGTGCTCTATTGTGCATCTCGGCCTCCCATGTCAAACCCTACTACCATTAAGACGCAGTTTTTGTGCCGCCGGACATACCACCCTACAGCCCTGCTATTGTGAGAGGCAAGGAGAAATTCCCTGGGAGAATAGCTCCTGTGTAGTTTCTGCCGAGTAGTACACTTATCATCAAATTAGCGTGGACTAATAGCCTGCTTACTCCACTGGTTCACAAGCGCGTCTTGTTCGCGGGAGATGTTTATGTCTTTATCTGTTGTATGTATGTGTGTGTGTGTGTCAGGTTGGTCTGTGGACTGGATCATGTGAACTGGTCCAGCGTGGACTCTGTGGTCACAGTGCGCAGTGGCAAGGAACAGGCC[C/T]AGAAAGATGGCTTCTCATTTGTGGTAAGAGTCATCACAAATCACAGTATAAACGCTTCAACACACTTTCCAGATATGCATTTTTGACTGCATTCCAGTACTGTGGTTTTGAAGGTGCACAAGGCACAAAGATGTTATTTCTATCTTTCTTTGTAGTCATTTGGACCTTGTGTACTTGCGCTGTGCGATTTTTAATTATCCTTAATAATTGTAGTAGGGCAGCGCAATATATAGTTTCAGCATCTACAGTATATCATAATGTTATCATTTTCAATAATCACATCACAGGATGTTCAATGTTGAGTTTGTATTATATTTATCATTCACATGTGTTTTTGAGGCCTGTGACTGTATAATGATTTTAAAAGCAGTCAGGCATAAGAATTTGTACCATTTGTAACATTAATAACGATAAATTTTATTGAATTTTTTATCTTTATTATTTTATAACTGTACTTAAATACTGTTAGACTTGATGAAAAATGATAAAACACAGTTTTT
Associated Phenotype:
Not determined

Mutation Details

Allele Name:
sa44271
Status:
Mutation detected in F1 DNA
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Not yet available
Mutation:
T > C
Consequence:
Essential Splice Site
Transcripts:
Transcript ID Consequence Amino Acid Affected Amino Acid Total Exon Affected Exon Total
ENSDART00000104461 Essential Splice Site 859 1382 10 20
Genomic Location (Zv9):
Chromosome 25 (position 19136009)
Other Location(s):
Assembly Chromosome Position
GRCz10 25 18552319
GRCz11 25 18648719
KASP Assay ID:
None (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
GAAGCCCACTGTCACACCAAGGGGCAAAAAGAACATTCTGGAGATTAAGG[T/C]GAGCACAACACAGCCCAAAAATATTCAGTTATAACATCTGTAGTGTGGAA
Long Flanking Sequence:
TGTACCCATAGATGAGATGTGAAAGTAATGCGAATACTTAATGTTTGCGCTTATGAAACCTGAACTTAAATCTGCTTAGTCATGTAATCACCCCAACTCTTAAGAAAACATGGCTTCTGGTTAGCCTTGTATAAATCTTACACATGCTGTGCTCCTAAACAAGCAAAAGATAAAGAGAATTGGACACACAAAAGATTGCAACATGCCTCAGCACTGACTTGGCACAGTTATAATAACAGAGATGGCTAATATTCATGTTTGTCTTCTCCTCTATGCCCAGACCTGCAGTCATGATGAGGATAAGAGAAATATCCTTTGCATCACGCCCTCCCTGAAAGGCCTCAGCGTTCAGCCTCCGGTCGCCACTAAAATGACCTTCGTCCTGGATGGTTTTTCCACTGATCAGTACGACCTGCTGTACGTGGAAGATCCCAAATTTGAGGAGTTTCAGAAGCCCACTGTCACACCAAGGGGCAAAAAGAACATTCTGGAGATTAAGG[T/C]GAGCACAACACAGCCCAAAAATATTCAGTTATAACATCTGTAGTGTGGAAGCAATTCAGATGCTTTTAAAGTATGCATTGTCACGCATAGTGTCACTTAAAGTTTTTATTCAGTGTTAAATGCTACCAATGTACATTTAAATACCATTTTATGTGAAATTTATTGTCAAAATGAGGTAAGTAGCAGCAGTTTACTTTAGATCTTGAAAATAAAAAACTAGCAGATGGTTTTAAAATTAAAGTCAGAACTGCAATTTAATACAAACTCATCAGTCATCAAACTCATCAAACATAAGTCCCTCAATAGCCTATTAATAATATTAAAGAGGCTAATATGTACTAACTAGATTAAAAGCCTTTACCATTCAATTTGGAGTGCAGTTGATGACATTTAAATGTTTTTGTAATGTCGCTTCGTGTTTGGTGCAGGCCTCCAAACTGCTTGTTGCAGAAATCTTGTTTCATGTTGTTAGGATATGGTGTAAGGTTGAAATTTGCTCA
Associated Phenotype:
Not determined