ZMP
top1l
Ensembl ID:
ZFIN ID:
Description:
topoisomerase (DNA) I, like [Source:RefSeq peptide;Acc:NP_001037789]
Human Orthologue:
TOP1
Human Description:
topoisomerase (DNA) I [Source:HGNC Symbol;Acc:11986]
Mouse Orthologue:
Top1
Mouse Description:
topoisomerase (DNA) I Gene [Source:MGI Symbol;Acc:MGI:98788]
Alleles
There is 1 allele of this gene:
| Allele Name | Consequence | Status | Availability |
|---|---|---|---|
| sa21911 | Essential Splice Site | Available for shipment | Available now |
Mutation Details
Allele Name:
sa21911
Status:
Available for shipment
For more information about the meaning of this status and other statuses, please see our FAQs.
For more information about the meaning of this status and other statuses, please see our FAQs.
Availability:
Mutation:
T > G
Consequence:
Essential Splice Site
Transcripts:
| Transcript ID | Consequence | Amino Acid Affected | Amino Acid Total | Exon Affected | Exon Total |
|---|---|---|---|---|---|
| ENSDART00000065949 | Essential Splice Site | 601 | 758 | 17 | 21 |
| ENSDART00000065949 | Essential Splice Site | 601 | 758 | 17 | 21 |
The following transcripts of ENSDARG00000070545 do not overlap with this mutation:
Genomic Location (Zv9):
Chromosome 11 (position 26240238)
Other Location(s):
| Assembly | Chromosome | Position |
|---|---|---|
| GRCz10 | 11 | 25069063 |
| GRCz11 | 11 | 25306679 |
KASP Assay ID:
554-3661.1 (used for ordering genotyping assays)
KASP Sequence:
None
Flanking Sequence:
TACAACGCCTCCATCACACTACAGCAGCAGCTGAACGAACTCACTAACTG[T/G]AAGTCCTGCACGCACCAGATTGAGCAGAGCTGCTGGAAACGCATCATATG
Long Flanking Sequence:
AGGTTTTGCTGTTTGCAATCAATTTTTGTGTGTGTTTGGGGTTGTGGTCTTTTGTGCTCTTCAACTGTCCTTGAGTTTGTGAAAGGCTCTGCGCGAATCAAATGTTCACCAGTTTACTGTGCCCTAGTACAAATTGAAATCTTCTCATCTGAGGGCTATTGATTAGCATGGTCGTGTGTTCTGCTTCTGCCTTTTGTGTAAAATCCCTTTTAAATGTTACAGGTTTTCAAAAATCTCCAGCTTTTCATGGAGGATAAGGAGCCAGAGGATGACCTCTTTGACCGTCTCAATGTAAGCAGTCACTTTCACCAGTCTGTTATTTATGGCATGCAGAGGAGAATCTCAATTCTGAATGCATCTCATTAATTGTAAACCATCTTGCAGACCTCCATTTTAAACAAGCATCTTCAGGAGTTGATGGACGGCCTTACGGCTAAAGTGTTCCGTACTTACAACGCCTCCATCACACTACAGCAGCAGCTGAACGAACTCACTAACTG[T/G]AAGTCCTGCACGCACCAGATTGAGCAGAGCTGCTGGAAACGCATCATATGTGACGCTTGTGTGTTTGTTTAGCTGAAGATAATGTTCCTGCGAAGATCCTCTCCTACAATCGGGCCAACCGAGCGGTAGCCATCCTGTGTAACCACCAGAGGGCACCACCAAAGACCTTTGAAAAGTCCATGCAGAATCTTCAGACCAAGGTATGAGACGTTGGCGAACTTGTCCTTATTGTTGTCTTCATGCTGGTATTTCTTTGTTAGCGCAGGGTCTGTTGGACCATCTAAATGTTTGCCTTTCCCGCATTCACTTGTTCATTAAAACCAGATTGACGCAAAGAAGGAGCAGCTTGTTGAAGCTAAAAGAGAGCTGAAAGGTGCCAAGGCTGACGCCAAAGTACGCAAAGATGAGAAATTCAAGAAGTGAGTGTCAAAATATTTGCTTGAAGGGCGCCCAACTGAATTTGGCCTCTTTGTCGCTCATTGTGCATTCGTATGTGATTG
Associated Phenotype:
Not determined